LOCUS       NM_005876              10782 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens striated muscle enriched protein kinase (SPEG),
            transcript variant 1, mRNA.
ACCESSION   NM_005876 XM_051005
VERSION     NM_005876.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10782)
  AUTHORS   Gurgel-Giannetti,J., Souza,L.S., Messina de Padua Andrade,G.F.,
            Derlene,M.F., Meira,Z.M.A., Azevedo,B.V.M., Jr,W.C., Diniz,S.S.L.,
            Carvalhais,M.B., Oliveira,J.R.S., Uliana,L., Braulio,R.,
            Costa,P.H.N., Filho,G.B. and Vainzof,M.
  TITLE     A Novel SPEG mutation causing congenital myopathy with fiber size
            disproportion and dilated cardiomyopathy with heart transplantation
  JOURNAL   Neuromuscul Disord 31 (11), 1199-1206 (2021)
   PUBMED   34742623
  REMARK    GeneRIF: A Novel SPEG mutation causing congenital myopathy with
            fiber size disproportion and dilated cardiomyopathy with heart
            transplantation.
REFERENCE   2  (bases 1 to 10782)
  AUTHORS   Almannai,M., Luo,S., Faqeih,E., Almutairi,F., Li,Q. and
            Agrawal,P.B.
  TITLE     Homozygous SPEG Mutation Is Associated With Isolated Dilated
            Cardiomyopathy
  JOURNAL   Circ Genom Precis Med 14 (2), e003310 (2021)
   PUBMED   33794647
  REMARK    GeneRIF: Homozygous SPEG Mutation Is Associated With Isolated
            Dilated Cardiomyopathy.
REFERENCE   3  (bases 1 to 10782)
  AUTHORS   Campbell,H.M., Quick,A.P., Abu-Taha,I., Chiang,D.Y., Kramm,C.F.,
            Word,T.A., Brandenburg,S., Hulsurkar,M., Alsina,K.M., Liu,H.B.,
            Martin,B., Uhlenkamp,D., Moore,O.M., Lahiri,S.K., Corradini,E.,
            Kamler,M., Heck,A.J.R., Lehnart,S.E., Dobrev,D. and Wehrens,X.H.T.
  TITLE     Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor
            Type-2 Promotes Atrial Fibrillation
  JOURNAL   Circulation 142 (12), 1159-1172 (2020)
   PUBMED   32683896
  REMARK    GeneRIF: Loss of SPEG Inhibitory Phosphorylation of Ryanodine
            Receptor Type-2 Promotes Atrial Fibrillation.
REFERENCE   4  (bases 1 to 10782)
  AUTHORS   Levitas,A., Muhammad,E., Zhang,Y., Perea Gil,I., Serrano,R.,
            Diaz,N., Arafat,M., Gavidia,A.A., Kapiloff,M.S., Mercola,M.,
            Etzion,Y., Parvari,R. and Karakikes,I.
  TITLE     A Novel Recessive Mutation in SPEG Causes Early Onset Dilated
            Cardiomyopathy
  JOURNAL   PLoS Genet 16 (9), e1009000 (2020)
   PUBMED   32925938
  REMARK    GeneRIF: A Novel Recessive Mutation in SPEG Causes Early Onset
            Dilated Cardiomyopathy.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 10782)
  AUTHORS   Agrawal,P.B., Pierson,C.R., Joshi,M., Liu,X., Ravenscroft,G.,
            Moghadaszadeh,B., Talabere,T., Viola,M., Swanson,L.C.,
            Haliloglu,G., Talim,B., Yau,K.S., Allcock,R.J., Laing,N.G.,
            Perrella,M.A. and Beggs,A.H.
  TITLE     SPEG interacts with myotubularin, and its deficiency causes
            centronuclear myopathy with dilated cardiomyopathy
  JOURNAL   Am J Hum Genet 95 (2), 218-226 (2014)
   PUBMED   25087613
  REMARK    GeneRIF: SPEG is present in cardiac muscle, where it plays a
            critical role; therefore, individuals with SPEG mutations
            additionally present with dilated cardiomyopathy.
REFERENCE   6  (bases 1 to 10782)
  AUTHORS   Sutter,S.B., Raeker,M.O., Borisov,A.B. and Russell,M.W.
