LOCUS       NM_001365999           14136 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens SZT2 subunit of KICSTOR complex (SZT2), transcript
            variant 1, mRNA.
ACCESSION   NM_001365999 XM_006710501
VERSION     NM_001365999.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14136)
  AUTHORS   Zhang,X., Han,Y., Yang,L., Xu,N., Zhu,L., Qiu,S., Li,Y., Xu,L. and
            Yu,X.
  TITLE     Clinical phenotype and genetic characteristics of SZT2 related
            diseases: A case report and literature review
  JOURNAL   Seizure 114, 111-120 (2024)
   PUBMED   38134649
  REMARK    GeneRIF: Clinical phenotype and genetic characteristics of SZT2
            related diseases: A case report and literature review.
            Review article
REFERENCE   2  (bases 1 to 14136)
  AUTHORS   Cattelani,C., Battistella,I., Di Leva,F., Fioravanti,G.,
            Benedicenti,F., Stanzial,F., Schwienbacher,C., Fanelli,F.,
            Pramstaller,P.P., Hicks,A.A., Conti,L. and Corti,C.
  TITLE     Induced Pluripotent Stem Cell (iPSC) Lines from a Family with
            Resistant Epileptic Encephalopathy Caused by Compound Heterozygous
            Mutations in SZT2 Gene
  JOURNAL   Int J Mol Sci 23 (21), 13095 (2022)
   PUBMED   36361881
  REMARK    GeneRIF: Induced Pluripotent Stem Cell (iPSC) Lines from a Family
            with Resistant Epileptic Encephalopathy Caused by Compound
            Heterozygous Mutations in SZT2 Gene.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 14136)
  AUTHORS   Yang,S., Yang,L.M., Liao,H.M., Fang,H.J., Ning,Z.S., Liao,C.S. and
            Wu,L.W.
  TITLE     Genetic analysis of developmental and epileptic encephalopathy
            caused by novel biallelic SZT2 gene mutations in three Chinese Han
            infants: a case series and literature review
  JOURNAL   Neurol Sci 43 (8), 5039-5048 (2022)
   PUBMED   35352205
  REMARK    GeneRIF: Genetic analysis of developmental and epileptic
            encephalopathy caused by novel biallelic SZT2 gene mutations in
            three Chinese Han infants: a case series and literature review.
            Review article
REFERENCE   4  (bases 1 to 14136)
  AUTHORS   Cattelani,C., Lesiak,D., Liebscher,G., Singer,I.I., Stasyk,T.,
            Wallnofer,M.H., Heberle,A.M., Corti,C., Hess,M.W., Pfaller,K.,
            Kwiatkowski,M., Pramstaller,P.P., Hicks,A.A., Thedieck,K.,
            Muller,T., Huber,L.A. and Eca Guimaraes de Araujo,M.
  TITLE     The SZT2 Interactome Unravels New Functions of the KICSTOR Complex
  JOURNAL   Cells 10 (10), 2711 (2021)
   PUBMED   34685691
  REMARK    GeneRIF: The SZT2 Interactome Unravels New Functions of the KICSTOR
            Complex.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 14136)
  AUTHORS   El Halabi,T., Dirani,M., Hotait,M., Nasreddine,W. and Beydoun,A.
  TITLE     A novel possible familial cause of epilepsy of infancy with
            migrating focal seizures related to SZT2 gene variant
  JOURNAL   Epilepsia Open 6 (1), 73-78 (2021)
   PUBMED   33681650
  REMARK    GeneRIF: A novel possible familial cause of epilepsy of infancy
            with migrating focal seizures related to SZT2 gene variant.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 14136)
  AUTHORS   Wolfson,R.L., Chantranupong,L., Wyant,G.A., Gu,X., Orozco,J.M.,
            Shen,K., Condon,K.J., Petri,S., Kedir,J., Scaria,S.M.,
            Abu-Remaileh,M., Frankel,W.N. and Sabatini,D.M.
  TITLE     KICSTOR recruits GATOR1 to the lysosome and is necessary for
            nutrients to regulate mTORC1
  JOURNAL   Nature 543 (7645), 438-442 (2017)
   PUBMED   28199306
  REMARK    GeneRIF: identification of a protein complex (KICSTOR) that is
            composed of four proteins, KPTN, ITFG2, C12orf66 and SZT2, and that
            is required for amino acid or glucose deprivation to inhibit mTORC1
            in cultured human cells
REFERENCE   7  (bases 1 to 14136)
  AUTHORS   Falcone,M., Yariz,K.O., Ross,D.B., Foster,J. 2nd, Menendez,I. and
            Tekin,M.
  TITLE     An amino acid deletion inSZT2 in a family with non-syndromic
            intellectual disability
  JOURNAL   PLoS One 8 (12), e82810 (2013)
   PUBMED   24324832
  REMARK    GeneRIF: We conclude that the disruption of SZT2 with some residual
            function might lead to mild or moderate intellectual disability
            without seizures.
            Publication Status: Online-Only
REFERENCE   8  (bases 1 to 14136)
  AUTHORS   Basel-Vanagaite,L., Hershkovitz,T., Heyman,E., Raspall-Chaure,M.,
            Kakar,N., Smirin-Yosef,P., Vila-Pueyo,M., Kornreich,L., Thiele,H.,
            Bode,H., Lagovsky,I., Dahary,D., Haviv,A., Hubshman,M.W.,
            Pasmanik-Chor,M., Nurnberg,P., Gothelf,D., Kubisch,C., Shohat,M.,
            Macaya,A. and Borck,G.
