LOCUS       NM_001097643            1687 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens taste 2 receptor member 30 (TAS2R30), mRNA.
ACCESSION   NM_001097643 XM_001129113
VERSION     NM_001097643.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1687)
  AUTHORS   Meyerhof,W., Batram,C., Kuhn,C., Brockhoff,A., Chudoba,E., Bufe,B.,
            Appendino,G. and Behrens,M.
  TITLE     The molecular receptive ranges of human TAS2R bitter taste
            receptors
  JOURNAL   Chem Senses 35 (2), 157-170 (2010)
   PUBMED   20022913
REFERENCE   2  (bases 1 to 1687)
  AUTHORS   Go,Y., Satta,Y., Takenaka,O. and Takahata,N.
  TITLE     Lineage-specific loss of function of bitter taste receptor genes in
            humans and nonhuman primates
  JOURNAL   Genetics 170 (1), 313-326 (2005)
   PUBMED   15744053
REFERENCE   3  (bases 1 to 1687)
  AUTHORS   Fischer,A., Gilad,Y., Man,O. and Paabo,S.
  TITLE     Evolution of bitter taste receptors in humans and apes
  JOURNAL   Mol Biol Evol 22 (3), 432-436 (2005)
   PUBMED   15496549
  REMARK    Erratum:[Mol Biol Evol. 2005 Apr;22(4):1157]
REFERENCE   4  (bases 1 to 1687)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   5  (bases 1 to 1687)
  AUTHORS   Bufe,B., Hofmann,T., Krautwurst,D., Raguse,J.D. and Meyerhof,W.
  TITLE     The human TAS2R16 receptor mediates bitter taste in response to
            beta-glucopyranosides
  JOURNAL   Nat Genet 32 (3), 397-401 (2002)
   PUBMED   12379855
REFERENCE   6  (bases 1 to 1687)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   7  (bases 1 to 1687)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC018630.40.
            
            On Nov 11, 2021 this sequence version replaced NM_001097643.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000539585.1/ ENSP00000444736.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1687              AC018630.40        6044-7730
FEATURES             Location/Qualifiers
     source          1..1687
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.2"
     gene            1..1687
                     /gene="TAS2R30"
                     /gene_synonym="T2R30; T2R47; TAS2R47"
                     /note="taste 2 receptor member 30"
                     /db_xref="GeneID:259293"
                     /db_xref="HGNC:HGNC:19112"
                     /db_xref="MIM:613963"
     exon            1..1687
                     /gene="TAS2R30"
                     /gene_synonym="T2R30; T2R47; TAS2R47"
                     /inference="alignment:Splign:2.1.0"
     CDS             401..1360
                     /gene="TAS2R30"
                     /gene_synonym="T2R30; T2R47; TAS2R47"
                     /note="type 2 taste receptor member 47; type 2 taste
                     receptor member 30; taste receptor type 2 member 47; taste
                     receptor T2R47; taste receptor, type 2, member 30"
                     /codon_start=1
                     /product="taste receptor type 2 member 30"
                     /protein_id="NP_001091112.1"
                     /db_xref="CCDS:CCDS53750.1"
                     /db_xref="GeneID:259293"
                     /db_xref="HGNC:HGNC:19112"
                     /db_xref="MIM:613963"
                     /translation="MITFLPIIFSILIVVIFVIGNFANGFIALVNSIEWVKRQKISFV
                     DQILTALAVSRVGLLWVLLLHWYATQLNPAFYSVEVRITAYNVWAVTNHFSSWLATSL
                     SMFYLLRIANFSNLIFLRIKRRVKSVVLVILLGPLLFLVCHLFVINMDETVWTKEYEG
                     NVTWKIKLRSAMYHSNMTLTMLANFVPLTLTLISFLLLICSLCKHLKKMQLHGKGSQD
                     PSTKVHIKALQTVTSFLLLCAIYFLSMIISVCNFGRLEKQPVFMFCQAIIFSYPSTHP
                     FILILGNKKLKQIFLSVLRHVRYWVKDRSLRLHRFTRGALCVF"
ORIGIN      
        1 gtcgctaaag acaaatgatg gagaggttac acaaggaaaa attgcaaaca ctggaagtga
       61 acatgtcctt gtttgcatac tagcaaatga gaattcaggt ttcatgtcaa tttcagtatg
      121 aataattcca gcctataaca agaacagatg gtgaatgagt cagttaattt gaattgtttt
      181 gaaaataaga atgttttcca taaagagagc attgaactta tccattagca tgccatggtg
      241 atttctgact tgacactggt cacagcaatt aaaagtaaaa agaatgtcac agcacataca
      301 caaatcaggt gcatatagaa tttaaggtca ggatattcaa gcaatcacaa ccagtgatat
      361 tacaccagca ttttaaaaat ttctttttgt ctgttcagac atgataactt ttctgcccat
      421 cattttttcc attctaatag tggttatatt tgttattgga aattttgcta atggcttcat
      481 agcattggta aattccattg agtgggtcaa gagacaaaag atctcctttg ttgaccaaat
      541 tctcactgct ctggcggtct ccagagttgg tttgctctgg gtgttattac tacattggta
      601 tgcaactcag ttgaatccag ctttttatag tgtagaagta agaattactg cttataatgt
      661 ctgggcagta accaaccatt tcagcagctg gcttgctact agcctcagca tgttttattt
      721 gctcaggatt gccaatttct ccaaccttat ttttcttcgc ataaagagga gagttaagag
      781 tgttgttctg gtgatactgt tggggccttt gctatttttg gtttgtcatc tttttgtgat
      841 aaacatggat gagactgtat ggacaaaaga atatgaagga aacgtgactt ggaagatcaa
      901 attgaggagt gcaatgtacc attcaaatat gactctaacc atgctagcaa actttgtacc
      961 cctcactctg accctgatat cttttctgct gttaatctgt tctctgtgta aacatctcaa
     1021 gaagatgcag ctccatggca aaggatctca agatcccagc accaaggtcc acataaaagc
     1081 tttgcaaact gtgacctcct ttcttctgtt atgtgccatt tactttctgt ccatgatcat
     1141 atcagtttgt aattttggga ggctggaaaa gcaacctgtc ttcatgttct gccaagctat
     1201 tatattcagc tatccttcaa cccacccatt catcctgatt ttgggaaaca agaagctaaa
     1261 gcagattttt ctttcagttt tgcggcatgt gaggtactgg gtgaaagaca gaagccttcg
     1321 tctccataga ttcacaagag gggcattgtg tgtcttctag cagaaaacaa actggtggtg
     1381 tatgaaacat tttatatttc ttactgggtt ttctgtaata tatgtatatg aataatttcc
     1441 acatgtatac ctagaaaagt cttttaccta aagttagtct agaaaagtac atatatatag
     1501 atgtgtgtgt gtgtgtgtgt gtgtatgaaa aactgaagaa cattgacaat aacatgcttt
     1561 ttattgtttt ttcacaaaaa ctgccaaatt atagaaaata tgacaaaaat tcctcaatta
     1621 tgaagccatg tttatttcat acatgtattt tatatttcat ttgtagaatt tatatctatt
     1681 tataatt
//
