LOCUS       NM_001050               7685 bp    mRNA    linear   PRI 11-DEC-2024
DEFINITION  Homo sapiens somatostatin receptor 2 (SSTR2), mRNA.
ACCESSION   NM_001050
VERSION     NM_001050.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7685)
  AUTHORS   Sagie,N., Romanov,E., Kezerle,Y., Meirovitz,A. and Sheva,K.
  TITLE     Expression Analysis of SSTR 1, 2 and 3 in Small-cell Lung Cancer
            Patients as Targets for Future Peptide Receptor Radionuclide
            Therapy
  JOURNAL   Anticancer Res 44 (9), 3807-3812 (2024)
   PUBMED   39197921
  REMARK    GeneRIF: Expression Analysis of SSTR 1, 2 and 3 in Small-cell Lung
            Cancer Patients as Targets for Future Peptide Receptor Radionuclide
            Therapy.
REFERENCE   2  (bases 1 to 7685)
  AUTHORS   Kim,J.Y., Kim,J., Kim,Y.I., Yang,D.H., Yoo,C., Park,I.J.,
            Ryoo,B.Y., Ryu,J.S. and Hong,S.M.
  TITLE     Somatostatin receptor 2 (SSTR2) expression is associated with
            better clinical outcome and prognosis in rectal neuroendocrine
            tumors
  JOURNAL   Sci Rep 14 (1), 4047 (2024)
   PUBMED   38374188
  REMARK    GeneRIF: Somatostatin receptor 2 (SSTR2) expression is associated
            with better clinical outcome and prognosis in rectal neuroendocrine
            tumors.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7685)
  AUTHORS   Fan,S., Zheng,H., Zhan,Y., Luo,J., Zang,H., Wang,H., Wang,W. and
            Xu,Y.
  TITLE     Somatostatin receptor2 (SSTR2) expression, prognostic implications,
            modifications and potential therapeutic strategies associates with
            head and neck squamous cell carcinomas
  JOURNAL   Crit Rev Oncol Hematol 193, 104223 (2024)
   PUBMED   38036157
  REMARK    GeneRIF: Somatostatin receptor2 (SSTR2) expression, prognostic
            implications, modifications and potential therapeutic strategies
            associates with head and neck squamous cell carcinomas.
            Review article
REFERENCE   4  (bases 1 to 7685)
  AUTHORS   Gillis,A., Zheng-Pywell,R., McLeod,C., Wang,D., Ness,J.M.,
            Guenter,R., Whitt,J., Prolla,T.A., Chen,H., Gonzalez,M.L., Rose,B.,
            Lloyd,R.V., Jaskula-Sztul,R. and Lin,D.
  TITLE     Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone
            Receptor Expression in Oncocytic Thyroid Neoplasms: Implications
            for Prognosis and Treatment
  JOURNAL   Mod Pathol 36 (12), 100332 (2023)
   PUBMED   37716507
  REMARK    GeneRIF: Somatostatin Receptor Type 2 and Thyroid-Stimulating
            Hormone Receptor Expression in Oncocytic Thyroid Neoplasms:
            Implications for Prognosis and Treatment.
REFERENCE   5  (bases 1 to 7685)
  AUTHORS   Klomp,M.J., Refardt,J., van Koetsveld,P.M., Campana,C., Dalm,S.U.,
            Dogan,F., van Velthuysen,M.F., Feelders,R.A., de Herder,W.W.,
            Hofland,J. and Hofland,L.J.
  TITLE     Epigenetic regulation of SST2 expression in small intestinal
            neuroendocrine tumors
  JOURNAL   Front Endocrinol (Lausanne) 14, 1184436 (2023)
   PUBMED   37223009
  REMARK    GeneRIF: Epigenetic regulation of SST2 expression in small
            intestinal neuroendocrine tumors.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7685)
  AUTHORS   Reubi,J.C., Waser,B., Schaer,J.C. and Markwalder,R.
  TITLE     Somatostatin receptors in human prostate and prostate cancer
  JOURNAL   J Clin Endocrinol Metab 80 (9), 2806-2814 (1995)
   PUBMED   7673428
REFERENCE   7  (bases 1 to 7685)
  AUTHORS   Kagimoto,S., Yamada,Y., Kubota,A., Someya,Y., Ihara,Y., Yasuda,K.,
            Kozasa,T., Imura,H., Seino,S. and Seino,Y.
