LOCUS       NM_001040274            2909 bp    mRNA    linear   PRI 31-MAY-2024
DEFINITION  Homo sapiens synaptonemal complex protein 2 like (SYCP2L), mRNA.
ACCESSION   NM_001040274
VERSION     NM_001040274.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Rosa,I.R., Barbosa,C.P., Ferrandez,C.A., Sonoda,B.D.B.,
            Christofolini,D.M., Trevisan,C.M., Lagana,A.S., Peluso,C. and
            Bianco,B.
  TITLE     Involvement of SYCP2L and TDRD3 gene variants on ovarian reserve
            and reproductive outcomes: a cross-sectional study
  JOURNAL   JBRA Assist Reprod 27 (3), 428-435 (2023)
   PUBMED   37417852
  REMARK    GeneRIF: Involvement of SYCP2L and TDRD3 gene variants on ovarian
            reserve and reproductive outcomes: a cross-sectional study.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  AUTHORS   He,W.B., Tan,C., Zhang,Y.X., Meng,L.L., Gong,F., Lu,G.X., Lin,G.,
            Du,J. and Tan,Y.Q.
  TITLE     Homozygous variants in SYCP2L cause premature ovarian insufficiency
  JOURNAL   J Med Genet 58 (3), 168-172 (2021)
   PUBMED   32303603
  REMARK    GeneRIF: Homozygous variants in SYCP2L cause premature ovarian
            insufficiency.
REFERENCE   3  (bases 1 to 2909)
  AUTHORS   Zhou,J., Stein,P., Leu,N.A., Chmatal,L., Xue,J., Ma,J., Huang,X.,
            Lampson,M.A., Schultz,R.M. and Wang,P.J.
  TITLE     Accelerated reproductive aging in females lacking a novel
            centromere protein SYCP2L
  JOURNAL   Hum Mol Genet 24 (22), 6505-6514 (2015)
   PUBMED   26362258
  REMARK    GeneRIF: We find that a human SYCP2L intronic single nucleotide
            polymorphism (SNP) rs2153157, which is associated with ANM, changes
            the splicing efficiency of U12-type minor introns
REFERENCE   4  (bases 1 to 2909)
  AUTHORS   Bunyavanich,S., Schadt,E.E., Himes,B.E., Lasky-Su,J., Qiu,W.,
            Lazarus,R., Ziniti,J.P., Cohain,A., Linderman,M., Torgerson,D.G.,
            Eng,C.S., Pino-Yanes,M., Padhukasahasram,B., Yang,J.J.,
            Mathias,R.A., Beaty,T.H., Li,X., Graves,P., Romieu,I., Navarro
            Bdel,R., Salam,M.T., Vora,H., Nicolae,D.L., Ober,C., Martinez,F.D.,
            Bleecker,E.R., Meyers,D.A., Gauderman,W.J., Gilliland,F.,
            Burchard,E.G., Barnes,K.C., Williams,L.K., London,S.J., Zhang,B.,
            Raby,B.A. and Weiss,S.T.
  TITLE     Integrated genome-wide association, coexpression network, and
            expression single nucleotide polymorphism analysis identifies novel
            pathway in allergic rhinitis
  JOURNAL   BMC Med Genomics 7, 48 (2014)
   PUBMED   25085501
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2909)
  AUTHORS   Seppala,I., Kleber,M.E., Lyytikainen,L.P., Hernesniemi,J.A.,
            Makela,K.M., Oksala,N., Laaksonen,R., Pilz,S., Tomaschitz,A.,
            Silbernagel,G., Boehm,B.O., Grammer,T.B., Koskinen,T., Juonala,M.,
            Hutri-Kahonen,N., Alfthan,G., Viikari,J.S., Kahonen,M.,
            Raitakari,O.T., Marz,W., Meinitzer,A. and Lehtimaki,T.
