LOCUS       XM_047422139            7645 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transforming acidic coiled-coil containing
            protein 1 (TACC1), transcript variant X2, mRNA.
ACCESSION   XM_047422139
VERSION     XM_047422139.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7645
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..7645
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /note="transforming acidic coiled-coil containing protein
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 50 ESTs, 3471 long SRA reads, 10
                     Proteins, and 98% coverage of the annotated genomic
                     feature by RNAseq alignments"
                     /db_xref="GeneID:6867"
                     /db_xref="HGNC:HGNC:11522"
                     /db_xref="MIM:605301"
     CDS             223..2640
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /codon_start=1
                     /product="transforming acidic coiled-coil-containing
                     protein 1 isoform X2"
                     /protein_id="XP_047278095.1"
                     /db_xref="GeneID:6867"
                     /db_xref="HGNC:HGNC:11522"
                     /db_xref="MIM:605301"
                     /translation="MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDS
                     QAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLV
                     AEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDST
                     DISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNS
                     CPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTS
                     PLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEAR
                     KALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESP
                     SFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNE
                     ILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEK
                     LASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEED
                     GSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEW
                     KKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN
                     SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK
                     LDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELI
                     AKLGKTD"
ORIGIN      
        1 gcacagccgc ccgccgccca gcacaggagg gtgcagcccc ggccccaagt tctgcgccat
       61 gggaggctcc cactctcaga ccccgagggg ccgggaaccc gccggggaga ggcacccgag
      121 acccacggag accgcaaaca gaaccctgtg tcaaatccag gagcctgggg gactgtagaa
      181 cctgaagttt tactgggagc tggagccgga ggagccgcgc tcatggcgtt cagcccgtgg
      241 cagatcctgt cccccgtgca gtgggcgaaa tggacgtggt ctgcggtacg cggcggggcc
      301 gccggcgagg acgaggctgg cgggcccgag ggcgaccccg aggaggagga ttcgcaagcc
      361 gagaccaaat ccttgagttt cagctcggat tctgaaggta attttgagac tcctgaagct
      421 gaaaccccga tccgatcacc tttcaaggag tcctgtgatc catcactcgg attggcagga
