LOCUS       XM_005246240            8392 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens striated muscle enriched protein kinase
            (SPEG), transcript variant X16, mRNA.
ACCESSION   XM_005246240
VERSION     XM_005246240.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 3, 2014 this sequence version replaced XM_005246240.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8392
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..8392
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /note="striated muscle enriched protein kinase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 14 ESTs, 101 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 32 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10290"
                     /db_xref="HGNC:HGNC:16901"
                     /db_xref="MIM:615950"
     CDS             293..7549
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /codon_start=1
                     /product="striated muscle preferentially expressed protein
                     kinase isoform X14"
                     /protein_id="XP_005246297.1"
                     /db_xref="GeneID:10290"
                     /db_xref="HGNC:HGNC:16901"
                     /db_xref="MIM:615950"
                     /translation="MKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQ
                     GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGAR
                     QCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQ
                     PALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFT
                     RLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAH
                     VGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELE
                     RLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD
                     VHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMV
                     TLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIF
                     RVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNH
                     VEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQ
                     TCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHV
                     SFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGED
                     EDHRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREAR
                     LLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLE
                     GIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEF
                     VAPEIVNQSPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTF
                     LSLSREARGFLIKVLVQDRLRPTAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQR
                     SQISYKCHLVLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPR
                     PLQPEFSGSRVSLTDIPTEDEALGTPETGAATPMDWQEQGRAPSQDQEAPSPEALPSP
                     GQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRSPSPGATRL
                     ARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSE
                     AAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSA
                     LSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASK
                     PAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASP
                     PPGAPEKRVPSAGGPPVLAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRES
                     PLSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVG
                     EPGLVRRLSLSLSQRLRRTPPAQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSF
                     TLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGA
                     TTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQY
                     VRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIV
                     SCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQ
                     DTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVA
                     CANRAGQGPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSRPARARPPDSPTSLAPPL
                     APAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPST
                     HVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPE
                     PTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRFGVVR
                     ACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIA
                     ESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDN
                     ALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIML
                     SGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCL
                     AHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGGP"
ORIGIN      
        1 cttctccgtg cagggcctca gctgggtcag ccgagtgagt ggggctgggc aggctggaca
       61 ggctgggctc ctgctccctg gggagccacg ctggggtggg cagtgggcag gcagcaggag
      121 ggcctggtgc cagggcagag ccttcaggac aggcacaggc tggggtctgt gtgcagagcc
      181 tcggggtggg tctacatccc ctttcagcag ccccatcacc tccgacgagg aatacctgag
      241 ccccccagag gagttcccag agcctgggga gacctggccg cgaaccccca ccatgaagcc
      301 cagtcccagc cagaaccgcc gttcttctga cactggctcc aaggcacccc ccaccttcaa
      361 ggtctcactt atggaccagt cagtaagaga aggccaagat gtcatcatga gcatccgcgt
      421 gcagggggag cccaagcctg tggtctcctg gctgagaaac cgccagcccg tgcgcccaga
      481 ccagcggcgc tttgcggagg aggctgaggg tgggctgtgc cggctgcgga tcctggctgc
      541 agagcgtggc gatgctggtt tctacacttg caaagcggtc aatgagtatg gtgctcggca
      601 gtgcgaggcc cgcttggagg tccgagcaca ccctgaaagc cggtccctgg ccgtgctggc
      661 ccccctgcag gacgtggacg tgggggccgg ggagatggcg ctgtttgagt gcctggtggc
      721 ggggcccact gacgtggagg tggattggct gtgccgtggc cgcctgctgc agcctgcact
      781 gctcaaatgc aagatgcatt tcgatggccg caaatgcaag ctgctactta catctgtaca
      841 tgaggacgac agtggcgtct acacctgcaa gctcagcacg gccaaagatg agctgacctg
      901 cagtgcccgg ctgaccgtgc ggccctcgtt ggcacccctg ttcacacggc tgctggaaga
      961 tgtggaggtg ttggagggcc gagctgcccg tttcgactgc aagatcagtg gcaccccgcc
     1021 ccctgttgtt acctggactc attttggctg ccccatggag gagagtgaga acttgcggct
     1081 gcggcaggac gggggtctgc actcactgca cattgcccat gtgggcagcg aggacgaggg
     1141 gctctatgcg gtcagtgctg ttaacaccca tggccaggcc cactgctcag cccagctgta
     1201 tgtagaagag ccccggacag ccgcctcagg ccccagctcg aagctggaga agatgccatc
     1261 cattcccgag gagccagagc agggtgagct ggagcggctg tccattcctg acttcctgcg
     1321 gccactgcag gacctggagg tgggactggc caaggaggcc atgctagagt gccaggtgac
     1381 cggcctgccc taccccacca tcagctggtt ccacaatggc caccgcatcc agagcagcga
     1441 cgaccggcgc atgacacagt acagggatgt ccatcgcttg gtgttccctg ccgtggggcc
     1501 tcagcacgcc ggtgtctaca agagcgtcat tgccaacaag ctgggcaaag ctgcctgcta
     1561 tgcccacctg tatgtcacag atgtggtccc aggccctcca gatggcgccc cgcaggtggt
     1621 ggctgtgacg gggaggatgg tcacactcac atggaacccc cccaggagtc tggacatggc
     1681 catcgacccg gactccctga cgtacacagt gcagcaccag gtgctgggct cggaccagtg
     1741 gacggcactg gtcacaggcc tgcgggagcc agggtgggca gccacagggc tgcgtaaggg
     1801 ggtccagcac atcttccggg tcctcagcac cactgtcaag agcagcagca agccctcacc
     1861 cccttctgag cctgtgcagc tgctggagca cggcccaacc ctggaggagg cccctgccat
     1921 gctggacaaa ccagacatcg tgtatgtggt ggagggacag cctgccagcg tcaccgtcac
     1981 attcaaccat gtggaggccc aggtcgtctg gaggagctgc cgaggggccc tcctagaggc
     2041 acgggccggt gtgtacgagc tgagccagcc agatgatgac cagtactgtc ttcggatctg
     2101 ccgggtgagc cgccgggaca tgggggccct cacctgcacc gcccgaaacc gtcacggcac
     2161 acagacctgc tcggtcacat tggagctggc agaggcccct cggtttgagt ccatcatgga
     2221 ggacgtggag gtgggggctg gggaaactgc tcgctttgcg gtggtggtcg agggaaaacc
     2281 actgccggac atcatgtggt acaaggacga ggtgctgctg accgagagca gccatgtgag
