LOCUS       XM_011513666            5763 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens TBC1 domain family member 1 (TBC1D1),
            transcript variant X12, mRNA.
ACCESSION   XM_011513666
VERSION     XM_011513666.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011513666.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5763
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..5763
                     /gene="TBC1D1"
                     /gene_synonym="TBC; TBC1"
                     /note="TBC1 domain family member 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 211 ESTs, 708 long SRA reads, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 20 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23216"
                     /db_xref="HGNC:HGNC:11578"
                     /db_xref="MIM:609850"
     CDS             359..3925
                     /gene="TBC1D1"
                     /gene_synonym="TBC; TBC1"
                     /codon_start=1
                     /product="TBC1 domain family member 1 isoform X12"
                     /protein_id="XP_011511968.1"
                     /db_xref="GeneID:23216"
                     /db_xref="HGNC:HGNC:11578"
                     /db_xref="MIM:609850"
                     /translation="MEPITFTARKHLLSNEVSVDFGLQLVGSLPVHSLTTMPMLPWVV
                     AEVRRLSRQSTRKEPVTKQVRLCVSPSGLRCEPEPGRSQQWDPLIYSSIFECKPQRVH
                     KLIHNSHDPSYFACLIKEDAVHRQSICYVFKADDQTKVPEIISSIRQAGKIARQEELH
                     CPSEFDDTFSKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRGSESPRPNPPH
                     AAPTGSQEPVRRPMRKSFSQPGLRSLAFRKELQDGGLRSSGFFSSFEESDIENHLISG
                     HNIVQPTDIEENRTMLFTKDKSKRLPATLCWLKYSSETIGQSEVYLISPDTKKIALEK
                     NFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFT
                     VAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIF
                     EEVQKLRPRNEQRENELIISFLRCLYEEKQKEHIHIGEMKQTSQMAAENIGSELPPSA
                     TRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSISVDLDSSLSSTLSNTSKEPS
                     VCEKEALPISESSFKLLGSSEDLSSDSESHLPEEPAPLSPQQAFRRRANTLSHFPIEC
                     QEPPQPARGSPGVSQRKLMRYHSVSTETPHERKDFESKANHLGDSGGTPVKTRRHSWR
                     QQIFLRVATPQKACDSSSRYEDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSREL
                     RELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKML
                     STPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKE
                     LLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLS
                     FVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLY
                     NHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHK
                     PLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEEL
                     IDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLK
                     QAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD"
ORIGIN      
        1 ctcctcttcg gctgctgctc ctggtgccgc caccgtccgc cggtgcctgt tgctgccgcc
       61 gccgcgggac ctgctgtgtc ctcagctggg tggagaagag gcgggcgccg agccgagggg
      121 agccccctcc ccgtcccccc gcggcgggaa gagcgcagcc agccgggtgc gatggactcc
      181 ccgcccgccc aggccgtccc caggatgccc ccaagcacct gcgcgtcccg gcccggcccc
      241 gggctctgag cgcgccgcgg cacaggtttc tgcatatgaa gtgtgtaaaa tagattgctt
      301 gatccaaaac agaaaaacag tgataactgt tttgctgagt tcccagaccc ttcccaagat