  CONSRTM   AtheroRemo Consortium
  TITLE     Genome-wide association study on dimethylarginines reveals novel
            AGXT2 variants associated with heart rate variability but not with
            overall mortality
  JOURNAL   Eur Heart J 35 (8), 524-531 (2014)
   PUBMED   24159190
REFERENCE   6  (bases 1 to 2909)
  AUTHORS   Stolk,L., Perry,J.R., Chasman,D.I., He,C., Mangino,M., Sulem,P.,
            Barbalic,M., Broer,L., Byrne,E.M., Ernst,F., Esko,T.,
            Franceschini,N., Gudbjartsson,D.F., Hottenga,J.J., Kraft,P.,
            McArdle,P.F., Porcu,E., Shin,S.Y., Smith,A.V., van Wingerden,S.,
            Zhai,G., Zhuang,W.V., Albrecht,E., Alizadeh,B.Z., Aspelund,T.,
            Bandinelli,S., Lauc,L.B., Beckmann,J.S., Boban,M., Boerwinkle,E.,
            Broekmans,F.J., Burri,A., Campbell,H., Chanock,S.J., Chen,C.,
            Cornelis,M.C., Corre,T., Coviello,A.D., d'Adamo,P., Davies,G., de
            Faire,U., de Geus,E.J., Deary,I.J., Dedoussis,G.V., Deloukas,P.,
            Ebrahim,S., Eiriksdottir,G., Emilsson,V., Eriksson,J.G.,
            Fauser,B.C., Ferreli,L., Ferrucci,L., Fischer,K., Folsom,A.R.,
            Garcia,M.E., Gasparini,P., Gieger,C., Glazer,N., Grobbee,D.E.,
            Hall,P., Haller,T., Hankinson,S.E., Hass,M., Hayward,C.,
            Heath,A.C., Hofman,A., Ingelsson,E., Janssens,A.C., Johnson,A.D.,
            Karasik,D., Kardia,S.L., Keyzer,J., Kiel,D.P., Kolcic,I.,
            Kutalik,Z., Lahti,J., Lai,S., Laisk,T., Laven,J.S., Lawlor,D.A.,
            Liu,J., Lopez,L.M., Louwers,Y.V., Magnusson,P.K., Marongiu,M.,
            Martin,N.G., Klaric,I.M., Masciullo,C., McKnight,B., Medland,S.E.,
            Melzer,D., Mooser,V., Navarro,P., Newman,A.B., Nyholt,D.R.,
            Onland-Moret,N.C., Palotie,A., Pare,G., Parker,A.N., Pedersen,N.L.,
            Peeters,P.H., Pistis,G., Plump,A.S., Polasek,O., Pop,V.J.,
            Psaty,B.M., Raikkonen,K., Rehnberg,E., Rotter,J.I., Rudan,I.,
            Sala,C., Salumets,A., Scuteri,A., Singleton,A., Smith,J.A.,
            Snieder,H., Soranzo,N., Stacey,S.N., Starr,J.M., Stathopoulou,M.G.,
            Stirrups,K., Stolk,R.P., Styrkarsdottir,U., Sun,Y.V., Tenesa,A.,
            Thorand,B., Toniolo,D., Tryggvadottir,L., Tsui,K., Ulivi,S., van
            Dam,R.M., van der Schouw,Y.T., van Gils,C.H., van Nierop,P.,
            Vink,J.M., Visscher,P.M., Voorhuis,M., Waeber,G., Wallaschofski,H.,
            Wichmann,H.E., Widen,E., Wijnands-van Gent,C.J., Willemsen,G.,
            Wilson,J.F., Wolffenbuttel,B.H., Wright,A.F.,
            Yerges-Armstrong,L.M., Zemunik,T., Zgaga,L., Zillikens,M.C.,
            Zygmunt,M., Arnold,A.M., Boomsma,D.I., Buring,J.E., Crisponi,L.,
            Demerath,E.W., Gudnason,V., Harris,T.B., Hu,F.B., Hunter,D.J.,
            Launer,L.J., Metspalu,A., Montgomery,G.W., Oostra,B.A.,
            Ridker,P.M., Sanna,S., Schlessinger,D., Spector,T.D.,
            Stefansson,K., Streeten,E.A., Thorsteinsdottir,U., Uda,M.,
            Uitterlinden,A.G., van Duijn,C.M., Volzke,H., Murray,A.,
            Murabito,J.M., Visser,J.A. and Lunetta,K.L.
  CONSRTM   LifeLines Cohort Study
  TITLE     Meta-analyses identify 13 loci associated with age at menopause and
            highlight DNA repair and immune pathways
  JOURNAL   Nat Genet 44 (3), 260-268 (2012)
   PUBMED   22267201
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2909)
  AUTHORS   Lemaitre,R.N., Tanaka,T., Tang,W., Manichaikul,A., Foy,M.,
            Kabagambe,E.K., Nettleton,J.A., King,I.B., Weng,L.C.,
            Bhattacharya,S., Bandinelli,S., Bis,J.C., Rich,S.S., Jacobs,D.R.
            Jr., Cherubini,A., McKnight,B., Liang,S., Gu,X., Rice,K.,
            Laurie,C.C., Lumley,T., Browning,B.L., Psaty,B.M., Chen,Y.D.,
            Friedlander,Y., Djousse,L., Wu,J.H., Siscovick,D.S.,
            Uitterlinden,A.G., Arnett,D.K., Ferrucci,L., Fornage,M., Tsai,M.Y.,
            Mozaffarian,D. and Steffen,L.M.
