LOCUS       NM_001199198            3697 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens TBC1 domain family member 23 (TBC1D23), transcript
            variant 1, mRNA.
ACCESSION   NM_001199198
VERSION     NM_001199198.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3697)
  AUTHORS   Zhao,L., Deng,H., Yang,Q., Tang,Y., Zhao,J., Li,P., Zhang,S.,
            Yong,X., Li,T., Billadeau,D.D. and Jia,D.
  TITLE     FAM91A1-TBC1D23 complex structure reveals human genetic variations
            susceptible for PCH
  JOURNAL   Proc Natl Acad Sci U S A 120 (45), e2309910120 (2023)
   PUBMED   37903274
  REMARK    GeneRIF: FAM91A1-TBC1D23 complex structure reveals human genetic
            variations susceptible for PCH.
REFERENCE   2  (bases 1 to 3697)
  AUTHORS   Zhang,Y., Su,H., Wudu,M., Ren,H., Xu,Y., Zhang,Q., Jiang,J.,
            Wang,Q., Jiang,X., Zhang,B., Liu,Z., Zou,Z. and Qiu,X.
  TITLE     TBC1 domain family member 23 interacts with Ras-related protein
            Rab-11A to promote poor prognosis of non-small-cell lung cancer via
            beta1-integrin
  JOURNAL   J Cell Mol Med 25 (18), 8821-8835 (2021)
   PUBMED   34363324
  REMARK    GeneRIF: TBC1 domain family member 23 interacts with Ras-related
            protein Rab-11A to promote poor prognosis of non-small-cell lung
            cancer via beta1-integrin.
REFERENCE   3  (bases 1 to 3697)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 3697)
  AUTHORS   Liu,D., Yang,F., Liu,Z., Wang,J., Huang,W., Meng,W.,
            Billadeau,D.D., Sun,Q., Mo,X. and Jia,D.
  TITLE     Structure of TBC1D23 N-terminus reveals a novel role for rhodanese
            domain
  JOURNAL   PLoS Biol 18 (5), e3000746 (2020)
   PUBMED   32453802
  REMARK    GeneRIF: rhodanese domain packs against the TBC domain and forms
            part of the platform to interact with golgin-97/245
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3697)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 3697)
  AUTHORS   Marin-Valencia,I., Gerondopoulos,A., Zaki,M.S., Ben-Omran,T.,
            Almureikhi,M., Demir,E., Guemez-Gamboa,A., Gregor,A., Issa,M.Y.,
            Appelhof,B., Roosing,S., Musaev,D., Rosti,B., Wirth,S., Stanley,V.,
            Baas,F., Barr,F.A. and Gleeson,J.G.
  TITLE     Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of
            Pontocerebellar Hypoplasia
  JOURNAL   Am J Hum Genet 101 (3), 441-450 (2017)
   PUBMED   28823706
  REMARK    GeneRIF: Homozygous Mutations in TBC1D23 gene are associated with
            Non-degenerative Form of Pontocerebellar Hypoplasia.
REFERENCE   7  (bases 1 to 3697)
  AUTHORS   Cheng,C.Y., Schache,M., Ikram,M.K., Young,T.L., Guggenheim,J.A.,
            Vitart,V., MacGregor,S., Verhoeven,V.J., Barathi,V.A., Liao,J.,
            Hysi,P.G., Bailey-Wilson,J.E., St Pourcain,B., Kemp,J.P.,
            McMahon,G., Timpson,N.J., Evans,D.M., Montgomery,G.W., Mishra,A.,
            Wang,Y.X., Wang,J.J., Rochtchina,E., Polasek,O., Wright,A.F.,
            Amin,N., van Leeuwen,E.M., Wilson,J.F., Pennell,C.E., van
            Duijn,C.M., de Jong,P.T., Vingerling,J.R., Zhou,X., Chen,P., Li,R.,
            Tay,W.T., Zheng,Y., Chew,M., Burdon,K.P., Craig,J.E., Iyengar,S.K.,
            Igo,R.P. Jr., Lass,J.H. Jr., Chew,E.Y., Haller,T., Mihailov,E.,
            Metspalu,A., Wedenoja,J., Simpson,C.L., Wojciechowski,R., Hohn,R.,
            Mirshahi,A., Zeller,T., Pfeiffer,N., Lackner,K.J., Bettecken,T.,
            Meitinger,T., Oexle,K., Pirastu,M., Portas,L., Nag,A.,
            Williams,K.M., Yonova-Doing,E., Klein,R., Klein,B.E.,
            Hosseini,S.M., Paterson,A.D., Makela,K.M., Lehtimaki,T.,
            Kahonen,M., Raitakari,O., Yoshimura,N., Matsuda,F., Chen,L.J.,
            Pang,C.P., Yip,S.P., Yap,M.K., Meguro,A., Mizuki,N., Inoko,H.,
            Foster,P.J., Zhao,J.H., Vithana,E., Tai,E.S., Fan,Q., Xu,L.,
            Campbell,H., Fleck,B., Rudan,I., Aung,T., Hofman,A.,
            Uitterlinden,A.G., Bencic,G., Khor,C.C., Forward,H., Parssinen,O.,
            Mitchell,P., Rivadeneira,F., Hewitt,A.W., Williams,C., Oostra,B.A.,
            Teo,Y.Y., Hammond,C.J., Stambolian,D., Mackey,D.A., Klaver,C.C.,
            Wong,T.Y., Saw,S.M. and Baird,P.N.