  TITLE     Biallelic SZT2 mutations cause infantile encephalopathy with
            epilepsy and dysmorphic corpus callosum
  JOURNAL   Am J Hum Genet 93 (3), 524-529 (2013)
   PUBMED   23932106
  REMARK    GeneRIF: mutations in SZT2 cause a severe type of
            autosomal-recessive infantile encephalopathy.
REFERENCE   9  (bases 1 to 14136)
  AUTHORS   Toutzaris,D., Lewerenz,J., Albrecht,P., Jensen,L.T., Letz,J.,
            Geerts,A., Golz,S. and Methner,A.
  TITLE     A novel giant peroxisomal superoxide dismutase motif-containing
            protein
  JOURNAL   Free Radic Biol Med 48 (6), 811-820 (2010)
   PUBMED   20045724
REFERENCE   10 (bases 1 to 14136)
  AUTHORS   Xie,H., Diber,A., Pollock,S., Nemzer,S., Safer,H., Meloon,B.,
            Olson,A., Hwang,J.J., Endress,G.A., Savitsky,K. and Gill-More,R.
  TITLE     Bridging expressed sequence alignments through targeted cDNA
            sequencing
  JOURNAL   Genomics 83 (4), 572-576 (2004)
   PUBMED   15028280
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL139289.6 and AL583862.35.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Sep 20, 2018 this sequence version replaced XM_006710501.3.
            
            Summary: The protein encoded by this gene is expressed in the
            brain, predominantly in the parietal and frontal cortex as well as
            in dorsal root ganglia. It is localized to the peroxisome, and is
            implicated in resistance to oxidative stress. It likely functions
            by increasing superoxide dismutase (SOD) activity, but itself has
            no direct SOD activity. Studies in mice show that this gene confers
            low seizure threshold, and may also enhance epileptogenesis.
            [provided by RefSeq, Jun 2011].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1965299,
                              SAMEA1966682 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000634258.3/ ENSP00000489255.1
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                AL139289.6         70829-70925
            98-223              AL139289.6         84107-84232
            224-397             AL139289.6         84531-84704
            398-568             AL139289.6         85310-85480
            569-700             AL583862.35        7579-7710
            701-842             AL583862.35        8457-8598
            843-949             AL583862.35        9032-9138
            950-1160            AL583862.35        12231-12441
            1161-1331           AL583862.35        12650-12820
            1332-1566           AL583862.35        13246-13480
            1567-1696           AL583862.35        13671-13800
            1697-1839           AL583862.35        14580-14722
            1840-1992           AL583862.35        14977-15129
            1993-2107           AL583862.35        15266-15380
            2108-2325           AL583862.35        15596-15813
            2326-2541           AL583862.35        16714-16929
            2542-2620           AL583862.35        17281-17359
            2621-2715           AL583862.35        17610-17704
            2716-2884           AL583862.35        17971-18139
            2885-2999           AL583862.35        18332-18446
            3000-3113           AL583862.35        18535-18648
            3114-3284           AL583862.35        18865-19035
            3285-3379           AL583862.35        19212-19306
            3380-3503           AL583862.35        19553-19676
            3504-3668           AL583862.35        19778-19942
            3669-3873           AL583862.35        20027-20231
            3874-3989           AL583862.35        20500-20615
            3990-4236           AL583862.35        20737-20983
            4237-4378           AL583862.35        22200-22341
            4379-4471           AL583862.35        22508-22600
            4472-4550           AL583862.35        22808-22886
            4551-4844           AL583862.35        22993-23286
            4845-4986           AL583862.35        23446-23587
            4987-5094           AL583862.35        23762-23869
            5095-5158           AL583862.35        23957-24020
            5159-5344           AL583862.35        24213-24398
            5345-5512           AL583862.35        24769-24936
            5513-5600           AL583862.35        25014-25101
            5601-5672           AL583862.35        25225-25296
            5673-5874           AL583862.35        25486-25687
            5875-5974           AL583862.35        26883-26982
            5975-6104           AL583862.35        27697-27826
            6105-6257           AL583862.35        29668-29820
            6258-6360           AL583862.35        29903-30005
            6361-6466           AL583862.35        30092-30197
            6467-6578           AL583862.35        30288-30399
            6579-6697           AL583862.35        31196-31314
            6698-6862           AL583862.35        31426-31590
            6863-6947           AL583862.35        31855-31939