      361 ggaaccaata acattcacag caaggaaaca tctgctttct aacgaggtct cggtggattt
      421 tggcctgcag ctggtgggct ccctgcctgt gcattccctg accaccatgc ccatgctgcc
      481 ctgggttgtg gctgaggtgc gaagactcag caggcagtcc accagaaagg aacctgtaac
      541 caagcaagtc cggctttgcg tttcaccctc tggactgaga tgtgaacctg agccagggag
      601 aagtcaacag tgggatcccc tgatctattc cagcatcttt gagtgcaagc ctcagcgtgt
      661 tcacaaactg attcacaaca gtcatgaccc aagttacttt gcttgtctga ttaaggaaga
      721 cgctgtccac cggcagagta tctgctatgt gttcaaagcc gatgatcaaa caaaagtgcc
      781 tgagatcatc agctccatcc gtcaggcggg gaagatcgcc cggcaggagg agctgcactg
      841 cccgtccgag ttcgacgaca cgttttccaa gaagttcgag gtgctcttct gcggccgcgt
      901 gacggtggcg cacaagaagg ctccgccggc cctgatcgac gagtgcatcg agaagttcaa
      961 tcacgtcagc ggcagccggg ggtccgagag cccccgcccc aacccgcccc atgccgcgcc
     1021 cacagggagc caggagcctg tgcgcaggcc catgcgcaag tccttctccc agcccggcct
     1081 gcgctcgctg gcctttagga aggagctgca ggatgggggc ctccgaagca gcggcttctt
     1141 cagctccttc gaggagagcg acattgagaa ccacctcatt agcggacaca atattgtgca
     1201 gcccacagat atcgaggaaa atcgaactat gctcttcacg aaggacaaga gtaaaaggct
     1261 acctgccact ctctgctggc tgaaatacag ttcagaaaca attggccagt ctgaagttta
     1321 cctcatcagt cctgacacca aaaaaatagc attggagaaa aattttaagg agatatcctt
     1381 ttgctctcag ggcatcagac acgtggacca ctttgggttt atctgtcggg agtcttccgg
     1441 aggtggcggc tttcattttg tctgttacgt gtttcagtgc acaaatgagg ctctggttga
     1501 tgaaattatg atgaccctga aacaggcctt cacggtggcc gcagtgcagc agacagctaa
     1561 ggcgccagcc cagctgtgtg agggctgccc cctgcaaagc ctgcacaagc tctgtgagag
     1621 gatagaggga atgaattctt ccaaaacaaa actagaactg caaaagcacc tgacgacatt
     1681 aaccaatcag gagcaggcga ctatttttga agaggttcag aaattgagac cgagaaatga
     1741 gcagcgagag aatgaattga ttatttcttt tctgagatgt ttatatgaag agaaacagaa
     1801 agaacacatc catattgggg agatgaagca gacatcgcag atggcagcag agaatattgg
     1861 aagtgaatta ccacccagtg ccactcgatt taggctagat atgctgaaaa acaaagcaaa
     1921 gagatcttta acagagtctt tagaaagtat tttgtcccgg ggtaataaag ccagaggcct
     1981 gcaggaacac tccatcagtg tggatctgga tagctccctg tctagtacat taagtaacac
     2041 cagcaaagag ccatctgtgt gtgaaaagga ggccttgccc atctctgaga gctcctttaa
     2101 gctcctcggc tcctcggagg acctgtccag tgactcggag agtcatctcc cagaagagcc
     2161 agctccgctg tcgccccagc aggccttcag gaggcgagca aacaccctga gtcacttccc
     2221 catcgaatgc caggaacctc cacaacctgc ccgggggtcc ccgggggttt cgcaaaggaa
     2281 acttatgagg tatcactcag tgagcacaga gacgcctcat gaacgaaagg actttgaatc
     2341 caaagcaaac catcttggtg attctggtgg gactcctgtg aagacccgga ggcattcctg
     2401 gaggcagcag atattcctcc gagtagccac cccgcagaag gcgtgcgatt cttccagcag
     2461 atatgaagat tattcagagc tgggagagct tcccccacga tctcctttag aaccagtttg
     2521 tgaagatggg ccctttggcc ccccaccaga ggaaaagaaa aggacatctc gtgagctccg
     2581 agagctgtgg caaaaggcta ttcttcaaca gatactgctg cttagaatgg agaaggaaaa
     2641 tcagaagctc caagcctctg aaaatgattt gctgaacaag cgcctgaagc tcgattatga
     2701 agaaattact ccctgtctta aagaagtaac tacagtgtgg gaaaagatgc ttagcactcc
     2761 aggaagatca aaaattaagt ttgacatgga aaaaatgcac tcggctgttg ggcaaggtgt
     2821 gccacgtcat caccgaggtg aaatctggaa atttctagct gagcaattcc accttaaaca
     2881 ccagtttccc agcaaacagc agccaaagga tgtgccatac aaagaactct taaagcagct
     2941 gacttcccag cagcatgcga ttcttattga ccttgggcga acctttccta cacacccata
     3001 cttctctgcc cagcttggag caggacagct atcgctttac aacattttga aggcctactc
