LOCUS       NM_138780               4751 bp    mRNA    linear   PRI 10-OCT-2024
DEFINITION  Homo sapiens synaptotagmin like 5 (SYTL5), transcript variant 1,
            mRNA.
ACCESSION   NM_138780
VERSION     NM_138780.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4751)
  AUTHORS   Huang,D., Zeng,Y., Deng,H.Y., Fu,B.D., Ke,Y., Luo,J.Y., Yu,J.C. and
            Yu,S.T.
  TITLE     SYTL5 Promotes Papillary Thyroid Carcinoma Progression by Enhancing
            Activation of the NF-kappaB Signaling Pathway
  JOURNAL   Endocrinology 164 (1) (2022)
   PUBMED   36378561
  REMARK    GeneRIF: SYTL5 Promotes Papillary Thyroid Carcinoma Progression by
            Enhancing Activation of the NF-kappaB Signaling Pathway.
REFERENCE   2  (bases 1 to 4751)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 4751)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 4751)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 4751)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4751)
  AUTHORS   Wade,T.D., Gordon,S., Medland,S., Bulik,C.M., Heath,A.C.,
            Montgomery,G.W. and Martin,N.G.
  TITLE     Genetic variants associated with disordered eating
  JOURNAL   Int J Eat Disord 46 (6), 594-608 (2013)
   PUBMED   23568457
REFERENCE   7  (bases 1 to 4751)
  AUTHORS   Kerns,S.L., Ostrer,H., Stock,R., Li,W., Moore,J., Pearlman,A.,
            Campbell,C., Shao,Y., Stone,N., Kusnetz,L. and Rosenstein,B.S.
  TITLE     Genome-wide association study to identify single nucleotide
            polymorphisms (SNPs) associated with the development of erectile
            dysfunction in African-American men after radiotherapy for prostate
            cancer
  JOURNAL   Int J Radiat Oncol Biol Phys 78 (5), 1292-1300 (2010)
   PUBMED   20932654
REFERENCE   8  (bases 1 to 4751)
  AUTHORS   Colvin,R.A., Means,T.K., Diefenbach,T.J., Moita,L.F., Friday,R.P.,
            Sever,S., Campanella,G.S., Abrazinski,T., Manice,L.A., Moita,C.,
            Andrews,N.W., Wu,D., Hacohen,N. and Luster,A.D.
  TITLE     Synaptotagmin-mediated vesicle fusion regulates cell migration
  JOURNAL   Nat Immunol 11 (6), 495-502 (2010)
   PUBMED   20473299
REFERENCE   9  (bases 1 to 4751)
  AUTHORS   Saxena,S.K., Horiuchi,H. and Fukuda,M.
  TITLE     Rab27a regulates epithelial sodium channel (ENaC) activity through
            synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism
  JOURNAL   Biochem Biophys Res Commun 344 (2), 651-657 (2006)
   PUBMED   16630545
  REMARK    GeneRIF: These observations decisively prove that Rab27a inhibits
            ENaC function through a complex mechanism that involves GTP/GDP
            status, and protein-protein interactions involving Munc13-4 and
            SLP-5 effector proteins.
REFERENCE   10 (bases 1 to 4751)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     Synaptotagmin-like protein 5: a novel Rab27A effector with
            C-terminal tandem C2 domains
  JOURNAL   Biochem Biophys Res Commun 293 (3), 899-906 (2002)
   PUBMED   12051743
  REMARK    GeneRIF: molecular cloning of slp5:a novel Rab27A effector with
            C-terminal tandem C2 domains
            GeneRIF: Synaptotagmin-like protein 5 (Slp5) contains an N-terminal
            Slp homology domain (SHD) (PMID: 11327731). The SHD of Slp5
            specifically and directly binds the GTP-bound form of Rab27A.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL121578.1, BX647688.1,
            AK125106.1, AB080222.1 and AL135038.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_138780.2.
            
            Summary: The protein encoded by this gene belongs to the
            synaptotagmin-like (Slp) protein family, which contains a unique
            homology domain at the N-terminus, referred to as the Slp homology
            domain (SHD). The SHD functions as a binding site for Rab27A, which
            plays a role in protein transport. Expression of this gene is
            restricted to placenta and liver, suggesting that it might be
            involved in Rab27A-dependent membrane trafficking in specific
            tissues. Alternatively spliced transcript variants encoding
            different isoforms have been found for this gene. [provided by
            RefSeq, Sep 2009].
