LOCUS       NM_001352782            7397 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens transforming acidic coiled-coil containing protein 1
            (TACC1), transcript variant 9, mRNA.
ACCESSION   NM_001352782 XM_017013766
VERSION     NM_001352782.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7397)
  AUTHORS   Wang,Y., Li,M., Zhang,L., Chen,Y. and Ha,M.
  TITLE     LINC01140 inhibits nonsmall cell lung cancer progression and
            cisplatin resistance through the miR-4742-5p/TACC1 axis
  JOURNAL   J Biochem Mol Toxicol 36 (7), e23048 (2022)
   PUBMED   35307914
  REMARK    GeneRIF: LINC01140 inhibits nonsmall cell lung cancer progression
            and cisplatin resistance through the miR-4742-5p/TACC1 axis.
REFERENCE   2  (bases 1 to 7397)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 7397)
  AUTHORS   Devereaux,K.A., Weiel,J.J., Mills,A.M., Kunder,C.A. and
            Longacre,T.A.
  TITLE     Neurofibrosarcoma Revisited: An Institutional Case Series of
            Uterine Sarcomas Harboring Kinase-related Fusions With Report of a
            Novel FGFR1-TACC1 Fusion
  JOURNAL   Am J Surg Pathol 45 (5), 638-652 (2021)
   PUBMED   33481389
  REMARK    GeneRIF: Neurofibrosarcoma Revisited: An Institutional Case Series
            of Uterine Sarcomas Harboring Kinase-related Fusions With Report of
            a Novel FGFR1-TACC1 Fusion.
REFERENCE   4  (bases 1 to 7397)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   5  (bases 1 to 7397)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 7397)
  AUTHORS   Line,A., Stengrevics,A., Slucka,Z., Li,G., Jankevics,E. and
            Rees,R.C.
  TITLE     Serological identification and expression analysis of gastric
            cancer-associated genes
  JOURNAL   Br J Cancer 86 (11), 1824-1830 (2002)
   PUBMED   12087473
REFERENCE   7  (bases 1 to 7397)
  AUTHORS   Lauffart,B., Howell,S.J., Tasch,J.E., Cowell,J.K. and Still,I.H.
  TITLE     Interaction of the transforming acidic coiled-coil 1 (TACC1)
            protein with ch-TOG and GAS41/NuBI1 suggests multiple
            TACC1-containing protein complexes in human cells
  JOURNAL   Biochem J 363 (Pt 1), 195-200 (2002)
   PUBMED   11903063
  REMARK    GeneRIF: Interaction of the transforming acidic coiled-coil 1
            (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple
            TACC1-containing protein complexes in human cells
REFERENCE   8  (bases 1 to 7397)
  AUTHORS   Gergely,F., Karlsson,C., Still,I., Cowell,J., Kilmartin,J. and
            Raff,J.W.
  TITLE     The TACC domain identifies a family of centrosomal proteins that
            can interact with microtubules
  JOURNAL   Proc Natl Acad Sci U S A 97 (26), 14352-14357 (2000)
   PUBMED   11121038
REFERENCE   9  (bases 1 to 7397)
  AUTHORS   Still,I.H., Hamilton,M., Vince,P., Wolfman,A. and Cowell,J.K.
  TITLE     Cloning of TACC1, an embryonically expressed, potentially
            transforming coiled coil containing gene, from the 8p11 breast
            cancer amplicon
  JOURNAL   Oncogene 18 (27), 4032-4038 (1999)
   PUBMED   10435627
REFERENCE   10 (bases 1 to 7397)
  AUTHORS   Still,I.H., Vince,P. and Cowell,J.K.
  TITLE     The third member of the transforming acidic coiled coil-containing
            gene family, TACC3, maps in 4p16, close to translocation
            breakpoints in multiple myeloma, and is upregulated in various
            cancer cell lines
  JOURNAL   Genomics 58 (2), 165-170 (1999)
   PUBMED   10366448
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC016813.20 and AC067817.10.
            
            On May 31, 2019 this sequence version replaced NM_001352782.1.
            
            Summary: This locus may represent a breast cancer candidate gene.