     2341 cttcgtgtac gaggagaatg agtgctccct ggtggtgctc agcacggggg cccaggatgg
     2401 aggcgtctac acctgcaccg cccagaacct ggcgggtgag gtctcctgca aagcagagtt
     2461 ggctgtgcat tcagctcaga cagctatgga ggtcgagggg gtcggggagg atgaggacca
     2521 tcgaggaagg agactcagcg acttttatga catccaccag gagatcggca ggggtgcttt
     2581 ctcctacttg cggcgcatag tggagcgtag ctccggcctg gagtttgcgg ccaagttcat
     2641 ccccagccag gccaagccaa aggcatcagc gcgtcgggag gcccggctgc tggccaggct
     2701 ccagcacgac tgtgtcctct acttccatga ggccttcgag aggcgccggg gactggtcat
     2761 tgtcaccgag ctctgcacag aggagctgct ggagcgaatc gccaggaaac ccaccgtgtg
     2821 tgagtctgag atccgggcct atatgcggca ggtgctagag ggaatacact acctgcacca
     2881 gagccacgtg ctgcacctcg atgtcaagcc tgagaacctg ctggtgtggg atggtgctgc
     2941 gggcgagcag caggtgcgga tctgtgactt tgggaatgcc caggagctga ctccaggaga
     3001 gccccagtac tgccagtatg gcacacctga gtttgtagca cccgagattg tcaatcagag
     3061 ccccgtgtct ggagtcactg acatctggcc tgtgggtgtt gttgccttcc tctgtctgac
     3121 aggaatctcc ccgtttgttg gggaaaatga ccggacaaca ttgatgaaca tccgaaacta
     3181 caacgtggcc ttcgaggaga ccacattcct gagcctgagc agggaggccc ggggcttcct
     3241 catcaaagtg ttggtgcagg accggctgag acctaccgca gaagagaccc tagaacatcc
     3301 ttggttcaaa actcaggcaa agggcgcaga ggtgagcacg gatcacctga agctattcct
     3361 ctcccggcgg aggtggcagc gctcccagat cagctacaaa tgccacctgg tgctgcgccc
     3421 catccccgag ctgctgcggg cccccccaga gcgggtgtgg gtgaccatgc ccagaaggcc
     3481 accccccagt ggggggctct catcctcctc ggattctgaa gaggaagagc tggaagagct
     3541 gccctcagtg ccccgcccac tgcagcccga gttctctggc tcccgggtgt ccctcacaga
     3601 cattcccact gaggatgagg ccctggggac cccagagact ggggctgcca cccccatgga
     3661 ctggcaggag cagggaaggg ctccctctca ggaccaggag gctcccagcc cagaggccct
     3721 cccctcccca ggccaggagc ccgcagctgg ggctagcccc aggcggggag agctccgcag
     3781 gggcagctcg gctgagagcg ccctgccccg ggccgggccg cgggagctgg gccggggcct
     3841 gcacaaggcg gcgtctgtgg agctgccgca gcgccggagc cccagcccgg gagccacccg
     3901 cctggcccgg ggaggcctgg gtgagggcga gtatgcccag aggctgcagg ccctgcgcca
     3961 gcggctgctg cggggaggcc ccgaggatgg caaggtcagc ggcctcaggg gtcccctgct
     4021 ggagagcctg gggggccgtg ctcgggaccc ccggatggca cgagctgcct ccagcgaggc
     4081 agcgccccac caccagcccc cactcgagaa ccggggcctg caaaagagca gcagcttctc
     4141 ccagggtgag gcggagcccc ggggccggca ccgccgagcg ggggcgcccc tcgagatccc
     4201 cgtggccagg cttggggccc gtaggctaca ggagtctcct tccctgtctg ccctcagcga
     4261 ggcccagcca tccagccctg cacggcccag cgcccccaaa cccagtaccc ctaagtctgc
     4321 agaaccttct gccaccacac ctagtgatgc tccgcagccc cccgcacccc agcctgccca
     4381 agacaaggct ccagagccca ggccagaacc agtccgagcc tccaagcctg caccaccccc
     4441 ccaggccctg caaaccctag cgctgcccct cacaccctat gctcagatca ttcagtccct
     4501 ccagctgtca ggccacgccc agggcccctc gcagggccct gccgcgccgc cttcagagcc
     4561 caagccccac gctgctgtct ttgccagggt ggcctcccca cctccgggag cccccgagaa
     4621 gcgcgtgccc tcagccgggg gtcccccggt gctagccgag aaagcccgag ttcccacggt
     4681 gccccccagg ccaggcagca gtctcagtag cagcatcgaa aacttggagt cggaggccgt
     4741 gttcgaggcc aagttcaagc gcagccgcga gtcgcccctg tcgctggggc tgcggctgct
     4801 gagccgttcg cgctcggagg agcgcggccc cttccgtggg gccgaggagg aggatggcat
     4861 ataccggccc agcccggcgg ggaccccgct ggagctggtg cgacggcctg agcgctcacg
     4921 ctcggtgcag gacctcaggg ctgtcggaga gcctggcctc gtccgccgcc tctcgctgtc
     4981 actgtcccag cggctgcggc ggacccctcc cgcgcagcgc cacccggcct gggaggcccg
     5041 cggcggggac ggagagagct cggagggcgg gagctcggcg cggggctccc cggtgctggc
     5101 gatgcgcagg cggctgagct tcaccctgga gcggctgtcc agccgattgc agcgcagtgg
     5161 cagcagcgag gactcggggg gcgcgtcggg ccgcagcacg ccgctgttcg gacggcttcg
     5221 cagggccacg tccgagggcg agagtctgcg gcgccttggc cttccgcaca accagttggc
     5281 cgcccaggcc ggcgccacca cgccttccgc cgagtccctg ggctccgagg ccagcgccac
