LOCUS       XM_011529280            5400 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens serine palmitoyltransferase long chain base
            subunit 3 (SPTLC3), transcript variant X3, mRNA.
ACCESSION   XM_011529280
VERSION     XM_011529280.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000020.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 6, 2016 this sequence version replaced XM_011529280.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
     gene            1..5400
                     /gene="SPTLC3"
                     /gene_synonym="C20orf38; dJ718P11; dJ718P11.1; hLCB2b; LCB
                     3; LCB2B; LCB3; SPT 3; SPT3; SPTLC2L"
                     /note="serine palmitoyltransferase long chain base subunit
                     3; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 5 ESTs, 149 long SRA reads, 1
                     Protein, and 96% coverage of the annotated genomic feature
                     by RNAseq alignments, including 40 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:55304"
                     /db_xref="HGNC:HGNC:16253"
                     /db_xref="MIM:611120"
     CDS             79..1164
                     /gene="SPTLC3"
                     /gene_synonym="C20orf38; dJ718P11; dJ718P11.1; hLCB2b; LCB
                     3; LCB2B; LCB3; SPT 3; SPT3; SPTLC2L"
                     /codon_start=1
                     /product="serine palmitoyltransferase 3 isoform X2"
                     /protein_id="XP_011527582.1"
                     /db_xref="GeneID:55304"
                     /db_xref="HGNC:HGNC:16253"
                     /db_xref="MIM:611120"
                     /translation="MENGQALFPVGGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNS
                     MNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQP
                     RTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGV
                     TEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAE
                     QIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYM
                     PGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGD
                     LLQLKYSRHKKSARPELYDETSFELED"
ORIGIN      
        1 cacctcatcc tggcagaatg ccctctgtgt gggaggggtc ttgcaagctg actcagtgcc
       61 acaggggcca ccctggtcat ggaaaatggg caggcactct tccctgttgg aggcaccttg
      121 gataagcaca aggagttgga ggaccttgtg gctaagttcc tgaatgtgga agcagctatg
      181 gtctttggga tgggattcgc aactaactca atgaatatcc cagcattagt tggaaaggga
      241 tgcctcattt taagtgatga gttaaaccac acatcgcttg tgcttggggc ccgactctca
      301 ggtgcaacca taagaatctt caaacacaac aacacacaaa gcctagagaa gctcctgaga
      361 gatgctgtca tctatggcca gcctcgaacc cgcagagctt ggaaaaagat tctcatcctg
      421 gtggagggtg tctacagcat ggaaggttcc atcgtgcatc tgccccagat catagctcta
      481 aagaagaaat acaaggctta cctctacata gatgaagctc acagtattgg ggccgtgggc
      541 ccaaccggcc ggggtgtcac ggagttcttt ggactagacc ctcatgaagt tgatgtgctc
      601 atgggcacat tcaccaaaag ttttggagct tcaggaggtt acatagctgg aaggaaggac
