LOCUS       NM_017564               8243 bp    mRNA    linear   PRI 28-AUG-2024
DEFINITION  Homo sapiens stabilin 2 (STAB2), mRNA.
ACCESSION   NM_017564
VERSION     NM_017564.10
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8243)
  AUTHORS   Yu,W., Srivastava,R., Srivastava,S., Ma,Y., Shankar,S. and
            Srivastava,R.K.
  TITLE     Oncogenic Role of SATB2 In Vitro: Regulator of Pluripotency,
            Self-Renewal, and Epithelial-Mesenchymal Transition in Prostate
            Cancer
  JOURNAL   Cells 13 (11), 962 (2024)
   PUBMED   38891096
  REMARK    GeneRIF: Oncogenic Role of SATB2 In Vitro: Regulator of
            Pluripotency, Self-Renewal, and Epithelial-Mesenchymal Transition
            in Prostate Cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8243)
  AUTHORS   Jo,H.S. and Kim,H.J.
  TITLE     Stabilin-2 mediated apoptotic cell phagocytosis induces
            interleukin-10 expression by p38 and Pbx1 signaling
  JOURNAL   Cell Biochem Biophys 82 (2), 919-925 (2024)
   PUBMED   38480573
  REMARK    GeneRIF: Stabilin-2 mediated apoptotic cell phagocytosis induces
            interleukin-10 expression by p38 and Pbx1 signaling.
REFERENCE   3  (bases 1 to 8243)
  AUTHORS   Li,J., Zeng,Q., Lin,J., Huang,H. and Chen,L.
  TITLE     Loss of SATB2 and CDX2 expression is associated with DNA mismatch
            repair protein deficiency and BRAF mutation in colorectal cancer
  JOURNAL   Med Mol Morphol 57 (1), 1-10 (2024)
   PUBMED   37583001
  REMARK    GeneRIF: Loss of SATB2 and CDX2 expression is associated with DNA
            mismatch repair protein deficiency and BRAF mutation in colorectal
            cancer.
REFERENCE   4  (bases 1 to 8243)
  AUTHORS   Holte,C., Szafranska,K., Kruse,L., Simon-Santamaria,J., Li,R.,
            Svistounov,D. and McCourt,P.
  TITLE     Highly oxidized albumin is cleared by liver sinusoidal endothelial
            cells via the receptors stabilin-1 and -2
  JOURNAL   Sci Rep 13 (1), 19121 (2023)
   PUBMED   37926735
  REMARK    GeneRIF: Highly oxidized albumin is cleared by liver sinusoidal
            endothelial cells via the receptors stabilin-1 and -2.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8243)
  AUTHORS   Xin,T., Li,Q., Bai,R., Zhang,T., Zhou,Y., Zhang,Y., Han,B. and
            Yang,R.
  TITLE     A novel mutation of SATB2 inhibits odontogenesis of human dental
            pulp stem cells through Wnt/beta-catenin signaling pathway
  JOURNAL   Stem Cell Res Ther 12 (1), 595 (2021)
   PUBMED   34863303
  REMARK    GeneRIF: A novel mutation of SATB2 inhibits odontogenesis of human
            dental pulp stem cells through Wnt/beta-catenin signaling pathway.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8243)
  AUTHORS   Smedsrod,B., Johansson,S. and Goerdt,S.
  TITLE     Shooting HARE
  JOURNAL   Glycobiology 13 (5), 11G-12G (2003)
   PUBMED   12751488
REFERENCE   7  (bases 1 to 8243)
  AUTHORS   Zhou,B., McGary,C.T., Weigel,J.A., Saxena,A. and Weigel,P.H.
  TITLE     Purification and molecular identification of the human hyaluronan
            receptor for endocytosis
  JOURNAL   Glycobiology 13 (5), 339-349 (2003)
   PUBMED   12626425
  REMARK    GeneRIF: amino acid sequence of 190-kDa protein composed of 1416
            amino acids and alignment with rat sequence
REFERENCE   8  (bases 1 to 8243)
  AUTHORS   Tamura,Y., Adachi,H., Osuga,J., Ohashi,K., Yahagi,N., Sekiya,M.,
            Okazaki,H., Tomita,S., Iizuka,Y., Shimano,H., Nagai,R., Kimura,S.,
            Tsujimoto,M. and Ishibashi,S.
