LOCUS       NM_024562               4893 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens transport and golgi organization 6 homolog (TANGO6),
            mRNA.
ACCESSION   NM_024562 XM_928235 XM_940431
VERSION     NM_024562.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4893)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009082.7, AB051533.1, AK095333.1 and BQ005531.1.
            
            On Nov 22, 2018 this sequence version replaced NM_024562.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.259030.1, AB051533.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000261778.2/ ENSP00000261778.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AC009082.7         116410-116484
            76-3275             AB051533.1         1-3200
            3276-3922           AK095333.1         2747-3393
            3923-4891           AB051533.1         3848-4816
            4892-4893           BQ005531.1         17-18               c
FEATURES             Location/Qualifiers
     source          1..4893
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.1"
     gene            1..4893
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /note="transport and golgi organization 6 homolog"
                     /db_xref="GeneID:79613"
                     /db_xref="HGNC:HGNC:25749"
                     /db_xref="MIM:620188"
     exon            1..181
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..3372
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /note="transmembrane and coiled-coil domain-containing
                     protein 7; transmembrane and coiled-coil domains 7"
                     /codon_start=1
                     /product="transport and Golgi organization protein 6
                     homolog"
                     /protein_id="NP_078838.1"
                     /db_xref="CCDS:CCDS45516.1"
                     /db_xref="GeneID:79613"
                     /db_xref="HGNC:HGNC:25749"
                     /db_xref="MIM:620188"
                     /translation="MAARQAVGSGAQETCGLDRILEALKLLLSPGGSGSSSLQVTKHD
                     VLLATLKSNLSALEDKFLKDPQWKNLKLLRDEIADKAEWPQNSVDVTWSFTSQTLLLL
                     LCLKETMIRLAANFNPGKPNPRTPEVAPALSPDALSISQQKTVQFVLQFVVTLGICPY
                     LMPGVGVPLRYRTEFGAVVQDVVCFDAAPDATRRLYTSCKALLNVAQHTSLGSLIFCH
                     HFGDIAAGLCQLGFCPTKRKLLTPAEEVLTEEERTLSRGALRDMLDQVYQPLAVRELL
                     ILQGGPPQSCTDVKTQMRCRAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGA
                     AGGSDAEVTAADWKKCDLIAKILASCPQQSLSPENYYRDICPQVLDLFHFQDKLTARQ
                     FQRVATTTFITLSRERPHLAAKYLLQPVLAPLHRCLNTAELSESDMVPGTILVTEEEL
                     SRCIEDVFKVYVVGNEPLTVLMDSLLPVLGVLFLLYCFTKQSVSHIRSLCQEILLWIL
                     GKLERKKAIASLKGFAGLDKAVPSLHSLCQFRVATQGGIMITIKEAISDEDEDEALYQ
                     KVSSEQGRVEHLGDLLSHCQECGLAGDFFIFCLKELTHVASENETELKTEPFSSKSLL
                     ELEQHQTLLVEGQERKLLVLQLMAVLCERMSEQIFTNVTQVVDFVAATLQRACASLAH
                     QAESTVESQTLSMSMGLVAVMLGGAVQLKSSDFAVLKQLLPLLEKVSNTYPDPVIQEL
                     AVDLRITISTHGAFATEAVSMAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQ
                     QSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAA
                     ALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKIL
                     PDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGA
                     HRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGL
                     SQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEK
                     KIMVLP"
     exon            182..822
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            823..939
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1081
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1218
