LOCUS       XM_047446134            7052 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens tetratricopeptide repeat, ankyrin repeat
            and coiled-coil containing 1 (TANC1), transcript variant X30, mRNA.
ACCESSION   XM_047446134
VERSION     XM_047446134.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7052
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..7052
                     /gene="TANC1"
                     /gene_synonym="ROLSB; TANC"
                     /note="tetratricopeptide repeat, ankyrin repeat and
                     coiled-coil containing 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 32 ESTs, 857 long SRA reads, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 26 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:85461"
                     /db_xref="HGNC:HGNC:29364"
                     /db_xref="MIM:611397"
     CDS             159..5405
                     /gene="TANC1"
                     /gene_synonym="ROLSB; TANC"
                     /codon_start=1
                     /product="protein TANC1 isoform X29"
                     /protein_id="XP_047302090.1"
                     /db_xref="GeneID:85461"
                     /db_xref="HGNC:HGNC:29364"
                     /db_xref="MIM:611397"
                     /translation="MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSS
                     LPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPG
                     DAVIMPFREVAKPTEPDEHATITSSSENDDRSGSSLEWNKDGNLRLGVQKGVLHDRRA
                     DNCSPVAEEETTGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLED
                     LSYLDGQRNAPLRTSIRLPWHNTAGARFAPYKPQDILLKPLLFEVPSITTDSVFVGRD
                     WLFHQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGS
                     SPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAY
                     HYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVA
                     AFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPA
                     WLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNIS
                     LNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELY
                     LLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRM
                     DALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGK
                     LNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTP
                     NVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGM
                     TALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSP
                     GPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTA
                     AAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDK
                     QGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEG
                     AAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSV
                     VVALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALR
                     KFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYA
                     RARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLP
                     APLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNL
                     QEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRN
                     GSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNV
                     RLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGS
                     SGSPSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPF
                     MGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQ
                     AKTCSVSTLSASVHNGAQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHIS
                     NEAHRSHLTAAKPKRSFIESNV"
     polyA_site      7052
                     /gene="TANC1"
                     /gene_synonym="ROLSB; TANC"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ggctttgctg tggcagctgc tggagcggcg gccgcctcgg gagccggagg agaggcagcc
       61 gcggagcgcc gagctggcct cgccccgagg cccggccctg ggtgtgggga accgcgctga
      121 ggagctggaa actttcccgg cagaaacaag tgttgaaaat gttaaaggct gtgctgaaga
      181 agagccgaga gggaggaaag ggaggcaaga aggaagcagg aagtgacttt ggtccagaga
      241 cttctccagt cctgcacctt gaccacagtg ctgactctcc tgtgagcagt cttcccacag
      301 cagaggacac ctatagggtg agcttggcca aaggtgtctc gatgtctctg ccttcctcac
      361 ctttgctgcc tcgacagtct cacttggtgc aatcaagagt gaacaaaaaa tccccaggtc
      421 ccgtcaggaa gcccaagtat gtggaaagcc ccagagtgcc tggagatgca gttataatgc
      481 cattcagaga agtagccaag ccaacagagc ctgatgagca tgccacaatt acaagttcat
      541 ccgaaaatga tgaccggagt ggctccagtt tggaatggaa taaagatgga aacctaagat
      601 taggggttca gaagggagtg cttcatgacc gcagggcaga taactgctcc ccagtggcag
      661 aagaggagac caccgggtca gcagagagca cgctgcccaa agcagaatcc tcagctggag
      721 atggtccagt cccttattct cagggctcca gctcactaat aatgccacgg cccaactcag
      781 ttgcagcaac aagctcaacc aaattggaag atctgagtta tttagacggg cagagaaatg
      841 ctcctctacg gacgtcaatt agattaccat ggcacaatac ggccggagca cgatttgctc
      901 cctacaagcc acaagacatt ttgttgaaac ccttgttgtt tgaagtacca agcataacaa
      961 cagactctgt gtttgtggga agggattggc tctttcacca gatagaagaa aacttgagga
     1021 acacagaact ggcagaaaac agaggcgcgg tggtggttgg caatgtggga tttgggaaga
     1081 cggcaatcat ttccaagttg gtggccctga gctgccacgg aagccgcatg aggcagattg
     1141 cttccaacag cccgggttca tcacctaaaa cctctgaccc cactcaggat cttcatttca
     1201 ctccgttgct ttcaccgagt tcttccacaa gtgcttccag cacagctaaa acacctcttg
     1261 ggtctatcag tgctgaaaac cagagaccaa gagaggatgc agtgaaatat cttgcttcta
     1321 aggtggtggc ctaccactac tgccaggctg acaacacgta cacttgcctg gtgcccgagt
     1381 ttgtgcacag catcgcagct ttgctctgcc ggtcccatca gctggccgcc tacagagacc
     1441 ttctgataaa ggagccccaa ctacagagca tgctgagcct ccgatcctgt gtgcaggacc
     1501 cggtggcagc tttcaagagg ggagtgctgg agccactcac aaacctgaga aatgagcaga
     1561 aaattcctga agaagaatac attattttga tagatggctt aaatgaagct gagtttcata
     1621 aacctgatta tggagatacg ctttcttcat ttattaccaa aattatttct aaatttcctg
     1681 cctggttgaa gttgattgtg actgtaagag caaattttca ggaaatcata agtgcgctgc
     1741 catttgtcaa gctttcctta gatgacttcc cagacaacaa agacatccac agtgacctgc
     1801 acgcctacgt ccagcacagg gtgcacagca gccaggacat cctcagcaac atctccctga
     1861 atggcaaggc cgatgccaca ctcattggaa aagtgagcag ccacctggtg ctgcggagcc
     1921 tcggctccta cctgtacctc aagctcaccc tggacctttt ccagaggggc cacttggtca