            6948-7112           AL583862.35        32102-32266
            7113-7280           AL583862.35        32378-32545
            7281-7414           AL583862.35        32950-33083
            7415-7581           AL583862.35        33711-33877
            7582-7679           AL583862.35        34001-34098
            7680-7812           AL583862.35        34183-34315
            7813-7943           AL583862.35        34497-34627
            7944-8044           AL583862.35        34765-34865
            8045-8221           AL583862.35        34939-35115
            8222-8489           AL583862.35        35316-35583
            8490-8569           AL583862.35        35685-35764
            8570-8695           AL583862.35        35849-35974
            8696-8895           AL583862.35        36094-36293
            8896-8986           AL583862.35        38391-38481
            8987-9067           AL583862.35        38676-38756
            9068-9142           AL583862.35        38839-38913
            9143-9356           AL583862.35        39452-39665
            9357-9510           AL583862.35        40042-40195
            9511-9633           AL583862.35        40346-40468
            9634-10039          AL583862.35        40576-40981
            10040-10156         AL583862.35        41109-41225
            10157-10225         AL583862.35        42600-42668
            10226-14136         AL583862.35        42834-46744
FEATURES             Location/Qualifiers
     source          1..14136
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.2"
     gene            1..14136
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /note="SZT2 subunit of KICSTOR complex"
                     /db_xref="GeneID:23334"
                     /db_xref="HGNC:HGNC:29040"
                     /db_xref="MIM:615463"
     exon            1..97
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..10369
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /note="isoform 1 is encoded by transcript variant 1;
                     seizure threshold 2 protein homolog; KICSTOR complex
                     protein SZT2; SZT2, KICSTOR complex subunit; SZT2 subunit
                     KICSTOR complex"
                     /codon_start=1
                     /product="KICSTOR complex protein SZT2 isoform 1"
                     /protein_id="NP_001352928.1"
                     /db_xref="CCDS:CCDS90935.1"
                     /db_xref="GeneID:23334"
                     /db_xref="HGNC:HGNC:29040"
                     /db_xref="MIM:615463"
                     /translation="MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQ
                     ATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDL
                     SPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSII
                     GLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDS
                     GDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCE
                     TLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPG
                     NLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTE
                     KEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLE
                     PEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLA
                     HLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVL
                     SMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDW
                     SSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVS
                     GLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLV
                     VLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRW
                     LWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQ
                     AAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQY
                     GRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEP
                     RVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVPFAEGSCPAND
                     MVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGVHGIPKEQA
                     VGSTQATGDSAFTSLSVGLPETLKPLISAQPPQWRCYARLVNPQHVFLTFLPATFSDV
                     QRLAACGLEGPPQEETKPKFGDWSGAPSLKDLGGTGIKATKSHVPVLSVTLASDNAQN
                     QGELSPPFRRDLQAYAGRQASQTESADGPRTRCPVYIYSCSLEALREQMVGMQPPQAP
                     RDLIFRTQFLDHPSPSSAWMEPRYKEAANHCALLQEHAQRCYVRGLFRSLQQAQSVTS
                     QDLLTAVDACEELLQEIDITPFLLALCGHTWGLPHAPPSPGPLSPGPFSSSMEEGAEP
                     RERAILASESSIETEDLSEPEFQSTRVPGIPDPGPEISLTDVCQLRGEAHGALHSVIQ
                     EKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELMGEEG
                     DTSACCVVTESDPELEVEYRESRESDLGPAGLDSASLSDVDTVNPDEDSFSILGGDSP
                     TGPESFLHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLR
                     DLSVTLDVFMLTLPLEVELPTASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPL
                     PPPEEERHPGLSNLATPHRLAIETTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAH
                     IHSSPGRSTCLRQTLPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAG
                     QQPGGSHGEPSSAAWAWHSHEDRAEGIEGETLTASPQAPGSPEDSEGVPLISLPRVPQ
                     GGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPNDTLGEKAPFTLRTPPGPA
                     PPQPSLSGLPGPCLPDFWLIVRVLQDRVEVYAHARSLIREDGGPGTECRHLQQLLVRR
                     VGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAPLPSDDYAAD
                     ESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAF
                     SVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWKGDALPPSLALSRSQEPIYSEEAS
                     GPRSPLDMVSSRSSDAARPVGQVDRHIQLLVHGVGQAGPEITDELVRVLCRRLDEATL
                     DVITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLALPTSCRPWLPALAWYLRQNLLIF
                     LHSPKYTDSNSRNHFQHPLPPQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVDEGG
                     APLSLALWPPSSPGPPDPLREEEFEQLTQVIRCPVVVDSSSAQNGAPRLRLDVWEKGN
                     ISIVQLEEKLRGAARQALADAIIELQLLPASLCTEDTPTGSLRNGSLETKSSAGRAST
                     FPPAPVPGEPVTPPSKAGRRSFWDMLSKTECGDLGSPKTTDDIVLDRPEDTRGRRRHK
                     TESVRTPGGAERAPGSDSGAQRQKRRTTQLEEGEVGTLHPVFARVAQRWMEFMVQIGC
                     ASVSRSSAHMVSRFLLPSILSEFTALVTSMAGDTSVRIFEQHLGSEPEIFGPCSPGQL
                     GPSPRPAAERHLLLLGRNFLQWRRPTQQAAKAMQRFEPGGDGSSGRNAPRQRLLLLEV
                     VDKKLQLLTYNWAPDLGAALGRALVRLVQWQNARAHLIFCLLSQKLGLFHHYGQLDFP
                     VRDEKEPNPFLLPTMEVETLIRSASPPLSREQGRLSGSSRGGGPLPLDTFPFDEALRD
                     ITAARPSSVLGPVPRPPDPVTYHGQQFLEIKMAERRELERQMKMENLFVTWQQRSTPA
                     TMPISAGELETLKQSSRLVHYCATAMLFDPAAWLHGPPETSGPPDGQRRHRPESGSGS
                     REAPTSCESLDVSPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTS
                     RPRAMAILGTEGRGSFSCPKTKTDGSPKSTSSPVTTYHLQRALPGGIILMELAFQGCY
                     FCVKQFALECSRIPMGQAVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLG
                     AHLVLRHGYHLTTFLRHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHA
                     SSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHCAAPF
                     EEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPPRLPPEPEAPGSSAGSPGE
                     ASGLILAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDR
                     LRLGGRLALAELEELLEAVHAKSIGDIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCR
                     HFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQ
                     LVSTYHHLESVINTACFTLWTRLL"
     exon            98..223
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            224..397
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            398..568
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            569..700
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            701..842
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            843..949
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1160
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1331
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1566
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1696
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1839
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..1992
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..2107
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2325
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2541
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2620
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2715
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2884
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            2885..2999
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3000..3113
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3114..3284
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3285..3379
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3380..3503
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3504..3668
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3669..3873
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3874..3989
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            3990..4236
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4237..4378
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4379..4471
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4472..4550
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4551..4844
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4845..4986
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            4987..5094
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5095..5158
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5159..5344
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5345..5512
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5513..5600
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5601..5672
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5673..5874
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5875..5974
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            5975..6104
