LOCUS       XM_047428008            6118 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SLIT-ROBO Rho GTPase activating protein 2B
            (SRGAP2B), transcript variant X5, mRNA.
ACCESSION   XM_047428008
VERSION     XM_047428008.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6118
                     /gene="SRGAP2B"
                     /gene_synonym="SRGAP2L; SRGAP2P2"
                     /note="SLIT-ROBO Rho GTPase activating protein 2B; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 5 ESTs, 2004 long SRA reads, 1 Protein, and
                     94% coverage of the annotated genomic feature by RNAseq
                     alignments, including 24 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:647135"
                     /db_xref="HGNC:HGNC:35237"
                     /db_xref="MIM:614703"
     CDS             329..1246
                     /gene="SRGAP2B"
                     /gene_synonym="SRGAP2L; SRGAP2P2"
                     /codon_start=1
                     /product="SLIT-ROBO Rho GTPase-activating protein 2B
                     isoform X3"
                     /protein_id="XP_047283964.1"
                     /db_xref="GeneID:647135"
                     /db_xref="HGNC:HGNC:35237"
                     /db_xref="MIM:614703"
                     /translation="MKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVK
                     QEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLL
                     ALEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIE
                     NAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELLQRCQQ
                     LQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETF
                     MSKPSIAKRRANQQETEQFYFTVRECYGF"
ORIGIN      
        1 accaaggacc agcaattcaa atgtacaggc agcatgtgac tttccgggtc tcctttcgac
       61 tccagagtca ttccctctca gctggtatat ttttgatttc catagaaatc tttcagtttc
      121 cctaaaaagg aaggatcaga atgttctctc tccagtcaac tgctggaatc tcctcttaaa
      181 ccaggtgaag cgggaaagca gggaccatac caccctgagt gacatctacc tgaataatat
      241 cattcctcga tttgtacaag tcagcgagga ctcaggaaga ctctttaaaa agagtaaaga
      301 agtcggccag cagctccaag atgatttgat gaaggtcctg aacgagctct actcggtcat
      361 gaagacatat cacatgtaca atgccgacag catcagtgct cagagcaaac taaaggaggc
      421 ggagaagcag gaggagaagc aaattggtaa atcggtaaag caggaggacc ggcagacccc
      481 acgctcccct gactccacgg ccaacgttcg cattgaggag aaacatgtcc ggaggagctc
      541 agtgaagaag attgagaaga tgaaggagaa gcgccaagcc aagtacacgg agaataagct
      601 gaaggccatc aaagcccgga atgagtactt gctggctttg gaggcaacca atgcatctgt
      661 cttcaagtac tacatccatg acctatctga ccttattgat tgttgtgact taggctacca
      721 tgcaagtctg aaccgggctc tacgcacctt cctctctgct gagttaaacc tggaacagtc
      781 gaagcatgag ggtctggatg ccatcgagaa tgcagtagaa aacctggatg ccaccagtga
      841 caagcagcgc ctcatggaga tgtacaacaa cgtcttctgc ccccctatga agtttgagtt
      901 tcagccccac atgggggata tggcttccca gctctgtgcc cagcagcctg tccagagtga
      961 gctgctacag agatgccaac aactgcagtc tcgcttatcc actctaaaga ttgaaaacga
     1021 agaggtaaag aagacaatgg aggccaccct gcaaaccatc caggacattg tgactgtcga