            It is located close to FGFR1 on a region of chromosome 8 that is
            amplified in some breast cancers. Several transcript variants
            encoding different isoforms have been found for this gene.
            [provided by RefSeq, Jun 2017].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.246228.1,
                                           SRR1660805.251576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               AC016813.20        11605-11739         c
            136-251             AC067817.10        43060-43175
            252-1365            AC067817.10        73878-74991
            1366-1426           AC067817.10        79664-79724
            1427-1634           AC067817.10        81524-81731
            1635-1687           AC067817.10        85481-85533
            1688-1813           AC067817.10        90518-90643
            1814-1890           AC067817.10        92826-92902
            1891-1934           AC067817.10        94580-94623
            1935-2095           AC067817.10        96643-96803
            2096-2202           AC067817.10        97645-97751
            2203-2323           AC067817.10        101055-101175
            2324-7397           AC067817.10        102311-107384
FEATURES             Location/Qualifiers
     source          1..7397
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p11.22"
     gene            1..7397
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /note="transforming acidic coiled-coil containing protein
                     1"
                     /db_xref="GeneID:6867"
                     /db_xref="HGNC:HGNC:11522"
                     /db_xref="MIM:605301"
     exon            1..135
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..2392
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /note="isoform 9 is encoded by transcript variant 9;
                     gastric cancer antigen Ga55; taxin-1"
                     /codon_start=1
                     /product="transforming acidic coiled-coil-containing
                     protein 1 isoform 9"
                     /protein_id="NP_001339711.1"
                     /db_xref="GeneID:6867"
                     /db_xref="HGNC:HGNC:11522"
                     /db_xref="MIM:605301"
                     /translation="MGGSHSQTPRGREPAGERHPRPTETASDSEGNFETPEAETPIRS
                     PFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSH
                     SVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPP
                     DALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGE
                     FSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTND
                     SGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSA
                     GLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
                     NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLA
                     LDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFEC
                     SNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLD
                     GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM
                     IEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEE
                     ALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRK
                     EQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD"
     exon            136..251
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            252..1365