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6105..6257
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6258..6360
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6361..6466
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6467..6578
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6579..6697
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6698..6862
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6863..6947
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            6948..7112
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7113..7280
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7281..7414
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7415..7581
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7582..7679
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7680..7812
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7813..7943
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            7944..8044
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8045..8221
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8222..8489
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8490..8569
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8570..8695
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8696..8895
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8896..8986
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            8987..9067
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            9068..9142
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            9143..9356
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            9357..9510
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            9511..9633
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            9634..10039
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            10040..10156
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            10157..10225
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     exon            10226..14136
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      14111..14116
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /note="hexamer: AATAAA"
     polyA_site      14136
                     /gene="SZT2"
                     /gene_synonym="C1orf84; DEE18; EIEE18; KIAA0467; KICS1;
                     SZT2A; SZT2B"
                     /note="major polyA site"
ORIGIN      
        1 gaggtagcga ggtcaggggt caagagtgga acaccctcac tggcccgggc cggcgcggga
       61 gggctgtgtg atggcctcgg agcgcccgga gccggaggtg gaagaagctg ggcaggtgtt
      121 cctgttaatg aaaaaggatt atcgaatctc ccgaaatgtt cgcctggctt ggttcctcag
      181 tcatctgcac caaactgtgc aggccacacc ccaggagatg ctgcttcagt ctgaacagga
      241 attggaagtc ctcagtgtcc tgccccctgg gtggcagcca gatgaaccag tggtcccaag
      301 gccattcctc ctggtacctt ccacccgggt caccttcctg gcttggcagt atcggtttgt
      361 cattgagttg gaccttagcc catctactgg cattgtggat gattccacag gggagatctt
      421 gtttgatgaa gttttccatg ccctgtcccg ctgcttaggc gggctgcttc ggcccttccg
      481 agtgcctgga tcttgcatcg acttccagcc tgagatctat gtaactatcc aggcctactc
      541 ctccatcatt ggactgcagt cccaccaggt gctggtacag ggctgcctct tggacccttc
      601 ccagcgggag gtgttcctgc agcagatata tgagcagctc tgcctctttg aggataaggt
      661 ggccaccatg ctgcagcagc agtacgatcc ccagagccag gcagaagacc agtccccaga
      721 ctcaggggac ctactgggcc ggaaggtagg cgtctccatg gtgacagctg atcttgggct
      781 ggtcagtatg attcgtcagg gcatcttggc actgcagtta ctaccctcga actctagtgc
      841 agggattatc gtgatcacgg atggggtgac cagtgtacct gatgttgctg tctgtgagac
      901 actgctgaac cagcttcgca gtggcactgt ggcttgttcc tttgtccagg tgggaggagt
      961 ttactcttat gactgcagtt ttggccatgt gcccaatgtg gaattaatga agttcatcgc
     1021 aatggcaaca tttgggtcct acctgtccac ttgtcctgag ccggagccag gcaacctggg
     1081 tctgactgtc taccaccggg catttctcct ctattccttc ctgcgcagtg gggaagcact
     1141 gaaccctgaa tattactgcg gctctcagca ccgcctattt aatgagcacc tggtctctgc
     1201 aagcagcaac cctgccctgg ccttgcgccg gaagaagcac actgagaagg aggtgccagc
     1261 cgacttggtc agcactgtgt ccgtacggct tcgagagggc tacagtgtcc gagaggtcac
     1321 actggccaaa ggagggtccc aattggaggt aaagctggtg ctgctgtgga aacacaacat
     1381 gcgcattgag tatgtggcta tggcaccctg gcccctggag cctgagggcc ctcgagtaac
     1441 acgggtggaa gtgacgatgg aaggcggcta cgacattttg catgatgtgt cctgtgcact
     1501 aaggcagccc attcgttcat tgtatcgtac ccatgttatc cggcgtttct ggaacacgct
     1561 gcagagcatc aaccagacag accagatgct tgcccacctt cagtccttct cctcagtgcc
     1621 tgagcatttc acgcttcctg acagcaccaa gagcggagtg ccactcttct acatccctcc
     1681 aggctccacc accccggtgc tctccctcca gcccagtggt tctgactcat cccatgccca
     1741 gtttgctgcc tactggaagc cagtgctgtc catggatgca aattcctggc agcgatggct
     1801 gcacatgcat cgcctggtgc taatcctgga gcatgacaca ccaatcccca agcacttgca
     1861 caccccgggc agcaatgggc gctacagcac tatccagtgc aggatctccc actcctccct
     1921 gacctctctg ctgcgggact ggagcagctt cgtactagtc gagggctatt cttatgttaa
     1981 gctgctctcc agtgccccag accagccccc caattccttc tacatggtcc gtatcatttc
     2041 caaggcccca tgcatggttc ttcgcctggg ttttcccatt ggcacaccag caccggcccg