            
            Transcript Variant: This variant (1) encodes the shorter isoform
            (1). Variants 1 and 2 encode the same isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AB080222.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1968540, SAMEA2142348 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000297875.7/ ENSP00000297875.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AL121578.1         172873-172901
            30-77               BX647688.1         3-50
            78-1244             AK125106.1         18-1184
            1245-2665           AB080222.1         773-2193
            2666-4709           BX647688.1         2730-4773
            4710-4751           AL135038.1         162-203
FEATURES             Location/Qualifiers
     source          1..4751
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.4"
     gene            1..4751
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /note="synaptotagmin like 5"
                     /db_xref="GeneID:94122"
                     /db_xref="HGNC:HGNC:15589"
                     /db_xref="MIM:301126"
     exon            1..116
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            117..591
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     CDS             473..2665
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     exophilin 9; synaptotagmin-like protein 5"
                     /codon_start=1
                     /product="synaptotagmin-like protein 5 isoform 1"
                     /protein_id="NP_620135.1"
                     /db_xref="CCDS:CCDS14244.1"
                     /db_xref="GeneID:94122"
                     /db_xref="HGNC:HGNC:15589"
                     /db_xref="MIM:301126"
                     /translation="MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKN
                     ELLEAKRRSGKTQQEASRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWK
                     CTVCDKIAQLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTR
                     QDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQH
                     FRSLKSPPGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVIS
                     REYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFT
                     EDSEDTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSMM
                     SVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSY
                     LLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLG
                     EVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQ
                     LQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKAT
                     KHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSG
                     SGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL"
     exon            592..801
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            802..917
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1026
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1161
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1303
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1433
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1534
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1627
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1806
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1906
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2068
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2177
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2313
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2314..2522
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..4751
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4725..4730
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /note="hexamer: AATAAA"
     polyA_site      4751
                     /gene="SYTL5"
                     /gene_synonym="slp5"
                     /note="major polyA site"
ORIGIN      
        1 ggtttttcaa gttcctgctc caagtagttc acaagggtca agtagtccag cattctacag
       61 tttgtgtgtt tgagagaaaa ataagcccat aaaaacattc taaccttcag attaagtgtt
      121 ttctgcattc tctcccagcg gatctgattc ctgttctgaa gaattgaagt tgagcatcgt
      181 tagttaaatt cagctgctgc ctgactgtat accacagcaa aggctttgga aacatttttc
      241 agttaaaaca ataatgactt tcttggagtg taatcccagt ggaggctgtt ctacgtatag
      301 cctgaaagaa tacttaacta ccatacgcaa ttctgcagag accttgtaaa aatcacactt
      361 tacaccaaac aactgagtga ttctgaattg gttgggggaa tcttagttgt agatatcaat
      421 tcaccttctt gaagattcaa ccactgctac tcagagctgc tgctgaaata ccatgtctaa
      481 gaactcagag ttcatcaatc tgtcattttt attagatcat gagaaggaaa tgatcctggg
      541 cgtcctaaag agagatgaat atttgaaaaa agtggaggac aagagaataa ggaagctgaa
      601 aaatgaactc ttagaagcaa aacgtagaag tgggaaaact caacaagagg ccagcagagt
      661 ttgtgttcac tgtcacagaa acctgggcct aatctttgac cggggagacc cttgtcaggc
      721 ttgctcactg agggtatgca gggagtgtcg agttgcaggc cccaatggca gctggaagtg