      481 cctggggcca aaagccaaga atcacaagaa gctgatgaac agcttgtagc agaagtggtt
      541 gaaaaatgtt catctaagac ttgttctaaa ccttcagaaa atgaagtgcc acagcaggcc
      601 attgactctc actcagtcaa gaatttcaga gaagaacctg aacatgattt tagcaaaatt
      661 tccatcgtga ggccattttc aatagaaacg aaggattcca cggatatctc ggcagtcctc
      721 ggaacaaaag cagctcatgg ctgtgtaact gcagtctcag gcaaggctct gccttccagc
      781 ccgccagacg ccctccagga cgaggcgatg acagaaggca gcatgggggt caccctcgag
      841 gcctccgcag aagctgatct aaaagctggc aactcctgtc cagagcttgt gcccagcaga
      901 agaagcaagc tgagaaagcc caagcctgtc cccctgagga agaaagcaat tggaggagag
      961 ttctcagaca ccaacgctgc tgtggagggc acacctctcc ccaaggcatc ctatcacttc
     1021 agtcctgaag agttggatga gaacacaagt cctttgctag gagatgccag gttccagaag
     1081 tctccccctg accttaaaga aactcccggc actctcagta gtgacaccaa cgactcaggg
     1141 gttgagctgg gggaggagtc gaggagctca cctctcaagc ttgagtttga tttcacagaa
     1201 gatacaggaa acatagaggc caggaaagcc cttccaagga agcttggcag gaaactgggt
     1261 agcacactga ctcccaagat acaaaaagat ggcatcagta agtcagcagg tttagaacag
     1321 cctacagacc cagtggcacg agacgggcct ctctcccaaa catcttccaa gccagatcct
     1381 agtcagtggg aaagccccag cttcaacccc tttgggagcc actctgttct gcagaactcc
     1441 ccacccctct cttctgaggg ctcctaccac tttgacccag ataactttga cgaatccatg
     1501 gatcccttta aaccaactac gaccttaaca agcagtgact tttgttctcc cactggtaat
     1561 cacgttaatg aaatcttaga atcacccaag aaggcaaagt cgcgtttaat aacgagtggc
     1621 tgtaaggtga agaagcatga aactcagtct ctcgccctgg atgcatgttc tcgggatgaa
     1681 ggggcagtga tctcccagat ttcagacatt tctaataggg atggccatgc tactgatgag
     1741 gagaaactgg catccacgtc atgtggtcag aaatcagctg gtgccgaggt gaaaggtgag
     1801 ccagaggaag acctggagta ctttgaatgt tccaatgttc ctgtgtctac cataaatcat
     1861 gcgttttcat cctcagaagc aggcatagag aaggagacgt gccagaagat ggaagaagac
     1921 gggtccactg tgcttgggct gctggagtcc tctgcagaga aggcccctgt gtcggtgtcc
     1981 tgtggaggtg agagccccct ggatgggatc tgcctcagcg aatcagacaa gacagccgtg
     2041 ctcaccttaa taagagaaga gataattact aaagagattg aagcaaatga atggaagaag
     2101 aaatacgaag agacccggca agaagttttg gagatgagga aaattgtagc tgaatatgaa
     2161 aagactattg ctcaaatgat tgaagatgaa caaaggacaa gtatgacctc tcagaagagc
     2221 ttccagcaac tgaccatgga gaaggaacag gccctggctg accttaactc tgtggaaagg
     2281 tccctttctg atctcttcag gagatatgag aacctgaaag gtgttctgga agggttcaag
     2341 aagaatgaag aagccttgaa gaaatgtgct caggattact tagccagagt taaacaagag
     2401 gagcagcgat accaggccct gaaaatccac gcagaagaga aactggacaa agccaatgaa
     2461 gagattgctc aggttcgaac aaaagcaaag gctgagagtg cagctctcca tgctggactc
     2521 cgcaaagagc agatgaaggt ggagtccctg gaaagggccc tgcagcagaa gaaccaagaa
     2581 attgaagaac tgacaaaaat ctgtgatgag ctgattgcaa agctgggaaa gactgactga
     2641 gacactcccc ctgttagctc aacagatctg catttggctg cttctcttgt gaccacaatt
     2701 atcttgcctt atccaggaat aattgcccct ttgcagagaa aaaaaaaaac ttaaaaaaag
     2761 cacatgccta ctgctgcctg tcccgctttg ctgccaatgc aacagccctg gaagaaaccc
     2821 tagagggttg catagtctag aaaggagtgt gacctgacag tgctggagcc tcctagtttc
