LOCUS       NM_001014286            2923 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens SPT20 homolog, SAGA complex component (SUPT20H),
            transcript variant 1, mRNA.
ACCESSION   NM_001014286
VERSION     NM_001014286.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2923)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 2923)
  AUTHORS   Arata,Y., Watanabe,A., Motosugi,R., Iemura,S.I., Natsume,T.,
            Mukai,K., Taguchi,T., Hirayama,S., Hamazaki,J. and Murata,S.
  TITLE     FAM48A mediates compensatory autophagy induced by proteasome
            impairment
  JOURNAL   Genes Cells 24 (8), 559-568 (2019)
   PUBMED   31210371
  REMARK    GeneRIF: Our results indicate that FAM48A is a kind of sensor that
            is required for compensatory autophagy induction upon proteasome
            impairment.
REFERENCE   3  (bases 1 to 2923)
  AUTHORS   Lin,Y., Mallen-St Clair,J., Wang,G., Luo,J., Palma-Diaz,F., Lai,C.,
            Elashoff,D.A., Sharma,S., Dubinett,S.M. and St John,M.
  TITLE     p38 MAPK mediates epithelial-mesenchymal transition by regulating
            p38IP and Snail in head and neck squamous cell carcinoma
  JOURNAL   Oral Oncol 60, 81-89 (2016)
   PUBMED   27531877
  REMARK    GeneRIF: provide the first report that p38-p38IP is required for
            the Snail-induced E-cadherin down-regulation and cell invasion in
            HNSCC
REFERENCE   4  (bases 1 to 2923)
  AUTHORS   Liu,X., Xiao,W., Wang,X.D., Li,Y.F., Han,J. and Li,Y.
  TITLE     The p38-interacting protein (p38IP) regulates G2/M progression by
            promoting alpha-tubulin acetylation via inhibiting
            ubiquitination-induced degradation of the acetyltransferase GCN5
  JOURNAL   J Biol Chem 288 (51), 36648-36661 (2013)
   PUBMED   24220028
  REMARK    GeneRIF: p38IP inhibits ubiquitination-induced GCN5 degradation and
            therefore promotes alpha-tubulin acetylation, facilitating spindle
            formation and G2/M progression.
REFERENCE   5  (bases 1 to 2923)
  AUTHORS   Wang,J., Huo,K., Ma,L., Tang,L., Li,D., Huang,X., Yuan,Y., Li,C.,
            Wang,W., Guan,W., Chen,H., Jin,C., Wei,J., Zhang,W., Yang,Y.,
            Liu,Q., Zhou,Y., Zhang,C., Wu,Z., Xu,W., Zhang,Y., Liu,T., Yu,D.,
            Zhang,Y., Chen,L., Zhu,D., Zhong,X., Kang,L., Gan,X., Yu,X., Ma,Q.,
            Yan,J., Zhou,L., Liu,Z., Zhu,Y., Zhou,T., He,F. and Yang,X.
  TITLE     Toward an understanding of the protein interaction network of the
            human liver
  JOURNAL   Mol Syst Biol 7, 536 (2011)
   PUBMED   21988832
  REMARK    Erratum:[Mol Syst Biol. 2017 Dec 18;13(12):965. doi:
            10.15252/msb.20178107.. PMID: 29254952]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2923)
  AUTHORS   Wan,D., Gong,Y., Qin,W., Zhang,P., Li,J., Wei,L., Zhou,X., Li,H.,
            Qiu,X., Zhong,F., He,L., Yu,J., Yao,G., Jiang,H., Qian,L., Yu,Y.,
            Shu,H., Chen,X., Xu,H., Guo,M., Pan,Z., Chen,Y., Ge,C., Yang,S. and
            Gu,J.
  TITLE     Large-scale cDNA transfection screening for genes related to cancer
            development and progression
  JOURNAL   Proc Natl Acad Sci U S A 101 (44), 15724-15729 (2004)
   PUBMED   15498874
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 Dec 14:101(50):17565]
REFERENCE   7  (bases 1 to 2923)
  AUTHORS   Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
            Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
            Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
            Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
            Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
            Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
            Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
            Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
            Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
            French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
            Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
            Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
            Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
            Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
            Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
            McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
            Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
            Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
            Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
            Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
            Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
            Bentley,D.R., Rogers,J. and Ross,M.T.
