LOCUS       XM_024447378            2492 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens serine palmitoyltransferase long chain base
            subunit 1 (SPTLC1), transcript variant X3, mRNA.
ACCESSION   XM_024447378
VERSION     XM_024447378.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024447378.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..2492
                     /gene="SPTLC1"
                     /gene_synonym="ALS27; HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI"
                     /note="serine palmitoyltransferase long chain base subunit
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 43 ESTs, 934 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 101 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10558"
                     /db_xref="HGNC:HGNC:11277"
                     /db_xref="MIM:605712"
     CDS             218..1174
                     /gene="SPTLC1"
                     /gene_synonym="ALS27; HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI"
                     /codon_start=1
                     /product="serine palmitoyltransferase 1 isoform X3"
                     /protein_id="XP_024303146.1"
                     /db_xref="GeneID:10558"
                     /db_xref="HGNC:HGNC:11277"
                     /db_xref="MIM:605712"
                     /translation="MKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGL
                     QASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPL
                     PELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIG
                     GFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQI
                     HKALQGISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARY
                     LEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQAVLL"
ORIGIN      
        1 ccttaggttg agagtttctt cgttgcacaa aggagcatca agagaaacaa gttcttcagt
       61 tacccatatt tacctgtcac aaaacctgct ttgcaaggct gacatcagct aaaacccagt
      121 gtcttctgat agaaggaaaa gactagtctt tttgaacttt tgggactatg ctagaaccaa
      181 tgttcatttg gatttggaag accgcctggc aaaatttatg aagacagaag aagccattat
      241 atactcatat ggatttgcca ccatagccag tgctattcct gcttactcta aaagagggga
      301 cattgttttt gtagatagag ctgcctgctt tgctattcag aaaggattac aggcatcccg
      361 tagtgacatt aagttattta agcataatga catggctgac ctcgagcgac tactaaaaga
      421 acaagagatc gaagatcaaa agaatcctcg caaggctcgt gtaactcggc gtttcattgt
      481 agtagaagga ttgtatatga atactggaac tatttgtcct cttccagaat tggttaagtt
      541 aaaatacaaa tacaaagcaa gaatcttcct ggaggaaagc ctttcatttg gagtcctagg
      601 agagcatggc cgaggagtca ctgaacacta tggaatcaat attgatgata ttgatcttat
      661 cagtgccaac atggagaatg cacttgcttc tattggaggt ttctgctgtg gcaggtcttt
      721 tgtaattgac catcagcgac tttccggcca gggatactgc ttttcagctt cgttacctcc
      781 cctgttagct gctgcagcaa ttgaggccct caacatcatg gaagagaatc caggtatttt
      841 tgcagtgttg aaggaaaagt gcggacaaat tcataaagct ttacaaggca tttctggatt
      901 aaaagtggtg ggggagtccc tttctccagc ctttcaccta caactggaag agagcactgg
      961 gtctcgcgag caagatgtca gactgcttca ggaaattgta gatcaatgca tgaacagaag
     1021 tattgcatta actcaggcgc gctacttgga gaaagaagag aagtgtctcc ctcctcccag
     1081 cattcgggtt gtggtcacgg tggaacaaac agaggaagaa ctggagagag ctgcgtccac
     1141 catcaaggag gtagcccagg ccgtcctgct ctaggcagag tcccgggacc atggcctcct
     1201 gccacacaac acgcagagag gactcaagac tcccgctggc catggagtgg cctgaaagag
     1261 agcaagaaca tgtggatctt tgataggatt gttaccaaat ggtgtcagta tggaccaatt
     1321 gtgtgaccat gagaaggatg cttatttttt ttaaaaagaa aacacatcta aaagcccagg
     1381 aactgatttt tttaagagga aaactaatga cagtgtataa ctgatgttta aattgtgcat
     1441 ttagtactat ttaaatgttt tcttatacta gtattttata ttcttttgtt gtcgtttaaa
     1501 actggagctt cagtgtctct tccctccctc taatagtaat ggttcagtaa gcactcctta
     1561 actccttagt atttcataga aaaatgactg caacattaaa gctaagagga acacttcaac
     1621 atatgtggta caaatttata ttgaagatct aaataaacca cgtattttcc agtcttcgtt
     1681 gtgtgaagct aaatggtggc taaaaggaac actttttgtg tgattattat aaactttgca
     1741 ttgtatttga atcttagaac ttttgtacac actaaatatt gatgtcacac catttctaat
     1801 ctgagcatcc ttagccagag aatattcatt atacttccta agtgagcaat aatttaaatc
     1861 agaagctatt ttattttaat gtaattaacc tttctttaca tttcttatgt gttcacctct
     1921 aatctgtttt aggaagagag ttggttatta tgttgatccc ataatataaa tcatatcctt
     1981 tatattttag aatatctcaa atgtattcct tttttgtatg gtgggtttgc ctagggacgt
     2041 gtaactacag gcttttacta agccaaggaa aaagagaatt tttcttttca tcttacaaat
     2101 tccagatatc tacaaaagat gtgaaagcac taaaaatacc atttttaagc agtactttac
     2161 ctgttttttc tttagcaaac caggttatgt ggtgtaaagg tttgttatac gtgccacaat
     2221 atagcatata aatattatgc catcattcct tctcttgtta aaggtagaag aataaaattg
     2281 tgatttttat aacctgtgct tattactcaa atggtcttca acatcttttt aaacaacaca
     2341 tactttttga atgttcagtt tctattttgc ttgaggtatt ttgtacatat gtgccttgtg
     2401 attgctgctg ctttaaagga taaagtactc tttgggggat gagtctggtt tgttttgttt
     2461 tattttttaa tgaaataaac ctatattcct ga
//