     1081 ggacttcgat gtgtctgact gcttccagta cagcaactcc atggagtccg tcaagtccac
     1141 ggtctctgaa accttcatga gcaagcccag cattgctaag aggagagcca accagcaaga
     1201 gacagagcag ttttatttca cagtgaggga gtgctatggc ttttaaagag cgtcagcatg
     1261 cactgcagca ctcaagggag atttggaact cagagtcctt gttaagtgtc tgaaggacag
     1321 gcgttgaata tcttagatac gaatgtgggc atactcagag accatcccta cagttaaagg
     1381 tgcaaacatt aaaagttgta tatgtctaac agggatccgc ccaagagaaa ggatgctccc
     1441 aagtatacaa ctaagaagat tttctttttt aagaaatttt taactagcta gtaggctttc
     1501 actggaaagt ttccttctca ggcacagggg atcctgaaag gggaacttca tcttttagtt
     1561 cttggagagt acatacaaat attcataata acacatattt tgtttataaa aatctataat
     1621 ctcttctagg tgatatgatg acattatttt ataactttta ttgttgggaa actatttttt
     1681 ctaattattg ctaaaactta aaggatgggt aatatgcagc attactattt tgcacataat
     1741 tccaaaacat cgtattttct tattcatgta tctctagtct tcttttagac agttggaccc
     1801 ttttttctct tttttttttt tttttttttt ttttaagtat tgttaacaat cctttggaag
     1861 tcactactgg tctttgtgtg ctgcttttta ataattgagt tattttgagc ttgccaagta
     1921 ggatctattg cctggactaa aatttatttc ctaatcttct gatgaccaag aaaggaaaaa
     1981 ttaagtttgc agatgtgaga tgaaatatag ccagtgaata tgcatactga ttctgaatga
     2041 aaggaattaa cttttcagtc aagaaacagt ctgcatgcag taaattgaat ttttcctgca
     2101 actggaatga tttgtttaat tcttctttga acactgccct ttctccagta agaacactaa
     2161 tgatttgcta atatttttta aagaaatctg tttttttaat tagttaagct cagacttcct
     2221 cttatttttt atcctagaga aaactgctaa aagggaatga tatatcagta ctattcttct
     2281 aaaacaactt tttaaaaatg attatacaaa gccaaatatg ctcattatat aaaatttaga
     2341 agcaaaaaga aggaaataaa aattttccat aattctacca gctagagata atggtgttag
     2401 aatatattcc tttctaatct gttttctatg catgcacaaa cacatatgtg agcacatatt
     2461 tataatttta ttctaaaaaa taggatactg ctgtacatat tgttttacaa tctaagtcat
     2521 ataattataa tattctttaa gcatatttat gagtaaaata ttaaaaccta tacaaaaaaa
     2581 taatagaatg gcattttagc tcattcattg atttttataa aatatttaac acactccctg
     2641 gtttgtagtt agcgttcaat aaatgctaaa aatttatctt caccatcatc attaatttat
     2701 ttattaatca ttattaaatt attcattgat cattttttga ggatttacta ttgccagaca
     2761 ctgtgctaca agctgggaat gctgacagta taagataaag agggaaatga tgggggatgg
     2821 gtcatgtaaa gggagaactt tcatttttac ttcatatata tctaagcagt tataataggt
     2881 tgatttttgt aatttaaaaa atgtaaaaat gcatacatgc actagtgcat gaatggcagc
     2941 caggatgagt ggaattggag aagcatcaca cacacagtga cttttgtgtt tgatcttgaa
     3001 gaatgagcga accaggcagg gagtcgggga ggagaatcgc attccttgag gaaagagcag
     3061 catgtgggaa aacataaatg cacgcaataa cctggctcac atgttaagag aactttctga
     3121 ctataatgag ggatgtgttg ctgccccaag cttcattatc taaggagttt gttgaacact
     3181 ctctagaggc ttttaataat aggattgttt agctggtctg tctggactgg ttagatataa
     3241 cactatttaa atgacccaat ctcattacat tgtgaagatt tccatttttt aggttacgta
     3301 agaaattttg gacctaaaaa tcttgcattt taagacagtc tttgtcagaa ttactttttg
     3361 gctctaaatg aattctgtaa catttgtatt ctaaattgac ctttagtaaa agcaggaatg
     3421 gccatattca aactggtaac ctcgcaaatc ctgcccaccc tttcactttc tgtctcaata
     3481 cattgatgtc ctctaaccca tttcctgtct tatgtggctt tagtgccact tatcaaaatt
     3541 gtgtgcaaat ttccttggct aacagtaaca gtttttgtct gggcttgtct agcagtggaa