  TITLE     The DNA sequence and analysis of human chromosome 13
  JOURNAL   Nature 428 (6982), 522-528 (2004)
   PUBMED   15057823
REFERENCE   8  (bases 1 to 2923)
  AUTHORS   Gomes,I., Sharma,T.T., Edassery,S., Fulton,N., Mar,B.G. and
            Westbrook,C.A.
  TITLE     Novel transcription factors in human CD34 antigen-positive
            hematopoietic cells
  JOURNAL   Blood 100 (1), 107-119 (2002)
   PUBMED   12070015
  REMARK    GeneRIF: Novel transcription factors identified in human CD34
            antigen-positive hematopoietic stem cells.
REFERENCE   9  (bases 1 to 2923)
  AUTHORS   Martinez,E., Palhan,V.B., Tjernberg,A., Lymar,E.S., Gamper,A.M.,
            Kundu,T.K., Chait,B.T. and Roeder,R.G.
  TITLE     Human STAGA complex is a chromatin-acetylating transcription
            coactivator that interacts with pre-mRNA splicing and DNA
            damage-binding factors in vivo
  JOURNAL   Mol Cell Biol 21 (20), 6782-6795 (2001)
   PUBMED   11564863
REFERENCE   10 (bases 1 to 2923)
  AUTHORS   Schmidt,U., Fiedler,U., Pilarsky,C.P., Ehlers,W., Fussel,S.,
            Haase,M., Faller,G., Sauter,G. and Wirth,M.P.
  TITLE     Identification of a novel gene on chromosome 13 between BRCA-2 and
            RB-1
  JOURNAL   Prostate 47 (2), 91-101 (2001)
   PUBMED   11340631
  REMARK    GeneRIF: mRNA is down-regulated in human prostate cancer, also
            described as C13
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL391383.15 and AL138706.9.
            
            On Nov 22, 2018 this sequence version replaced NM_001014286.2.
            
            Transcript Variant: This variant (1) differs in the 5' UTR, has an
            alternate splice site in the 5' coding region and an additional
            exon in the 3' coding region which results in a frameshift,
            compared to variant 2. The resulting isoform (a) is longer; it
            lacks an internal aa in the N-terminal region, but has a longer and
            distinct C-terminus, compared to isoform b.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030686.2, SRR18074969.3685803.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000350612.11/ ENSP00000218894.10
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-130               AL391383.15        23571-23700         c
            131-226             AL391383.15        15500-15595         c
            227-262             AL391383.15        12576-12611         c
            263-321             AL391383.15        11890-11948         c
            322-388             AL391383.15        11547-11613         c
            389-515             AL391383.15        9259-9385           c
            516-619             AL391383.15        8090-8193           c
            620-736             AL391383.15        4588-4704           c
            737-790             AL391383.15        4417-4470           c
            791-930             AL138706.9         190493-190632       c
            931-1087            AL138706.9         188783-188939       c
            1088-1144           AL138706.9         188611-188667       c
            1145-1216           AL138706.9         186809-186880       c
            1217-1374           AL138706.9         185192-185349       c
            1375-1401           AL138706.9         183834-183860       c
            1402-1434           AL138706.9         183248-183280       c
            1435-1552           AL138706.9         182364-182481       c
            1553-1655           AL138706.9         181384-181486       c
            1656-1814           AL138706.9         181079-181237       c
            1815-1884           AL138706.9         179055-179124       c
            1885-2039           AL138706.9         178492-178646       c
            2040-2095           AL138706.9         176386-176441       c
            2096-2215           AL138706.9         174289-174408       c
            2216-2321           AL138706.9         169236-169341       c
            2322-2425           AL138706.9         167596-167699       c
            2426-2923           AL138706.9         166356-166853       c