  TITLE     FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation
            end products
  JOURNAL   J Biol Chem 278 (15), 12613-12617 (2003)
   PUBMED   12473645
REFERENCE   9  (bases 1 to 8243)
  AUTHORS   Adachi,H. and Tsujimoto,M.
  TITLE     FEEL-1, a novel scavenger receptor with in vitro bacteria-binding
            and angiogenesis-modulating activities
  JOURNAL   J Biol Chem 277 (37), 34264-34270 (2002)
   PUBMED   12077138
REFERENCE   10 (bases 1 to 8243)
  AUTHORS   Politz,O., Gratchev,A., McCourt,P.A., Schledzewski,K., Guillot,P.,
            Johansson,S., Svineng,G., Franke,P., Kannicht,C., Kzhyshkowska,J.,
            Longati,P., Velten,F.W., Johansson,S. and Goerdt,S.
  TITLE     Stabilin-1 and -2 constitute a novel family of fasciclin-like
            hyaluronan receptor homologues
  JOURNAL   Biochem J 362 (Pt 1), 155-164 (2002)
   PUBMED   11829752
  REMARK    GeneRIF: code for homologous transmembrane proteins featuring seven
            fasciclin-like adhesion domains, 18-20 epidermal-growth-factor
            domains, one X-link domain and three to six B-(X(7))-B
            hyaluronan-binding motifs
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC084364.20 and AY311388.1.
            
            On Nov 22, 2018 this sequence version replaced NM_017564.9.
            
            Summary: This gene encodes a large, transmembrane receptor protein
            which may function in angiogenesis, lymphocyte homing, cell
            adhesion, or receptor scavenging. The protein contains 7 fasciclin,
            15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like
            domains as well as a C-type lectin-like hyaluronan-binding Link
            module. The protein is primarily expressed on sinusoidal
            endothelial cells of liver, spleen, and lymph node. The receptor
            has been shown to bind and endocytose ligands such as hyaluronan,
            low density lipoprotein, Gram-positive and Gram-negative bacteria,
            and advanced glycosylation end products. Supporting its possible
            role as a scavenger receptor, the protein has been shown to cycle
            between the plasma membrane and lysosomes. [provided by RefSeq, Jul
            2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY311388.1, AJ295695.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145122, SAMEA2146236
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000388887.7/ ENSP00000373539.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AC084364.20        96400-96417
            19-8243             AY311388.1         19-8243
FEATURES             Location/Qualifiers
     source          1..8243
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q23.3"
     gene            1..8243
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /note="stabilin 2"
                     /db_xref="GeneID:55576"
                     /db_xref="HGNC:HGNC:18629"
                     /db_xref="MIM:608561"
     exon            1..285
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..7860
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /note="hyaluronic acid receptor for endocytosis; FAS1
                     EGF-like and X-link domain containing adhesion molecule-2;
                     fasciclin egf-like, laminin-type egf-like, and link
                     domain-containing scavenger receptor-2; CD44-like
                     precursor FELL; hepatic hyaluronan clearance receptor;
                     hyaluronan receptor for endocytosis"
                     /codon_start=1
                     /product="stabilin-2 precursor"
                     /protein_id="NP_060034.9"
                     /db_xref="CCDS:CCDS31888.1"
                     /db_xref="GeneID:55576"
                     /db_xref="HGNC:HGNC:18629"
                     /db_xref="MIM:608561"
                     /translation="MMLQHLVIFCLGLVVQNFCSPAETTGQARRCDRKSLLTIRTECR
                     SCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCP
                     GRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSC
                     SSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN
                     KLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCL
                     PVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHR
                     NANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQGRLTSFISLLD
                     KAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAGQMNIEYMNN
