LOCUS       XM_047428314            5383 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens STIL centriolar assembly protein (STIL),
            transcript variant X8, mRNA.
ACCESSION   XM_047428314
VERSION     XM_047428314.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5383
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5383
                     /gene="STIL"
                     /gene_synonym="MCPH7; SIL"
                     /note="STIL centriolar assembly protein; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 21 ESTs, 520 long SRA reads, 4 Proteins, and
                     94% coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6491"
                     /db_xref="HGNC:HGNC:10879"
                     /db_xref="MIM:181590"
     CDS             523..4386
                     /gene="STIL"
                     /gene_synonym="MCPH7; SIL"
                     /codon_start=1
                     /product="SCL-interrupting locus protein isoform X2"
                     /protein_id="XP_047284270.1"
                     /db_xref="GeneID:6491"
                     /db_xref="HGNC:HGNC:10879"
                     /db_xref="MIM:181590"
                     /translation="MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIY
                     LHLSYYRNPKLVVTEKTIRLAYRHAKQNKKNSSCFLLGSLTADEDEEGVTLTVDRFDP
                     GREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSK
                     DSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNL
                     SSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVW
                     ACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSK
                     ETLHLFKNVEPPDKNPIRCELSAESQNAETEFFSKASKNFSIKRSSQKLSSGKMPIHD
                     HDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNN
                     ENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQP
                     PAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLA
                     PQSQPHDFVFSPHNSGRPMELQIPTPPLPSYCSTNVCRCCQHHSHIQYSPLNSWQGAN
                     TVGSIQDVQSEALQKHSLFHPSGCPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEP
                     SPVARPPSHMDLCNPQPCTVCMHTPKTESDNGMMGLSPDAYRFLTEQDRQLRLLQAQI
                     QRLLEAQSLMPCSPKTTAVEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASL
                     FWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEES
                     NIAVEEEFNQPLSVSNSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSET
                     SEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTR
                     TQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDSPTKVKKNAHNVDHASVLAC
                     ISPEAVISGLNCMSFANVGMSGLSPNGVDLSMEANAIALKYLNENQLSQLSVTRSNQN
                     NCDPFSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDEEEPPDNAD
                     SKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQ
                     TKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETL
                     KQMNSMNSVGTFLDVKRLRQLPKLF"
ORIGIN      
        1 agttcccgcg accccaacgt cccagaggcg gggccggagt cggcggtggc gctccttgga
       61 gccggctccc gctcctaccc tgcaaacaga cctcagctcc gcggaagttg cgtttcactc
      121 tttggcccag gctggagtga agtggagtga tctcggctca ctgcaacctc cgtcccccgg