FEATURES             Location/Qualifiers
     source          1..2923
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q13.3"
     gene            1..2923
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="SPT20 homolog, SAGA complex component"
                     /db_xref="GeneID:55578"
                     /db_xref="HGNC:HGNC:20596"
                     /db_xref="MIM:613417"
     exon            1..130
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            131..226
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     CDS             224..2563
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="isoform a is encoded by transcript variant 1;
                     transcription factor (p38 interacting protein); suppressor
                     of Ty 20 homolog; tumor rejection antigen; protein FAM48A;
                     family with sequence similarity 48, member A;
                     transcription factor SPT20 homolog"
                     /codon_start=1
                     /product="transcription factor SPT20 homolog isoform a"
                     /protein_id="NP_001014308.2"
                     /db_xref="CCDS:CCDS31959.1"
                     /db_xref="GeneID:55578"
                     /db_xref="HGNC:HGNC:20596"
                     /db_xref="MIM:613417"
                     /translation="MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLY
                     IEECEKEPEVKKLRRNVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETI
                     RLPYEEGELLEYLDAEELPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQ
                     SRHILLRPTMQTLICDVHSITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCT
                     ANRLLYNKQKMNTRPMKRCFKRYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAG
                     QHYDLKISKAGNCVDMWKRSPCNLAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVK
                     DDYVFECEAGTQYQKTKLTILQSLGDPLYYGKIQPCKADEESDSQMSPSHSSTDDHSN
                     WFIIGSKTDAERVVNQYQELVQNEAKCPVKMSHSSSGSASLSQVSPGKETDQTETVSV
                     QSSVLGKGVKHRPPPIKLPSSSGNSSSGNYFTPQQTSSFLKSPTPPPSSKPSSIPRKS
                     SVDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPM
                     LGCNTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQ
                     LPGGSLIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQA
                     AVINLTGVGSFMQSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQQIQQLRFLQ
                     HQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTPKF"
     exon            227..262
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            263..321
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            322..388
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            389..515
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            516..619
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            620..736
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            737..790
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            791..930
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1087
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1144
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1216
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1374
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1401
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1434
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1552
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1655
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..1814
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1815..1884
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..2039
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2095
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2215
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2216..2321
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..2425
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..2923
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2714..2719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="hexamer: AATAAA"