                     TDMFYTLTGKSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHILDRAMDKL
                     EPTFESNNEQTIMTMLQPRYSKFRSLLEETNLGHALDEDGVGGPYTIFVPNNEALNNM
                     KDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQLIQFNTTDNG
                     QILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRCDETKREMKLGTCVSCSL
                     VYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQC
                     PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGT
                     CNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKA
                     GYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNC
                     LLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQS
                     TSSGVWSCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQPTLSATSNLT
                     VLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSSDMLATSLQ
                     GNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNLLMRLEQ
                     MPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLRYHVV
                     LEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHGLG
                     KVLEIQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLF
                     IGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGF
                     SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC
                     NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPG
                     RRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKV
                     CTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPKTS
                     QYFFQLQEHFVKDLVGPGPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQ
                     LLLENLKLISNATSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSP
                     KNLLITPKDNSGRILQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTD
                     QALHALPAEQQDFLFNQDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSV
                     KCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASG
                     ECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRD
                     CQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSD
                     HGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYE
                     GDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLN
                     GGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL
                     HFQDTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGW
                     LETGRVAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMKDVNCTCKVGYVGD
                     GFSCSGNLLQVLMSFPSLTNFLTEVLAYSNSSARGRAFLEHLTDLSIRGTLFVPQNSG
                     LGENETLSGRDIEHHLANVSMFFYNDLVNGTTLQTRLGSKLLITASQDPLQPTETRFV
                     DGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAY
                     SYFRINRRTIGFQHFESEEDINVAALGKQQPENISNPLYESTTSAPPEPSYDPFTDSE
                     ERQLEGNDPLRTL"
     exon            286..419
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            420..535
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..621
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            622..691
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            692..787
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            788..913
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1110
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1244
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1378
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1461
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1611
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1755
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1756..1812
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1938
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..1992
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..2073
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2226
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2227..2289
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2376
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2463
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2464..2575
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2756
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2850
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            2851..3009
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3105