     2881 cccctatgaa ggttccctta ggctgctgag tttgggtttg tgatttatct ttagtttgtt
     2941 ttaaagtcat ctttactttc ccaaatgtgt taaatttgta actcctcttt ggggtcttct
     3001 ccaccacctg tctgattttt ttgtgatctg tttaatcttt taatttttta gtatcagtgg
     3061 ttttatttaa ggagacagtt tggcctattg ttacttccaa tttataatca agaaggggct
     3121 ctggatcccc ttttaaatta cacacactct cacacacata catgtatgtt tatagatgct
     3181 gctgctcttt tccctgaagc atagtcaagt aagaactgct ctacagaagg acatatttcc
     3241 ttggatgtga gaccctattt tgaaatagag tcctgactca gaacaccaac ttaagaattt
     3301 gggggattaa agatgtgaag accacagtct tgggttttca tatctggaga agactatttg
     3361 ccatgacgtt ttgttgccct ggtatttgga cactcctcag ctttaatggg tgtggcccct
     3421 ttagggttag tcctcagact aatgatagtg tctgctttct gcatgaacgg caatatggga
     3481 ctccctccaa gctagggttt ggcaagtctg ccctagagtc atttactctc ctctgcctcc
     3541 atttgttaat acagaatcaa catttagtct tcattatctt tttttttttt tttgagacag
     3601 agtttcgatc tattttaagt atgtgaagaa aatctacttg taaaaggctc agatcttaat
     3661 taaaaggtaa ttgtagcaca ttaccaatta taaggtgaag aaatgttttt ttcccaagtg
     3721 tgatgcattg ttcttcagat gttgaaaaga aagcaaaaaa taccttctaa cttaagacag
     3781 aatttttaac aaaatgagca gtaaaagtca catgaaccac tccaaaaatc agtgcatttt
     3841 gcatattttt aaacaaagac agcttgttga atactgagaa gaggagtgca aggagaaggt
     3901 ctgtactaac aaagccaaat tcctcaagct cttactggac tcagttcaga gtggtgggcc
     3961 attaacccca acatggaatt tttccatata aatctcaatg aattcccttt catttgaata
     4021 ggcaaaccca aatccatgca agtgttttaa agcactgtcc tgtcttaatc ttacatgctg
     4081 aaagtcttca tggtgatatg cactatattc agtatacgta tgttttccta cttctcttgt
     4141 aaaactgttg catgatccaa cttcagcaat gaattgtgcc tagtggagaa cctctataga
     4201 tcttaaaaaa tgaattattc tttagcagtg tattactcac atgggtgcaa tctttagccc
     4261 cagggaggtc aataatgtct tttaaagcca gaagtcacat tttaccaata tgcatttatc
     4321 ataattggtg cttaggctgt atattcaagc ctgttgtctt aacattttgt ataaaaaaga
     4381 acaacagaaa ttatctgtca tttgagaagt ggcttgacaa tcatttgagc tttgaaagca
     4441 gtcactgtgg tgtaatatga atgctgtcct agtggtcata gtaccaaggg cacgtgtctc
     4501 cccttggtat aactgatttc ctttttagtc ctctactgct aaataagtta attttgcatt
     4561 ttgcagaaag aaacattgat tgctaaatct ttttgctgct gtgttttggt gttttcatgt
     4621 ttacttgttt tatattgatc tgttttaagt atgagaggct tatagtgccc tccattgtaa
     4681 atccatagtc atctttttaa gcttattgtg tttaagaaag tagctatgtg ttaaacagag
     4741 gtgatggcag cccttcccta gcacactggt ggaagagacc ccttaagaac ctgaccccag
     4801 tgaatgaagc tgatgcacag ggagcaccaa aggaccttcg ttaagtgata attgtcctgg
     4861 cctctcagcc atgaccgtta tgaggaaata tcccccattc gaacttaaca gatgcctcct
     4921 ctccaaagag aattaaaatc gtagcttgta cagatcaaga gaatatactg ggcagaatga
     4981 agtatgtttg tttatttttc tttaaaaata aaggattttg gaactctgga gagtaagaat
     5041 atagtataga gtttgcctca acacatgtga gggccaaata acctgctagc taggcagtaa
     5101 taaactctgt tacagaagag aaaaagggcc gggcacagtg gcttattcct gtaatcccaa
     5161 cactgtggaa ggccgaggca ggaggatcac ttgagtccag gagtttgaaa cctacctagg
     5221 caacatggtg aaaccttgtc tctaccaaaa taaaaattag ctgggcatgg tggcacgtgc