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1426
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1634
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1687
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1813
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1890
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1891..1934
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            1935..2095
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2202
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..2323
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     exon            2324..7397
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7374..7379
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /note="hexamer: AATAAA"
     polyA_site      7397
                     /gene="TACC1"
                     /gene_synonym="Ga55"
                     /note="major polyA site"
ORIGIN      
        1 gcacagccgc ccgccgccca gcacaggagg gtgcagcccc ggccccaagt tctgcgccat
       61 gggaggctcc cactctcaga ccccgagggg ccgggaaccc gccggggaga ggcacccgag
      121 acccacggag accgcctcgg attctgaagg taattttgag actcctgaag ctgaaacccc
      181 gatccgatca cctttcaagg agtcctgtga tccatcactc ggattggcag gacctggggc
      241 caaaagccaa gaatcacaag aagctgatga acagcttgta gcagaagtgg ttgaaaaatg
      301 ttcatctaag acttgttcta aaccttcaga aaatgaagtg ccacagcagg ccattgactc
      361 tcactcagtc aagaatttca gagaagaacc tgaacatgat tttagcaaaa tttccatcgt
      421 gaggccattt tcaatagaaa cgaaggattc cacggatatc tcggcagtcc tcggaacaaa
      481 agcagctcat ggctgtgtaa ctgcagtctc aggcaaggct ctgccttcca gcccgccaga
      541 cgccctccag gacgaggcga tgacagaagg cagcatgggg gtcaccctcg aggcctccgc
      601 agaagctgat ctaaaagctg gcaactcctg tccagagctt gtgcccagca gaagaagcaa
      661 gctgagaaag cccaagcctg tccccctgag gaagaaagca attggaggag agttctcaga
      721 caccaacgct gctgtggagg gcacacctct ccccaaggca tcctatcact tcagtcctga
      781 agagttggat gagaacacaa gtcctttgct aggagatgcc aggttccaga agtctccccc
      841 tgaccttaaa gaaactcccg gcactctcag tagtgacacc aacgactcag gggttgagct
      901 gggggaggag tcgaggagct cacctctcaa gcttgagttt gatttcacag aagatacagg
      961 aaacatagag gccaggaaag cccttccaag gaagcttggc aggaaactgg gtagcacact
     1021 gactcccaag atacaaaaag atggcatcag taagtcagca ggtttagaac agcctacaga
     1081 cccagtggca cgagacgggc ctctctccca aacatcttcc aagccagatc ctagtcagtg
     1141 ggaaagcccc agcttcaacc cctttgggag ccactctgtt ctgcagaact ccccacccct
     1201 ctcttctgag ggctcctacc actttgaccc agataacttt gacgaatcca tggatccctt
     1261 taaaccaact acgaccttaa caagcagtga cttttgttct cccactggta atcacgttaa
     1321 tgaaatctta gaatcaccca agaaggcaaa gtcgcgttta ataacgagtg gctgtaaggt
     1381 gaagaagcat gaaactcagt ctctcgccct ggatgcatgt tctcgggatg aaggggcagt
     1441 gatctcccag atttcagaca tttctaatag ggatggccat gctactgatg aggagaaact
     1501 ggcatccacg tcatgtggtc agaaatcagc tggtgccgag gtgaaaggtg agccagagga
     1561 agacctggag tactttgaat gttccaatgt tcctgtgtct accataaatc atgcgttttc
     1621 atcctcagaa gcaggcatag agaaggagac gtgccagaag atggaagaag acgggtccac
     1681 tgtgcttggg ctgctggagt cctctgcaga gaaggcccct gtgtcggtgt cctgtggagg
     1741 tgagagcccc ctggatggga tctgcctcag cgaatcagac aagacagccg tgctcacctt
     1801 aataagagaa gagataatta ctaaagagat tgaagcaaat gaatggaaga agaaatacga
     1861 agagacccgg caagaagttt tggagatgag gaaaattgta gctgaatatg aaaagactat
     1921 tgctcaaatg attgaagatg aacaaaggac aagtatgacc tctcagaaga gcttccagca