  TITLE     Orthologous relationship of obscurin and Unc-89: phylogeny of a
            novel family of tandem myosin light chain kinases
  JOURNAL   Dev Genes Evol 214 (7), 352-359 (2004)
   PUBMED   15185077
REFERENCE   7  (bases 1 to 10782)
  AUTHORS   Chen,Y.H., Layne,M.D., Watanabe,M., Yet,S.F. and Perrella,M.A.
  TITLE     Upstream stimulatory factors regulate aortic preferentially
            expressed gene-1 expression in vascular smooth muscle cells
  JOURNAL   J Biol Chem 276 (50), 47658-47663 (2001)
   PUBMED   11606591
REFERENCE   8  (bases 1 to 10782)
  AUTHORS   Hsieh,C.M., Fukumoto,S., Layne,M.D., Maemura,K., Charles,H.,
            Patel,A., Perrella,M.A. and Lee,M.E.
  TITLE     Striated muscle preferentially expressed genes alpha and beta are
            two serine/threonine protein kinases derived from the same gene as
            the aortic preferentially expressed gene-1
  JOURNAL   J Biol Chem 275 (47), 36966-36973 (2000)
   PUBMED   10973969
REFERENCE   9  (bases 1 to 10782)
  AUTHORS   Hsieh,C.M., Yet,S.F., Layne,M.D., Watanabe,M., Hong,A.M.,
            Perrella,M.A. and Lee,M.E.
  TITLE     Genomic cloning and promoter analysis of aortic preferentially
            expressed gene-1. Identification of a vascular smooth
            muscle-specific promoter mediated by an E box motif
  JOURNAL   J Biol Chem 274 (20), 14344-14351 (1999)
   PUBMED   10318857
REFERENCE   10 (bases 1 to 10782)
  AUTHORS   Hsieh,C.M., Yoshizumi,M., Endege,W.O., Kho,C.J., Jain,M.K.,
            Kashiki,S., de los Santos,R., Lee,W.S., Perrella,M.A. and Lee,M.E.
  TITLE     APEG-1, a novel gene preferentially expressed in aortic smooth
            muscle cells, is down-regulated by vascular injury
  JOURNAL   J Biol Chem 271 (29), 17354-17359 (1996)
   PUBMED   8663449
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC053503.7.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_005876.4.
            
            Summary: This gene encodes a protein with similarity to members of
            the myosin light chain kinase family. This protein family is
            required for myocyte cytoskeletal development. Along with the
            desmin gene, expression of this gene may be controlled by the
            desmin locus control region. Mutations in this gene are associated
            with centronuclear myopathy 5. [provided by RefSeq, Jun 2016].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer protein (isoform 1). This
            variant corresponds to the mouse SPEGbeta variant described in
            PubMed ID: 10973969.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968189,
                              SAMEA2142348 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000312358.12/ ENSP00000311684.7
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               AC053503.7         92647-92781
            136-523             AC053503.7         92782-93169
            524-613             AC053503.7         102457-102546
            614-950             AC053503.7         102629-102965
            951-2248            AC053503.7         105778-107075
            2249-2392           AC053503.7         108940-109083
            2393-2575           AC053503.7         109429-109611
            2576-2751           AC053503.7         119686-119861
            2752-2840           AC053503.7         120102-120190
            2841-3016           AC053503.7         122237-122412
            3017-3277           AC053503.7         124978-125238
            3278-3436           AC053503.7         126382-126540
            3437-3626           AC053503.7         126663-126852
            3627-3850           AC053503.7         126960-127183
            3851-3970           AC053503.7         129672-129791
            3971-4075           AC053503.7         130031-130135
            4076-4282           AC053503.7         130694-130900
            4283-4406           AC053503.7         131308-131431
            4407-4582           AC053503.7         131532-131707
            4583-4695           AC053503.7         134674-134786
            4696-4864           AC053503.7         135081-135249
            4865-4961           AC053503.7         135493-135589
            4962-5162           AC053503.7         135709-135909
            5163-5220           AC053503.7         136948-137005
            5221-5298           AC053503.7         137587-137664
            5299-5477           AC053503.7         137766-137944
            5478-5504           AC053503.7         138475-138501
            5505-5657           AC053503.7         139108-139260
            5658-5700           AC053503.7         139442-139484
            5701-5769           AC053503.7         140588-140656
            5770-7744           AC053503.7         140902-142876
            7745-7876           AC053503.7         143150-143281
            7877-7993           AC053503.7         145998-146114
            7994-8161           AC053503.7         146302-146469