     1981 ttaagagtgc cagctacaag gtggtgcccg tgtctctctc tgagctctat ttgcttcagt
     2041 gcaacatgaa gttcatgacc cagtccgcct ttgagagggc acttccgatt ctcaacgtgg
     2101 ccctcgcatc cctccacccc atgacagacg agcagatctt tcaggctatt aatgctggcc
     2161 acatccaggg ggagcaggga tgggaagact ttcagcagag gatggacgcc ctctcctgct
     2221 tcctcattaa gaggcgagac aaaacccgca tgttctgcca cccgtccttc agggagtggc
     2281 ttgtatggag agcagacggg gaaaacacgg ccttcctgtg tgagcccagg aacgggcacg
     2341 cgctcttggc attcatgttc tcgcgtcagg agggcaagtt gaaccgccag cagaccatgg
     2401 agcttggcca ccacatcctg aaggcgcaca ttttcaaggg cctcagtaag aagacgggaa
     2461 tttcttcaag ccatctccaa gccctgtgga tcggctacag caccgagggg ctgtccgccg
     2521 ccctggcctc tctcaggaat ctctatactc ccaacgtgaa ggtgagccgt ctcctgattt
     2581 tgggaggggc caacgtgaac tacaggacag aagtgttaaa taatgcccca atcctgtgcg
     2641 tccagtctca ccttggccac gaggaagttg tcactctgct cctggaattt ggtgcctgcc
     2701 tggacggaac gtcagagaac ggcatgactg ccctctgtta cgcagcagct gctggccaca
     2761 tgaagctggt gtgtctgctg accaagaagg gagtgagagt ggaccacttg gataagaagg
     2821 gccagtgtgc gcttgtccac agtgccctac ggggccacgg tgacattctc cagtacctgc
     2881 tgacttgtga gtggtcgccg ggtcctcccc agccaggcac cctgaggaag agccacgccc
     2941 tgcagcaggc gctgaccgcg gcggccagca tgggccacag ctcggtggtc cagtgcttgc
     3001 tggggatgga gaaggaacat gaagtagaag tcaatggcac cgacacattg tggggagaaa
     3061 cagccctgac tgccgccgca ggaagaggga agctggaggt ctgtgagctg ctgctggggc
     3121 atggagctgc tgtgtcgcgg acaaacagga gaggggttcc acctttgttt tgtgcagcac
     3181 gccaggggca ttggcagatt gttagactgc tgttggaacg cggctgtgat gtgaacctaa
     3241 gtgacaagca aggccggacg cccctcatgg tggctgcttg tgaagggcac ttgagcaccg
     3301 tggaattcct cctttcaaaa ggtgcagccc tttcttctct agacaaagag ggtctgtcag
     3361 cattaagctg ggcttgtctg aaaggtcaca gggcagtggt ccagtatctg gttgaagaag
     3421 gagctgcaat agaccagaca gacaagaatg gccgcacacc cttggacctg gctgccttct
     3481 atggcgatgc cgagactgtg ctgtacctgg tggagaaggg agccgtgatc gagcatgtgg
     3541 accacagcgg gatgcggccc ttggacagag ccatcggctg ccggaacaca tctgtagtgg
     3601 tggcgctact cagaaaggga gccaagttag gaaatgctgc ttgggcgatg gccacttcca
     3661 aacctgatat cttgattata cttttacaga aattaatgga ggaaggaaat gtgatgtaca
     3721 aaaaagggaa aatgaaagag gcagcccaga ggtaccagta tgccttaaga aagtttcctc
     3781 gagaaggatt cggagaggac atgagaccct tcaatgaatt aagggtttcc ctctatctca
     3841 atttgtcgcg atgccgaaga aaaacaaatg actttggcat ggcagaggaa tttgcttcca
     3901 aggctctcga attgaagccc aagtcctatg aagcctttta tgccagagca agagcgaaga
     3961 gaaatagcag gcaattcgtg gcagctctgg ctgacctgca agaggctgtg aaactctgtc
     4021 ccaccaatca ggaagtcaag aggcttctgg cccgcgtaga agaggagtgc aaacaactcc
     4081 agaggagtca acagcaaaaa cagcagggcc cgctaccagc tccactcaac gactccgaga
     4141 acgaagagga caccccaacc cctggcttaa gtgaccactt tcactctgag gagactgaag
     4201 aggaagaaac ttctccccag gaagaatctg tttccccaac tcccaggtcc cagccatcct
     4261 catctgtccc ttcctcatac atccgaaacc ttcaagaagg gttacagtcc aaaggaaggc
     4321 cggtatcgcc acagagcagg gcaggaatcg gcaagtccct gagagagcct gtggcccagc
     4381 cagggctgct cctgcagccc tccaagcagg cccagatcgt gaaaaccagc cagcacctgg
     4441 gctctggcca gtcggcagtg agaaatggca gtatgaaagt tcagatctct tctcagaacc