  CONSRTM   Consortium for Refractive Error and Myopia; Fuchs' Genetics
            Multi-Center Study Group; Wellcome Trust Case Control Consortium 2;
            Diabetes Control and Complications Trial/Epidemiology of Diabetes
            Interventions, and Complications Research Group
  TITLE     Nine loci for ocular axial length identified through genome-wide
            association studies, including shared loci with refractive error
  JOURNAL   Am J Hum Genet 93 (2), 264-277 (2013)
   PUBMED   24144296
REFERENCE   8  (bases 1 to 3697)
  AUTHORS   De Arras,L., Yang,I.V., Lackford,B., Riches,D.W., Prekeris,R.,
            Freedman,J.H., Schwartz,D.A. and Alper,S.
  TITLE     Spatiotemporal inhibition of innate immunity signaling by the
            Tbc1d23 RAB-GAP
  JOURNAL   J Immunol 188 (6), 2905-2913 (2012)
   PUBMED   22312129
REFERENCE   9  (bases 1 to 3697)
  AUTHORS   Fox,C.S., Liu,Y., White,C.C., Feitosa,M., Smith,A.V.,
            Heard-Costa,N., Lohman,K., Johnson,A.D., Foster,M.C.,
            Greenawalt,D.M., Griffin,P., Ding,J., Newman,A.B., Tylavsky,F.,
            Miljkovic,I., Kritchevsky,S.B., Launer,L., Garcia,M.,
            Eiriksdottir,G., Carr,J.J., Gudnason,V., Harris,T.B., Cupples,L.A.
            and Borecki,I.B.
  CONSRTM   GIANT Consortium; MAGIC Consortium; GLGC Consortium
  TITLE     Genome-wide association for abdominal subcutaneous and visceral
            adipose reveals a novel locus for visceral fat in women
  JOURNAL   PLoS Genet 8 (5), e1002695 (2012)
   PUBMED   22589738
REFERENCE   10 (bases 1 to 3697)
  AUTHORS   Ishibashi,K., Kanno,E., Itoh,T. and Fukuda,M.