            8162-8284           AC053503.7         146582-146704
            8285-8452           AC053503.7         146858-147025
            8453-9056           AC053503.7         147140-147743
            9057-9296           AC053503.7         148213-148452
            9297-9520           AC053503.7         148537-148760
            9521-9596           AC053503.7         149598-149673
            9597-9746           AC053503.7         149915-150064
            9747-10782          AC053503.7         150398-151433
FEATURES             Location/Qualifiers
     source          1..10782
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q35"
     gene            1..10782
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /note="striated muscle enriched protein kinase"
                     /db_xref="GeneID:10290"
                     /db_xref="HGNC:HGNC:16901"
                     /db_xref="MIM:615950"
     exon            1..523
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..9939
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     aortic preferentially expressed gene 1; aortic
                     preferentially expressed protein 1; nuclear protein,
                     marker for differentiated aortic smooth muscle and
                     down-regulated with vascular injury; striated muscle
                     preferentially expressed protein kinase; SPEG complex
                     locus"
                     /codon_start=1
                     /product="striated muscle preferentially expressed protein
                     kinase isoform 1"
                     /protein_id="NP_005867.3"
                     /db_xref="CCDS:CCDS42824.1"
                     /db_xref="GeneID:10290"
                     /db_xref="HGNC:HGNC:16901"
                     /db_xref="MIM:615950"
                     /translation="MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPV
                     FLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCGAQD
                     AGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTG
                     GSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRRLPGSPRQAQAT
                     GAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQ
                     SGLRREEPDLQPQLASEAPRRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTS
                     PHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRLSALGRSPR
                     LVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTP
                     GASQEELRAPGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSRE
                     ELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGD
                     EPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTK
                     APPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGP
                     WDRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVL
                     LKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATN
                     ELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQ
                     NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQR
                     RFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLA
                     PLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTS
                     VHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKIS
                     GTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAH
                     CSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKE
                     AMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVI
                     ANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTY
                     TVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQ
                     LLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGV
                     YELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDV
                     EVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDG
                     GVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRGRRLSDFYDIHQEIGRG
                     AFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFERRR
                     GLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLL
                     VWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVG
                     VVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVQDRLR
                     PTAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAP
                     PERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDE
                     ALGTPETGAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSA
                     ESALPRAGPRELGRGLHKAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRL
                     LRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFS
                     QGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPK
                     SAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQI
                     IQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGPPVLAEK
                     ARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEERGPFR
                     GAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRTPP
                     AQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSSEDSGGA
                     SGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEASATSGSSAP
                     GESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQYVRSESDFPPVFHIKLKDQVLL
                     EGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGL
                     YECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKPGDSRAPCTYTLE
                     RRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRG
                     TQDSSAVPSAAHQEAPVTSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPP
                     SQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTGTPIPAS
                     TPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPEPTKVTVQSLSPAKEVVSSPGS
                     SPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAE
                     GKRRVLQEYEVLRTLHHERIMSLHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSED
                     DVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPL
                     GHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGG
                     RFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFT
                     TNRLKEFLGEQRRRRAEAATRHKVLLRSYPGGP"
     exon            524..613
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            614..950
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            951..2248
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2392
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            2393..2575
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2751
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            2752..2840
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            2841..3016
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3277
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3436
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3437..3626
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3627..3850
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3851..3970
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            3971..4075
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4076..4282
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4283..4406
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4407..4582
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4583..4695
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4696..4864
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4865..4961
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            4962..5162
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5163..5220
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5221..5298
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5299..5477
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5478..5504
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5505..5657
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5658..5700
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5701..5769
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            5770..7744
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            7745..7876
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            7877..7993
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            7994..8161
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            8162..8284
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            8285..8452
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            8453..9056
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            9057..9296
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            9297..9520
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            9521..9596
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            9597..9746
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            9747..10782
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10763..10768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /note="hexamer: AATAAA"
     polyA_site      10782
                     /gene="SPEG"
                     /gene_synonym="APEG-1; APEG1; BPEG; CNM5; MYLK6;
                     SPEGalpha; SPEGbeta"
                     /note="major polyA site"
ORIGIN      
        1 agcacaggcc gaaggcgggc gggcagcagg aaggcaggcc gccggccccc cagacttgtc
       61 tcctagggca ccgtcccgcg ggtgcccccg tggccgccca gttccggcgt ccccccagcc
      121 cagctctcag tggccatgca gaaagcccgg ggcacgcgag gcgaggatgc gggcacgagg
      181 gcacccccca gccccggagt gcccccgaaa agggccaagg tgggggccgg cggcggggct
      241 cctgtggccg tggccggggc gccagtcttc ctgcggcccc tgaagaacgc ggcggtgtgc