      181 gttcaagcga ttctcctgcc tcagcctccc tagtagctgg gattacaggc aaacgccacc
      241 acgctcggct gatttttgta tttttagtag agacggggtt tcaccatgtt ggtcgggctg
      301 gtctggaaat cctgacttca ggtgatccac ccgcctcggc ctcccaaaat gctgggatta
      361 caagcgtgag ccaccgcccc tgacatgagc cattgacttt taaagcagga gaataatttg
      421 atcagattta tatggaaaca ctcttctagc agcattatgg ggacttttcc ataagtctgg
      481 atactgagga tttggaatta aagaaatcat tcaccagaca tcatggagcc tatatatcct
      541 tttgcacggc cccagatgaa taccaggttt ccttcaagca ggatggtacc tttccacttt
      601 cctccatcaa aatgtgcact ttggaaccca acgccaactg gagatttcat ctacttacat
      661 ctcagttact acagaaatcc aaagcttgtg gtgactgaga agaccatccg acttgcttat
      721 cgtcatgcta agcagaataa aaaaaattcg tcatgctttt tacttggttc tctgacagca
      781 gacgaagatg aagaaggtgt aacattgaca gtagatcgct ttgatcctgg tcgagaagta
      841 cctgaatgcc tagaaataac ccctactgct tctcttcctg gggacttttt gattccatgc
      901 aaagttcata ctcaagaact ttgttcaaga gaaatgatag ttcacagtgt agatgacttc
      961 agttcagctt taaaggctct acagtgccat atatgtagca aagattcctt ggactgtggt
     1021 aagctgcttt ccctaagagt tcatatcact tccagggaga gtttggacag tgtggaattt
     1081 gacttgcatt gggcagcagt aactctagca aataacttta aatgcacacc tgtgaagccc
     1141 atccccatta ttccaacagc tctggcaaga aacttgagca gtaatctgaa tatttctcaa
     1201 gttcaaggga cttataaata tggatatctt accatggatg aaacacgcaa attgttactt
     1261 ttgttggaat ctgatcccaa ggtttattct ctaccattgg tgggaatttg gctgtctgga
     1321 attacacata tctatagtcc tcaggtatgg gcttgctgtt tgcgatacat attcaattct
     1381 tctgttcaag aaagggtttt ttcagaatct ggaaatttca tcatagttct ctattctatg
     1441 acacataagg aacctgagtt ttatgaatgc ttcccttgtg atggcaagat acctgacttt
     1501 cggtttcagt tgctaaccag taaggaaaca ttacatcttt tcaaaaatgt tgaacctcct
     1561 gacaaaaatc caatccgttg tgaactgagc gctgaaagcc aaaatgcaga aacagagttt
     1621 ttcagtaagg cttccaagaa tttttcaatt aagaggtctt cccaaaagtt atcttctggg
     1681 aagatgccaa tacatgatca cgactctggt gttgaagatg aagatttttc tccaagacca
     1741 attcctagtc ctcatccagt gagtcagaag atttctaaga tccaaccatc agttcctgaa
     1801 ctttcacttg tgttggatgg caatttcata gaatcaaacc ctctgcctac tccattggaa
     1861 atggtgaata atgaaaatcc tcctttgatt aaccacttgg aacacttgaa gccattgcaa
     1921 ccccagcttt atgatgagaa acacagtcca gaagttgaag ctggagagcc ttccttgaga
     1981 ggaataccaa atcagttaaa ccaggataaa ccagctcttt tgagacactg caaagtaaga
     2041 cagccacctg cctataagaa agggaacccc cataccagga acagtattaa accatcttct
     2101 cataatgggc catctcatga tatatttgaa aagctccaaa cagtttctgc tggaaatgta
     2161 caaaacgaag agtatcctat aagaccctcc acacttaatt ctaggcagtc ttctcttgcc
     2221 ccgcagtccc aaccacacga ttttgttttt tcaccccata attcaggaag accaatggaa
     2281 cttcagatac ctactccccc actgccatct tactgttcca caaacgtttg caggtgttgt
     2341 cagcatcata gtcatattca atatagtccg ctaaattctt ggcaaggagc aaacacagtt
     2401 ggatccattc aagatgtcca gtctgaagcc cttcaaaagc attcattatt tcacccaagt
     2461 ggatgtccag ccctgtactg taatgcattc tgttcttcaa gtagtcctat agccttgaga
     2521 cctcagggag atatgggcag ttgttctccc cacagcaata ttgaaccatc gcctgtggca
     2581 agaccgcctt cacatatgga cttatgtaac ccacagcctt gcacagtgtg catgcacaca
     2641 cccaagactg agtcagataa tggaatgatg ggactatctc cagatgcata tcggttcctc
     2701 acagaacaag acagacagct aagactactt caggcacaga ttcagcgttt gttggaagca