     4501 ctcctccaag tcccatgcca gggagaatcg ctgccactcc tgctgggagc agaacccagc
     4561 atttagaggg aacaggtact ttcactacaa gagctggttg tggccacttt ggggatcggc
     4621 tgggccccag ccagaatgtc cgcctgcagt gtggtgagaa tggccctgca caccctttac
     4681 caagtaagac gaaaaccaca gagaggcttc tgtctcattc ctccgtggct gtggacgcag
     4741 cccctccaaa ccaaggtggg ctggcgacct gcagcgacgt gcgacaccca gcttccctca
     4801 ccagctcagg ctcttctggt tctccatcca gcagcataaa gatgtcaagt tcaaccagta
     4861 gtttgacttc gagcagcagt ttttcagatg gcttcaaggt ccaaggacca gatactagaa
     4921 ttaaagacaa ggttgtaacc cacgttcaga gcggtacagc tgagcacaga ccccgcaaca
     4981 cgccgttcat gggcatcatg gataagactg cgaggttcca acagcagagc aatcctccaa
     5041 gccgcagctg gcactgtccg gcaccagagg ggctgctgac aaacacgtct tctgcagctg
     5101 gcctgcagtc tgctaacact gagaagccct ctctcatgca agtgggagga tataataacc
     5161 aagccaaaac ctgttctgtt tctaccctga gtgcaagtgt ccacaatggg gcacaagtga
     5221 aggagctaga agaaagcaag tgccaaattc cagtccactc tcaagagaac aggataacta
     5281 agactgtttc tcatctgtac caggaaagta tctccaaaca gcagcctcat attagtaatg
     5341 aagcccacag gagccacctc actgcagcca aaccaaagcg atcatttata gagtcaaatg
     5401 tgtgaacctt aagaaatccc catttgtgga atttggaaac gtgtgttgac tcctggtggt
     5461 aaattaaata gtttttttca tcagaaaaat tattttttag ccattttttt tctttggggt
     5521 ggatctgatg ccattgatat atctaaaatg tgggataaaa cttctttaat agctagaaat
     5581 caccataaat aagaatgcta aacagaattg aaaattatat caacttaaaa ttttaagaca
     5641 gcccagaaga cattaatgac tctcacttat gaaattgttt ggcttttgcc actttcttcc
     5701 ttgcctttgc tatatggtag aatcacagaa cttacttaga gaataaatat gtctattgtt
     5761 caagagtaac aggtttaact catgaccaag tgatgtacat ccaagtgatg tattctggaa
     5821 acgatggaat tttacagtta cagttccatt gagtcaaatc ccattttata tatacataaa
     5881 aattaagttc tgagtgagtt ctagctaaat ataagtgcga ctgtaaacgc agccaatttt
     5941 tttaagcaga atatgagaac acctaagtat tctcttcata gcagttccta taaagggatt
     6001 aaacacttat ttctgtgtta tggttcttat tcatatattt ttatagcact tttggaacct
     6061 atatttgtgc ttgaaggtgt ttttgatatt tggaaacagt ataagccatt tggagtcatg
     6121 attggtggtc aagtggattc aagctaaaat actaagacca gcattcttag tggcgcttat
     6181 aaattagctc tcacctggtt tccaaactgc ttttaacaat ggtagtgctc ctggaacaat
     6241 ccttccaagc tcctctaagg acaatattta attcagatac taaaggtaag actggttgtt
     6301 acttttgttt tgttgtacaa ttagtacttt atagtcacat gttgtatata ttaaatagcc
     6361 cagttttatt cagacttgta aatagaacta tttcaatgta gttaatctaa aaacaaaaaa
     6421 gaaaacccca gtcacgattt gcatgttctc tgtaagcttc atccatgctg gttattgcac
     6481 tgaatgatat attattaggg catgttaaca gtataccagt aacagcactt tatctcattt
     6541 atatgaacac ctttgaggtg ctacttaagt ccaagctctg atgtattatt catttgtaaa
     6601 gataaggtac aggaatgaac cttggtttaa aggtattttt atatgaaaat ggtgtgttat
     6661 tggaagatgt taaaatgcta atttgagaga agtaggagtg tatctgtttt atatgttggg
     6721 atgtgaaatt tattttctaa aattgaggag aaggaagtta tatatttgca gaatgtttta
     6781 aagtgaattg ttgtaatgaa gttcctgtga acatcattat ggttttgtac aaataggaac
     6841 ctctgatgtc attcttcaac gtttgttcct gtgtgtacaa ttgtactttg tatgaacagc
     6901 tttatcattt ttataggctt tccatgagtt ttgctgtaac tactatggct tatttatttt
     6961 ctttaatatt tgtgaaagtc ttactccttt gttagttttg tttctgcaca actactgtac
     7021 ttttccatat ggaataaaga ctattaatag aa
//
