LOCUS       NM_001163561             821 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens sperm-tail PG-rich repeat containing 4 (STPG4),
            transcript variant 1, mRNA.
ACCESSION   NM_001163561
VERSION     NM_001163561.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 821)
  AUTHORS   Barber,M.J., Mangravite,L.M., Hyde,C.L., Chasman,D.I., Smith,J.D.,
            McCarty,C.A., Li,X., Wilke,R.A., Rieder,M.J., Williams,P.T.,
            Ridker,P.M., Chatterjee,A., Rotter,J.I., Nickerson,D.A.,
            Stephens,M. and Krauss,R.M.
  TITLE     Genome-wide association of lipid-lowering response to statins in
            combined study populations
  JOURNAL   PLoS One 5 (3), e9763 (2010)
   PUBMED   20339536
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073283.8.
            
            On Nov 22, 2018 this sequence version replaced NM_001163561.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.67119.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000445927.7/ ENSP00000408527.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AC073283.8         98848-98985         c
            139-198             AC073283.8         96634-96693         c
            199-456             AC073283.8         94935-95192         c
            457-521             AC073283.8         73873-73937         c
            522-576             AC073283.8         73618-73672         c
            577-681             AC073283.8         33947-34051         c
            682-821             AC073283.8         30668-30807         c
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p21"
     gene            1..821
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /note="sperm-tail PG-rich repeat containing 4"
                     /db_xref="GeneID:285051"
                     /db_xref="HGNC:HGNC:26850"
     exon            1..138
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..804
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C2orf61; gonad-specific expression
                     gene protein; sperm-tail PG-rich repeat-containing protein
                     4; protein STPG4"
                     /codon_start=1
                     /product="protein STPG4 isoform 1"
                     /protein_id="NP_001157033.1"
                     /db_xref="CCDS:CCDS54356.1"
                     /db_xref="GeneID:285051"
                     /db_xref="HGNC:HGNC:26850"
                     /translation="MDQPAVATASTSIREDLVGGESFITASKPAQKTSSFEREGWWRI
                     ALTDTPIPGTYHLKTFIEESLLNPVIATYNFKNEGRKKPPLVQRNNPVLNDLPQYMPP
                     DFLDLLKKQVATYSFKDKPRPSPSTLVDKDQSLQLSPGQYNVLPAPVPKYASRSCVFR
                     STVQRFPTTYFIPHEGPGPGHYNVKMPPTSSVTSCFQSRVPRFLPSCSKTPGPGAYTT
                     LRQFPKQSPTIAKMGQEHSLFFNNNNWLLK"
     exon            139..198
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     exon            199..456
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     exon            457..521
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     exon            522..576
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     exon            577..681
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     exon            682..821
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      800..805
                     /regulatory_class="polyA_signal_sequence"
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /note="hexamer: AATAAA"
     polyA_site      821
                     /gene="STPG4"
                     /gene_synonym="C2orf61; GSE"
                     /note="major polyA site"
ORIGIN      
        1 acacccgcct cctagcaacc ggagctcagg ttcagcctag agagagagga ggccaccatg
       61 gaccagccag ccgtcgccac cgcttccacc tcaataaggg aagacctggt gggtggagaa
      121 tcattcatca cagcttcgaa accagcccaa aagacttcct cttttgaaag agaaggatgg
      181 tggagaatag cattaacaga tactcctata cctggcactt accacttgaa aacttttatt
      241 gaagaatccc tattaaatcc agtgatagca acctacaatt ttaaaaacga aggaaggaaa
      301 aagccacctc ttgtgcaaag aaacaatcca gtcctaaatg atcttccgca gtatatgcct
      361 cctgacttcc tggacctgtt aaagaagcaa gtggctactt actcattcaa agacaaacca
      421 cggccaagcc ccagcacact agttgacaaa gatcagtcac ttcagctttc tccggggcaa
      481 tacaacgtgc ttcctgcacc agttcccaaa tatgcttcca ggagctgtgt atttcgctca
      541 acagttcaaa gattcccaac aacctatttt attccccatg aaggccctgg tccaggtcat
      601 tataatgtga aaatgcctcc aacaagctct gtcacttctt gttttcaatc cagagtccct
      661 cgattcttgc ccagctgttc aaaaacccca ggcccaggag catatacaac tttaagacaa
      721 ttccctaagc agtctccgac catagccaaa atgggccaag agcatagcct tttcttcaac
      781 aacaacaatt ggcttttaaa ataaagtgat cttggcacca a
//