     2101 gcacaagatt gtgtcaggct tgagggaaga gatcctgcgg ctgcgtttcc cccaccgggt
     2161 acaaagcaag gagccaacgc ccaaggtgaa acgaaaaggg ctagggggtg ctggtggggg
     2221 cagctctccc tccaagtcac cccccgtgct ggggccacag caggccctgt ctgaccggcc
     2281 ctgccttgtg gtcctgcata agccactgga caaactgctc atcaggtatg agaagctgcc
     2341 cttggactac cgggcaccct tcttgctgac attggagcca ccaggtccac tgcccttggt
     2401 gtcaggccgc tcagcctctt ctagcctggc gtcactgtcc cgctacctct accatcagcg
     2461 ctggctttgg agtgtcccgt caggactggc ccctgcgctg cctctcagtg ccattgccca
     2521 gctcctctcc atcctcactg aagtccgact ttctgaagga ttccacttcg cctgcagtgg
     2581 ggaaggaatc atcaacatgg ttctggagct tccaattcag aatgaaccac cagggcaggc
     2641 tgcagctgaa gagaagcaca cctgtgttgt ccagtacatc ctcttccccc cacactctac
     2701 ctccaccaaa gacagcttct cgacagatga tgacaatgat gtggaagtgg aggccctgga
     2761 gggagactca gagctcaatc tggtcactga ggtgtgggtg gagccacagt atgggcgagt
     2821 gggacctggc cctggaatct ggaagcacct ccaggacctg acgtattctg agatcccgca
     2881 agctctccac ccacgggatg ctgcctgcat aggctccatg ctgagctttg aatacctgat
     2941 acagctgtgt cagagcaagg aatggggtcc tctgccccca gagccgaggg tctctgatgg
     3001 attggatcag ggaggagaca cctgcgtcca tgagatccct ttccattttg acctaatggg
     3061 attgctgcca cagtgccagc agctccagat gttcttcctc ttgcttgcca gagagccaga
     3121 gggtgtccct ttcgccgagg ggtcctgtcc tgccaacgac atggtgctgt gcctgctgca
     3181 cagctgcctg gggcaggagc tgagtgaccg ggagatccca ctgacccccg ttgaccaggc
     3241 tgccttcttg agtgaggtgc tgcggcggac ctgccacgtt ccaggtgccg aggggccact
     3301 gctgggggtt catgggatcc cgaaggagca agcagtcggc agcacccagg ccacaggaga
     3361 ctccgctttt acttccctga gtgtaggtct tcctgaaact ctcaagcctc tcatctctgc
     3421 ccagccccct cagtggcgct gctatgcaag gcttgtgaac ccccagcatg tgtttctgac
     3481 ttttctccca gctaccttct cagatgtcca gcgtctggct gcctgtggcc tggagggacc
     3541 ccctcaagag gagacaaagc ctaagtttgg ggattggagt ggggctccca gtctgaaaga
     3601 tctaggagga actgggatca aagctacaaa gtcccacgtc cctgtcctca gtgtgaccct
     3661 ggctagtgac aatgcccaga atcaaggaga gctaagtcca ccattccgtc gagacttaca
     3721 ggcttacgct gggcgtcagg cttcccagac agagagtgcg gatgggcccc ggacccggtg
     3781 tcctgtctac atctacagct gttcactgga agcgctgagg gaacaaatgg ttggcatgca
     3841 gccccctcag gcgccccgag acctcatctt ccggactcag ttcctcgacc acccctcccc
     3901 atcctcagcc tggatggaac cccggtacaa ggaggcagct aaccactgtg ccctgctgca
     3961 ggagcatgca cagcggtgct atgtccgtgg gctattccgc agcttgcagc aagcacagag
     4021 tgtgacctcc caggatttgc tgacagcggt agatgcctgt gaggagctac tacaagaaat
     4081 agacatcacc ccatttctcc ttgcattgtg tggccacact tggggtttgc ctcatgcacc
     4141 cccaagtcct ggtcctctca gccctgggcc cttcagcagc agcatggagg agggtgctga
     4201 acctcgggaa cgagctatcc tagcttctga atccagcata gagaccgagg acctaagcga
     4261 gcctgagttt cagagcaccc gtgtccctgg cattccagac cctgggccag agatctctct
     4321 gacagatgtc tgccagctca gaggagaggc ccatggtgcc cttcatagcg tcatccagga
     4381 gaagttccta gagatcagtc gtctccactt ccgcacagtg ccttccaatc cccactactt
     4441 cttctattgc cctccatcca gcaggcgaga agatgagggg cctcgggaca cagtagacag
     4501 aaaaatcagt gacctggagt tttcagaggc tgagcttatg ggagaagaag gagacacatc
     4561 tgcctgctgt gtggtcactg agagtgaccc agagctagag gtagaatacc gggagagccg
     4621 tgaatcagac ctggggcctg ctgggctaga ctctgcctcg ctgtcagacg tagacactgt
     4681 gaatcctgat gaagactcct tcagtatctt ggggggcgac tcacccactg ggcctgagag
     4741 cttccttcat gacctgccac cgctcttcct gcacctcacg tgctccgtgc ggctacgtgg
     4801 gcagcacagc tcagtacctg tgtgcagcct gcctacctgc ctgggccagg tgctttccag
     4861 tctggagggc cccccagttg gaggccgagt tcccttgagg gacctcagtg tgactctgga
     4921 tgtcttcatg ctgactttgc ccctggaagt ggagctcccc acggcctcgg accctcagca
     4981 ccaccggtca acatctgaaa gcagtgcttc atttccacga tccccagggc agccatcatc
     5041 tttaaggtca gatgatggcc tcgggccccc actgccaccc ccagaagagg agaggcaccc
     5101 aggactatcc aatttggcca cgccccacag actggctatt gagaccacca tgaatgagat
     5161 ccgctggttg ttggaagatg agatggtggg ggcactccga agagggggca tcccacagag
     5221 tcctgccctg caccgcgcag ctgcccatat ccatagttct cctggacgct ccacctgcct
     5281 tcgccaaact ctgccactga gttttgtatt tgggccagag cgttccctca cacaattcaa
     5341 ggaggagttc cgccgcctcc atctccctgg ccatgttctt cttgaagacc ctgacagtgg
     5401 cttcttcttt gtggcagctg gccaacagcc aggtgggtcc catggggagc cttcttcagc
     5461 ggcctgggct tggcacagtc atgaggacag ggctgaaggc atcgaagggg agaccctgac
     5521 agccagcccc caagcacctg ggtccccaga ggattctgag ggtgtccccc tcatcagcct
     5581 gccccgcgtg ccacagggag ggagtcagcc tgggcccagc cggggattaa gtctcatgtc
     5641 cagtcagggc agtgtggact cagaccacct aggttatgat ggtggcagca gtggctcaga
     5701 cagtgagggt cccaatgaca cccttggtga gaaggccccc ttcacattgc ggactccacc
     5761 tgggccagca cctccacagc cttcactctc aggcctccct gggccctgcc tgcctgactt
     5821 ctggctcatt gtccgggtcc tgcaggaccg tgtggaagtg tatgcacatg cacggagcct
     5881 gattcgggag gatggggggc cgggcactga gtgtcgccac ctgcagcagc tcctggtgag
     5941 gcgagttggg gagatctgca gggaggtcaa ccagcgactg cttcttcaag accttcatga
     6001 cagccacgtg tgtaactctc ttctggtggc cgagagtgaa gaagatctgt ggcgcagtga
     6061 gactcccttc cactcccgtc agcgggcacc actgcccagt gatgattatg ctgctgatga