      661 ctcgtggatt atttacgggt tcactcgcat agtgctgttt atgcttcatc catgagccca
      721 ccgatagcag agcaaatcat cagatcacta aaacttatca tgggactgga tgggaccact
      781 caagggctgc agagagtaca gcaacttgcg aaaaacacaa gatacttcag acaaagactg
      841 caggaaatgg gattcattat ctatggcaat gagaatgctt ctgttgttcc tctgcttctt
      901 tatatgcctg gtaaagtagc ggcttttgca aggcatatgc tagagaaaaa aattggagtg
      961 gtggtcgtgg gatttccagc cactcccctc gcagaagctc gggctcggtt ttgtgtttca
     1021 gcggcacata cccgggagat gttagacacg gttttagaag ctcttgatga aatgggtgat
     1081 ctcttgcaac tgaaatattc ccggcacaag aagtcagcac gtcctgagct ctatgatgag
     1141 acgagctttg aactcgaaga ttaagtttcc tggtcctgaa tgacacataa agactttgcg
     1201 agaaagacct ccctccttgc ctcacaagga atataaatgg atttctcccc cttcctcagg
     1261 acaattttgg ttcccagacc agcttgattg aactgaggga gacgttgttg tttttaatgt
     1321 ctccagcttg gactgcagag acaaaaacat gattccagat ttaagtctct cttcttccaa
     1381 gtattctact agaaatacac acacacacac acacacactt ctgagaatat ttttaatggc
     1441 aataagcctg tgttttagct gctactgtgc agaccctttc agggattcca accaaatgca
     1501 aatgagagaa tttaaaattt ttattcagta agttcactat gtgtttactt attccatctg
     1561 cagatgtaag tgagtgtggt ggacagtagc caccttcctt gttccactca taaaagcatc
     1621 agctagatct catctgtatc atgggaagtt ccaggcagga gggtaaagaa atgttgtttc
     1681 taccatttgt cacatttgga cgtttttcac agacaagtgt caaaagacat agttaatgtt
     1741 tcgaggggga aagcagaact gatcaactgc gactagagac gtctttgaag gaaattttcc
     1801 ttttcctctt gctggtctcc tacagtttta cagctgagct tttgaggttt ggaaaattca
     1861 agatgtttgt ttcataagaa aaggggcaga aagcaagcac aagacacttt taggtctaga
     1921 ctaaaatggt agttacaaca atttgaacct tgttggtgca gtgcacggtg aatgcttacc
     1981 ctgcacagcc tctattacct taaggaatta gttgtcattt tcctattgaa ttttgagtaa
     2041 atggtgaaat tcagtgtcct ttagaatcga ctcccaagac tatatttgaa gaatgcattg
     2101 attcaagaag gacatttaaa agcaaattct gactttttca agaccaacac acttgtttag
     2161 gcctattaaa ttgtactatc acttgttaca tgccctctga attgggagaa agtgggcttg
     2221 cacactttga ggtaactaac tgtaatttac ttgtgttctc tctttcttgc tctccttctc
     2281 aacatgaaca caaacctcta tggaaaagta gcctcttgtt aatctgatct agtttgtatg
     2341 gaaaaagccc atggagaacc ttatctttaa caagctccca gagggtgccc agatttggaa
     2401 attctagaga gcagtggtga ccttttagca aagcttctgt aacagttcga atgagttgca
     2461 gaacattcca ctccatcaaa tgacactgta aacaaatcac ttcaagagag gcttggtttt
     2521 gtgtggcaca gatggaccca agctttcatg ctgtgcactg agatagaaac tccacccgca
     2581 gcgcctgcga tggatggagc agtgtgccct gatgctcaaa gcgtattaaa ggaaaaaaag
     2641 tgatcagcat ggaaagtttt tatggggaaa ttataactcc aagtgggtgc attggtttaa
     2701 aaatggatca caatgataga gttcttcatg aatgtttaca agttgtaagg aataccgtta
     2761 gtgaaagagg aaaagaagtg ggttctgaaa atgcagtttc ccatccaatg attttgataa
     2821 caaaattcca acttttctca atgaaactga tgcagtatta tttgtgcaaa taaaatgtgt
     2881 cataaatatg caaagaaagg gagacatact gttcttatct tgaatatgtg catttaaatg
     2941 aattgtccaa aatgcataaa tgccttgcgt tctataaagg aaacaggagg tcaaaaagac