     5281 ctgtggtccc agctacttgg gaggctgagg tgggagcctg ggaggtcaag gctgcagtga
     5341 gccatgatca tgccactgca ctccatcctg ggtgacagca agatcttgtc tcaaaaaaaa
     5401 aaaaaaaaaa aaaaaaacca ggagtgaaaa aggaaagtag aaggcagctg ctggcctaga
     5461 tgttggtttg ggaatattag gtgatcctgt tgagattctg gatccagagc aatttcttta
     5521 gcttttgact ttgccaaagt gtagatagcc tttatccagc agtattttaa gtggggaatg
     5581 caacgtgagg ccaactgaac aattcccccc gtggctgccc agatagtcac agtcaaggtt
     5641 ggagagtctc cttccagcca gtgacctacc caaacctttt gttctgtaaa actgctctgg
     5701 aaataccggg aagcccagtt ttctcacgtg gtttctagct tcttcagact cagcccaaat
     5761 taggaagtgc agaagcacat gatggtgaaa aacctaggat ttggcagcct tccagaatgg
     5821 tatggaatct gagggaagat ttatgtttcg ttttggagga tagctcaagt tgaattttct
     5881 ttccagccag ttaccctttc aacctaccca tactttgtac aactcttaca caaatactta
     5941 gatatttatt agatagccct gaattcactc taattataaa cagggagtgt aaactgcccc
     6001 cagatgttcc tgggctgggt aaaagcagct ggagtgaagc actcattttc cataaaggta
     6061 acaaagggca gctcagtggt tactcaagct caaaagggtt tttttaagag caagcattgg
     6121 ttaagtctgt gtatactgag ttggaagtga tttcagcaca ttctttttta gtggagtgaa
     6181 agttctgaag ccccctttta acttcctctt ggtttttcat tataattggt agccatctca
     6241 tgaactgtct ctgactgttg tctctttgtg gtcatgtgat tgtgagcttg ctttctgact
     6301 tgcatttctg actttatcct gttgttagga agatagaaac taggttttga aagattacat
     6361 gattcaagcg agggatttta aagtaaagat gtatttattc tgaagaatct aaaagataac
     6421 agattatttg cttatgaaag aacaatatag tctgggaatc ccagaatgtc aagccaaagg
     6481 tctaagaagt catctccttc aaatacttta ataaagaagt atttcgagga gatatctgtc
     6541 caaaaaggtt tgactggcct ccagattcca gttattttta aaaagcaact taccactaaa
     6601 tccttgagtc tccatagagt aacagtaaag aaactgatgt aacagactct cctctcaaag
     6661 gatctcctct ggaagagact atcagcggca gcattctcca gggaagaccc atcccctagt
     6721 gccagagctt gcatcctgga gactaaagat tgcacttttt tgtagttttt tgtccaaatg
     6781 caatcccatt tctgtgcctc ttagcatgca gttagatttg gacaaacaag attcctaagg
     6841 aatgacttta ttaactataa tatggttaca gctattatat aaatatatat tctggttata
     6901 gttctaatat ggagatgttg tgtgcaatgc tggcctgtgg tggtctgtgt aatgctttaa
     6961 cttgtatgga ggaggccagg ctcagagctg agatgtggcc tgaaccttcc ctgtatcgat
     7021 cctttaattt agaactgtca agatgtcact ttctccccct ctgcctttta gtggtatctg
     7081 acatatactc aaaacagtaa tttcctggtc acatcattaa ctgctaattc tgtatttata
     7141 aagaattttc agatggacat gtacaaattt gaactcaaac catccccagt ccagatacag
     7201 ggcagcgtgt aggtgaccac accagagcct cagcctcggt ccttctcagc cgtcgggata
     7261 ggatccaggc atttctttta aatctcagag gtagcagtaa acttttcagt attgctgtta
     7321 gcaagtgtgt gtttgccaat agatacccat tatactaatg tgccaagtaa atgttcattg
     7381 cacatctgct tccactgtgt tcccacgggt gccatgaagt gtgtgaggag cccctcatct
     7441 ggagggatga gtgctgcgtt gactactgct atcaggattg tgttgtgtgg aatattcatc
     7501 tacataaatt ttatatgcac agtaatttcc ctttttatat gtcaagtaac tatttgtaaa
     7561 agttatactc acaaattatt ataatgatta ctaatatatt ttttccatgt ttcattgcct
     7621 gaataaaaac tgtttaccac tgtta
//