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3106..3201
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3249
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3250..3386
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3387..3501
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3502..3579
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3580..3678
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3679..3786
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3787..3918
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            3919..4047
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4048..4104
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4105..4200
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4201..4396
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4397..4492
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4493..4538
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4539..4615
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4616..4741
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4742..4815
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4816..4887
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            4888..5007
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5008..5055
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5056..5139
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5140..5286
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5287..5427
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5428..5487
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5488..5664
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5665..5754
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5755..5901
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5902..5958
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            5959..6085
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6086..6235
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6236..6340
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6341..6448
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6449..6642
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6643..6784
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6785..6918
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            6919..7084
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7085..7191
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7192..7311
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7312..7452
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7453..7563
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7564..7692
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7693..7809
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     exon            7810..8243
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8217..8222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /note="hexamer: AATAAA"
     polyA_site      8243
                     /gene="STAB2"
                     /gene_synonym="FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1"
                     /note="major polyA site"
ORIGIN      
        1 accaagactc ctggatttgc catttttcct ttctgaaggc aggtctcacc tatctcctgg
       61 ttcgatctag gaaaaaggaa aggaagggat ttaaaagtaa acagtgaaat gagaaagaat
      121 tcactgggag tttatcaaac taagttaaaa tagctaagtc agcctgacag gtgcttggca
      181 cagagaagga gcaaatattt cctcatgatg ctacaacatt tagtaatttt ttgtcttgga
      241 ttggttgtac aaaatttctg ctccccagct gaaaccacag ggcaggcaag aagatgtgat
      301 aggaagtctc ttcttacaat taggaccgag tgccgatcct gcgctctcaa ccttggagtc
      361 aagtgcccgg atggttacac catgattacc agtggctctg taggggttcg agattgcagg
      421 tacacctttg aggtcagaac atactctctg tctctccccg gatgccgcca tatttgtagg
      481 aaggactatc tccaacctcg gtgttgtcct ggccgctggg gcccagactg tatagagtgc
      541 ccaggtggag cggggtcacc ctgcaatggc agaggcagtt gtgctgaagg catggaagga
      601 aatggaacct gctcctgcca agaagggttt ggtggaacag cctgtgaaac ctgtgctgac
      661 gacaacttat ttggacccag ctgttcatca gtgtgcaact gtgtgcatgg ggtgtgcaac
      721 agtggactag atggcgatgg aacctgtgag tgctactctg cgtacactgg ccccaagtgt
      781 gacaagccca tccctgaatg tgcagccttg ctctgcccag aaaattccag atgttcgcct
      841 tccactgaag atgaaaacaa actggaatgc aaatgccttc ccaattaccg aggcgatggc
      901 aaatactgcg accccatcaa tccatgttta cgaaaaatct gccaccctca tgctcattgt
      961 acgtacctgg gaccaaatcg gcacagttgt acatgccaag aaggctaccg tggggatggc
     1021 caagtgtgct tgcctgtgga cccctgccaa attaactttg gaaactgccc tacaaagtct
