LOCUS       NM_174952               1892 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens sperm tail PG-rich repeat containing 2 (STPG2), mRNA.
ACCESSION   NM_174952
VERSION     NM_174952.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Jiang,J., Fridley,B.L., Feng,Q., Abo,R.P., Brisbin,A., Batzler,A.,
            Jenkins,G., Long,P.A. and Wang,L.
  TITLE     Genome-wide association study for biomarker identification of
            Rapamycin and Everolimus using a lymphoblastoid cell line system
  JOURNAL   Front Genet 4, 166 (2013)
   PUBMED   24009623
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  AUTHORS   Yakut,S., Cetin,Z., Clark,O.A., Usta,M.F., Berker,S. and Luleci,G.
  TITLE     Exceptional complex chromosomal rearrangement and microdeletions at
            the 4q22.3q23 and 14q31.1q31.3 regions in a patient with
            azoospermia
  JOURNAL   Gene 512 (1), 157-160 (2013)
   PUBMED   23031811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC019077.9, BC036870.1 and AC034154.6.
            
            On Nov 22, 2018 this sequence version replaced NM_174952.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036870.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000295268.4/ ENSP00000295268.3
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-236               AC019077.9         32502-32737         c
            237-1881            BC036870.1         1-1645
            1882-1892           AC034154.6         134397-134407
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q22.3-q23"
     gene            1..1892
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /note="sperm tail PG-rich repeat containing 2"
                     /db_xref="GeneID:285555"
                     /db_xref="HGNC:HGNC:28712"
     exon            1..435
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     CDS             327..1706
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /codon_start=1
                     /product="sperm-tail PG-rich repeat-containing protein 2"
                     /protein_id="NP_777612.1"
                     /db_xref="CCDS:CCDS3645.1"
                     /db_xref="GeneID:285555"
                     /db_xref="HGNC:HGNC:28712"
                     /translation="MYDRAPRLLKLAEGGSTEAHVGPGSYQVPFLKQQATGSNAPFLS
                     LTARESTFTIASSIEKAVPGPGHYNVSEAQKISRSPTLTRSVDVPSIPSCGKSYGYHI
                     NDDGSIIKCFPPACDSTLGPAYYKPQFDVSNATLKYKGIHFGNSSGRQELPKKSGPGP
                     GQYDIVQKKTSYYENVNIKRDQQQNYCSFIPRLYEIIVLQEKKKRFLPMKSITPAPGT
                     YNEPRTALKSLKKTSGLKNIPFGQSAVRFTQDIRTEEMPGPGFYNVLNNTIIASVRNI
                     CSKKQKKSAFGSSVPRTFFSVQKEACATPGPADYQEFWHSQGVGISDELPNLTNKYAA
                     FLSRAKRTMKVPDMVIPAPGSYDVHKSYEMSQVKHKYMPPRSLVAKRKHASFLSATPR
                     CLEKVTDGPGPAAYNPVLRKSCPIPLFVKASKRFEESKEITPGPATYEISQEKKKGNL
                     IGEMAADIM"
     exon            436..548
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            549..713
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            714..826
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            827..938
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1098
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1259
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1370
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1530
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1646
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1892
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1871..1876
                     /regulatory_class="polyA_signal_sequence"
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /note="hexamer: AATAAA"
     polyA_site      1892
                     /gene="STPG2"
                     /gene_synonym="C4orf37"
                     /note="major polyA site"
ORIGIN      
        1 agggccggaa gcaccggggc gagcgtctaa tccctaatac ccaattttgg tggcgtgcac
       61 ctggcaaact gatgattgtg tgggacgtct aatctctagt cgctcacccc tctactttac
      121 cacagagcta gaaatcgatt tgaggaaatc tggtatcaat gagcgggcgg ggagacaacc
      181 ccacccctaa tttccctgtt tacggaagtt ctttcccggc ctcctcagac tggtgtcggc
      241 ttcctttttc tccacacttc tagctacctt gtttttatcg ttttcggcac ctgcccttcc
      301 ccagcgcccc caccaccccg agcactatgt atgatcgggc tccccgcctg ctcaaattgg
      361 ctgaaggtgg cagcactgag gcccatgtgg gtcctggatc ctaccaggta cctttcctga
      421 agcagcaggc gacaggtagt aatgcaccat ttctttcttt gactgccaga gaaagtactt
      481 ttaccattgc ctctagcatt gagaaagctg ttccaggtcc aggacactat aatgtttcag
      541 aagcacagaa aatttcaaga tcacctacac ttaccagaag tgttgatgtt ccttcaattc
      601 cttcttgtgg aaagtcatat ggttatcata ttaatgatga tggcagtatt ataaaatgtt
      661 ttccacctgc ttgtgacagt acacttggtc cagcatacta caaacctcaa tttgatgttt
      721 ccaatgcaac tttgaaatac aaaggtatac attttggcaa ctcttcagga agacaagagt
      781 tacctaaaaa gtcaggtcct ggtccaggac agtatgatat agtccagaaa aagacatcat
      841 attatgaaaa tgttaacatc aagagagatc aacaacaaaa ttattgttca tttatcccac
      901 gactatatga aataatagta ttgcaggaga aaaaaaagag atttttacct atgaaatcaa
      961 tcaccccggc tcctggcaca tataatgaac ctcgaactgc tctcaagtct ttgaagaaaa
     1021 catcaggact gaaaaatatt ccatttggtc aaagtgctgt tcgattcaca caggacatca
     1081 ggacagagga aatgccaggt cctggatttt ataatgtctt gaacaatact ataattgcca
     1141 gtgttagaaa tatctgctca aagaaacaga agaaaagtgc atttggttct tctgttcctc
     1201 ggactttctt ctcggttcag aaagaagctt gtgctacccc tggacctgct gattatcagg
     1261 aattttggca ttcacagggt gtgggaattt ctgatgaatt acctaacttg actaacaaat
     1321 atgctgcttt cttgtcaaga gccaaaagaa ctatgaaagt accagatatg gttattccag
     1381 cgccaggcag ctatgatgtt cacaaatcat atgagatgtc ccaagttaag cataaatata
     1441 tgccacctcg tagtttagtg gctaaaagaa aacatgcctc ttttcttagt gcaactcctc
     1501 ggtgcctaga aaaagtgact gatgggccag gtcctgcagc atacaatcct gttttaagga
     1561 aatcttgccc cataccctta tttgtgaaag catcaaagcg ctttgaagag tccaaagaga
     1621 ttactccagg cccagcaaca tatgagatat cccaggagaa aaagaaagga aatctcattg
     1681 gtgaaatggc tgctgatata atgtgacata aatttatggc aaaaacttaa aaaacaactt
     1741 catggaagtc agtttatttc tttgtcattt taacaaaatt tattccaaat ataggagtaa
     1801 taaaagcata attttcactt gttcaggcat tcgctcaggc tttagtgact atatgacaca
     1861 accacggaga aataaacctt gttaagacaa aa
//
