LOCUS       NM_001105579            2709 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens synapse differentiation inducing 1 like (SYNDIG1L),
            mRNA.
ACCESSION   NM_001105579 XM_929601 XM_938515
VERSION     NM_001105579.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2709)
  AUTHORS   Sallman Almen,M., Bringeland,N., Fredriksson,R. and Schioth,H.B.
  TITLE     The dispanins: a novel gene family of ancient origin that contains
            14 human members
  JOURNAL   PLoS One 7 (2), e31961 (2012)
   PUBMED   22363774
REFERENCE   2  (bases 1 to 2709)
  AUTHORS   de Chaldee,M., Brochier,C., Van de Vel,A., Caudy,N.,
            Luthi-Carter,R., Gaillard,M.C. and Elalouf,J.M.
  TITLE     Capucin: a novel striatal marker down-regulated in rodent models of
            Huntington disease
  JOURNAL   Genomics 87 (2), 200-207 (2006)
   PUBMED   16359841
  REMARK    GeneRIF: Cloning and characterization of the TMEM90A (capucin)
            ortholog in mouse.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005479.2, DB473943.1, DB173128.1 and CK906042.1.
            
            On Nov 24, 2018 this sequence version replaced NM_001105579.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.212328.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465403, SAMN03465404
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000331628.8/ ENSP00000331474.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               AC005479.2         108717-108824
            109-302             DB473943.1         2-195
            303-623             AC005479.2         125129-125449
            624-1186            DB173128.1         8-570
            1187-2385           AC005479.2         127506-128704
            2386-2709           CK906042.1         29-352              c
FEATURES             Location/Qualifiers
     source          1..2709
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..2709
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /note="synapse differentiation inducing 1 like"
                     /db_xref="GeneID:646658"
                     /db_xref="HGNC:HGNC:32388"
                     /db_xref="MIM:609999"
     exon            1..299
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /inference="alignment:Splign:2.1.0"
     exon            300..773
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /inference="alignment:Splign:2.1.0"
     CDS             357..1073
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /note="transmembrane protein 90A; interferon induced
                     transmembrane protein domain containing 4; caudate- and
                     putamen-enriched sequence; dispanin subfamily C member 1"
                     /codon_start=1
                     /product="synapse differentiation-inducing gene protein
                     1-like"
                     /protein_id="NP_001099049.1"
                     /db_xref="CCDS:CCDS41970.1"
                     /db_xref="GeneID:646658"
                     /db_xref="HGNC:HGNC:32388"
                     /db_xref="MIM:609999"
                     /translation="MESLSELQNPLLPRSPAHLHGPYPYPETPPSWSCQEKLYSYLLG
                     GAGPAGAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPRAGSCETSFTEDREPQEGPP
                     EQPTGPGQAAENVTIQTVSYGVQEELRDQEDDQEEEESDATSTESESEDNFLTLPPRD
                     HLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVGA
                     GLYVAVVVALAAYMSQNGHG"
     exon            774..914
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /inference="alignment:Splign:2.1.0"
     exon            915..2709
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2691..2696