     1981 actgaccatg gagaaggaac aggccctggc tgaccttaac tctgtggaaa ggtccctttc
     2041 tgatctcttc aggagatatg agaacctgaa aggtgttctg gaagggttca agaagaatga
     2101 agaagccttg aagaaatgtg ctcaggatta cttagccaga gttaaacaag aggagcagcg
     2161 ataccaggcc ctgaaaatcc acgcagaaga gaaactggac aaagccaatg aagagattgc
     2221 tcaggttcga acaaaagcaa aggctgagag tgcagctctc catgctggac tccgcaaaga
     2281 gcagatgaag gtggagtccc tggaaagggc cctgcagcag aagaaccaag aaattgaaga
     2341 actgacaaaa atctgtgatg agctgattgc aaagctggga aagactgact gagacactcc
     2401 ccctgttagc tcaacagatc tgcatttggc tgcttctctt gtgaccacaa ttatcttgcc
     2461 ttatccagga ataattgccc ctttgcagag aaaaaaaaaa acttaaaaaa agcacatgcc
     2521 tactgctgcc tgtcccgctt tgctgccaat gcaacagccc tggaagaaac cctagagggt
     2581 tgcatagtct agaaaggagt gtgacctgac agtgctggag cctcctagtt tccccctatg
     2641 aaggttccct taggctgctg agtttgggtt tgtgatttat ctttagtttg ttttaaagtc
     2701 atctttactt tcccaaatgt gttaaatttg taactcctct ttggggtctt ctccaccacc
     2761 tgtctgattt ttttgtgatc tgtttaatct tttaattttt tagtatcagt ggttttattt
     2821 aaggagacag tttggcctat tgttacttcc aatttataat caagaagggg ctctggatcc
     2881 ccttttaaat tacacacact ctcacacaca tacatgtatg tttatagatg ctgctgctct
     2941 tttccctgaa gcatagtcaa gtaagaactg ctctacagaa ggacatattt ccttggatgt
     3001 gagaccctat tttgaaatag agtcctgact cagaacacca acttaagaat ttgggggatt
     3061 aaagatgtga agaccacagt cttgggtttt catatctgga gaagactatt tgccatgacg
     3121 ttttgttgcc ctggtatttg gacactcctc agctttaatg ggtgtggccc ctttagggtt
     3181 agtcctcaga ctaatgatag tgtctgcttt ctgcatgaac ggcaatatgg gactccctcc
     3241 aagctagggt ttggcaagtc tgccctagag tcatttactc tcctctgcct ccatttgtta
     3301 atacagaatc aacatttagt cttcattatc tttttttttt tttttgagac agagtttcga
     3361 tctattttaa gtatgtgaag aaaatctact tgtaaaaggc tcagatctta attaaaaggt
     3421 aattgtagca cattaccaat tataaggtga agaaatgttt ttttcccaag tgtgatgcat
     3481 tgttcttcag atgttgaaaa gaaagcaaaa aataccttct aacttaagac agaattttta
     3541 acaaaatgag cagtaaaagt cacatgaacc actccaaaaa tcagtgcatt ttgcatattt
     3601 ttaaacaaag acagcttgtt gaatactgag aagaggagtg caaggagaag gtctgtacta
     3661 acaaagccaa attcctcaag ctcttactgg actcagttca gagtggtggg ccattaaccc
     3721 caacatggaa tttttccata taaatctcaa tgaattccct ttcatttgaa taggcaaacc
     3781 caaatccatg caagtgtttt aaagcactgt cctgtcttaa tcttacatgc tgaaagtctt
     3841 catggtgata tgcactatat tcagtatacg tatgttttcc tacttctctt gtaaaactgt
     3901 tgcatgatcc aacttcagca atgaattgtg cctagtggag aacctctata gatcttaaaa
     3961 aatgaattat tctttagcag tgtattactc acatgggtgc aatctttagc cccagggagg
     4021 tcaataatgt cttttaaagc cagaagtcac attttaccaa tatgcattta tcataattgg
     4081 tgcttaggct gtatattcaa gcctgttgtc ttaacatttt gtataaaaaa gaacaacaga
     4141 aattatctgt catttgagaa gtggcttgac aatcatttga gctttgaaag cagtcactgt
     4201 ggtgtaatat gaatgctgtc ctagtggtca tagtaccaag ggcacgtgtc tccccttggt
     4261 ataactgatt tcctttttag tcctctactg ctaaataagt taattttgca ttttgcagaa
     4321 agaaacattg attgctaaat ctttttgctg ctgtgttttg gtgttttcat gtttacttgt
     4381 tttatattga tctgttttaa gtatgagagg cttatagtgc cctccattgt aaatccatag
     4441 tcatcttttt aagcttattg tgtttaagaa agtagctatg tgttaaacag aggtgatggc
     4501 agcccttccc tagcacactg gtggaagaga ccccttaaga acctgacccc agtgaatgaa
     4561 gctgatgcac agggagcacc aaaggacctt cgttaagtga taattgtcct ggcctctcag
     4621 ccatgaccgt tatgaggaaa tatcccccat tcgaacttaa cagatgcctc ctctccaaag
