LOCUS       NM_175057               1060 bp    mRNA    linear   PRI 13-DEC-2024
DEFINITION  Homo sapiens trace amine associated receptor 9 (TAAR9), mRNA.
ACCESSION   NM_175057
VERSION     NM_175057.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1060)
  AUTHORS   Muller,D.J., Chiesa,A., Mandelli,L., De Luca,V., De Ronchi,D.,
            Jain,U., Serretti,A. and Kennedy,J.L.
  TITLE     Correlation of a set of gene variants, life events and personality
            features on adult ADHD severity
  JOURNAL   J Psychiatr Res 44 (9), 598-604 (2010)
   PUBMED   20006992
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1060)
  AUTHORS   Luttrell,L.M.
  TITLE     Reviews in molecular biology and biotechnology: transmembrane
            signaling by G protein-coupled receptors
  JOURNAL   Mol Biotechnol 39 (3), 239-264 (2008)
   PUBMED   18240029
  REMARK    Review article
REFERENCE   4  (bases 1 to 1060)
  AUTHORS   Liberles,S.D. and Buck,L.B.
  TITLE     A second class of chemosensory receptors in the olfactory
            epithelium
  JOURNAL   Nature 442 (7103), 645-650 (2006)
   PUBMED   16878137
  REMARK    GeneRIF: Previous studies reported TAAR expression in brain. This
            paper found TAAR expression only in olfactory epithelial cells and
            that each TAAR detects a unique set of amine ligands. TAARs seem to
            function as a family of chemosensory receptors for amines.
REFERENCE   5  (bases 1 to 1060)
  AUTHORS   Lindemann,L., Ebeling,M., Kratochwil,N.A., Bunzow,J.R., Grandy,D.K.
            and Hoener,M.C.
  TITLE     Trace amine-associated receptors form structurally and functionally
            distinct subfamilies of novel G protein-coupled receptors
  JOURNAL   Genomics 85 (3), 372-385 (2005)
   PUBMED   15718104
REFERENCE   6  (bases 1 to 1060)
  AUTHORS   Vanti,W.B., Muglia,P., Nguyen,T., Cheng,R., Kennedy,J.L.,
            George,S.R. and O'Dowd,B.F.
  TITLE     Discovery of a null mutation in a human trace amine receptor gene
  JOURNAL   Genomics 82 (5), 531-536 (2003)
   PUBMED   14559210
REFERENCE   7  (bases 1 to 1060)
  AUTHORS   Borowsky,B., Adham,N., Jones,K.A., Raddatz,R., Artymyshyn,R.,
            Ogozalek,K.L., Durkin,M.M., Lakhlani,P.P., Bonini,J.A.,
            Pathirana,S., Boyle,N., Pu,X., Kouranova,E., Lichtblau,H.,
            Ochoa,F.Y., Branchek,T.A. and Gerald,C.
  TITLE     Trace amines: identification of a family of mammalian G
            protein-coupled receptors
  JOURNAL   Proc Natl Acad Sci U S A 98 (16), 8966-8971 (2001)
   PUBMED   11459929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513524.8 and KF459634.1.
            
            On Aug 3, 2021 this sequence version replaced NM_175057.3.
            
            Summary: TAAR9 is a member of a large family of rhodopsin G
            protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7
            transmembrane domains and transduce extracellular signals through
            heterotrimeric G proteins.[supplied by OMIM, Jul 2005].
            
            ##Evidence-Data-START##
            Transcript is intronless :: AY183469.1, BC069083.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000434551.3/ ENSP00000424607.2
            polymorphic pseudogene :: PMID: 14559210
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 AL513524.8         24443-24448
            7-383               KF459634.1         1-377               c
            384-1060            AL513524.8         24826-25502
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q23.2"
     gene            1..1060
                     /gene="TAAR9"
                     /gene_synonym="TA3; TAR3; TAR9; TRAR3"
                     /note="trace amine associated receptor 9"
                     /db_xref="GeneID:134860"
                     /db_xref="HGNC:HGNC:20977"
                     /db_xref="MIM:608282"
     exon            1..1060
                     /gene="TAAR9"
                     /gene_synonym="TA3; TAR3; TAR9; TRAR3"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1060
                     /gene="TAAR9"
                     /gene_synonym="TA3; TAR3; TAR9; TRAR3"
                     /note="trace amine receptor 3; trace amine receptor 9"
                     /codon_start=1
                     /product="trace amine-associated receptor 9"
                     /protein_id="NP_778227.3"
                     /db_xref="CCDS:CCDS75520.1"
                     /db_xref="GeneID:134860"
                     /db_xref="HGNC:HGNC:20977"
                     /db_xref="MIM:608282"
                     /translation="MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAV
                     LAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGD
                     SYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFS
                     VTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYS
                     KIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLV
                     DAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTD
                     SSTTNLFSEEVETD"
ORIGIN      
        1 aaacaagaaa gcaatggtga acaatttctc ccaagctgag gctgtggagc tgtgttacaa
       61 gaacgtgaac gaatcctgca ttaaaactcc ttactcgcca ggtcctcgat ctatcctcta
      121 cgccgtcctt ggttttgggg ctgtgctggc agcgtttgga aacttactgg tcatgattgc
      181 tatccttcac ttcaaacaac tgcacacacc tacaaacttt ctgattgcgt cgctggcctg
      241 tgctgacttc ttggtgggag tcactgtgat gcccttcagc acagtgaggt ctgtggagag
      301 ctgttggtac tttggggaca gttactgtaa attccataca tgttttgaca catccttctg
      361 ttttgcttct ttatttcatt tatgctgtat ctctgttgat agatacattg ctgttactga
      421 tcctctgacc tatccaacca agtttactgt gtcagtttca gggatatgca ttgttctttc
      481 ctggttcttt tctgtcacat acagcttttc gatcttttac acgggagcca acgaagaagg
      541 aattgaggaa ttagtagttg ctctaacctg tgtaggaggc tgccaggctc cactgaatca
      601 aaactgggtc ctactttgtt ttcttctatt ctttataccc aatgtcgcca tggtgtttat
      661 atacagtaag atatttttgg tggccaagca tcaggctagg aagatagaaa gtacagccag
      721 ccaagctcag tcctcctcag agagttacaa ggaaagagta gcaaaaagag agagaaaggc
      781 tgccaaaacc ttgggaattg ctatggcagc atttcttgtc tcttggctac catacctcgt
      841 tgatgcagtg attgatgctt atatgaattt tataactcct ccttatgttt atgagatttt
      901 agtttggtgt gtttattata attcagctat gaaccccttg atttatgctt tcttttacca
      961 atggtttggg aaggcaataa aacttattgt aagcggcaag gtcttaagga ctgattcgtc
     1021 aacaactaat ttattttctg aagaagtaga gacagattaa
//