  TITLE     Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase
            in the presence of Gi alpha 1 protein
  JOURNAL   Biochem Biophys Res Commun 202 (2), 1188-1195 (1994)
   PUBMED   7914078
REFERENCE   8  (bases 1 to 7685)
  AUTHORS   Fujita,T., Yamaji,Y., Sato,M., Murao,K. and Takahara,J.
  TITLE     Gene expression of somatostatin receptor subtypes, SSTR1 and SSTR2,
            in human lung cancer cell lines
  JOURNAL   Life Sci 55 (23), 1797-1806 (1994)
   PUBMED   7968260
REFERENCE   9  (bases 1 to 7685)
  AUTHORS   Patel,Y.C., Greenwood,M., Kent,G., Panetta,R. and Srikant,C.B.
  TITLE     Multiple gene transcripts of the somatostatin receptor SSTR2:
            tissue selective distribution and cAMP regulation
  JOURNAL   Biochem Biophys Res Commun 192 (1), 288-294 (1993)
   PUBMED   8386508
REFERENCE   10 (bases 1 to 7685)
  AUTHORS   Yamada,Y., Post,S.R., Wang,K., Tager,H.S., Bell,G.I. and Seino,S.
  TITLE     Cloning and functional characterization of a family of human and
            mouse somatostatin receptors expressed in brain, gastrointestinal
            tract, and kidney
  JOURNAL   Proc Natl Acad Sci U S A 89 (1), 251-255 (1992)
   PUBMED   1346068
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC097641.6, BC019610.1 and
            BC000256.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_001050.2.
            
            Summary: Somatostatin acts at many sites to inhibit the release of
            many hormones and other secretory proteins. The biologic effects of
            somatostatin are probably mediated by a family of G protein-coupled
            receptors that are expressed in a tissue-specific manner. SSTR2 is
            a member of the superfamily of receptors having seven transmembrane
            segments and is expressed in highest levels in cerebrum and kidney.
            [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.210081.1,
                                           SRR3476690.1098190.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357585.4/ ENSP00000350198.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC097641.6         72208-72218         c
            12-1399             BC019610.1         1-1388
            1400-3007           BC000256.1         740-2347
            3008-7685           AC097641.6         60595-65272         c
FEATURES             Location/Qualifiers
     source          1..7685
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.1"
     gene            1..7685
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="somatostatin receptor 2"
                     /db_xref="GeneID:6752"
                     /db_xref="HGNC:HGNC:11331"
                     /db_xref="MIM:182452"
     exon            1..279
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /inference="alignment:Splign:2.1.0"
     exon            280..7685
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..1481
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="SS2R; SRIF-1"
                     /codon_start=1
                     /product="somatostatin receptor type 2"
                     /protein_id="NP_001041.1"
                     /db_xref="CCDS:CCDS11691.1"
                     /db_xref="GeneID:6752"
                     /db_xref="HGNC:HGNC:11331"
                     /db_xref="MIM:182452"
                     /translation="MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNA
                     VLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQ
                     VALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAK
                     MITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFL
                     VPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFN
                     VSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSG
                     TDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI"
     regulatory      6026..6031
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="hexamer: AATAAA"
     polyA_site      6051
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="major polyA site"
     regulatory      7660..7665
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="hexamer: ATTAAA"
     polyA_site      7685
                     /gene="SSTR2"
                     /gene_synonym="SST2"
                     /note="major polyA site"
ORIGIN      
        1 agtcccagcg gcgcagccac ccatgcgcgc gcgctcgcaa gaccaccagc gcccagagcc
       61 ccagtctgag gcttggcgcc gggggtctgc gggcgagggg agctctctac gtgcgagggg
      121 ctagcgggag ccggcacaag agggtcgagg agccaggaac cccaaacgtc cggcgccagg
      181 cgctagccaa gctgctgcgc gccccggcgc ccagctggct cggggacagc cgctgggtgt
      241 cggagaccgg agctagcgga ttgcagcgga aaagcaaaga tgtcacactg gatccttggc
      301 ctccagggtc cattaaggtg agaataagat ctctgggctg gctggaacta gcctaagact
      361 gaaaagcagc catggacatg gcggatgagc cactcaatgg aagccacaca tggctatcca
      421 ttccatttga cctcaatggc tctgtggtgt caaccaacac ctcaaaccag acagagccgt
      481 actatgacct gacaagcaat gcagtcctca cattcatcta ttttgtggtc tgcatcattg
      541 ggttgtgtgg caacacactt gtcatttatg tcatcctccg ctatgccaag atgaagacca
      601 tcaccaacat ttacatcctc aacctggcca tcgcagatga gctcttcatg ctgggtctgc
      661 ctttcttggc tatgcaggtg gctctggtcc actggccctt tggcaaggcc atttgccggg
      721 tggtcatgac tgtggatggc atcaatcagt tcaccagcat cttctgcctg acagtcatga
      781 gcatcgaccg atacctggct gtggtccacc ccatcaagtc ggccaagtgg aggagacccc
      841 ggacggccaa gatgatcacc atggctgtgt ggggagtctc tctgctggtc atcttgccca
      901 tcatgatata tgctgggctc cggagcaacc agtgggggag aagcagctgc accatcaact
      961 ggccaggtga atctggggct tggtacacag ggttcatcat ctacactttc attctggggt
     1021 tcctggtacc cctcaccatc atctgtcttt gctacctgtt cattatcatc aaggtgaagt
     1081 cctctggaat ccgagtgggc tcctctaaga ggaagaagtc tgagaagaag gtcacccgaa
     1141 tggtgtccat cgtggtggct gtcttcatct tctgctggct tcccttctac atattcaacg
     1201 tttcttccgt ctccatggcc atcagcccca ccccagccct taaaggcatg tttgactttg
     1261 tggtggtcct cacctatgct aacagctgtg ccaaccctat cctatatgcc ttcttgtctg
     1321 acaacttcaa gaagagcttc cagaatgtcc tctgcttggt caaggtgagc ggcacagatg
     1381 atggggagcg gagtgacagt aagcaggaca aatcccggct gaatgagacc acggagaccc
     1441 agaggaccct cctcaatgga gacctccaaa ccagtatctg aactgcttgg ggggtgggaa
     1501 agaaccaagc catgctctgt ctactggcaa tgggctccct acccacactg gcttcctgcc
     1561 tcccacccct cacacctggc ttctagaata gaggattgct cagcatgagt ccaattcaga
     1621 gaacggtgtt tgagtcagct tgtctgattg aatgataatg tgctaaattg attacctccc
     1681 ccttaaagcg aacactgaaa tgcaggtaga caattcaaag tctggagaag agggatcatg
     1741 cctggatatg atctttagaa acaacaaaaa tagaaaaaaa taagtatctg tgtgtttgtg
     1801 tattgaaaac tcaatatgta atcttgtgtt tttatatgta tacttgtata ttcctattta
     1861 ttctctgtat aggcattacc tacgttcctg tgtttacata cacaagtagc aaattcgagt
     1921 atgcatagtg tagatggaca tttgccacaa cacactgccc gcagaaatgg acttaccgtg
     1981 aagccaataa agttcaagct tcagggatct ctcttgcacg ggccttgcca aggcccagga
     2041 gggacttggg cagtatgttc atgtggtcat atgtttttgt aaaaaattgt gaaagtaaga
     2101 tatgtttgta ttgtttttct taaagaggaa cctcgtataa gcttcaagcc tcacaaacct