     5341 gtcgggctcc tcagccccag gggaaagccg aagccggctc cgctggggct tctctcggcc
     5401 gcggaaggac aaggggttat cgccaccaaa cctctctgcc agcgtccagg aggagttggg
     5461 tcaccagtac gtgcgcagtg agtcagactt ccccccagtc ttccacatca aactcaagga
     5521 ccaggtgctg ctggaggggg aggcagccac cctgctctgc ctgccagcgg cctgccctgc
     5581 accgcacatc tcctggatga aagacaagaa gtccttgagg tcagagccct cagtgatcat
     5641 cgtgtcctgc aaagatgggc ggcagctgct cagcatcccc cgggcgggca agcggcacgc
     5701 cggtctctat gagtgctcgg ccaccaacgt actgggcagc atcaccagct cctgtaccgt
     5761 ggctgtggcc cgagtcccag gaaagctagc tcctccagag gtaccccaga cctaccagga
     5821 cacggcgctg gtgctgtgga agccgggaga cagccgggca ccttgcacgt atacgctgga
     5881 gcggcgagtg gatggggagt ctgtgtggca ccctgtgagc tcaggcatcc ccgactgtta
     5941 ctacaacgtg acccacctgc cagttggcgt gactgtgagg ttccgtgtgg cctgtgccaa
     6001 ccgtgctggg caggggccct tcagcaactc ttctgagaag gtctttgtca ggggtactca
     6061 agattcttca gctgtgccat ctgctgccca ccaagaggcc cctgtcacct caaggccagc
     6121 cagggcccgg cctcctgact ctcctacctc actggcccca cccctagctc ctgctgcccc
     6181 cacacccccg tcagtcactg tcagcccctc atctcccccc acacctccta gccaggcctt
     6241 gtcctcgctc aaggctgtgg gtccaccacc ccaaacccct ccacgaagac acaggggcct
     6301 gcaggctgcc cggccagcgg agcccaccct acccagtacc cacgtcaccc caagtgagcc
     6361 caagcctttc gtccttgaca ctgggacccc gatcccagcc tccactcctc aaggggttaa
     6421 accagtgtct tcctctactc ctgtgtatgt ggtgacttcc tttgtgtctg caccaccagc
     6481 ccctgagccc ccagcccctg agccccctcc tgagcctacc aaggtgactg tgcagagcct
     6541 cagcccggcc aaggaggtgg tcagctcccc tgggagcagt ccccgaagct ctcccaggcc
     6601 tgagggtacc actcttcgac agggtccccc tcagaaaccc tacaccttcc tggaggagaa
     6661 agccaggggc cgctttggtg ttgtgcgagc gtgccgggag aatgccacgg ggcgaacgtt
     6721 cgtggccaag atcgtgccct atgctgccga gggcaagcgg cgggtcctgc aggagtacga
     6781 ggtgctgcgg accctgcacc acgagcggat catgtccctg cacgaggcct acatcacccc
     6841 tcggtacctc gtgctcattg ctgagagctg tggcaaccgg gaactcctct gtgggctcag
     6901 tgacaggttc cggtattctg aggatgacgt ggccacttac atggtgcagc tgctacaagg
     6961 cctggactac ctccacggcc accacgtgct ccacctagac atcaagccag acaacctgct
     7021 gctggcccct gacaatgccc tcaagattgt ggactttggc agtgcccagc cctacaaccc
     7081 ccaggccctt aggccccttg gccaccgcac gggcacgctg gagttcatgg ctccggagat
     7141 ggtgaaggga gaacccatcg gctctgccac ggacatctgg ggagcgggtg tgctcactta
     7201 cattatgctc agtggacgct ccccgttcta tgagccagac ccccaggaaa cggaggctcg
     7261 gattgtgggg ggccgctttg atgccttcca gctgtacccc aatacatccc agagcgccac
     7321 cctcttcttg cgaaaggttc tctctgtaca tccctggagc cggccctccc tgcaggactg
     7381 cctggcccac ccatggttgc aggacgccta cctgatgaag ctgcgccgcc agacgctcac
     7441 cttcaccacc aaccggctca aggagttcct gggcgagcag cggcggcgcc gggctgaggc
     7501 tgccacccgc cacaaggtgc tgctgcgctc ctaccctggc ggcccctaga ggcacggacc
     7561 acagccaggc ctcgggcttc aactggggtt cccaccaatg ccacgggaca ttccagggcc
     7621 cacgctgagc caggcgggcc tggggcttcg gttaccacca gcagcaacat ctggctgggc
     7681 tcttacctca tagaccttca aggacagaga ccccagggcc tggacctgat gccaccccag
     7741 gccaaagcca gagtgggaga cccattggtc aggctcagca gggtgggaac aggcagaggg
     7801 acaagagggg aatggagaag tggagaggaa aaggaatcga gggacaggaa gggggaggct
     7861 ctaggaaggt tctgggttgg gggtcagtgc atctcaggga gaaccaagga aggtgggcat
     7921 ggctggagag gaggaaaagg aaggagcccc aggtgtcagg gcagtaggct gggagtcagt
     7981 gtggcaaagc gggggcagga cacagataca gtggcagggg cccagggctg ggacatgaga
     8041 gaaggcagcg aggcggcaga gggagaagag aggactcagg tggaggtggg gtgggtcagc
     8101 tgtcagcatc cctcagagga gaaatgtgga gagctggagg ccagcagtca ctcacactcg
     8161 ctctgtcctc ctgtccagtg gatacagccc tgggcgctct gctggcccaa ggatgtcccc
     8221 actgcccctc catggcctct ggccttcttc ccattcatat ttatttattt attgactttt
     8281 atgaagtttc cccttccatc cgatccctac tgcccatgtt gtcctgacca tccctcccag
     8341 ccatccagct gtctgtctgt ctgccacaag gaaataaaaa tggcaagcag ca
//