  TITLE     Identification and characterization of a novel Tre-2/Bub2/Cdc16
            (TBC) protein that possesses Rab3A-GAP activity
  JOURNAL   Genes Cells 14 (1), 41-52 (2009)
   PUBMED   19077034
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA801258.1 and BC020955.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001199198.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020955.1, SRR1660809.202292.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000394144.9/ ENSP00000377700.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                DA801258.1         176-206
            32-3697             BC020955.1         1-3666
FEATURES             Location/Qualifiers
     source          1..3697
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q12.1-q12.2"
     gene            1..3697
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /note="TBC1 domain family member 23"
                     /db_xref="GeneID:55773"
                     /db_xref="HGNC:HGNC:25622"
                     /db_xref="MIM:617687"
     exon            1..80
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..2127
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /note="isoform 1 is encoded by transcript variant 1; HCV
                     nonstructural protein 4A-transactivated protein 1; HCV
                     non-structural protein 4A-transactivated protein 1"
                     /codon_start=1
                     /product="TBC1 domain family member 23 isoform 1"
                     /protein_id="NP_001186127.1"
                     /db_xref="CCDS:CCDS56265.1"
                     /db_xref="GeneID:55773"
                     /db_xref="HGNC:HGNC:25622"
                     /db_xref="MIM:617687"
                     /translation="MAEGEDVPPLPTSSGDGWEKDLEEALEAGGCDLETLRNIIQGRP
                     LPADLRAKVWKIALNVAGKGDSLASWDGILDLPEQNTIHKDCLQFIDQLSVPEEKAAE
                     LLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRD
                     CSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIW
                     DGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLF
                     SLAQYYCSKTPASFRKDNHHLFGSTLLGIKDDDADLSQALCLAISVSEILQANQLQGE
                     GVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSI
                     AGGEHLCFMGSGREEEDMYMNMVLAHFLQKNKEYVSIASGGFMALQQHLADINVDGPE
                     NGYGHWIASTSGSRSSINSVDGESPNGSSDRGMKSLVNKMTVALKTKSVNVREKVISF
                     IENTSTPVDRMSFNLPWPDRSCTERHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDEID
                     SSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTATHMYCLREIV
                     SRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYLIPNAGDA
                     TKAIKQQIMKVLDALES"
     exon            81..192
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            193..298
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            299..503
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            504..627
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            628..752
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            753..799
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            800..903
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1026
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1119
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1290
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1333
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1440
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1580
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..1625
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1714
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1850
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..2045
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..3697
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3674..3679
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /note="hexamer: AATAAA"
     polyA_site      3697
                     /gene="TBC1D23"
                     /gene_synonym="NS4ATP1; PCH11"
                     /note="major polyA site"
ORIGIN      
        1 ggcaaagtga cgtggacgtc aacagcaatg gcggaaggag aagatgtgcc gccgctgcca
       61 acgtcgagcg gcgacggctg ggaaaaagat cttgaagaag ctctggaagc aggaggttgt
      121 gatcttgaaa cgttgagaaa tataattcaa ggaagaccgc tgcctgctga tctgagggcc
