LOCUS       NM_152670                798 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens sperm microtubule inner protein 9 (SPMIP9), mRNA.
ACCESSION   NM_152670
VERSION     NM_152670.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Leung,M.R., Zeng,J., Wang,X., Roelofs,M.C., Huang,W., Zenezini
            Chiozzi,R., Hevler,J.F., Heck,A.J.R., Dutcher,S.K., Brown,A.,
            Zhang,R. and Zeev-Ben-Mordehai,T.
  TITLE     Structural specializations of the sperm tail
  JOURNAL   Cell 186 (13), 2880-2896 (2023)
   PUBMED   37327785
REFERENCE   2  (bases 1 to 798)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 798)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 798)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 798)
  AUTHORS   Jumeau,F., Com,E., Lane,L., Duek,P., Lagarrigue,M., Lavigne,R.,
            Guillot,L., Rondel,K., Gateau,A., Melaine,N., Guevel,B.,
            Sergeant,N., Mitchell,V. and Pineau,C.
  TITLE     Human Spermatozoa as a Model for Detecting Missing Proteins in the
            Context of the Chromosome-Centric Human Proteome Project
  JOURNAL   J Proteome Res 14 (9), 3606-3620 (2015)
   PUBMED   26168773
REFERENCE   6  (bases 1 to 798)
  AUTHORS   Yu,Z., Tang,A., Gui,Y., Guo,X., Zhu,H., Long,Y., Li,Z. and Cai,Z.
  TITLE     Identification and characteristics of a novel testis-specific gene,
            Tsc21, in mice and human
  JOURNAL   Mol Biol Rep 34 (2), 127-134 (2007)
   PUBMED   17091336
  REMARK    GeneRIF: Identification of a novel gene, Tsc21, exclusively
            expressed in testes.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104134.4, AK058098.1 and AW104588.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152670.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.381369.1,
                                           SRR5189667.143914.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000303254.4/ ENSP00000307142.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC104134.4         34636-34637
            3-733               AK058098.1         1-731
            734-798             AW104588.1         3-67                c
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p11.2"
     gene            1..798
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /note="sperm microtubule inner protein 9"
                     /db_xref="GeneID:200523"
                     /db_xref="HGNC:HGNC:26341"
                     /db_xref="MIM:619676"
     exon            1..134
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /inference="alignment:Splign:2.1.0"
     exon            135..171
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..687
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /note="protein TSC21; testis-specific conserved protein of
                     21 kDa; testis-expressed sequence 37 protein;
                     Testis-Specific Conserved gene 21kDa; testis tissue
                     sperm-binding protein Li 93mP; testis expressed 37"
                     /codon_start=1
                     /product="protein SPMIP9"
                     /protein_id="NP_689883.1"
                     /db_xref="CCDS:CCDS2003.1"
                     /db_xref="GeneID:200523"
                     /db_xref="HGNC:HGNC:26341"
                     /db_xref="MIM:619676"
                     /translation="MAGVKYPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKL
                     DAQLRDKEFYRPIPNPNPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEATREDERKF
                     TSTCHFTYPASHDLHLAQGDPNQVLQSADFPCLVDPKHQPAAEMAKGYLLLPGCPCLH
                     CHIVKVPILNRWGPLMPFYQ"
     exon            172..264
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /inference="alignment:Splign:2.1.0"
     exon            265..798
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      770..775
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /note="hexamer: AATAAA"
     polyA_site      798
                     /gene="SPMIP9"
                     /gene_synonym="C2orf51; TEX37; TSC21"
                     /note="major polyA site"
ORIGIN      
        1 acagcaacag gactctccat gtggcaaggg cacctggagg tgggagggca ggagcgtcgt
       61 cttgccctgg cagaagaagc ggtaggctct gtctgcgtgg cagctggtcc ccagccctag
      121 gagagaagct gtctgtcgtt tgccatggca ggtgtgaaat acccgggaca ggaccctgtg
      181 gatttagaca tataccaaag ctcccacatg gtcgactatc agccctacag gaagcacaaa
      241 tactccaggg tcacgccgca agagcaggca aagctcgatg ctcaactccg ggacaaagag
      301 ttttacaggc ccatccctaa ccccaacccc aagctaacag atgggtaccc tgctttcaaa
      361 agaccccaca tgactgccaa agacctggga ctccccggct tcttcccatc acaggaacat
      421 gaggccacga gggaggacga gcgcaagttc accagcacct gccatttcac atatccagct
      481 tcccacgatc tgcacctggc ccagggtgac cccaaccagg tcctccagag tgctgacttt
      541 ccgtgcctcg tggatcccaa acaccagcct gctgcagaga tggccaaagg ctacctgcta
      601 ctgccagggt gtccctgtct tcattgccat atagtcaagg tccccatctt gaaccggtgg
      661 ggacccttga tgccatttta ccagtaggaa ggatgaaaat accttccaaa ggctcttcca
      721 agggcatgtg gaaatcctat gaccttggag tgcagagagg agaactgaaa ataaaactgg
      781 aaagatgttc caactgca
//