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /note="hexamer: AATAAA"
     polyA_site      2709
                     /gene="SYNDIG1L"
                     /gene_synonym="CAPUCIN; DSPC1; IFITMD4; SynDIG2; TMEM90A"
                     /note="major polyA site"
ORIGIN      
        1 aagtcggcgc ggagccgcct cgggccgggc cgagggctgc gcggcggcgg cggcggcggg
       61 gcccggccag gatgcggggc tcccgggacc gcgcggggcg gggcgggcgg cggcggcggg
      121 ctgcgggcgg gagctgtccg cggtgctgaa gcggcggctg ctcagggacg cggggacgag
      181 agcaggggag ccctcctggg agttccaccg cgaccgcgag gcgggggcgc cgtcgctcac
      241 cggcccatgc cgagcccccg agccccgcgg aggaggcggg accgtccgcg gcgggacagg
      301 ctctgaggac tgctcagctg gcccaggccc ccctccccag cagctgcccc agaaccatgg
      361 agagtctgag tgaactacag aacccgctgc tgcccaggag ccctgcccat ctccatggcc
      421 cctatcccta cccggagacc ccacccagct ggtcctgcca ggaaaagctc tactcctacc
      481 tcctaggtgg cgctgggcct gccggagccc accagctcct ggacccaggg tccctgcagc
      541 tggccgtgga ggcctggtac cggcccagct gcctcctggg gagagacaag gtcaaggagc
      601 ccagggcagg cagctgtgag acaagcttca cagaggacag ggagccccag gaggggcctc
      661 cagagcagcc cacaggacct ggccaagctg cagagaatgt caccatccag actgtgtcct
      721 atggggtaca agaggagctg cgggaccagg aggatgacca ggaggaagag gagagcgatg
      781 ccacttcaac ggagagtgaa agtgaagaca acttcctcac gctgcctccc agggaccacc
      841 tgggacttac tctcttctcc atgctctgct gcttctggcc actgggcatt gctgccttct
      901 acttctccca ggggaccagc aaggccatct ccaaagggga cttccgcctg gccagcacca
      961 cctcccgccg ggccctcttc ctagccacac tcgccatcgc cgtgggggcc ggtctctacg
     1021 tggctgtggt ggtggctctg gcagcttaca tgtcccagaa cggtcatggc tagtagccag
     1081 tagggcctgc atcctgactc ccctgcccac ctgaggaagc agtggggctt ggagttgcag
     1141 accctatgga aaggcccggc ccctgaagat gatcccgtga gagtggcttg ctgaggggga
     1201 gacccccatt ccacagcctg cagagctcag ccttcacttc tgcttgcccg ctgctcccag
     1261 ccccagagca gggcccgggg cgccactctc taacccaggc tacagacggg aaacagaagg
     1321 cagggctgcc caccaggcca tcccagcagg gcctagctcc atccattctg cccattccct
     1381 agaggatctc ctgccctaca gccagcccac cacctaccct gccaacctcc ccacagagaa
     1441 agagcaggag gttacaggga gaaaaggggg tgcccagagc acaaggggac ccgtcccaat
     1501 cctttcagcc cacagggatc ttcacctggg gacagcctga gcttccccca actccactgt
     1561 ctggccccat catgcccaga cctcagcagg ccaagaagga aatacgtgga ggcaaggggg
     1621 cctcttgctg tctctgattc tagagggtgc ttatctctgc atgggcttgt gaggcactgt
     1681 agattctaga tagggaagag gagcctcggt atgtaaactc tgaaccaagg gcaggttctt
     1741 ggagcttctt catgcgggtg caaaaggcag ttgcaatgac agagaataga gggtcctgaa
     1801 atattgctgt actacatgac tcttcctact ctccccccac tccccgcccc tatcatcctt
     1861 ttctgggctt tgcctggggg tccgtgagct ggtgccatca caagtagact agacccagag
     1921 agtgccctca gctcaccagc cactgagcgc acggccctag gtccagccct acagaaaacg
     1981 cagcaaggag agaccctagg gagtagtgag tatagatgag ggaagggact cagggaagga
     2041 atggcctgct gagtagtcag cggtgcttag gaaggcttcc tggaggaggt atcccttgag
     2101 caagtcctag gatgaataga attcatctaa gggatttggt cacataactc tttgtatttg
     2161 taggcaggga tgtggcagga accttccatg ggaagcttcc aggctgtttg gattctgcct
     2221 ggaacatctg ggctggagcc aaactacagc cattcctaag ggttctgcca actcaaggag
     2281 gaacgtcaca cctgtctctc aaagaccaat gatgttttcc catctctgaa tgctaggggg
     2341 tcagtggtgg gtacctggtt acccctgggg catcttcact gatatctctg ctcagtgcca
     2401 gtctcaacac cctcagccac tagggcacat ccagaatttt agagacatct ccaggtaggc
     2461 ggggggcagc accaatgtgg gcaggcctgt ctggactcaa gctacaggcc cctgctgtgc
     2521 atgatgtggg aacctggtca ttcccatgcc ccatccagag cccagggctg tggctccacc
     2581 actgagcatc ccttgtccca ctgtcctccc ctgcctcggg cactgcccag ccctccactc
     2641 ctgcatcaca gcagttttaa ggtcccatta ttgtactgat ttatccttgt aataaatgtt
     2701 tctgtaaca
//