  TITLE     Genetic loci associated with plasma phospholipid n-3 fatty acids: a
            meta-analysis of genome-wide association studies from the CHARGE
            Consortium
  JOURNAL   PLoS Genet 7 (7), e1002193 (2011)
   PUBMED   21829377
REFERENCE   8  (bases 1 to 2909)
  AUTHORS   He,C., Kraft,P., Chen,C., Buring,J.E., Pare,G., Hankinson,S.E.,
            Chanock,S.J., Ridker,P.M., Hunter,D.J. and Chasman,D.I.
  TITLE     Genome-wide association studies identify loci associated with age
            at menarche and age at natural menopause
  JOURNAL   Nat Genet 41 (6), 724-728 (2009)
   PUBMED   19448621
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB077181.1, AM293674.1, AL357497.17, AK294018.1 and AI027433.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001040274.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AM293674.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000283141.11/ ENSP00000283141.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                DB077181.1         222-282
            62-119              AM293674.1         2-59
            120-120             AL357497.17        15647-15647
            121-714             AM293674.1         61-654
            715-1387            AK294018.1         863-1535
            1388-2088           AM293674.1         1328-2028
            2089-2089           AL357497.17        79274-79274
            2090-2825           AM293674.1         2030-2765
            2826-2909           AI027433.1         10-93               c
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p24.2"
     gene            1..2909
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="synaptonemal complex protein 2 like"
                     /db_xref="GeneID:221711"
                     /db_xref="HGNC:HGNC:21537"
                     /db_xref="MIM:616799"
     exon            1..84
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..2514
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="SCP-2-like; 145 kDa nucleolar protein homolog"
                     /codon_start=1
                     /product="synaptonemal complex protein 2-like"
                     /protein_id="NP_001035364.2"
                     /db_xref="CCDS:CCDS43423.1"
                     /db_xref="GeneID:221711"
                     /db_xref="HGNC:HGNC:21537"
                     /db_xref="MIM:616799"
                     /translation="MQAKNKDALQPIKEDRTGKAQDDAFWLQSLITDAFHDKGFQKIK
                     EYFQQKESHFPQKYNRLLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDGLKEDEP
                     LLIRQGLIPKLVSWFERTTGILTSEGLASDTSLICVIEDFFDTALIISRSSSEGKIQM
                     LDSFLLSLGFLVTEKTVNHLLQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKDLA
                     RTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSR
                     RFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWIDFNLGSQSVTFYID
                     NAENTLWDSVTLPKEAVMNFSITETEKIKIFIIYLKKPMIISYKEVMKIEIHFDLQFN
                     ISQVSIQALGEDKQMLPDQTKISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFM
                     SAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSES
                     NQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS
                     PSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDE
                     EKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVAPGSPFSITEER
                     ELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAPDC
                     LIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEFWGKQSADLQSF
                     CDLQVLRFNSTQTS"
     exon            85..153
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            154..291
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            292..411
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            412..516
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            517..541
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            542..627
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            628..716
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            717..751
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            752..894
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            895..947
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            948..993
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1086
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1147
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1293
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1387
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1515
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1563
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1708
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1758
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1759..1888