     2761 cagtctctga tgccctgttc ccctaagaca actgctgttg aagacacagt gcaagctgga
     2821 agacaaatgg agttggtttc tgtggaagca cagtcttccc ctggcttgca catgagaaaa
     2881 ggtgtaagca ttgctgtgag cacaggtgct agcttgtttt ggaatgcagc aggtgaggat
     2941 caagagcctg actctcaaat gaagcaagat gataccaaaa tttccagtga ggacatgaat
     3001 ttttctgtcg atattaataa tgaagtcaca agtcttccag gtagtgcatc ttcattaaaa
     3061 gcagttgata ttcccagttt tgaagagagc aacattgctg tggaagaaga atttaaccag
     3121 ccactttctg tatccaactc ttctctagtt gtgagaaaag aacctgatgt acctgtgttc
     3181 tttccaagtg gccagctggc agaaagtgta agcatgtgtt tacagactgg accaacaggg
     3241 ggtgccagta acaattctga aacatcagag gaaccaaaaa ttgagcatgt aatgcaaccc
     3301 ttgcttcatc aaccatcaga taaccagaaa atttaccagg atttattggg tcaagtaaac
     3361 cacctattaa atagttcctc caaggaaact gagcagccgt ctaccaaagc agtaattatc
     3421 agtcatgaat gcaccagaac ccaaaacgtt taccatacaa agaaaaaaac acatcattca
     3481 agactggtgg acaaagattg tgtccttaat gcaactctta agcaactaag aagccttgga
     3541 gtaaaaattg attctcccac taaagtgaag aaaaatgcac ataacgtgga tcacgccagt
     3601 gtgttggcat gcatcagccc agaagcagtg atctctggat taaactgcat gtcatttgct
     3661 aatgttggca tgagcggctt aagccccaat ggtgtggatt tgagcatgga ggcaaatgct
     3721 atagctctga aatatttaaa tgaaaatcag ctgtcacaac tgtctgtcac tcgatcgaac
     3781 caaaataatt gtgacccatt cagccttctc catattaata cagacagaag cacagtgggg
     3841 cttagtttaa tttcaccaaa caacatgtca tttgcaacca aaaaatatat gaagagatat
     3901 ggactcctac aaagcagtga caatagtgaa gatgaagagg aacctcccga caatgcagat
     3961 agcaagagtg aatatttatt gaatcagaac cttaggtcca tacctgaaca gcttggtggt
     4021 cagaaagagc cttctaagaa tgaccatgaa ataattaatt gttctaactg tgaatctgtg
     4081 gggaccaacg cagatacgcc agtattgaga aatattacaa atgaagtttt gcagacaaaa
     4141 gcaaaacagc agttgactga aaagccagct ttcttagtaa agaaccttaa accaagtcct
     4201 gcagtgaacc ttcgaaccgg gaaagcagag ttcactcaac atcctgagaa agaaaatgaa
     4261 ggggacatta caatttttcc tgaaagtttg caaccttctg aaacgctaaa gcagatgaat
     4321 agcatgaatt cagtaggcac cttcttagat gtaaaacgtc tcagacagtt accaaaatta
     4381 ttttaacctt ttaactccct gcccttttaa tacagggaca gggtgtctcc tgaagatact
     4441 tagggaaaac aggagcctac cacaaggctc ctgatcattc tggagtcact gtttcttggt
     4501 agcagccaat tgggaagagt gacttctgtg agatggctgg ctggtgatag gactaagttc
     4561 tcattgttca aatagagctg ttcaacatca ctgaaacctt taagaaaagc cctgagatca
     4621 gttattccta caagtttaag tagtagacag atactatcca gctctaagtc tcaactgctc
     4681 ttttatactg tacttttttt tttgagacgg agttttgctc ttgtagccca ggctggagtg
     4741 caatggcagg atctcagatc actgcaacct ctgcctcctg ggttcaagcg attttcctgc
     4801 ttcatcttcc caggtagctg ggattacagg catgtgccac aacgcctggc taattttgta
     4861 tttttagtag agactggttt ctccatgttg gtcaggctgg tctcaaactc ccgacctcag
     4921 gtgatccgcc cgcctcggcc tcctaaagtg ctgggattac aggcgtgagc cactgcgccc
     4981 agctatactg tatattttaa gaagttccag catgttgcat ctctgcattt atcctatatc
     5041 attaaaagaa cataagttat catggtgttg ggtaaattag cgaaatcaac ccttcctaag
     5101 tttaagggaa aagttatttt taaaaacaac ttaataaaaa cttacactct tttatacaag
     5161 agtgtatttc cccttaatta ggatgcatgt tgattaaact cgagatacag ctttttgcag
     5221 tatggtgggt tggttttggt gtaacatctt caacatgtca cactggctat caaagaataa
     5281 gaaaattatt gagtatgagt gtgttttata aactttctga gtttttcaga tgtcttaata
     5341 ttttttaata gaacttaata aaatgtctag attgactatt ttc
//