     3001 agcgagatat ctagtccttc cacaaggtat ggaaagcaat aaacatcttc ctttctttct
     3061 ggatctgtct gtgatgttta cacacacctt cacatctaca cttcaagttt taagccccta
     3121 gacatgtgtc ttcatgagca ggaatgtcca ctattattac tttcatggag gatattgggt
     3181 ctaattcatt gtgggaaact acttacctac ccagcatgga aggcagggag gaagttagtc
     3241 tcttttcatc aagattcaag agtacagggg caatttatta cactgcaatg tacaaaacaa
     3301 aaggacctgt ttctgttaga gagtccatgt tgaatataca ggtatgagaa caactgttga
     3361 tatacaggta taatccaagt agaatgcttc cacagtgcat tagaaggtgc ccaagctcca
     3421 cagggccaat aatattagag tatatgtcat atagaataag gttaattagg agggtgattg
     3481 tgaataatga gatttttaat ttttttaaga aaaagctctc aaatgctagg ctaataagtt
     3541 catgatttta attcatgatt ttaattcatg attaaaatta tttgattatt gagtcttgat
     3601 aattatatca tcaaccatta ccctctacat caccgccccg accttagctc taattatatc
     3661 agagccaaaa atgtgtcttt ggttagatct gttggaaaag agaattttct ataatgttat
     3721 gcgcactcag cccttctgtt cacatttaca cacatgcaca cacacataca catatgcatt
     3781 tttcctttac ggagtaagca actatgaaaa tctggttggt tgagaaataa atggaagatg
     3841 ttcttgaaaa tgacctcagg aaagcagaag ataaaggttc cagatgatat ttgtaaggag
     3901 gctatctctg tataataagg aaatggcata gacttattcc taatctcatt atgaaacgat
     3961 ggtgtcatgg acgtttaacc atattgcctt tcagcatgct ttgattttac agagacgaca
     4021 ggctttggaa tttactagga agctggctaa aatccatacc cctaggccct acaccagacc
     4081 tttactgaaa cataatagtt gtagtgccca ggaatctaca tttttaacca gccttcctgc
     4141 gtgattctaa tctatgccaa aatttaagaa cattattcaa actctaattt gataaaccaa
     4201 ttgactctaa tagcaggaac cttgttctga ttctcttgtt cataattaag tgtatatata
     4261 ctggtaaaat taatttattc cacagtcaac cttctcttct cattgggaca ttttgttccc
     4321 attttccaag taacttctct ttctacaaaa attgatccaa tattgaagaa ccatctgcga
     4381 ttcatttggg taaaattatg ccttcttcag ttttctgtat cattccctat aagatgccca
     4441 tttgctttga atgtggtatc tttcttttct ttctttcttt tttttttttt ttttgagaca
     4501 gagttttgtt cttcttgttg cccaggctat agtgcaatgg caagatctcg gctcattgca
     4561 acctccacct cccgggttca agcgattctc ctgcctcagc ctcctgagga gctgagttta
     4621 caggcatgtg ccaccaagca tggctaattt tctattttta gtagagacaa ggtttttccc
     4681 tgttggtcag gctggtctcg aactcctgac cttaggtgat cctcccacct cggcctccca
     4741 aagtgctggg attacaggcg tgagccaccg tgcccggcct gaatgtagta tctttcttct
     4801 gttttctttt cctgctcttt aaaaaacaac cttcaacctc tgattattta ttccaacaac
     4861 agctcttcag tagggtaaaa gtcttaacag ttcttcaaac gaacaatatt cttttgtatt
     4921 tttcttcaga gatagcaaat gttataaatg gcctactctg atttaaaaac ctaagttccg
     4981 atgatgatga aacattaact cttaaatata cattttgatt tatagcaata ataacaattg
     5041 taacaacagc aattaagaac agcatctggt gaattcttgg caatgtttcc tggtctcaaa
     5101 acagtaagaa caatttgaag tctgttcttt agaatgccct actcagctgc ataatgttta
     5161 gaaaattaaa gagtctgtat tttaaatatt tttaggtaat tattgcggga cattgtctta
     5221 tggtgtcctg atgtacgtgg ggtgtgcatg tgtgtgtgtg tgtgtgtgca tgtgtctttg
     5281 tgtgtgtgag aaggacagag agaaatgtat gtttcactga aacatttgaa acgaccaatt
     5341 tcactttatt gtgcctgtaa aatgttagtt ttaaaataaa taaaaataat atgaaaataa
//