     1081 acagtgtgca aatatgatgg gcctggacag tctcactgcg agtgtaagga gcattaccag
     1141 aatttcgtac ctggagtggg gtgcagtatg actgatatat gtaaatcaga taacccgtgt
     1201 cataggaatg caaattgcac caccgtcgca ccaggccgaa ctgaatgcat ttgccagaaa
     1261 ggttacgtgg gtgatggctt aacgtgttat ggaaacatta tggagcgact cagagaatta
     1321 aatactgaac ccagaggaaa atggcaagga aggctgacct ctttcatctc actcctagac
     1381 aaagcttatg cctggccact gagtaagctg ggacccttca cggtgctgtt acctacagac
     1441 aagggactga aaggattcaa tgtaaatgag cttttggtgg ataataaagc tgctcaatac
     1501 tttgtgaaac tccacataat tgctggtcag atgaacatcg aatatatgaa taacacagac
     1561 atgttctaca ccttgactgg aaagtcgggg gaaatcttca acagcgataa ggacaatcaa
     1621 ataaagctta aactccatgg aggcaaaaag aaggtaaaaa ttatacaagg ggacatcatt
     1681 gcttccaatg ggcttctgca catccttgac agagccatgg acaagttaga acccacattt
     1741 gagagcaaca atgagcaaac cataatgaca atgctacaac caaggtacag caagttcaga
     1801 tctttgttag aggaaaccaa tttgggacat gccttagatg aggatggagt tggtggacca
     1861 tacaccattt ttgttccaaa taatgaagca ttgaataaca tgaaggacgg cactctcgat
     1921 tacctccttt ctccagaggg atctcggaag cttctggaac tcgtcagata ccacattgtc
     1981 ccatttaccc agcttgaagt ggccactctc atctccaccc ctcacatcag gagcatggcc
     2041 aaccagctca tacagttcaa caccaccgac aatggacaga ttctggcaaa tgatgtggca
     2101 atggaagaaa ttgagatcac tgccaaaaat ggccgaattt acacactgac aggagttctc
     2161 attcctccct ccattgtccc gattctgccc catcgatgtg atgaaacaaa gagagagatg
     2221 aaactgggca cttgtgtgag ctgttctctg gtgtactgga gcagatgtcc tgctaactct
     2281 gagcccacag cactcttcac acacagatgt gtctacagtg gcaggtttgg gagcctgaag
     2341 agcggctgtg cccggtactg caatgccact gtgaagattc caaagtgctg caaaggcttc
     2401 tatggacctg actgcaacca gtgtccagga ggcttctcaa atccatgctc aggaaatgga
     2461 cagtgtgcag atagcctcgg cggcaacggg acatgcattt gtgaggaggg cttccaaggc
     2521 tcccagtgtc agttctgctc tgatcccaat aaatacggac ctcggtgtaa caaaaaatgc
     2581 ctgtgcgttc acggaacatg caataacagg atagacagcg atggggcctg cctcactggc
     2641 acatgcagag acggctctgc cgggagactc tgtgataagc agacctcagc ctgtgggccc
     2701 tacgtgcagt tctgtcacat ccacgccacc tgtgaataca gcaatgggac agccagttgt
     2761 atttgcaaag caggatatga aggagatgga actctgtgtt ctgagatgga cccttgcaca
     2821 ggactaactc caggaggctg tagccgcaat gcagaatgca tcaaaactgg cacgggcacc
     2881 cacacctgcg tgtgtcagca gggttggaca gggaatggga gagactgctc ggagatcaac
     2941 aactgcctgc tgcccagtgc aggcggctgc cacgacaacg catcctgttt gtatgtgggt
     3001 cccgggcaga atgagtgtga gtgcaagaaa ggatttcgag gaaatgggat tgactgtgaa
     3061 ccaataactt catgcttgga acaaaccggg aaatgtcatc cattggcaag ctgtcaatct
     3121 acttcgtctg gtgtctggag ctgtgtttgt caagagggct atgaaggaga tggctttctg
     3181 tgctatggaa acgcagcagt ggaattgtca tttctctccg aagcagctat atttaaccga
     3241 tggataaata atgcttctct acaacccaca ctgtcagcca cctcaaacct cactgtcctc
     3301 gtgccttccc aacaagctac tgaggacatg gaccaggatg agaaaagctt ctggttgtca
     3361 cagagcaata ttccagccct aataaagtac catatgctac taggcacata cagagtggca
     3421 gatctgcaga ccctgtcttc ttctgacatg ttggcaacat ctttgcaggg caacttcctt
     3481 cacttggcaa aggtggatgg gaatatcaca attgaagggg cctccattgt cgatggggac
     3541 aacgcagcca caaatggagt gatacacatc atcaacaagg tgctggtccc acaaagacgt
     3601 ctaactggct ccttaccaaa cctgctcatg cggctggaac agatgcctga ctattccatc
     3661 ttccggggct acatcattca atataatctg gcgaatgcaa ttgaggctgc cgatgcctac
     3721 acagtgtttg ctccaaacaa caatgccatc gagaattaca tcagggagaa gaaagtcttg
     3781 tctctagagg aggacgtcct ccggtatcat gtggtcctgg aggagaaact cctgaagaat
     3841 gacctgcaca atggcatgca tcgtgagacc atgctgggtt tctcctattt ccttagcttc
     3901 tttctccata atgaccagct ctatgtaaat gaggctccaa taaactacac caatgtagcc
     3961 actgataagg gagtgatcca tggcttggga aaagttctgg aaattcagaa gaacagatgt
     4021 gataataatg acactactat tatacgagga agatgtagga catgctcctc agagctgacc
     4081 tgcccattcg gaactaaatc tctaggtaat gagaagagga gatgcatcta tacctcctat
     4141 ttcatgggaa gacgaaccct gtttattggg tgccagccaa aatgtgtgag aaccgtcatt
     4201 acgagagaat gctgtgccgg cttctttggc ccccaatgcc agccctgccc agggaatgcc
     4261 cagaatgtct gctttggtaa tggcatctgt ttggatggag tgaatggcac aggtgtgtgt
     4321 gagtgtgggg agggcttcag cggcacagcc tgcgagacct gcaccgaggg caagtacggc
     4381 atccactgtg accaagcatg ttcttgtgtc catgggagat gcaaccaagg acccttggga
     4441 gatggctcct gtgactgtga tgttggctgg cgaggagtgc attgtgacaa tgcaaccaca
     4501 gaagacaact gcaatgggac atgccatacc agcgccaact gcctcaccaa ctcagatggt
     4561 acagcttcat gcaagtgtgc agcaggattc caaggaaacg ggaccatctg cacagcaatc
     4621 aatgcctgtg agatcagcaa tggaggttgc tctgccaagg ctgactgtaa gagaaccacc
