LOCUS       NM_001129979            1057 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens synaptonemal complex central element protein 1 like
            (SYCE1L), transcript variant 1, mRNA.
ACCESSION   NM_001129979 XM_001719609
VERSION     NM_001129979.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1057)
  AUTHORS   Gu,S., Hu,J., Song,P., Gong,W. and Guo,M.
  TITLE     Identification of a new transcript specifically expressed in mouse
            spermatocytes: mmrp2
  JOURNAL   Mol Biol Rep 32 (4), 247-255 (2005)
   PUBMED   16328886
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009139.8.
            
            On May 17, 2019 this sequence version replaced NM_001129979.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2145893 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378644.5/ ENSP00000367911.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AC009139.8         54248-54352
            106-165             AC009139.8         61281-61340
            166-225             AC009139.8         63050-63109
            226-300             AC009139.8         63305-63379
            301-348             AC009139.8         63937-63984
            349-403             AC009139.8         64257-64311
            404-467             AC009139.8         66053-66116
            468-537             AC009139.8         66970-67039
            538-625             AC009139.8         67122-67209
            626-698             AC009139.8         67414-67486
            699-1057            AC009139.8         67697-68055
FEATURES             Location/Qualifiers
     source          1..1057
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q23.1"
     gene            1..1057
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /note="synaptonemal complex central element protein 1
                     like"
                     /db_xref="GeneID:100130958"
                     /db_xref="HGNC:HGNC:37236"
                     /db_xref="MIM:619954"
     exon            1..105
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..773
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     meiosis-related protein"
                     /codon_start=1
                     /product="synaptonemal complex central element protein
                     1-like isoform 1"
                     /protein_id="NP_001123451.1"
                     /db_xref="CCDS:CCDS45533.1"
                     /db_xref="GeneID:100130958"
                     /db_xref="HGNC:HGNC:37236"
                     /db_xref="MIM:619954"
                     /translation="MAGKLKPLNVEAPEATEEAEGQAKSLKTEDLLAMVIKLQKEGSL
                     EPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKVHLEEVLGKKQE
                     ALRILQMHCQEKESEAQRLDVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQ
                     LLSERRLVRAKLREVERRLHSPPEVEGAMAVNDGLKAELEIFGEQVRSAPEVGAGEGE
                     AGPELPRARDEEDPEPPVAAPDAL"
     exon            106..165
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            166..225
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            226..300
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            301..348
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            349..403
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            404..467
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            468..537
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            538..625
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            626..698
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            699..1057
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      822..827
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /note="hexamer: AATAAA"
     polyA_site      845
                     /gene="SYCE1L"
                     /gene_synonym="MRP2"
                     /note="major polyA site"
ORIGIN      
        1 accagtcatc aagcgaggct cgcgcgcagg ccccgcgttg gaaaatggcg gggaagctga
       61 aacctctgaa tgtggaggcg ccagaagcta ctgaggaggc tgaagggcaa gccaagtctt
      121 tgaagactga agacttgctg gcaatggtga taaagctgca gaaagaggga agcctggagc
      181 cacagataga ggacctgatt agccggatta atgatcttca gcaagcaaag aagaaatcca
      241 gtgaggaact gagagagacc cacagtctct gggaggccct gcatagggaa ttagactcct
      301 tgaatggaga gaaagtgcac ctagaggagg tcttgggcaa aaagcaagag gcactgagga
      361 tcctccagat gcactgccaa gagaaggaaa gcgaggctca gaggttggat gtcagaggac
      421 agctggagga tctgatgggc cagcacaagg acctctggga attccacatg ctggagcagc
      481 gactggcccg ggagatccgt gccctggaga gaagcaagga gcagctgctc tcggagagga
      541 ggctggtgcg cgccaagctg cgggaggtgg agcggcggct gcactcgccg cctgaggtcg
      601 agggcgccat ggcggtgaat gacgggctga aggcggagct ggagatattc ggggagcagg
      661 tccggagcgc ccccgaggtc ggggccggcg agggagaggc cggacctgag ctcccccgcg
      721 ctcgcgacga ggaggatccc gagccgccgg tggctgcccc tgacgccctc taggccagca
      781 ggacccgccc gttcccgacc ttccctcgag acccgccaag aaataaaggc gatgatttcc
      841 gaccatgctc gcgttctccg cggagtctgt gctacaccgt ggagcggggc ggggcgtgct
      901 gggatctcga ggcggggcct ctgccggacc cctcccacca gtcgagcccc gggcgccgta
      961 cagaggctgg gtaaatgctc ctgaactcag agagagtaag tgggtgtcag tatcccccgc
     1021 cccacggcct catctcgagt tcccaaacca tctatgt
//