     2161 tctagcctct gcccttgggg atttgcttca ttaatttcag gcaagtgagg tcaatgtaag
     2221 aagggaaagg gagaagatat ttgaagaacc agaatgtaaa ttcatgtgtt tccacttctc
     2281 agatatagtc agagaattat tcatttgccc aaaaggactt aagtggttgt ggtcatccat
     2341 cattgtattt atcaagacaa agccaacttt gttataagat tgcatttttt tcttttcaaa
     2401 ttgctttagt ttttcttagg gagctatgag ggggaaaaat cactaacatg aaaggcaaaa
     2461 aatggactat gattcctgtg gggaaacaat ttcattctct ccatcgtgaa aataagtgaa
     2521 taagagtgaa gcaaaattac acctttatga gaaaccataa aattgttttt atttttcagg
     2581 ccagacatag cttcctaatg aaagaaaatg gaaatgtaat tcgacgactc ctcaaagggg
     2641 actttagagg acttcataca aagctgggca ttaagaaaac cacaatgcat ggccgggcgt
     2701 ggtggcttac acctgtaatc ccagcacttt gggaggccga ggtgggtgga tcacccgagg
     2761 tcaggagttc gagaccagcc tggccaacat ggtgaaaccc catcactact aaaaatatgt
     2821 aaattagtcg ggcgtggtgt cacgtgcctg taatcctagc tgctcgggag gctgaggcag
     2881 gagaatcact tgaacttggg aggtggaggt tgcagtaagc tgagattgtg ccactgcact
     2941 ctagcctgag caacaagagc aaaactcagt ctcaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3001 aaaaaaaaag gaaaaccaca atgcgtacta aagaccagaa gacattgttc acaaaacaaa
     3061 agcaccctca cctgccaatg aatatgcagc gtgcaggggg tgtggtgtga gtgttggtgg
     3121 ggccccacct ctcggagata ctgctgtgct gccttcctca ctgactgtat acatagtaac
     3181 tgtcatatct ttaatgccat ggactcactg agccgctctg caaggactat tgtagacagg
     3241 cacttcacac cataaagtgg catttttttc gttccccaaa ctgacattta caagcgataa
     3301 gaaaagagac aatatccatt tcattgactg atcattttct agagtatgaa gaaatacaca
     3361 cctgggtgtc tgcaaggatg tcatcatctt tgggtttcat ctgagagcat cactcagcat
     3421 ctcacacata gatgttacca tatttttaaa tgagctttcc tcatccggct ccctaagcaa
     3481 gcgctgttgg ccggtgggag tgactaagtg ctccacctgt gggtgtcctt cttaatgtgc
     3541 tgcttttgtt ctgtataaat tcacaccacc tcactcccaa aagtacttcc tgtggctcag
     3601 aaaaatatgt tcaataagat tttggataga taaatccata caaaaataaa aagaggtata
     3661 gttataaaac aagactacag aaaaagttgt ggcagaaatt gcatgcagga aaatcccaca
     3721 ccattagtaa aagtaaggtc aactgtaagt tcagctcagg gcttcctagc agccatgttt
     3781 agcgaagtgt gatttttttt tttaaacaaa aacaagcaaa gatttggaag aaaatgcttt
     3841 agacctaact ttacaattat tataacataa gatgttccag ggtccttgaa taaatgctga
     3901 gttttaggga aatgattcca agggaccaag aattggtaga aataatttca aggcagagaa
     3961 gactaattct acaggccggg cgtggtggct tatgcctgta atcccacact ttgggaggct
     4021 gaggtgggtg gattgcctga ggtcaagagt tcaagaccag cctggccaac atggtgaaac
     4081 cctgtctcta ctaaaaatac aaaaaattac ccaggcatgg tggcgggcgc ctgtaatccc
     4141 agctacttgg gaggctgaga caggagaatg gcttgaaccc aggaggtgga gattgcggtg
     4201 agctgagatc gtgccattgc actccagcct gggcaacaag agcgaaactt catctcaaaa
     4261 aaaaaaaaca aagactaatt ctatagtacc catgaccctg caaccagaga aactgcctgt
     4321 agggaggcca gagtccaaag cagccacctg taacctgaaa atgaaacgca gacccaggca
     4381 tctgtgggtc ttcatcagca ggatgaccat tctaaggcta aaagacaggc ctttaaatct
     4441 gatgctataa ttccatccaa atacacagtt aggtttctac catagggaaa gctattctct
     4501 actttttgaa gtatctgttt caaagataac ttgctctctg gttctctttt atctaaaaga
     4561 gagaatcaac atgctaattt aaaggttaac atcattttaa ttcaaaaatt ttagtctcca
     4621 ttccatattt aatgatgaag acaaatctgc tgggtgctgg gagggaataa aaagtaatgc
     4681 accccattga tttcagagta tctgatcact tgggttatgc aagctgctac ttacccgcca
     4741 ttagcatggg tagttaagtg ctgattaaac ctaagtggac tcagtgaaaa agatattggg
     4801 aaaaataata tgatattgtg gcctatgttg aatgatgtta gcttgtgttt cagtaacaga
     4861 gttgggtaat actggacgtg tagatgaagc tttagcaggg ctgggcacgg tggctcatgc