     6121 gagctgtgcg ccccgtgggt acctggcagc cacaatgcag tttgtccctg gccatttctc
     6181 ctgtgacgtt gtgtggggaa ctgtgatccg agtccattca cgcctcaaaa tggggcccag
     6241 catgggggtc tctcgggcca tccaggccct gcgctctgtg ctcaatgcct tctctgtggt
     6301 gaaccggaaa aacatgtttg tttaccagga gcgagcaaca aaggctgtgt actatcttcg
     6361 gctcctagag acatcctgca gtgaccggcc atggaaaggg gatgcgctgc ccccttccct
     6421 cgctctgtcc cgaagccaag agcccatcta ctctgaggaa gcctcgggtc ctcgttctcc
     6481 cttagacatg gtctctagcc gcagttcaga tgctgctcgt cctgtgggcc aagtggacag
     6541 acatatccag ctgctggtcc atggtgttgg gcaggcaggt cctgagatca cggatgagct
     6601 cgtgcgagtt ctatgtcggc gcctggatga ggccacgctg gacgtcatca cagttatgct
     6661 tgttcggaac tgcaagctga caccagctga tgtggagttc atccagcccc ctggaagtct
     6721 cccctcagag gtgctgcatc tggccctacc cacctcctgc aggccctggc ttccagccct
     6781 ggcatggtac ctacggcaga acttgctcat cttcctgcac tctcccaagt acacagatag
     6841 caacagccgg aaccacttcc aacatccact cccaccacag ggtggcctcc ctgacttgga
     6901 catctacttg tataacaagc ctggtggaca gggcactggg ggcaaagggg ttgcctgcat
     6961 cactctagcc tttgtggatg aaggaggggc ccccttgtca ctggcgttgt ggcccccctc
     7021 ctctccgggg cccccagacc cactgcgaga ggaggaattt gagcaactga cccaggtcat
     7081 ccgctgcccg gttgttgtgg acagttcttc agctcagaat ggggccccac ggcttcgatt
     7141 ggatgtgtgg gaaaagggga acattagtat tgtgcagctg gaggagaaac tccgaggagc
     7201 agctcgccag gccctggccg atgccatcat cgagcttcag ctgctgccag cttcactatg
     7261 tacagaggac acacccacag gaagtctcag gaacggatcg ttggaaacta agagctctgc
     7321 aggccgagct agcacctttc cccctgcccc tgtccctggg gagcctgtga ctccacccag
     7381 caaagcgggc cggcgtagct tctgggatat gctgagtaaa acagaatgtg gggatttggg
     7441 ttcccccaaa acaactgatg acattgtcct ggatcggcca gaagacactc ggggccggag
     7501 gcgtcacaaa accgagagtg ttcggactcc tggtggagct gagcgggcgc caggctcaga
     7561 ttctggagcc cagagacaaa agcgccggac aacacagcta gaagagggtg aggtggggac
     7621 ccttcatcct gtgtttgccc gtgttgctca gcgctggatg gagtttatgg ttcagattgg
     7681 ttgtgcctca gtgtccagaa gctctgccca catggtgtcc cggttcctcc ttccatccat
     7741 cctgtctgag ttcaccgcac tggtcacctc aatggctgga gacaccagtg tccgcatctt
     7801 tgagcagcat ttgggttcag agccagagat cttcggccct tgttcccctg ggcaactggg
     7861 cccctctccc cgccctgcag ctgagcggca tctgctgctt ctgggaagga acttcttgca
     7921 gtggaggaga ccaacacagc aggctgccaa agccatgcag cgcttcgagc caggaggtga
     7981 tgggagctca gggcgaaatg ctccccggca gaggctcttg ctactagagg ttgtggacaa
     8041 gaagctacag ctgctgacct acaactgggc tccagacctg ggggcagcat tgggccgagc
     8101 gctggttcgc ctggtgcagt ggcagaatgc acgagcccat ctcatcttct gcctactcag
     8161 ccagaagctt ggcctcttcc atcattatgg ccagttggac ttccccgtgc gagatgaaaa
     8221 ggagccaaac ccattcctgc tgccgaccat ggaagtggag accctcatcc ggagtgcaag
     8281 tcccccgctg agccgtgagc agggccgact gagtgggtcc tctcgtggtg ggggtcctct
     8341 tcccctggac acattcccct ttgacgaggc cctaagggat atcacggctg cccgccccag
     8401 ctccgtactt ggtcctgtgc ccagacctcc tgatcctgtc acctaccatg gacaacagtt
     8461 cctagagatc aagatggcag agcgcagaga gctggagcgc cagatgaaga tggaaaacct
     8521 gtttgtaacc tggcagcagc gttctacccc agccaccatg cccatcagtg ctggagagct
     8581 ggagaccctg aagcagtcat cccgcctggt gcattactgt gcaacagcca tgctcttcga
     8641 cccagctgcc tggctgcatg ggcccccaga gacctctgga ccccctgacg ggcagcggcg
     8701 ccatcgccct gagtcagggt ctgggagccg agaggccccc acaagctgtg aatccttgga
     8761 tgtgtcgccc ccgggagccc gtgaggagcc ttggctgaag gagctgagct tggctttcct
     8821 gcagcaatat gtgcagtatc tgcagagcat aggttttgtg ctggtaccac tgcggccccc
     8881 ctcacccgcc cgcagcacca gccggccacg ggccatggct atccttggaa cagagggtcg
     8941 aggctccttc tcctgcccta aaaccaagac tgatgggagc cccaagagca ctagctctcc
     9001 ggtaaccacc taccacctgc agcgggcact gcctgggggc atcatcctca tggaactggc
     9061 attccagggc tgttacttct gtgtcaaaca gtttgccctg gaatgttccc gaatcccaat
     9121 ggggcaggct gtcaactcac agctgtccat gctgttcaca gaggagtgtg acaaggtgcg
     9181 ggacctgatg cacgtgcact cgttcagcta tgacttccat ctgcgcctcg tgcatcagca
     9241 cgtgctaggt gcccatctgg tgctgcggca cggctaccac ctcaccacct ttctgcgaca
     9301 cttcctggcc caccaccctg acggacccca ctttggccgc aatcacattt accaagggac
     9361 attggagctc cccacaccac tcattgctgc ccaccagcta tacaactacg tggctgatca
     9421 cgccagctct taccacatga agccattgcg aatggcccgg ccagggggcc cagaacacaa
     9481 cgagtatgcc ctggtgtcgg catggcacag ttctggctcc tacctggact ctgagggact
     9541 tcgacaccag gatgactttg atgtgtctct gcttgtctgt cactgtgctg caccctttga
     9601 ggagcaagga gaggctgagc ggcacgttct gcggctacag ttcttcgtgg tgctcaccag
     9661 ccagcgagag ctcttcccca ggctcactgc tgacatgcgc cgcttccgga agccacccag
     9721 actgccccct gagccagagg ctcctgggag ttcagctggc agccctgggg aggcctcagg
     9781 gcttattcta gcgcctggac cggctcctct gttcccacca ctggctgcag aggtgggcat
     9841 ggcacgagca cggctggctc agctggtgcg gctggctgga gggcactgcc gtcgggacac
     9901 cctttggaag cgcctcttct tgctggagcc accggggcct gatcgactgc ggctaggggg
     9961 gcgcctggcc ctggcagagc tggaggaact cctagaagca gtccatgcca aatccattgg
    10021 ggacatcgac ccccagctgg actgcttcct atccatgacg gtctcctggt accagagcct
    10081 gatcaaagtt ctcctaagcc gcttccccca gagctgtcgc catttccaaa gcccagactt
