LOCUS       XM_005277422            5850 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SLIT-ROBO Rho GTPase activating protein 2B
            (SRGAP2B), transcript variant X4, mRNA.
ACCESSION   XM_005277422
VERSION     XM_005277422.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005277422.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5850
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5850
                     /gene="SRGAP2B"
                     /gene_synonym="SRGAP2L; SRGAP2P2"
                     /note="SLIT-ROBO Rho GTPase activating protein 2B; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 5 ESTs, 1994 long SRA reads, 1 Protein, and
                     93% coverage of the annotated genomic feature by RNAseq
                     alignments, including 84 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:647135"
                     /db_xref="HGNC:HGNC:35237"
                     /db_xref="MIM:614703"
     CDS             58..978
                     /gene="SRGAP2B"
                     /gene_synonym="SRGAP2L; SRGAP2P2"
                     /codon_start=1
                     /product="SLIT-ROBO Rho GTPase-activating protein 2B
                     isoform X2"
                     /protein_id="XP_005277479.1"
                     /db_xref="GeneID:647135"
                     /db_xref="HGNC:HGNC:35237"
                     /db_xref="MIM:614703"
                     /translation="MKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVK
                     QEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLL
                     ALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAI
                     ENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELLQRCQ
                     QLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSET
                     FMSKPSIAKRRANQQETEQFYFTVRECYGF"
ORIGIN      
        1 gggaaatgaa caacttaaaa cagtaaagaa gtcggccagc agctccaaga tgatttgatg
       61 aaggtcctga acgagctcta ctcggtcatg aagacatatc acatgtacaa tgccgacagc
      121 atcagtgctc agagcaaact aaaggaggcg gagaagcagg aggagaagca aattggtaaa
      181 tcggtaaagc aggaggaccg gcagacccca cgctcccctg actccacggc caacgttcgc
      241 attgaggaga aacatgtccg gaggagctca gtgaagaaga ttgagaagat gaaggagaag
      301 cgccaagcca agtacacgga gaataagctg aaggccatca aagcccggaa tgagtacttg
      361 ctggctttgg aggcaaccaa tgcatctgtc ttcaagtact acatccatga cctatctgac
      421 cttattgatc agtgttgtga cttaggctac catgcaagtc tgaaccgggc tctacgcacc
      481 ttcctctctg ctgagttaaa cctggaacag tcgaagcatg agggtctgga tgccatcgag
      541 aatgcagtag aaaacctgga tgccaccagt gacaagcagc gcctcatgga gatgtacaac
      601 aacgtcttct gcccccctat gaagtttgag tttcagcccc acatggggga tatggcttcc
      661 cagctctgtg cccagcagcc tgtccagagt gagctgctac agagatgcca acaactgcag
      721 tctcgcttat ccactctaaa gattgaaaac gaagaggtaa agaagacaat ggaggccacc
      781 ctgcaaacca tccaggacat tgtgactgtc gaggacttcg atgtgtctga ctgcttccag
      841 tacagcaact ccatggagtc cgtcaagtcc acggtctctg aaaccttcat gagcaagccc
      901 agcattgcta agaggagagc caaccagcaa gagacagagc agttttattt cacagtgagg