     3061 acttctagac caggaagtgg gatattgcca aggtctcagc tttgtagcag gcattttgct
     3121 tcttcatatg agtgaggaag aggcgtttaa aatgctcaag tttctgatgt ttgacatggg
     3181 gctgcggaaa cagtatcggc cagacatgat tattttacag atccagatgt accagctctc
     3241 gaggttgctt catgattacc acagagacct ctacaatcac ctggaggagc acgagatcgg
     3301 ccccagcctc tacgctgccc cctggttcct caccatgttt gcctcacagt tcccgctggg
     3361 attcgtagcc agagtctttg atatgatttt tcttcaggga acagaggtca tatttaaagt
     3421 ggctttaagt ctgttgggaa gccataagcc cttgattctg cagcatgaaa acctagaaac
     3481 catagttgac tttataaaaa gcacgctacc caaccttggc ttggtacaga tggaaaagac
     3541 catcaatcag gtatttgaaa tggacatcgc taaacagtta caagcttatg aagttgagta
     3601 ccacgtcctt caagaagaac ttatcgattc ctctcctctc agtgacaacc aaagaatgga
     3661 taaattagag aaaaccaaca gcagcttacg caaacagaac cttgacctcc ttgaacagtt
     3721 gcaggtggca aatggtagga tccaaagcct tgaggccacc attgagaagc tcctgagcag
     3781 tgagagcaag ctgaagcagg ccatgcttac cttagaactg gagcggtcgg ccctgctgca
     3841 gacggtggag gagctgcggc ggcggagcgc agagcccagc gaccgggagc ctgagtgcac
     3901 gcagcccgag cccacgggcg actgacagct ctgcaggaga gattgcaaca ccatcccaca
     3961 ctgtccaggc cttaactgag agggacagaa gacgctggaa ggagagaagg aagcgggaag
     4021 tgtgcttctc agggaggaaa ccggcttgcc agcaagtaga ttcttacgaa ctccaacttg
     4081 caattcaggg ggcatgtccc agtgtttttt ttgttgtttt tagatactaa atcgtccctt
     4141 ctccagtcct gattactgta cacagtagct ttagatggcg tggacgtgaa taaatgcaac
     4201 ttatgttttc ttgttggttc ctttttgagt gtcactgtgt ttgtaaagag cattcacaat
     4261 acggtggaat ttcaaaagct ggaagagctc gagatcatgc ctcaggcaaa ggcgtgggtc
     4321 catcgttctt ccgagagggt ttgtgtggcg actacaccct cagcgtccct ggcaaggtgc
     4381 agttggctct cgcccattct tgttatggaa acctaagatg atcattggga agatcagtga
     4441 tcttgggtca ttgatccctg gctcagagga tagcggtttc catcataaac caagatgatg
     4501 agttcagcct ttatccctcg tggttccact agatgtaact taaaggagtt aacatttgag
     4561 gactttgttc tacatcagat tttactattt gaatgtttaa gatcacttta ttgaatttga
     4621 agatcatcaa attaaataaa atgatttatt taatttggat atcctgatca ctgtcaagtg
     4681 aaatggatct ctctctttgg tatttaagga agtttgtctt taaaaaaaaa atagagtgtt
     4741 ttcatacatt tttgcttatc ccataagtac agttgatcaa agtcatagta ggtaaatgct
     4801 ttatgggaca gctgacacct tttagaccct accaggtatt gctagcatgt gagctgcagt
     4861 tgtggggtct gagatatttc tttgtggtag tttcataccc atactataga gtcatgtatt
     4921 tatttttgcc tgttgtgtga tgtaatgcaa tcatgttcct ttgagtctcc atcccttgga
     4981 aatctgactt cttgcagaag gagtaggcac atcaagatat tcaggggtgc cccaagagtc
     5041 tgggactttc aaaaaaaaaa gatcaggctg aaactgcagt cagatttatg acagctgaca
     5101 gtttttcaga ggtcgcacac agtgactctc ctctctcagg atgacgagga cctgtgcctt
     5161 caacaagcaa aatgctgctc acggttgtcc tgcttgcagc cagtcactgt gtaaagcctc
     5221 tctgatgtgc acttaagagt gggttgcttt ctcacaaaga tggggttctg tgcagtcaca
     5281 ggtcacttcc ttgacaacac aatcatttct gatctttatc actgtaacca cgtcttctat
     5341 tccataggag tttcttttga ttctctcagt tgcggggggc atctcttaat cctggggtaa
     5401 aaggagagat tgccatactt agactcactg tgagtctccc cggccatttc acgaggagac
     5461 cacagtgctg ccaccagtgc ctaaacaggt ggctggcatt cgagacttcc tcctgttccc
     5521 tgggtcagag gatagcggtt tccatcataa accaagatga tgagttcagc ctttatccct
     5581 cgtggttccg ctagatgtaa cttataggag ttaacatttg aggactttgt tctgcatcag
     5641 atcttactat ttgaatgttt actgttggat tttgggcatc ttattactgt tactcaaaaa
     5701 cattgactct gcatcaagaa agaaacaaga aagcaataaa acaagaaata attcatgctc
     5761 aca
//