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1381
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1464
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1577
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1754
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1887
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..2079
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2214
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2730
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            2731..2788
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            2789..2929
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..3081
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            3082..3195
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     exon            3196..4893
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3903..3908
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /note="hexamer: AATAAA"
     polyA_site      3925
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /note="major polyA site"
     regulatory      4861..4866
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
                     /note="hexamer: AATAAA"
     polyA_site      4893
                     /gene="TANGO6"
                     /gene_synonym="TMCO7"
ORIGIN      
        1 agagccttct gccacactta acatggcggc ggcggcgccc tgccgaggcg cctgagcggg
       61 tcgcgagcgt ggtgttacac tccagtcatg gcggcccgac aggccgtggg cagcggggct
      121 caggagacat gcggtctgga tcggattttg gaggcattga agctgctgct gagcccggga
      181 ggctcgggct caagttcact acaggtcaca aaacatgatg tcttgttggc tactttaaaa
      241 tctaacctgt ctgctttgga ggacaagttt ctgaaggatc ctcagtggaa gaatctgaaa
      301 ctcctaagag atgaaattgc tgataaggca gaatggccac aaaactctgt ggatgtcact
      361 tggagtttta cctctcaaac cttgttgttg cttttgtgct tgaaggaaac catgatccgc
      421 cttgcagcta atttcaatcc aggtaaaccc aaccctagga ctccggaagt tgctcctgcc
      481 ctgagccccg atgcacttag tatctcacaa cagaagactg tccagttcgt tttgcagttt
      541 gtagttacct tgggtatctg cccctatctc atgcctggtg ttggagtccc tttgagatat
      601 agaactgaat ttggtgccgt cgttcaagac gtggtgtgtt ttgatgctgc ccccgatgca
      661 actcgaagac tgtacaccag ctgcaaggcc cttctgaatg ttgctcagca cacatctctg
      721 gggagcttga tcttctgcca ccactttggg gatatcgcag caggtctgtg ccaactggga
      781 ttctgcccaa ccaaaagaaa actgctaaca cctgcagaag aggttctaac tgaagaggag
      841 agaaccctat ccaggggggc cttgagagac atgctggatc aagtctatca gcccttagca
      901 gtccgggaac tgcttatcct ccagggagga ccaccccagt cctgcacaga tgtgaagaca
      961 cagatgaggt gtcgggcccc agcttggctt cggcgtctat gtggacagct gctctctgaa
     1021 aggttaatga gacctaatgg tgttcaggca gtagtccggg gcattttgga aggagcaggt
     1081 gcgggagcag ctggtggaag tgatgctgag gtgacggctg ctgactggaa gaagtgtgac
     1141 ctgatcgcaa agattttggc ctcttgtccc cagcagtctc tttcaccaga gaattactac
     1201 agggacatct gcccccaggt tctggattta tttcactttc aagataaatt gacagcacga
     1261 caatttcaga gagttgccac cactaccttt ataactttgt caagagaacg cccacatttg
     1321 gcagcaaagt atttgctcca gccagtgtta gctcctcttc atcgatgttt gaatacagca
     1381 gagctttcag agagtgacat ggtaccagga actattttgg tgacagaaga agaacttagt
     1441 agatgcattg aggatgtgtt taaggtgtac gtggttggga atgaaccttt aacagttttg
     1501 atggattccc tgcttccagt cctgggagtg ctttttcttc tctactgttt tactaagcag
     1561 agtgtgtctc acataaggtc actttgccaa gaaatcttat tatggattct ggggaagctg
     1621 gaaaggaaga aggcaattgc cagcctgaaa ggatttgcag ggttggacaa agctgtgccc
     1681 tctctccatt ctctgtgtca gtttagagtt gccactcaag gtggcattat gattaccatc
     1741 aaagaggcca ttagtgatga agatgaagat gaagccctgt accagaaggt atcctctgag
     1801 cagggccggg tggagcatct cggggacttg ctgtcccact gccaggaatg cggtttggca
     1861 ggagacttct tcatcttctg tttgaaagag ttgactcatg tggcctcgga aaatgaaaca