     polyA_site      2741
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="major polyA site"
     regulatory      2894..2899
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="hexamer: AATACA"
     polyA_site      2923
                     /gene="SUPT20H"
                     /gene_synonym="C13; C13orf19; FAM48A; FP757; P38IP; SPT20"
                     /note="major polyA site"
ORIGIN      
        1 aatcggaagt gcggccgccg gaactggctg ttggtggggg tgcagcactg agccgccgac
       61 ggggcgggtg ggctttgctg ccgagcaggc ggcgccgtct tggggcctag cggcgaggcg
      121 acccgcacag tactgtaaga ttgatgttaa aggcatggtg ttcaccccac ttcatcagcg
      181 tacataagtt atctcttctt ttggaccctt attttatgcc ataatgcaac aagctttaga
      241 actagctttg gatcgtgcag agtatgtcat tgaaagtgcc cgacagagac ctcctaaaag
      301 gaaataccta tcaagtggaa gaaaatctgt atttcaaaaa ctttatgact tgtatattga
      361 agaatgtgaa aaagaacctg aagttaagaa attaagaaga aatgtgaact tgttagagaa
      421 gcttgttatg caagagactt tgtcatgttt agtggtcaat ctatacccag gaaatgaggg
      481 atattctctg atgctcaggg gaaaaaacgg atcagattcc gagaccattc gactgcccta
      541 tgaagaagga gagttgcttg aatatttgga tgcagaagaa ttacctccta ttttggttga
      601 tctcctagaa aaatctcagg ttaatatttt tcattgcgga tgtgtcatag cagaaatacg
      661 tgactacagg cagtccagta acatgaaatc tcctggttac caaagtcggc acattctctt
      721 acgtccaaca atgcagactt taatttgtga tgtacattca ataacaagtg ataaccacaa
      781 atggacccag gaagacaaac ttttgcttga gagccagctc atcctagcta cagctgaacc
      841 actctgtctt gatccttcta tagcagtcac ctgcactgca aacagactgc tctataacaa
      901 gcaaaagatg aacactcgcc caatgaaacg gtgtttcaag aggtattcca gatcctctct
      961 gaatcggcag caagatctat ctcattgtcc acctcctcct cagctgaggt tacttgattt
     1021 cttacaaaaa agaaaggaaa gaaaagcagg tcagcattat gacctcaaaa tttctaaggc
     1081 aggaaattgt gtagatatgt ggaaacggag tccctgtaat ttggccatac cttctgaagt
     1141 agatgtggag aaatatgcta aagtggaaaa gtctatcaaa tctgatgact cacagccaac
     1201 agtctggcca gcccatgatg taaaagatga ttatgtattt gaatgtgaag ctggtactca
     1261 gtatcagaaa acaaagctga ccatcttgca gtcgcttgga gatccacttt actatggtaa
     1321 aatacagcca tgtaaagcag atgaagaaag tgacagccag atgtctccat cacactcgtc
     1381 cacagatgat cattcaaatt ggttcattat tggatcaaag accgatgctg agagggtagt
     1441 caatcagtac caagaattag tccagaatga agccaaatgt ccggtcaaga tgtcacacag
     1501 ctccagtggc tcagccagtc tgagtcaggt ttctccaggg aaagaaacag atcaaactga
     1561 aaccgtgtca gttcagtctt cggtattggg gaagggtgta aaacatcgac ccccaccaat
     1621 caaacttccc tcaagctcag gaaatagttc ctcaggtaac tattttacac cacaacagac
     1681 aagcagcttt ctcaaatctc caactcctcc tccttcttct aagccatcaa gtattcctcg
     1741 gaaatcatct gtggatctca atcaagttag catgctttct ccagctgccc tatcacctgc
     1801 cagctcatca caaagaacca cggccaccca ggtcatggca aactctgctg gacttaactt
     1861 catcaatgta gtgggctctg tttgtggggc ccaggctttg atgagtggtt caaaccccat
     1921 gctgggctgt aacactggtg ccataactcc tgcaggaata aacctgagcg gccttctacc
     1981 ctcaggaggt ctgctaccaa atgcactgcc cagtgcaatg caggcagctt ctcaagcagg
     2041 tgttccattt ggtttaaaaa atacttcaag tctcaggccc ttaaatctac tccagcttcc
     2101 aggtggttca cttattttta acactctgca gcagcagcaa cagcagctct cccagtttac
     2161 accacaacaa cctcagcagc ccacaacttg tagtcctcaa cagccagggg agcagggttc
     2221 tgagcaaggt tcaaccagtc aagaacaggc cttatctgct cagcaagctg ctgttattaa
     2281 ccttactgga gtaggaagtt ttatgcagtc acaggcagct gtgttgtctc agcttggctc
     2341 tgccgagaac agacctgagc aaagccttcc tcagcagaga ttccagctct cctctgcctt
     2401 tcaacagcag cagcaacaga tacaacagtt gcgattcttg cagcatcaaa tggctatggc
     2461 agcagcagca gcacaaacag ctcagctaca tcatcatcgg catacaggca gccagtcaaa
     2521 aagtaaaatg aagagaggca cgccaaccac tccaaaattt tgagtcttgc attacttttt
     2581 gttccttttt taaaaacaca agagcactga atcaaaagaa ttgagtttct actttttgtt
     2641 ttttttaatg tgtcagtatt ttacattgct agatgtacaa actttataca gaagcacaac
     2701 cttatcattt ttaaataaaa acagggaaat ggtttaacaa actagggttg gtttgcctaa
     2761 gtcattgctt tttaaaaatg gtttcactat acataatata tatggaagtg acctaagaaa
     2821 taatagaaac atctttcaga agaatgtagt ttgatattta tttagtataa aacgtttgtg
     2881 cacagtgtta acaaatacaa tttttacaaa tctgttttga aaa
//