     3601 ttctgcctga gttcatcatt tttgtgactg gtacttgaag tgcatcagat gattaatttc
     3661 atgataagag ggctttttgg ggtggtgaaa tagacattta tggaaaatgg gatacccaca
     3721 ttaagcaggg tgactacctg tttaccatac aacccacaca aagccaatac aactatagat
     3781 gtgctttatt tagtctgttg cctctgcaaa cattgcccgt gtgtttctct atgcccttca
     3841 aaaacatcag agcagcacat cctggaagat cctatctttt gtaagtttaa gaagcagcct
     3901 cttgtcacag gttgactcct aggtagtgtg cctagtgacc aagagggctg ctaagaaagc
     3961 tttctgacca cttgtggctg tcattggact gatttgccca gatgacatca attgggaatt
     4021 tgaggcatga cctataaaga tcagttgctt gcaagagtct caggaaaata attgtggagt
     4081 taagaaactt gaagcgattt ttaaaaatta cctaacccaa ccttctcatt tgaaaaatta
     4141 aaaaataaat aggccagata tggcagctca tgcctgtaat cccagcgctg tgggagcctg
     4201 aggcgggtgg gtctcttgag gccaggagtt caagaccagc ctggacaaca tggtgaaacc
     4261 ctgtctctac taaaaacaca aaaattagct gagtgtggtg gcaggcgcct gtaatcccag
     4321 ctactcagga ggctaaggtg ggaggattac ttgaaccggg gaggcatagg ttgtagtgag
     4381 ccaagatcgt gtcactgcac tccagcctgg gtgacagagt aagactctgc ctaaaaaaaa
     4441 aaaagaaaga ttaaaaaata aataaatctg ctgggcgtgg tggctcacgc ctgtaatccc
     4501 agcactttgg gaggccgagg cgggcggatc acctgaggtc gggagtttga gaccagcctg
     4561 atcaacatgg agaaacctcg tctctactaa aaacacgaaa aaattagctg ggcgtggtgg
     4621 cgcatgcctc attcacgtac atgggagagt ctacaaagtc acacgtattc ataggttaag
     4681 ccacatgctg acaaatgtca taagaagacc ctacactttt accttggccg atccctcccc
     4741 tcagtgcaag ctctgtgcaa gagtgaactt gaacttcact cagtgcaaga gtgaacacac
     4801 actttgtgcc ggctttaaag aacccagcac aaagccagtc tgcatggcct acagacatat
     4861 tttgctggac aatgattact tgcttttctt tttgtttttc ttgtatttgc ctgtttgatt
     4921 ggctcctgac ataccagaaa atcactgtca aaacattagc ttaacatttg ttaaggaaac
     4981 aaaaagactt cggtgaccac accttataaa ccaaacagtt ttgtaaatca ctttggaaaa
     5041 tttcactaaa aaaaaaaatc cttaacaata taataagtaa agaaaattta aaaccacaaa
     5101 acatcactgt gtttgtaggg ggaggtctga tttacagagt aaccacatag taattataat
     5161 tattagaatg tccagttttc aaaaaacgtt acaaggcata caaagaatgg gaaagtgtgg
     5221 ctcattcaaa ggaacaaaat aaagtgacag aaaatatccc taaagaaacc cagacatcaa
     5281 acttaccaga caaagacttt aaaacaactg tcttcattat actcaaatgt caaaaggaaa
     5341 acataaacaa agaaataaag gaatcagaaa aaatattaaa aagtaggaat atcagcaaag
     5401 agataacaaa ttctggagtg gaaaactaca atgataaaaa tttaaaaatc accagaggga
     5461 tttaagagta tatttgcaca cacagaggaa gccatgaact tgaagagaag aaaatggaaa
     5521 atactctgag aaacagaaag aataaaaaat aaacaatgag cacagactaa tgaatctgtg
     5581 ggacatcatc aaatagacca acattcatat tctagaagga taaattatgt tgttaaaaag
     5641 tttaccattc tttcttttca cctttcttcc ttcttccttc cccctcctcc tcctttttac
     5701 ttttcttcct cttcctttct cttcttcttt ctctccttca ttatcccttt cgctgtctct
     5761 ctttctccct ttctcttttt tcttttcttt caattttctc aattactaag agatgtttaa
     5821 gtacccttag catgttagta gatacggtta tttctccctt tagttctctt ttgagattta
     5881 tagtcactca aataaagaga taacccaaac ataagcgtca caaacaggct ttcataccat
     5941 tcttaatttg gtcctgtaat tcttcattgc tgtattaatt ttctgatgct tttaaggatg
     6001 ttttataaca agttgtgtag ctttttccaa tggaatgttt attctgaatt atctaattca
     6061 tattgtaagt atagagggag tttaacataa aattattaaa ctaatatttg tgaaagaa
//
