LOCUS       NM_001286811             902 bp    mRNA    linear   PRI 16-JUL-2024
DEFINITION  Homo sapiens SPEG neighbor (SPEGNB), transcript variant 1, coding,
            mRNA.
ACCESSION   NM_001286811 XM_003846224 XM_003846661 XM_003960304
VERSION     NM_001286811.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC053503.7.
            
            On Oct 29, 2020 this sequence version replaced NM_001286811.1.
            
            Transcript Variant: This transcript represents the coding allele.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR4368410.79247.1,
                                           DRR138525.441475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465413 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000651166.2/ ENSP00000498687.1
            polymorphic pseudogene :: based on alignments, homology
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                AC053503.7         153935-154021
            88-215              AC053503.7         154159-154286
            216-523             AC053503.7         154613-154920
            524-665             AC053503.7         155524-155665
            666-902             AC053503.7         155855-156091
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q35"
     gene            1..902
                     /gene="SPEGNB"
                     /note="SPEG neighbor"
                     /db_xref="GeneID:100996693"
                     /db_xref="HGNC:HGNC:51251"
     exon            1..87
                     /gene="SPEGNB"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..804
                     /gene="SPEGNB"
                     /codon_start=1
                     /product="SPEG neighbor protein"
                     /protein_id="NP_001273740.1"
                     /db_xref="GeneID:100996693"
                     /db_xref="HGNC:HGNC:51251"
                     /translation="MSKAAPAKKPVAVAPAPGCTLDINDPQVQSAAIRIQASYRGHRS
                     RKELREKGPPRVLEPLKDVVLIEGSAAKLTCRISAFPDPFIRWSKDGKELRDGPKYRY
                     VFEDPDVVALVVRDGELADLGQYSINVTNPFGQCSDSARILVEVPTKIQKGPDNTKAR
                     KGTTVTLTAEILGEPAPDVGWTKDGEDIEEDDRVFFEIGSTTTTLTIRRATPQDSGKY
                     EVYVENSLGMDQSFARVDVA"
     exon            88..215
                     /gene="SPEGNB"
                     /inference="alignment:Splign:2.1.0"
     exon            216..523
                     /gene="SPEGNB"
                     /inference="alignment:Splign:2.1.0"
     exon            524..665
                     /gene="SPEGNB"
                     /inference="alignment:Splign:2.1.0"
     exon            666..902
                     /gene="SPEGNB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      880..885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPEGNB"
                     /note="hexamer: AATAAA"
     polyA_site      902
                     /gene="SPEGNB"
                     /note="major polyA site"
ORIGIN      
        1 ctgcacccct actgtgccat ccagaagggc tctgtgctgc ctgcaatcca gccagtcgac
       61 tcaagtccct aggtcaaccc ctccacgatg tctaaagcag ctcctgccaa aaagccagtg
      121 gctgtggccc cagctcctgg atgtaccctg gacatcaatg acccacaggt ccagagtgcg
      181 gccattcgta tccaggcctc ttaccggggc cacaggtccc ggaaggagct gcgcgagaag
      241 gggccgccgc gggtgctgga gccgctgaag gacgtggtgc tgatcgaagg cagcgcggcc
      301 aagctcactt gccgcatttc ggctttcccg gacccattca tccgctggag taaggacggc
      361 aaggagctac gtgacggtcc caagtaccgc tacgtcttcg aggaccctga cgtggtggca
      421 ctggtggtgc gcgacggcga gctggcagac ctgggccagt acagcatcaa cgtcaccaac
      481 cccttcggcc agtgctccga ctcggcgcgc atcctcgtgg aagtcccgac gaagattcaa
      541 aagggacccg acaacactaa ggcgcgcaaa ggcaccaccg tgacgctgac tgcggagatc
      601 ctgggagagc ctgcgcccga cgtaggctgg accaaggacg gggaggacat cgaggaggat
      661 gacagggtgt tcttcgagat cggcagcacc accacgacgc tgaccattcg ccgggccacg
      721 cctcaggaca gcggcaagta cgaggtgtac gtggagaaca gcctgggcat ggaccagagc
      781 ttcgctcgcg tcgacgtggc ctgaacggca cccccggacc ttccgccctg gcgccgagcc
      841 cgggggtggt gggacccaca gccctccacc agcttgctta ataaagctgc tctctgaccc
      901 tc
//