      961 gagtgctatg gcttttaaag agcgtcagca tgcactgcag cactcaaggg agatttggaa
     1021 ctcagagtcc ttgttaagtg tctgaaggac aggcgttgaa tatcttagat acgaatgtgg
     1081 gcatactcag agaccatccc tacagttaaa ggtgcaaaca ttaaaagttg tatatgtcta
     1141 acagggatcc gcccaagaga aaggatgctc ccaagtatac aactaagaag attttctttt
     1201 ttaagaaatt tttaactagc tagtaggctt tcactggaaa gtttccttct caggcacagg
     1261 ggatcctgaa aggggaactt catcttttag ttcttggaga gtacatacaa atattcataa
     1321 taacacatat tttgtttata aaaatctata atctcttcta ggtgatatga tgacattatt
     1381 ttataacttt tattgttggg aaactatttt ttctaattat tgctaaaact taaaggatgg
     1441 gtaatatgca gcattactat tttgcacata attccaaaac atcgtatttt cttattcatg
     1501 tatctctagt cttcttttag acagttggac ccttttttct cttttttttt tttttttttt
     1561 ttttttaagt attgttaaca atcctttgga agtcactact ggtctttgtg tgctgctttt
     1621 taataattga gttattttga gcttgccaag taggatctat tgcctggact aaaatttatt
     1681 tcctaatctt ctgatgacca agaaaggaaa aattaagttt gcagatgtga gatgaaatat
     1741 agccagtgaa tatgcatact gattctgaat gaaaggaatt aacttttcag tcaagaaaca
     1801 gtctgcatgc agtaaattga atttttcctg caactggaat gatttgttta attcttcttt
     1861 gaacactgcc ctttctccag taagaacact aatgatttgc taatattttt taaagaaatc
     1921 tgttttttta attagttaag ctcagacttc ctcttatttt ttatcctaga gaaaactgct
     1981 aaaagggaat gatatatcag tactattctt ctaaaacaac tttttaaaaa tgattataca
     2041 aagccaaata tgctcattat ataaaattta gaagcaaaaa gaaggaaata aaaattttcc
     2101 ataattctac cagctagaga taatggtgtt agaatatatt cctttctaat ctgttttcta
     2161 tgcatgcaca aacacatatg tgagcacata tttataattt tattctaaaa aataggatac
     2221 tgctgtacat attgttttac aatctaagtc atataattat aatattcttt aagcatattt
     2281 atgagtaaaa tattaaaacc tatacaaaaa aataatagaa tggcatttta gctcattcat
     2341 tgatttttat aaaatattta acacactccc tggtttgtag ttagcgttca ataaatgcta
     2401 aaaatttatc ttcaccatca tcattaattt atttattaat cattattaaa ttattcattg
     2461 atcatttttt gaggatttac tattgccaga cactgtgcta caagctggga atgctgacag
     2521 tataagataa agagggaaat gatgggggat gggtcatgta aagggagaac tttcattttt
     2581 acttcatata tatctaagca gttataatag gttgattttt gtaatttaaa aaatgtaaaa
     2641 atgcatacat gcactagtgc atgaatggca gccaggatga gtggaattgg agaagcatca
     2701 cacacacagt gacttttgtg tttgatcttg aagaatgagc gaaccaggca gggagtcggg
     2761 gaggagaatc gcattccttg aggaaagagc agcatgtggg aaaacataaa tgcacgcaat
     2821 aacctggctc acatgttaag agaactttct gactataatg agggatgtgt tgctgcccca
     2881 agcttcatta tctaaggagt ttgttgaaca ctctctagag gcttttaata ataggattgt
     2941 ttagctggtc tgtctggact ggttagatat aacactattt aaatgaccca atctcattac
     3001 attgtgaaga tttccatttt ttaggttacg taagaaattt tggacctaaa aatcttgcat
     3061 tttaagacag tctttgtcag aattactttt tggctctaaa tgaattctgt aacatttgta
     3121 ttctaaattg acctttagta aaagcaggaa tggccatatt caaactggta acctcgcaaa
     3181 tcctgcccac cctttcactt tctgtctcaa tacattgatg tcctctaacc catttcctgt
     3241 cttatgtggc tttagtgcca cttatcaaaa ttgtgtgcaa atttccttgg ctaacagtaa
     3301 cagtttttgt ctgggcttgt ctagcagtgg aattctgcct gagttcatca tttttgtgac
     3361 tggtacttga agtgcatcag atgattaatt tcatgataag agggcttttt ggggtggtga