      181 aaagtttgga agattgctct gaatgttgca ggaaaaggtg atagtttggc atcatgggat
      241 ggtattttag acttgccaga acagaacact attcacaaag attgcctgca gtttattgac
      301 cagctttcag tgccagagga gaaggcagca gaattacttt tggatattga atctgtaatt
      361 accttttatt gtaaatcacg taacattaaa tatagcacat cccttagctg gatacatcta
      421 ctgaaaccat tggtgcatct tcaactgcca cgcagcgatt tatacaactg cttttatgcc
      481 ataatgaata agtacattcc cagggattgt tcccagaaag ggagaccatt tcatctcttc
      541 aggttgctca tccaatacca tgagcctgag ctttgttctt atcttgatac aaagaaaatt
      601 actccagact cctatgcact caactggctt ggaagtcttt ttgcatgtta ctgttccact
      661 gaagtcactc aggcaatatg ggatggatat ctacaacaag cagatccatt ttttatttat
      721 ttcttaatgt taattatcct tgttaatgca aaagaagtta ttttaacaca agagtcagac
      781 agcaaagaag aagttatcaa gttcttggaa aatactccat ccagtctgaa tatagaagat
      841 atagaagacc ttttctctct ggctcagtat tattgcagca aaacaccggc ttcttttagg
      901 aaggataatc accatctctt tggtagtact ttgttgggaa ttaaggatga tgatgcagat
      961 ctgagtcagg ctctttgtct ggccatctcc gtgtcagaga tccttcaagc gaatcagcta
     1021 caaggggaag gagtccggtt ctttgtggtg gattgccgtc ctgcagaaca atataatgct
     1081 gggcatttat caactgcttt ccacttagat tcagacctga tgcttcagaa tccatctgag
     1141 tttgcacagt cagtaaaatc cttgctggaa gcacagaagc agtccattga gtctggctcc
     1201 atagctggtg gggagcacct ctgttttatg ggcagtggca gggaggaaga agacatgtat
     1261 atgaacatgg tcctggcaca ctttttacag aaaaacaaag aatatgtgag tattgccagt
     1321 ggaggattta tggcactgca gcagcacctg gcagacatta atgtggatgg accagaaaat
     1381 ggatatggcc attggattgc tagtacctca ggctcaagga gcagtatcaa ttctgttgat
     1441 ggtgaatctc ctaatggctc aagtgataga ggaatgaaat cactagtaaa taaaatgact
     1501 gtggctttga agacaaaatc cgttaatgtc agggaaaaag ttatcagttt tatagagaat
     1561 acatcaactc ctgtggatcg aatgtctttc aatcttcctt ggccagacag atcatgtaca
     1621 gagcggcatg tgagcagcag tgacagagtg ggcaagcctt accgtggcgt aaagcctgtt
     1681 ttcagcattg gggatgaaga agaatacgac acagatgaaa ttgacagttc ttcaatgtca
     1741 gatgatgata gaaaagaggt tgtaaacatt cagacttgga taaacaaacc agatgtcaaa
     1801 catcattttc cttgtaaaga agtaaaagaa agtggacaca tgtttcccag tcatctgttg
     1861 gttactgcaa cacatatgta ctgtttaagg gagattgttt cacggaaagg attggcttat
     1921 atacagtctc gacaagcgct gaattctgta gttaaaatta catccaaaaa aaaacatcct
     1981 gaactcatta ccttcaagta tggaaatagc agtgcttcag gaatagaaat cttggcaatc
     2041 gaaaggtatt tgattccaaa tgcaggggat gcaactaaag ccataaaaca gcagatcatg
     2101 aaagttttgg atgctttgga aagttaatat aaaagaaaat tatataaaaa gaaattaaga
     2161 caaccaagag aaacatggac atatacctcc tgactgaata ctaactggag acctttcatt
     2221 tgctcatggg gctgcttaaa tagcaggtct aagaaagtgt aaattattat aatcaatctg
     2281 tggacagtaa actttttaaa aatttttctt ctgcattttg gttttataaa atgatgtatt
     2341 ataaaggtca gttattaaat tactttgaag taactgaccc tgtgccctta tggactaagt
     2401 aagggtacag aatgcagttc tgttttgaag agctgtttta agggaacatg catcactttc
     2461 gggatcaaaa acaactgtac acatacatat ctgcagtgtc ttcactgaaa attagagata
     2521 gaattagttg aagagacttc cttaattgct acattgtttt actcactgag caatatcaga
     2581 aactaaaaca tagattaata attcactcac tgtttctatt cttcttaaaa agagtgaaat
     2641 ctttttaatg gaatggttga agattcctgc caactcaaaa tacagtacag ctagtaaaat
     2701 gttgaaacat cagtttctaa atcacctttg ctccattagc taattttttg gacactaaat
     2761 gcttcaaaga taagaaactt catcctaatg atttctaaag agcagttaaa agcattaaaa
     2821 taagtaggta ggctgttaag attaaaatta acattttggg gacagaattg tgtctgtaaa
     2881 aatgtcattg gttttattac aagcggatta ttttattcat attttaaaac aaatgtttaa
     2941 gccacattga tttatcctca ttgaggatta tggtctgtga ccacagtaat atccacttat
     3001 ataaatgcca aataatcaga gagcttataa agtacaattg tttttgtcat cattttctga
     3061 atttctttct cttcttttgg ttttgtcctc tcattgaagt tccagtggtt tgaaattagt
     3121 tttggacaca ttgtcttaat gtactgaaaa ttgctctgct gtattttgca gcgttcttca
     3181 tttaatttat aatggtccat attagacaca tttggtaaga gaagtccagg aacacattta
     3241 gggccatgga atagtatttt gtaaaatcca tttgggaagt tgcaataccc acaatctgac
     3301 atgtcctaaa atgtaaggga ttatctctaa ggggttgatg ggagaaatat ttagatgtac
     3361 cctgttaaca gccagtcatt ttgatttact tatggaaatc aagtgaataa aaggcaacat
     3421 aatttgggaa attttattct aatatctaat aaaaacagtt tgagtggttg aagacatctg
     3481 catgaaattg cacctaggtg cattacttga tataactctc ccctaaaact gttgtaattg
     3541 cattttttcc cttttcttgg caccccttta gaaatgtact gaagtctcat ttttcaccca
     3601 tttcagccat gggacatttt tcataatatt aatgtaaaga tgtttgtgtt actgtttata
     3661 aattacaatt gtaaataaat tactagtttg cccaaaa
//