     4921 ctgtaatccc agcactttgg gaggctgagg cgggtggatt acctgaggtc aggagttcaa
     4981 gaccagcctg gccaacatgg ggaaaccctg tctctactaa gaatacaaaa attagctggg
     5041 tgtggtggcg tgtgcctgta atcccagcta ctcaggaggc tgagacagga gaatcgcttg
     5101 aacccgggag gcgaaggttg cagtgagcca agatcgcgcc actgcacttc agcctgggtg
     5161 acagcacaag actccatctc aaaaaaaaaa aaaaaaggaa gaagaaaaag aaacttaagt
     5221 ggggttcata catagcatgg cagagggaca ctggagaata aaatggcatg cagagaggaa
     5281 cacgcgggcc agtggatgag gcttctagac ctggcagtga actggagtct atttgcttac
     5341 acaaatttaa ccttctctcc atgatggaat acaagtgttt cttgccaaaa ctcgcagccc
     5401 cagctgccct agatgaggag caccgtgctg gaaaagtgca caggctgatc acagagacag
     5461 gtaggaagca atggactgtt aaaatgcatg ttccgggctg gggatggtgg ctcacacctg
     5521 tgatctcagc actttgggag gccgaggctg gggaatcgct tgagcccagg attttgagac
     5581 tagcctaggc aatatggtga gaccctgccc ttaaaaaaaa aaaagaaaag aaaagaaaag
     5641 aaaaaaagat tcatattcct gatcagctct gaatgtgact attcaatgaa gacagtaaag
     5701 ttacagtgta aggcacacat gacctttggc cttgctaaag aagagtggct gaaggtctag
     5761 caaattaatg cttgtcttag gttacctgtt gatttaaaaa caacaacaac aaaaacccat
     5821 aaaaatagta aaatataaaa acaaattagt gttttataga ccctggggaa aagaattttc
     5881 agcaaagtac aaaaatttaa agcattcctt tctttaattt tgtaattctt tactgtagaa
     5941 cagctcaaaa tatcagttct gttttaagta acagaattga taactgagca gggaaacgta
     6001 atttggattg taaaattctt gctttaataa aaattcttta aacagtcaaa atagaaagaa
     6061 agaaagaaag gtggcaagag aattatcaaa agtttccata gatggttggg aagatctgat
     6121 tagtgtttcc aaaatgctta tcattctaag aatcccaata gctggcaagc caagcagtgg
     6181 aacttatagt aacaacaatc aatcacttgt ctcatcccac atttttgcca aattcaaaaa
     6241 caccaaattt cccatcaaat gttctgtcag agtaaacctt tacctaagtg cttgttttgc
     6301 ttttaatatg tgaatttctg ggaacattcc catgggcagc ctctaatttt tttttttttt
     6361 ttttgagaca gagtttcgct ttttcaccca ggctggagcg cagtggcacg atcttggctc
     6421 actgcaacct ccacctaccg gattcaagtg attctcctgc ctcagcctcc caagtagcag
     6481 ggactacagg cacgtgccac cacgcccagc taatttttgt atttttagtg gagatgggtt
     6541 tttgccatgt tggccaggca ggtcttgaac tcttgacctc aggtgatccg cctgcctcag
     6601 tgtcccaaag tgttgggatt acaggcacga gccaccgcgc tcagccaatt tttcctcaac
     6661 tctctctttc ctggacgggc tgcgttgggg ggaggtgcag ggaaagaaca cctctttgct
     6721 tagacattgg tgtcgacagt ggggatacta agttcatctc ctgatcctgc taggcctgga
     6781 agcaggaaag aaatgtcctg gttagagata aaattgttct atccttttag aaaagcctgt
     6841 taaggaatat gatgcaaagc caccttcgac gaaatctgaa atgatacccc acagccttgt
     6901 ccaccccaat tattcagtga cagggctcca gttgcttaag ccatagagaa ggcccctttg
     6961 cagtgggagt cactgaagac agaaagggaa gcccaggatg aacccagtcc taagggctgc
     7021 tgggggccac caaataagac tgttttagcc ctggacacag agggagacac agtcatccca
     7081 gatccttaca aagaatacat tgccaaggac cccgaaggaa atctgcttgt cttaagagag
     7141 gaagacccac gaccagctct ctgggactac ctgtcaactc agcaggtgca gccagggagc
     7201 agccatgctt cttctgccct cccagtaggc tgggctatca gttcctggga ggggtcctgt
     7261 ccccatgtaa ggggatatgt acattgctga gtacgctgat atctttttca tgggtatgat
     7321 tttttaacaa gaaagctaaa tggttctcgt gtaacataac tgatatagtt tggctgtgtc
     7381 cccacccaaa tcttatcttg aactgcagct cccataatcc ccaggtgttg tgggagggac
     7441 ccagtgggag gtaattgaat catgggggtg gttaccgcca tgctgttctc gtgatagcga
     7501 gtgagttctc acgagatctg atggttttat aaggggcttt ccccctcctt cgctctgcac
     7561 ttctccttgc tgccatgcga agaaggatgt gtttgcttcc ccttctgcca tgattgtaag
     7621 tttcctgagg cctccccagc catgttaaac tttgagttaa ttaaacctct ttcctttata
     7681 aatta
//