     4681 ccaggaaggc gagtgtgcac gtgcaaagca ggctacacgg gtgatggcat tgtgtgcctg
     4741 gaaatcaacc cgtgtttgga gaaccatggt ggctgtgaca agaatgcgga gtgcacacag
     4801 acaggaccca accaggctgc ctgtaactgt ttgccagcat acactggaga tggaaaggtc
     4861 tgcacactca tcaatgtctg cttaactaaa aatggcggct gtagtgaatt tgccatctgc
     4921 aaccacactg ggcaagtaga aaggacttgt acttgcaagc caaactacat tggagatgga
     4981 tttacctgcc gcggcagcat ttatcaggag cttcccaaga acccgaaaac ttcccagtat
     5041 ttcttccagt tgcaggagca tttcgtgaaa gatctggtcg gcccaggccc cttcactgtt
     5101 tttgcacctt tatctgcagc ctttgatgag gaagctcggg ttaaagactg ggacaaatac
     5161 ggtttaatgc cccaggttct tcggtaccat gtggtcgcct gccaccagct gcttctggaa
     5221 aacctgaaat tgatctcaaa tgctacttcc ctccaaggag agccaatagt catctccgtc
     5281 tctcagagca cggtgtatat aaacaataag gctaagatca tatccagtga tatcatcagt
     5341 actaatggga ttgttcatat catagacaaa ttgctatctc ccaaaaattt gcttatcact
     5401 cccaaagaca actctggaag aattctgcaa aatcttacga ctttggcaac aaacaatggc
     5461 tacatcaaat ttagcaactt aatacaggac tcaggtttgc tgagtgtcat caccgatccc
     5521 atccacaccc cagtcactct cttctggccc accgaccaag ccctccatgc cctacctgct
     5581 gaacaacagg acttcctgtt caaccaagac aacaaggaca agctgaagga gtatttgaag
     5641 tttcatgtga tacgagatgc caaggtttta gctgtggatc ttcccacatc cactgcctgg
     5701 aagaccctgc aaggttcaga gctgagtgtg aaatgtggag ctggcaggga catcggtgac
     5761 ctctttctga atggccaaac ctgcagaatt gtgcagcggg agctcttgtt tgacctgggt
     5821 gtggcctacg gcattgactg tctgctgatt gatcccaccc tggggggccg ctgtgacacc
     5881 tttactactt tcgatgcctc gggggagtgt gggagctgtg tcaatactcc cagctgccca
     5941 aggtggagta aaccaaaggg tgtgaagcag aagtgtctct acaacctgcc cttcaagagg
     6001 aacctggaag gctgccggga gcggtgcagc ctggtgatac agatccccag gtgctgcaag
     6061 ggctacttcg ggcgagactg tcaggcctgc cctggaggac cagatgcccc gtgtaataac
     6121 cggggtgtct gccttgatca gtactcggcc accggagagt gtaaatgcaa caccggcttc
     6181 aatgggacgg cgtgtgagat gtgctggccg gggagattcg ggcctgattg tctgccctgt
     6241 ggctgctcag accacggaca gtgcgatgat ggcatcacgg gctccgggca gtgcctctgt
     6301 gaaacggggt ggacaggccc ctcgtgtgac actcaggcag ttttgcctgc agtgtgtacg
     6361 cctccttgtt ctgctcatgc cacctgtaag gagaacaaca cgtgtgagtg taacctggat
     6421 tatgaaggtg acggaatcac atgcacagtt gtggatttct gcaaacagga caacgggggc
     6481 tgtgcaaagg tggccagatg ctcccagaag ggcacgaagg tctcctgcag ctgccagaag
     6541 ggatacaaag gggacgggca cagctgcaca gagatagacc cctgtgcaga cggccttaac
     6601 ggagggtgtc acgagcacgc cacctgtaag atgacaggcc cgggcaagca caagtgtgag
     6661 tgtaaaagtc actatgtcgg agatgggctg aactgtgagc cggagcagct gcccattgac
     6721 cgctgcttac aggacaatgg gcagtgccat gcagacgcca aatgtgtcga cctccacttc
     6781 caggatacca ctgttggggt gttccatcta cgctccccac tgggccagta taagctgacc
     6841 tttgacaaag ccagagaggc ctgtgccaac gaagctgcga ccatggcaac ctacaaccag
     6901 ctctcctatg cccagaaggc caagtaccac ctgtgctcag caggctggct ggagaccggg
     6961 cgggttgcct accccacagc cttcgcctcc cagaactgtg gctctggtgt ggttgggata
     7021 gtggactatg gacctagacc caacaagagt gaaatgtggg atgtcttctg ctatcggatg
     7081 aaagatgtga actgcacctg caaggtgggc tatgtgggag atggcttctc atgcagtggg
     7141 aacctgctgc aggtcctgat gtccttcccc tcactcacaa acttcctgac ggaagtgctg
     7201 gcctattcca acagctcagc tcgaggccgt gcatttctag aacacctgac tgacctgtcc
     7261 atccgcggca ccctctttgt gccacagaac agtgggctgg gggagaatga gaccttgtct
     7321 gggcgggaca tcgagcacca cctcgccaat gtcagcatgt ttttctacaa tgaccttgtc
     7381 aatggcacca ccctgcaaac gaggctggga agcaagctgc tcatcactgc cagccaggac
     7441 ccactccaac cgacggagac caggtttgtt gatggaagag ccattctgca gtgggacatc
     7501 tttgcctcca atgggatcat tcatgtcatt tccaggcctt taaaagcacc ccctgccccc
     7561 gtgaccttga cccacactgg cttgggagca gggatcttct ttgccatcat cctggtgact
     7621 ggggctgttg ccttggctgc ttactcctac tttcggataa accggagaac aatcggcttc
     7681 cagcattttg agtcggaaga ggacattaat gttgcagctc ttggcaagca gcagcctgag
     7741 aatatctcga accccttgta tgagagcaca acctcagctc ccccagaacc ttcctacgac
     7801 cccttcacgg actctgaaga acggcagctt gagggcaatg accccttgag gacactgtga
     7861 gggcctggac gggagatgcc agccatcact cactgccacc tgggccatca actgtgaatt
     7921 ctcagcacca gttgcctttt aggaacgtaa agtcctttaa gcactcagaa gccatacctc
     7981 atctctctgg ctgatctggg ggttgtttct gtgggtgaga gatgtgttgc tgtgcccacc
     8041 cagtacagct tcctcctctg accctttggc tcttcttcct ttgtactctt cagctggcac
     8101 ctgctccatt ctgccctaca tgatgggtaa ctgtgatctt tcttccctgt tagattgtaa
     8161 gcctccgtct ttgtatccca gcccctagcc cagtgcctga cacaggaact gtgcacaata
     8221 aaggtttatg gaacagaaac aaa
//