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..1959
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2029
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2131
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2238
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2330
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2331..2430
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2489
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2551
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     exon            2552..2909
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2775..2780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="hexamer: AATAGA"
     polyA_site      2800
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="major polyA site"
     regulatory      2831..2836
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="hexamer: AGTAAA"
     polyA_site      2856
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="major polyA site"
     regulatory      2880..2885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
                     /note="hexamer: AATAAA"
     polyA_site      2909
                     /gene="SYCP2L"
                     /gene_synonym="C6orf177; dJ62D2.1; NO145; POF24"
ORIGIN      
        1 ggggaagcag gagagggccg accgagcgca acaaagctga gcggcgcgtc gcttcaggaa
       61 cgaagaagcc tcgttatgca agcgaaaaac aaagatgctt tgcagcctat taaggaagac
      121 aggactggga aggcccagga tgatgctttc tggcttcaat cacttattac ggatgcattc
      181 catgataaag gatttcagaa aataaaagaa tactttcaac agaaagagag ccactttcct
      241 caaaaatata atcgtcttct attataccgt cttgacagat caataaataa ggaactagat
      301 aaaaatgaat ttcagtctgt gtcactgttg ctgaaatgta ttcagcgatt cctcgtagat
      361 ggcctgaaag aagatgaacc tctgctaatt cggcagggac tgatcccaaa gctagtttcc
      421 tggtttgaaa gaacaacagg aattctgacc tcggaaggcc tagcctcaga cacgtcgctg
      481 atttgtgtta tagaagattt ctttgacact gcattgatta tttccaggag tagtagtgaa
      541 gggaaaattc agatgttgga ttccttccta cttagcttag gattcctggt gacagaaaag
      601 actgtaaatc atttgcttca acaggagggc ttgaagactt ttaactgcat tttgcacgct
      661 gtccctcgag aagagagaaa aaaattccct ttgtcagaag gcatgtgtca tcttatgaaa
      721 gaccttgcaa ggacactctt gactgtgggt gattatgacc agcaggttgc tatttctgaa
      781 gcgctgtgta gactgacgat taaaaaatca agggatgaac ttgtccataa atggtttgat
      841 gatgaagtca ttgctgaagc tttcaaagaa attaaggatc gagaatttga gacggacagt
      901 agacgttttc tcaatcacct aaacaacaga cttggtgacc aaagaagggt gtattcattt
      961 ccgtgtattg ctgcttttgc tgatgagcat gagatgagaa aaccagcgga tgaaaaatta
     1021 gagaaatttt ggatcgactt caacctagga agtcagagtg tcacttttta tatagacaat
     1081 gctgagaata ctctatggga ctcagtgaca cttccgaagg aagcggtgat gaatttcagc
     1141 ataacagaaa cggagaagat aaagatattt atcatttacc tgaagaagcc catgattatc
     1201 agctacaaag aagtcatgaa aatagaaatc cattttgatt tgcagttcaa catatcacaa
     1261 gtttccattc aagctttagg agaagacaaa cagatgttgc ctgaccagac gaaaatctcc
     1321 tcagaacttt ttagtaagtc tgataaagaa gacagggaga gtcccagtgg ccttgaaaga
     1381 gaaacagagc aggcagaaga atccactaac atggtggagt ttatgagtgc tgaagatgac
     1441 cgctgcctaa taactctcca cttaaatgac caatctgagc cacctgttat tggggaacct
     1501 gcctctgata gtcaccttca gccggtccct ccgttcgggg tccctgactt cccgcaacaa
     1561 cctaagtctc attacagaaa acatctcttc tctgagagta atcaagattc aagtaccagt
     1621 gaactatctt ggaccagtaa ccagaaaaag aaatccctaa aatcatattc cagtagaaag
     1681 aagacaagaa ccagaagtaa tttgagaatc ttgccagttt tccctcccag tagtggcagt
     1741 ggccatgaga aagaccaagc taagcttcta tcaccatcag agaaagaaat acccgagcaa
     1801 aataacacca catctccaaa gacttctgaa caaaaattcc aagatagttt tgcttttttg
     1861 actgctgaag attctgccca gaaaacagag cttcaagatc ctcactcact gagtgagctc
     1921 tcttccttga agcactcaga agatgaagaa aaacctaaga ttgtgaacca agaatcacta
     1981 acagaaagta ctagcttgaa acataagctg agaaacttgg aagacaaaga cataccagaa
     2041 ggtagttttg ctaagtcaca acaatcaaga ttggaagaag aggttgctcc gggatcccct
     2101 ttctcaataa cagaagaaag agagttgcca gaaggaattt ccacttcatc cctagaagtt
     2161 gtgccagaga acttgaacgg ttctgccatt ctcccaacct ttgaaaactt cactaaaaaa
     2221 cggaaaagaa aatatgagct taggtacaga aagcgtccgt ttaattcaga aaatgcaaag
     2281 aaagcaccgg attgcctaat aaaactttta aaccagatgc aactgttcag actcaataaa
     2341 ctagagcgct ttcaaaattt ggttcttcaa gagttgagca gtcttaagca ggatattcag
     2401 gccctggaac accttgagaa ggaggttctg gaattctggg ggaaacagtc tgctgatctg
     2461 caatctttct gtgatctgca agtgctgagg ttcaattcaa ctcagacttc ataagaaagc
     2521 caaagcctgg ttttatgatt gcagccctca gcctgggctg cctgaagacg aagagaaaga
     2581 gcaaggttat tgttggctca ggccttgtta gccagacttc gtgctctgta cgcattcaat
     2641 ttcctcccct ccaaacatca tccctgggaa ctgctgagtt cagatagaat atatgttggt
     2701 agtttgcagt tgggttatta tccatttgtt cataaaaatt aaccttttgt attaaaattt
     2761 ggtcagatag tattaataga aagttcagga tgttaaacaa cttggagtgg tgttgctttt
     2821 tttttataaa agtaaaatgg actttttttt gtttgagaaa tgtcttcaag ttttgtgtga
     2881 ataaaacact ttagcagcat ctgtataaa
//