     4681 agaattaaaa tcgtagcttg tacagatcaa gagaatatac tgggcagaat gaagtatgtt
     4741 tgtttatttt tctttaaaaa taaaggattt tggaactctg gagagtaaga atatagtata
     4801 gagtttgcct caacacatgt gagggccaaa taacctgcta gctaggcagt aataaactct
     4861 gttacagaag agaaaaaggg ccgggcacag tggcttattc ctgtaatccc aacactgtgg
     4921 aaggccgagg caggaggatc acttgagtcc aggagtttga aacctaccta ggcaacatgg
     4981 tgaaaccttg tctctaccaa aataaaaatt agctgggcat ggtggcacgt gcctgtggtc
     5041 ccagctactt gggaggctga ggtgggagcc tgggaggtca aggctgcagt gagccatgat
     5101 catgccactg cactccatcc tgggtgacag caagatcttg tctcaaaaaa aaaaaaaaaa
     5161 aaaaaaaaac caggagtgaa aaaggaaagt agaaggcagc tgctggccta gatgttggtt
     5221 tgggaatatt aggtgatcct gttgagattc tggatccaga gcaatttctt tagcttttga
     5281 ctttgccaaa gtgtagatag cctttatcca gcagtatttt aagtggggaa tgcaacgtga
     5341 ggccaactga acaattcccc ccgtggctgc ccagatagtc acagtcaagg ttggagagtc
     5401 tccttccagc cagtgaccta cccaaacctt ttgttctgta aaactgctct ggaaataccg
     5461 ggaagcccag ttttctcacg tggtttctag cttcttcaga ctcagcccaa attaggaagt
     5521 gcagaagcac atgatggtga aaaacctagg atttggcagc cttccagaat ggtatggaat
     5581 ctgagggaag atttatgttt cgttttggag gatagctcaa gttgaatttt ctttccagcc
     5641 agttaccctt tcaacctacc catactttgt acaactctta cacaaatact tagatattta
     5701 ttagatagcc ctgaattcac tctaattata aacagggagt gtaaactgcc cccagatgtt
     5761 cctgggctgg gtaaaagcag ctggagtgaa gcactcattt tccataaagg taacaaaggg
     5821 cagctcagtg gttactcaag ctcaaaaggg tttttttaag agcaagcatt ggttaagtct
     5881 gtgtatactg agttggaagt gatttcagca cattcttttt tagtggagtg aaagttctga
     5941 agcccccttt taacttcctc ttggtttttc attataattg gtagccatct catgaactgt
     6001 ctctgactgt tgtctctttg tggtcatgtg attgtgagct tgctttctga cttgcatttc
     6061 tgactttatc ctgttgttag gaagatagaa actaggtttt gaaagattac atgattcaag
     6121 cgagggattt taaagtaaag atgtatttat tctgaagaat ctaaaagata acagattatt
     6181 tgcttatgaa agaacaatat agtctgggaa tcccagaatg tcaagccaaa ggtctaagaa
     6241 gtcatctcct tcaaatactt taataaagaa gtatttcgag gagatatctg tccaaaaagg
     6301 tttgactggc ctccagattc cagttatttt taaaaagcaa cttaccacta aatccttgag
     6361 tctccataga gtaacagtaa agaaactgat gtaacagact ctcctctcaa aggatctcct
     6421 ctggaagaga ctatcagcgg cagcattctc cagggaagac ccatccccta gtgccagagc
     6481 ttgcatcctg gagactaaag attgcacttt tttgtagttt tttgtccaaa tgcaatccca
     6541 tttctgtgcc tcttagcatg cagttagatt tggacaaaca agattcctaa ggaatgactt
     6601 tattaactat aatatggtta cagctattat ataaatatat attctggtta tagttctaat
     6661 atggagatgt tgtgtgcaat gctggcctgt ggtggtctgt gtaatgcttt aacttgtatg
     6721 gaggaggcca ggctcagagc tgagatgtgg cctgaacctt ccctgtatcg atcctttaat
     6781 ttagaactgt caagatgtca ctttctcccc ctctgccttt tagtggtatc tgacatatac
     6841 tcaaaacagt aatttcctgg tcacatcatt aactgctaat tctgtattta taaagaattt
     6901 tcagatggac atgtacaaat ttgaactcaa accatcccca gtccagatac agggcagcgt
     6961 gtaggtgacc acaccagagc ctcagcctcg gtccttctca gccgtcggga taggatccag
     7021 gcatttcttt taaatctcag aggtagcagt aaacttttca gtattgctgt tagcaagtgt
     7081 gtgtttgcca atagataccc attatactaa tgtgccaagt aaatgttcat tgcacatctg
     7141 cttccactgt gttcccacgg gtgccatgaa gtgtgtgagg agcccctcat ctggagggat
     7201 gagtgctgcg ttgactactg ctatcaggat tgtgttgtgt ggaatattca tctacataaa
     7261 ttttatatgc acagtaattt ccctttttat atgtcaagta actatttgta aaagttatac
     7321 tcacaaatta ttataatgat tactaatata ttttttccat gtttcattgc ctgaataaaa
     7381 actgtttacc actgtta
//