      781 cactgtctgt gacaaaatcg cgcagctaag gattataact ggtgagtggt tttttgaaga
      841 aaaggcaaaa cgtttcaagc aagtcaatgt tctcggcact gatgttgtcc gacagtccat
      901 tttaagaaga agtccaggag ctgaagaagt acagagccaa gagcaaaccc gccaggatgc
      961 agaaaagtca gacacttcac ctgttgctgg gaagaaggcc agccatgatg ggcccaagag
     1021 aaagggattt cttcttagca agttcagatc ggcaaccaga ggagaaatca taactcccaa
     1081 aactgacact gggcggagct atagcttgga cttagacggt caacattttc ggagtttaaa
     1141 atcacctcct ggttcagaca ggggaagcac tggctcatca gatctcaatg accaggaacc
     1201 tggtcctagg accccgaaga gcagtcggag caatggtgtg accccaggca ctcagagttc
     1261 accagcccca agcacacgaa ctgtgacctc agtcatcagt agagagtatg gttttgaaaa
     1321 ttccatggat ttggctgcta ttgaaggtac ctctcaggag ctcacaaaga gtcaccgcag
     1381 aaacacttct ggcacacctt ccatagcagt gtctggaacc tctctctcct cagatcagag
     1441 tcgatctgag ttagatttga gtgagtcatt tacagaagac tcagaggata ctgtaagcat
     1501 aagaagcaag tctgtccctg gggctttaga caaggactcc ttggaagaga ctgaagaaag
     1561 cattgatgcc ttagtgtcct cgcagttatc tacaaacact caccgtctgg caagtggcct
     1621 atcaactacc agccttaaca gcatgatgag cgtttacagt gaaacgggag actatggcaa
     1681 cgtgaaagtc agtggtgaaa tccttctcca tatcagctac tgctacaaaa ctggtgggct
     1741 gtacattttt gtcaagaatt gcagaaatct ggccatagga gatgaaaaga aacagaggac
     1801 agatgcttat gtcaagtcat atcttcttcc tgacaagtcc cggaacaaca agcgtaagac
     1861 caaaatcaga acaggcacca atccagaatt caatgaaaca ctaaagtaca ctatcagcca
     1921 tacccagctg gaaacaagaa ctctgcagct ctcagtctgg cactatgatc gatttggacg
     1981 taatagcttc ctcggggaag tagagattcc ttttgactca tggaactttg aaaatccaac
     2041 tgatgagtgg tttgtgcttc aacccaaggt ggagtttgct cctgatattg gccttcaata
     2101 caaaggagag ctgacagttg ttttacgtta cattccccca gaagagaacc tgatgcttcc
     2161 accagaacaa ctccaaggaa ataagacttt taaaaaggga aagaagaagg agtcacctgt
     2221 aatctctgga ggaatactag aagtgttcat caaagaggca aagaatttga cagcagtgaa
     2281 gtcaggaggc acttctgata gctttgtgaa gggctacctg ctccctgatg atagcaaagc
     2341 caccaagcac aaaactctgg taataaaaaa gagtgttaac cctcagtgga atcatacatt
     2401 catgttcagt ggcatccatc cccaggatat aaagaatgtt tgcctagaac ttactatctg
     2461 ggacaaggag gccttttcca gcaacatctt tctgggagga gttcgtttga attctggaag
     2521 tggtgtgagc catgggaaga acgtggattg gatggactct cagggggaag agcagcgcct
     2581 ttggcagaag atggccaaca accctggaac tccctttgag ggtgtactca tgcttcgttc
     2641 cagcatggga aaatgtaggc tctaaaggga ccagttctcc aagaatgagg ccaccaggac
     2701 ctatctggct gtcttttcct accattagca aactgagacc tgggattctg cttccctgcc
     2761 atttctcacc tgacagtgtt gggacatgag gggagagatg tcagtagtat gaacatttag
     2821 ggtcttgctg agtgcctaaa aaacatatat ttccatccaa tcaaggcctt cttgattgga
     2881 tgatagaaag tgtactactt gtcctgtcaa caagcaaatt gtgcaaaggc ttatagggtt
     2941 tatgccataa aagaaatggc acaagcctcc atttgctaat tataagttac tttagatttc
     3001 ctcaaatcct ttgaagagaa agaggaccac tgagaaggta gatcacttga aaagtcagaa
     3061 gaaaggatac tggccaactt ttactcaccc taggaatcca catgatctca agaaggcatg
     3121 gtggagatgg ttgcttgagc aaggggattg tcctgttatt gcagcaaact tgtggattaa
     3181 ccaagtagta tttcaagatg gattgacagg gctttctatg attactatag aatttatcat
     3241 ctaaatcagt ttacttttta gaacaaagag agctaaataa ctacatcaga acgattgatg
     3301 ttgattagaa ttgacctggg aaaattggga tgtagggtca ccctactgat gacctaagag
     3361 agctctgttt taaacattta ttttataaaa tgttctaagc cattaactaa aaggaaatga
     3421 gatataatgg tcaattgata taccttttca cattgtgttc actgacgaga ctagtttaat
     3481 gaaaaaggag gtactctacc tgctatttta cttctgttcc tcttctgccc tgttatggga
     3541 gagaatcaaa gactccatct gctctcttcc cccttgtttt ctccttcact gagtttttct
     3601 tatctccttt tgcagtggtt aactattgtc acaataatgc tgaatgaaaa aacacaccaa
     3661 atgtcagtgg cttaaaatga ccatcctttt tctcacagtt atgaagattg gctatggcac
     3721 ctctgcttcc tgctataggc ctgaggttct agggcttctt atgcctcatc ctctttaagc
     3781 caaagggata gccagagcat cttgatggca gaagtgcaat aagatgagcc ccactgctcg
     3841 ggtacatttt cagcccctgg ttgtgtcatg tctactgata tctcattggt caaaggaagt
     3901 cagagggcca agatgaagag gcagggaaat atgcactgcc cacagtgaag ccatgacaag
     3961 agtgaggatg caggaaggca tgaagaattg gggccaacag ttcaatctac cataccttct
     4021 ctcacctgga attccagatg cttgagctac gaaacttaga tgcaaagaaa gttaaagcta
     4081 gaaggaacct caggcccagt tgctcatttt gcagattcca aatgtgaatt tcagagagct
     4141 gagataactt gcccaaggcc atatagaggc tgtgactaaa tctggactta aatccagact
     4201 atcaatctta ggccagtgtt cttttttcaa tatagtcctt ggcataatgc tatgcttatt
     4261 aggtagataa aagggcttat gtcaagaaat ttggagcaga gtctgattac ttgagcatga
     4321 acatacccga ccaaggtatg ttctggagtc atattctagc ctctgagctc attttttcat
     4381 gcgagttcat ataaaatcct cgaaagttta gaaactaggt tttagtagta acggagctag
     4441 aatcatcttc gggcttattc ctgctagttg ttccatattt ctagatttca tcttgaattt
     4501 tgaaaactga tttaagaata tatttagtat tattattagt aagggaatac gcaatccagt
     4561 ttcaatttta ttcagaagta ggtcacctaa ttctagaaaa tggttattag tctagtgtcg
     4621 cttagcaagg tacttaaaag aaaatctgca catatccttg tgctgccctt cttaaaaaca
     4681 gaaaacaaaa agtgtaagat catcattgct tcccacatag gaaaaataaa atgtcttcag
     4741 acttgatgtg a
//
