LOCUS       NM_001161834            1607 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens sperm microtubule inner protein 7 (SPMIP7), mRNA.
ACCESSION   NM_001161834 XM_001713888 XM_001714376 XM_001714936 XM_002344308
VERSION     NM_001161834.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Leung,M.R., Zeng,J., Wang,X., Roelofs,M.C., Huang,W., Zenezini
            Chiozzi,R., Hevler,J.F., Heck,A.J.R., Dutcher,S.K., Brown,A.,
            Zhang,R. and Zeev-Ben-Mordehai,T.
  TITLE     Structural specializations of the sperm tail
  JOURNAL   Cell 186 (13), 2880-2896 (2023)
   PUBMED   37327785
REFERENCE   2  (bases 1 to 1607)
  AUTHORS   Zhang,J., Yan,R., Wu,C., Wang,H., Yang,G., Zhong,Y., Liu,Y., Wan,L.
            and Tang,A.
  TITLE     Spermatogenesis-associated 48 is essential for spermatogenesis in
            mice
  JOURNAL   Andrologia 50 (6), e13027 (2018)
   PUBMED   29700843
  REMARK    GeneRIF: In humans and mice with azoospermia, expression of SPATA48
            disappeared in the testis.
REFERENCE   3  (bases 1 to 1607)
  AUTHORS   L'Hote,D., Vatin,M., Auer,J., Castille,J., Passet,B.,
            Montagutelli,X., Serres,C. and Vaiman,D.
  TITLE     Fidgetin-like1 is a strong candidate for a dynamic impairment of
            male meiosis leading to reduced testis weight in mice
  JOURNAL   PLoS One 6 (11), e27582 (2011)
   PUBMED   22110678
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC034148.9 and AC020743.7.
            
            On Jul 25, 2019 this sequence version replaced NM_001161834.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.133274.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000297001.7/ ENSP00000297001.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-756               AC034148.9         148795-149550
            757-854             AC034148.9         157226-157323
            855-931             AC020743.7         11901-11977
            932-1070            AC020743.7         16292-16430
            1071-1138           AC020743.7         18282-18349
            1139-1180           AC020743.7         22324-22365
            1181-1288           AC020743.7         23465-23572
            1289-1396           AC020743.7         33634-33741
            1397-1607           AC020743.7         41230-41440
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p12.2"
     gene            1..1607
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /note="sperm microtubule inner protein 7"
                     /db_xref="GeneID:100130988"
                     /db_xref="HGNC:HGNC:22564"
     exon            1..756
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1520
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /note="uncharacterized protein C7orf72;
                     spermatogenesis-associated protein 48; spermatogenesis
                     associated 48"
                     /codon_start=1
                     /product="protein SPMIP7"
                     /protein_id="NP_001155306.3"
                     /db_xref="CCDS:CCDS47585.1"
                     /db_xref="GeneID:100130988"
                     /db_xref="HGNC:HGNC:22564"
                     /translation="MDVEIQDTPGKISISKRSILSGTVENIDYPHYCDLLRKMNMPFV
                     KGLENRHNYGRFEKKCNPAFLKFHPYPPSVLPDYHLHDPYPPPYGPHYPLFPLRDDVT
                     LGDSCSGFMSPGGDADLNPGIGRTIPTLVDFSDVKPQHRVPRPDTGFQTTIKRQKILS
                     EELQQNRRWNSREVPDISIRARLGGWTSPLKVTPLQPHHEGRSLSHIFTFDEEATCTD
                     EGEPLVQTNKKCNAKDSFYKSSTQKAYEDVPWDKMLPPKLVPEETTLEKTADPISQCF
                     TLKRYKGVPAITQMVGELWDRFQTRSFLAPVKPINFVSSSSRSKYIPLYTGHVQSTNA
                     DDVDNPLGDIASLAKQRYSKPLYTNTSRAANIPGYTGKVHFTATHPANSNIPSTTPSP
                     DSELHRVFQKEMAVDLFRHQAPLSRLVTTVRPYNPFNKKDKETIDY"
     exon            757..854
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            855..931
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1070
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1138
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1180
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1288
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1396
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1607
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1584..1589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /note="hexamer: AATAAA"
     polyA_site      1607
                     /gene="SPMIP7"
                     /gene_synonym="C7orf72; SPATA48"
                     /note="major polyA site"
ORIGIN      
        1 attgccctat tcttcctttg gtggaggaaa atatttgcct taaaaagaaa aacaaaatta
       61 tctgccaaca tttagaaagc tgtgtcaatt ttatactagt ttaacacaga tctttagtta
      121 ttggcaatag agtttatata gttaaatata aaggaattat cagaaatact ttatagttat
      181 caaaaattct aaagaaaaag gccatggatg tagaaattca ggacacacct ggaaagataa
      241 gtatctctaa aaggtccatc ctttcaggaa ctgttgagaa tatagattac ccacactatt
      301 gtgatctctt aagaaaaatg aacatgcctt ttgtgaaagg tcttgagaac agacataact
      361 atggcaggtt tgaaaagaaa tgcaaccctg cttttcttaa atttcaccct tatccccctt
      421 cagttttgcc agactatcat ttacatgatc cttatccccc accatatggg ccacattatc
      481 cattatttcc acttcgggat gatgtgacct taggtgattc ctgttcaggg tttatgagtc
      541 ctggtggtga tgctgattta aatcctggca ttggcagaac cataccaacc ctagtggatt
      601 ttagtgatgt gaaacctcaa catcgagttc ccagaccaga cacaggattt caaacaacaa
      661 taaaaaggca aaaaattcta tcagaagaac tgcaacagaa caggagatgg aattccaggg
      721 aagtaccaga catttctatc agagcaagac ttggaggttg gacaagccct ctgaaagtta
      781 ctcccttaca acctcatcat gaaggacgct cattaagtca catatttaca tttgatgagg
      841 aggcaacatg tacagatgaa ggtgaaccac ttgttcaaac aaacaagaaa tgtaatgcaa
      901 aggactcatt ttacaagtcc tctacacaaa aagcttatga agatgttcct tgggataaga
      961 tgctaccacc aaaacttgtt ccagaagaaa caacattgga aaaaaccgct gaccccatct
     1021 cacagtgttt tactctgaaa agatataaag gggtgccagc aataactcag atggttggtg
     1081 agctctggga cagatttcaa acaagatctt tcttggcacc agtcaaacca attaattttg
     1141 tgagttcaag ttctagaagt aaatatattc ctctctatac tggtcatgtg cagtctacaa
     1201 atgctgatga tgttgacaac cccttgggag acatcgcatc gctagccaag cagcggtact
     1261 ctaagcctct ttatacaaac acaagtcgtg ctgcaaatat tccaggatat accggcaagg
     1321 ttcatttcac agccacccac ccagcaaatt ctaatattcc atcaacaacc ccatcaccag
     1381 attcagaact gcaccgcgtc ttccagaaag aaatggcagt tgacctcttc cgtcaccagg
     1441 ctcccctgtc tcgactggtc acaactgtga gaccctacaa ccctttcaac aagaaggaca
     1501 aagaaaccat agactactag aggaggcggc cctgcgcggg ctgtccaggc ctccgcctgg
     1561 ggaaggcttg tgcggcggtg ggaaataaag gctgcttctc cgcgctg
//