    10141 gggaactcag tacctggttg tgctgaatca gaagttcact gactgctttg tgctagtgtt
    10201 tctggactcc cacttaggaa agacgtctct gacagtggtt ttccgagagc ccttcccagt
    10261 acagccccag gacagcgaga gcccccctgc ccaactggtc tccacctacc accacctgga
    10321 gtctgtcatc aacacagcct gtttcaccct ctggacccgc ctcctctgag ggagtggact
    10381 ggaccactga atgtcactgt tccttgaatc atgggcctac cagattgcct gccagaggca
    10441 ggactgacca gcccttctgg gccccagggc aagccagaca ctgagtgaca ccaaaggctt
    10501 tgtaactatg tcttgagggt ctgctgcccc agcctggcag caggaaccgc cctccccaaa
    10561 cacccacagc cactgaccca tccaggactc cagagagtca ggtcaacccc gaggacccct
    10621 tgggcccttc tggggtactc ctttcggccc ccctggtaga gtctcgggag ttcacacagg
    10681 gtggcaaaca ccccctagag ctcctctgcc tgaatcctgc cccctagcct ttgaccactg
    10741 tcagccacct gtgtcccttg agccttcggg tcttcacttc ccacttggac atcactgctg
    10801 gacattccca tcgagatgac acctgggttc caatcccagc tctgcctttg aagcacttgt
    10861 ggccaccgtc aagtcccttt gctctcggac cctgggtttc tcatccttta atgaggtggg
    10921 ttcagaagct ctcccatctt cacagcaacc ctggcactgg cttctcaatg ggagggaagc
    10981 agcagagaaa ctgaagtgtt agacactatg tgtcccacca ccccattaca gagacatatg
    11041 acaatgttca gcaggtcatc tttaatgcag aggaggagat gggatgtcac tcgctgtctg
    11101 gaggcacgtg ggtggtgtgc gggccctcac tggccagcct ctgggtggcc ccgcctatcc
    11161 cagtatgaac gtagccaact caagccctct actgtgtctc ctgcagggag agggaggcct
    11221 cggcacctca gcccacaagg agaaaacagc ccctgtccgg gtccctccag agctcccttc
    11281 cccagggcca cgcctcacct cgaggctgat actcacagcc cacgaagcct ttgtagcctt
    11341 catcttccag cagttgaaac agatagggga aattcagctc tccggggctg ctgggctccc
    11401 ctcggcctgg gacctgtgcc acctgcacat gccctgggga cagatgtgga caaatgtggg
    11461 gtccaggctc ctgccagggc ctgaaggaca gatgtgggga ttgaaagggt gggagggcaa
    11521 aggaaggtcc tctcaccaac aatgggcagg aactcccgga tgtttcctgt caggttccca
    11581 tccatgatct gccagtggaa tatgtcctag ggaagaggat actacattcc gagaccccgc
    11641 aggccccgcc ctccttccga tctgcgaagt acccccttcc acttaccatt tgtaattgga
    11701 ggttgggtct tcctaccttc tgtaagatgg ctgccgctgt aagagaagcc agggagggga
    11761 ccgtgagcct caagagcaca ggaatcaaaa gggacagaag gagagacagg gctggggtcg
    11821 taccctgctg gggcgtgtcc aggaagtact gggggtcagt gatgcgggtg ttgatgggct
    11881 ccagcagtcc cacgaggtcc tcctagcagc atgtcgggtg ctgtgaatag agctccttcc
    11941 caagtttgtc ccccatcagt cagtcactgg tcaaggccct cacctgttcc tctgacctag
    12001 gctggcagcc tcacgtgctg tccccactgt gcaccccctt ctccgcacac ccacagagac
    12061 atgtaagtac gtgtgtgttt ccacctttct cacctgagcc aaaaccccag ctgcatgcct
    12121 caggttctcc agaaaaacgg cctccatctc agccttgact gctattcgat cagctccctg
    12181 gggtactcgg ccagccatca ggtggatcct gtggggaaga tggactggag gccttgcctc
    12241 ccttggctct ctctgcacct cttccaggat tccctgactg tgccagccct cgtccgtctc
    12301 cccaggtctc cagtccatgg cacctgggtc acgatgccca ggtatcccag cactttcaga
    12361 gacacttcag tgatggctga ggggcaagcc ctttcccaga catctcagtg tccacccacc
    12421 gcctcctgcc tccagtactt tccaaaacct ttccttccct cggtccttct ccgcaacctg
    12481 taacctgcta aattctcacc tttaaaaatt gtcctgacct ttgcttgccc ttctcaggta
    12541 ttccatgctg ctgtctctac ttcctctcct cgcatctact tagccttttc ccatctgttt
    12601 tctgccccca ccattgacca gtagtgatcc cctcttgcca gttccttctg agcctgtttg
    12661 gcctctgcag gatttgacat ttgaatcagc cccactttga gccgtccacc tcctcccatc
    12721 atcccctgat cttagccaca tccagctcca agcagacatt ccaggcctcc ccatcccaac
    12781 aggctacata catgtccagc ctcaggaacg ctgccaaata caccaggcct cctcttgcca
    12841 cagcaccctt gcaaggaaca ctcaacttcc tgcccatcaa gcaatgccca ctccttgaag
    12901 acagtccaag catcactacc tgtaagcagc tttctctgat ccagacaggg ttaggtgcct
    12961 accctgctcc cacagcttcc tggaataggc ctgtcctcaa atgcatcact gtatatattt
    13021 actctcctat ctgcctaggc agactgagct cccagcatgg gatcccagca tggggtgagc
    13081 atgaaagagt ggcaaacaga gtggcataag acagataaaa tacaaaaggc aatttacaaa
    13141 ggaccaggac cgcagaggca gagataaacc agtgggctca gacttctgag cgtctcagat
    13201 ctggcgtcct cgactccctg aacctgcatc agggtcatgg gtcacagggg tgggggtggg
    13261 gtggagcggg gtacctggga cagcccaggg ctttggcata ccgcacggcc tgctccagtc
    13321 cctctcggaa ggccgcctgt ctcccgggga cggcccccag ccccatttcc cccttctctt
    13381 ggtctcctgc agagagaacg ggcctcagcc cccggctcgg acactcccct gcccgcgccc
    13441 cggcaccccc cagccctccc agccctcccg gcccgcgacg cacccggggg cgtgttgatc
    13501 agtacaagcc gcagccccgc ttctcgcgcg gcgcgcgcca gcgcctcagg cgtctccgcg
    13561 tacggccagg ccacctcgac ggcctcgaag cccgagctgc ccgcggcccg cacccgcgcg
    13621 gggaggccgg agagctcggg gaatagccag gacagattgg cggagaagcg cagcggcgcc
    13681 atgcctgggg aggccgggcc gggcggagtc cgcgggatcc aaaggcggcg ggcggcgggc
    13741 ggcgggcggc gggcgggggc ggggctctcc ttgctggccc tgcgaacgaa cgagcactgt
    13801 tcgtggttag aaaagcgaag tgctgtaaaa acccgggcct tcacgaaaag cgcctacggt
    13861 tagcgagaga gggatcacgg ggagaggcga aggggcggag cgagggcggc cggaaaagga
    13921 gcaggacccg cgcctggaga aggtagggag gccgagctcc agggcctgag agccggacgc
    13981 gaagcaagag agagctggct gcccgagggc ccggttgcaa tgatgggacg cgcactttaa
    14041 tactgagtct ttcctctgat tataaaaatg ctatctgttc gttaagcaac atttgaaagc
    14101 tgtatgacca aataaagaag cacttttata ccgcca
//