     3421 aatagacatt tatggaaaat gggataccca cattaagcag ggtgactacc tgtttaccat
     3481 acaacccaca caaagccaat acaactatag atgtgcttta tttagtctgt tgcctctgca
     3541 aacattgccc gtgtgtttct ctatgccctt caaaaacatc agagcagcac atcctggaag
     3601 atcctatctt ttgtaagttt aagaagcagc ctcttgtcac aggttgactc ctaggtagtg
     3661 tgcctagtga ccaagagggc tgctaagaaa gctttctgac cacttgtggc tgtcattgga
     3721 ctgatttgcc cagatgacat caattgggaa tttgaggcat gacctataaa gatcagttgc
     3781 ttgcaagagt ctcaggaaaa taattgtgga gttaagaaac ttgaagcgat ttttaaaaat
     3841 tacctaaccc aaccttctca tttgaaaaat taaaaaataa ataggccaga tatggcagct
     3901 catgcctgta atcccagcgc tgtgggagcc tgaggcgggt gggtctcttg aggccaggag
     3961 ttcaagacca gcctggacaa catggtgaaa ccctgtctct actaaaaaca caaaaattag
     4021 ctgagtgtgg tggcaggcgc ctgtaatccc agctactcag gaggctaagg tgggaggatt
     4081 acttgaaccg gggaggcata ggttgtagtg agccaagatc gtgtcactgc actccagcct
     4141 gggtgacaga gtaagactct gcctaaaaaa aaaaaagaaa gattaaaaaa taaataaatc
     4201 tgctgggcgt ggtggctcac gcctgtaatc ccagcacttt gggaggccga ggcgggcgga
     4261 tcacctgagg tcgggagttt gagaccagcc tgatcaacat ggagaaacct cgtctctact
     4321 aaaaacacga aaaaattagc tgggcgtggt ggcgcatgcc tcattcacgt acatgggaga
     4381 gtctacaaag tcacacgtat tcataggtta agccacatgc tgacaaatgt cataagaaga
     4441 ccctacactt ttaccttggc cgatccctcc cctcagtgca agctctgtgc aagagtgaac
     4501 ttgaacttca ctcagtgcaa gagtgaacac acactttgtg ccggctttaa agaacccagc
     4561 acaaagccag tctgcatggc ctacagacat attttgctgg acaatgatta cttgcttttc
     4621 tttttgtttt tcttgtattt gcctgtttga ttggctcctg acataccaga aaatcactgt
     4681 caaaacatta gcttaacatt tgttaaggaa acaaaaagac ttcggtgacc acaccttata
     4741 aaccaaacag ttttgtaaat cactttggaa aatttcacta aaaaaaaaaa tccttaacaa
     4801 tataataagt aaagaaaatt taaaaccaca aaacatcact gtgtttgtag ggggaggtct
     4861 gatttacaga gtaaccacat agtaattata attattagaa tgtccagttt tcaaaaaacg
     4921 ttacaaggca tacaaagaat gggaaagtgt ggctcattca aaggaacaaa ataaagtgac
     4981 agaaaatatc cctaaagaaa cccagacatc aaacttacca gacaaagact ttaaaacaac
     5041 tgtcttcatt atactcaaat gtcaaaagga aaacataaac aaagaaataa aggaatcaga
     5101 aaaaatatta aaaagtagga atatcagcaa agagataaca aattctggag tggaaaacta
     5161 caatgataaa aatttaaaaa tcaccagagg gatttaagag tatatttgca cacacagagg
     5221 aagccatgaa cttgaagaga agaaaatgga aaatactctg agaaacagaa agaataaaaa
     5281 ataaacaatg agcacagact aatgaatctg tgggacatca tcaaatagac caacattcat
     5341 attctagaag gataaattat gttgttaaaa agtttaccat tctttctttt cacctttctt
     5401 ccttcttcct tccccctcct cctccttttt acttttcttc ctcttccttt ctcttcttct
     5461 ttctctcctt cattatccct ttcgctgtct ctctttctcc ctttctcttt tttcttttct
     5521 ttcaattttc tcaattacta agagatgttt aagtaccctt agcatgttag tagatacggt
     5581 tatttctccc tttagttctc ttttgagatt tatagtcact caaataaaga gataacccaa
     5641 acataagcgt cacaaacagg ctttcatacc attcttaatt tggtcctgta attcttcatt
     5701 gctgtattaa ttttctgatg cttttaagga tgttttataa caagttgtgt agctttttcc
     5761 aatggaatgt ttattctgaa ttatctaatt catattgtaa gtatagaggg agtttaacat
     5821 aaaattatta aactaatatt tgtgaaagaa
//