     1921 gagttaaaaa ctgagccctt ctccagcaag agcctcttgg aattagagca acatcagact
     1981 cttcttgtgg aaggccaaga gcggaagctg cttgtcctgc agctgatggc tgttctgtgc
     2041 gagagaatgt ctgagcagat attcacaaac gtcactcagg tggtggactt tgtagcagca
     2101 acattgcaga gagcctgtgc aagcctggcc catcaggcag agagcaccgt ggaatcacag
     2161 acgctgagca tgtccatggg gctggtggct gtcatgctag gaggagctgt tcagttgaag
     2221 tcaagtgatt ttgctgttct gaagcagttg ttgcctctgt tggagaaggt atccaacaca
     2281 taccctgatc cggtcatcca agaactcgct gttgatctcc gcatcaccat ctctacccat
     2341 ggagcctttg ccactgaggc cgtcagcatg gctgcccaaa gtacactgaa cagaaaagat
     2401 ctggaaggga aaatagaaga gcagcaacaa accagtcatg aaagacccac tgatgtagct
     2461 catagccacc ttgaacaaca gcagagccat gagacagccc cccagacagg cctgcagtca
     2521 aatgctccaa tcattcctca aggagtcaat gagcccagca ctactacaag tcagaaatct
     2581 ggaagcgtaa ccacagaaca gctccaagag gttcttttgt cagcttatga ccctcaaatt
     2641 ccaacacggg ctgctgccct gcgtactctt tcccactgga tagagcagag agaagcaaaa
     2701 gcccttgaga tgcaagagaa gcttctcaag atattcttgg aaaacttgga acatgaagac
     2761 acttttgtat atctatctgc aattcagggg gttgccctgc tgtcagacgt ctatcctgag
     2821 aaaatcttgc cggacttgtt ggctcaatat gacagcagca aagacaagca cacaccagag
     2881 accagaatga aagtcgggga agtccttatg cgaatcgtca gggcattagg agacatggtc
     2941 tcaaagtacc gagaaccttt gatccatacc ttcctgaggg gagtgagaga tcctgatggt
     3001 gctcacaggg ccagcagctt ggccaacctt ggggagctgt gccagaggct ggactttctg
     3061 ctgggctccg tggtccatga ggtaacagct tgcctgattg ctgtggccaa aacagatggt
     3121 gaagttcaag tacgcagagc tgccatacat gtggttgtgc tgctgcttcg gggactcagc
     3181 cagaaagcta ctgaggtgct gagcgccgtc ctcaaggatc tctaccacct gctgaagcac
     3241 gtagtgtgtc tggagcccga tgacgtggcc aagctccatg cccagttggc cctagaagag
     3301 ctggatgaca tcatgaaaaa cttcctgttc cctccacaga agctggagaa gaagatcatg
     3361 gtcctgccgt agacctggct ccaaggacgt ggaggaggca ggcagggcca ggcacccaga
     3421 gccgtgccca ggtcttccag caggtggccc tgctgcctct tgagtgctgg cagcatggct
     3481 gaccctcggg gtggttttat ggtgcaggtc acttgggtct tcagggtccc ttccgagggc
     3541 atgtgttcag cactcccgcg ttcagcctga ggggtgtaca gttaagagaa gacagttaca
     3601 gatctcatta atctacattt ttcactgtcc tctagcattg aaagaaggat gtctacctgg
     3661 tgaaagtata ttttaacatg actgatggaa tttcactaat tgcccactct cttggaactt
     3721 gaggagaagc ggttggccac ccatatgtca cctagctcta tattctttca ggctgagatt
     3781 cttcttcagg aaaatgagga gcagaactgg ccacccttgg ctgctcaaga ggcatttcag
     3841 agtaggagat gcagttggag gtggggaggg gaaggaaata gttatcaaat aatgcaaaat
     3901 ggaataaagt tatcttggat ggaaagaaca gggctaaatc tggtcctctg gtgtcgagat
     3961 ggaaaactgt ggagttgaag aggctctgat gcccagaaag gacaatcaag ctggttgact
     4021 cttccagaga agaagggtaa gccctgtatt tatcctccca ggccattctt cttcactcct
     4081 gctgctgttt gcagagagtt gccctgatta tcaggagaaa agaaccacga gcatccagag
     4141 agtttacatc ctgccttctg tcctctgctc cttcagaaag atgaatgcct agacaatggg
     4201 ttcacactga atgcaggctg gaaagaatgc atgctggtgg cctaatgcca gggctgttga
     4261 aacaatttca gatatagcac tgtggtctcc actttatttc tttatatgtt ttggccgctg
     4321 cattttgatt gcagctaaaa gagataacag aaaggagata ctggctggct gcttcatatt
     4381 agccctctct gttgtcaaca ccttgatgag gccaacccag agatgcttga tcagtcctca
     4441 gctttgcagg gctaggtaca gaattttatc acaggatttt atcacgctct ctggggtgac
     4501 tagatccaca ggaaccaaaa cgcagtttcc aaaagctcga gtgactgaag gatctataca
     4561 caaacatggc tatttgctag ttaacaacag gatatttctc tctggccaga tcacagacat
     4621 ggttctgagt cagatcttcc ttggtggcat ccctttaaag aggccatctt atgaacagga
     4681 tcacaagtga gcttagtgag cagagagtta gaacaaatct agctaggtgt gtttaaggaa
     4741 tatttccatt cagctagtgt agctggatta atttctattc tccaaatcaa ggatgtctag
     4801 aaaatgggca ttgtggcttt caaatctaag aagaatctcc tttgggccag ctggatgtac
     4861 aataaaaatg cttgtttctt ggccttcctt taa
//