      301 gcgggcagcg acgtgcggct gcgggtggtg gtgagcggga cgccccagcc cagcctccgc
      361 tggttccggg atgggcagct cctgcccgcg ccggcccccg agcccagctg cctgtggctg
      421 cggcgctgcg gggcgcagga cgccggcgtg tacagctgca tggcccagaa cgagcggggc
      481 cgggcctcct gcgaggcggt gctcacagtg ctggaggtcg gagactcaga gacggctgag
      541 gatgacatca gcgatgtgca gggaacccag cgcctggagc ttcgggatga cggggccttc
      601 agcaccccca cggggggttc tgacaccctg gtgggcacct ccctggacac acccccgacc
      661 tccgtgacag gcacctcaga ggagcaagtg agctggtggg gcagcgggca gacggtcctg
      721 gagcaggaag cgggcagtgg gggtggcacc cgccgcctcc cgggcagccc aaggcaagca
      781 caggcaaccg gggccgggcc acggcacctg ggggtggagc cgctggtgcg ggcatctcga
      841 gctaatctgg tgggcgcaag ctgggggtca gaggatagcc tttccgtggc cagtgacctg
      901 tacggcagcg cattcagcct gtacagagga cgggcgctct ctatccacgt cagcgtccct
      961 cagagcgggt tgcgcaggga ggagcccgac cttcagcctc aactggccag cgaagcccca
     1021 cgccgccctg cccagccgcc tccttccaaa tccgcgctgc tccccccacc gtcccctcgg
     1081 gtcgggaagc ggtccccgcc gggacccccg gcccagcccg cggccacccc cacgtcgccc
     1141 caccgtcgca ctcaggagcc tgtgctgccc gaggacacca ccaccgaaga gaagcgaggg
     1201 aagaagtcca agtcgtccgg gccctccctg gcgggcaccg cggaatcccg accccagacg
     1261 ccactgagcg aggcctcagg ccgcctgtcg gcgttgggcc gatcgcctag gctggtgcgc
     1321 gccggctccc gcatcctgga caagctgcag ttcttcgagg agcgacggcg cagcctggag
     1381 cgcagcgact cgccgccggc gcccctgcgg ccctgggtgc ccctgcgcaa ggcccgctct
     1441 ctggagcagc ccaagtcgga gcgcggcgca ccgtggggca cccccggggc ctcgcaggaa
     1501 gaactgcggg cgccaggcag cgtggccgag cggcgccgcc tgttccagca gaaagcggcc
     1561 tcgctggacg agcgcacgcg tcagcgcagc ccggcctcag acctcgagct gcgcttcgcc
     1621 caggagctgg gccgcatccg ccgctccacg tcgcgggagg agctggtgcg ctcgcacgag
     1681 tccctgcgcg ccacgctgca gcgtgcccca tcccctcgag agcccggcga gcccccgctc
     1741 ttctctcggc cctccacccc caagacatcg cgggccgtga gccccgccgc cgcccagccg
     1801 ccctctccga gcagcgcgga gaagccgggg gacgagcctg ggaggcccag gagccgcggg
     1861 ccggcgggca ggacagagcc gggggaaggc ccgcagcagg aggttaggcg tcgggaccaa
     1921 ttcccgctga cccggagcag agccatccag gagtgcagga gccctgtgcc gccccccgcc
     1981 gccgatcccc cagaggccag gacgaaagca ccccccggtc ggaagcggga gcccccggcg
     2041 caggccgtgc gcttcctgcc ctgggccacg ccgggcctgg agggcgctgc tgtaccccag
     2101 accttggaga agaacagggc ggggcctgag gcagagaaga ggcttcgcag agggccggag
     2161 gaggacggtc cctgggggcc ctgggaccgc cgaggggccc gcagccaggg caaaggtcgc
     2221 cgggcccggc ccacctcccc tgagctcgag tcttcggatg actcctacgt gtccgctgga
     2281 gaagagcccc tagaggcccc tgtgtttgag atccccctgc agaatgtggt ggtggcacca
     2341 ggggcagatg tgctgctcaa gtgtatcatc actgccaacc ccccgcccca agtgtcctgg
     2401 cacaaggatg ggtcagcgct gcgcagcgag ggccgcctcc tcctccgggc tgagggtgag
     2461 cggcacaccc tgctgctcag ggaggccagg gcagcagatg ccgggagcta tatggccacc
     2521 gccaccaacg agctgggcca ggccacctgt gccgcctcac tgaccgtgag acccggtggg
     2581 tctacatccc ctttcagcag ccccatcacc tccgacgagg aatacctgag ccccccagag
     2641 gagttcccag agcctgggga gacctggccg cgaaccccca ccatgaagcc cagtcccagc
     2701 cagaaccgcc gttcttctga cactggctcc aaggcacccc ccaccttcaa ggtctcactt
     2761 atggaccagt cagtaagaga aggccaagat gtcatcatga gcatccgcgt gcagggggag
     2821 cccaagcctg tggtctcctg gctgagaaac cgccagcccg tgcgcccaga ccagcggcgc
     2881 tttgcggagg aggctgaggg tgggctgtgc cggctgcgga tcctggctgc agagcgtggc
     2941 gatgctggtt tctacacttg caaagcggtc aatgagtatg gtgctcggca gtgcgaggcc
     3001 cgcttggagg tccgagcaca ccctgaaagc cggtccctgg ccgtgctggc ccccctgcag
     3061 gacgtggacg tgggggccgg ggagatggcg ctgtttgagt gcctggtggc ggggcccact
     3121 gacgtggagg tggattggct gtgccgtggc cgcctgctgc agcctgcact gctcaaatgc
     3181 aagatgcatt tcgatggccg caaatgcaag ctgctactta catctgtaca tgaggacgac
     3241 agtggcgtct acacctgcaa gctcagcacg gccaaagatg agctgacctg cagtgcccgg
     3301 ctgaccgtgc ggccctcgtt ggcacccctg ttcacacggc tgctggaaga tgtggaggtg
     3361 ttggagggcc gagctgcccg tttcgactgc aagatcagtg gcaccccgcc ccctgttgtt
     3421 acctggactc attttggctg ccccatggag gagagtgaga acttgcggct gcggcaggac
     3481 gggggtctgc actcactgca cattgcccat gtgggcagcg aggacgaggg gctctatgcg
     3541 gtcagtgctg ttaacaccca tggccaggcc cactgctcag cccagctgta tgtagaagag
     3601 ccccggacag ccgcctcagg ccccagctcg aagctggaga agatgccatc cattcccgag
     3661 gagccagagc agggtgagct ggagcggctg tccattcctg acttcctgcg gccactgcag
     3721 gacctggagg tgggactggc caaggaggcc atgctagagt gccaggtgac cggcctgccc
     3781 taccccacca tcagctggtt ccacaatggc caccgcatcc agagcagcga cgaccggcgc
     3841 atgacacagt acagggatgt ccatcgcttg gtgttccctg ccgtggggcc tcagcacgcc
     3901 ggtgtctaca agagcgtcat tgccaacaag ctgggcaaag ctgcctgcta tgcccacctg
     3961 tatgtcacag atgtggtccc aggccctcca gatggcgccc cgcaggtggt ggctgtgacg
     4021 gggaggatgg tcacactcac atggaacccc cccaggagtc tggacatggc catcgacccg
     4081 gactccctga cgtacacagt gcagcaccag gtgctgggct cggaccagtg gacggcactg
     4141 gtcacaggcc tgcgggagcc agggtgggca gccacagggc tgcgtaaggg ggtccagcac
     4201 atcttccggg tcctcagcac cactgtcaag agcagcagca agccctcacc cccttctgag
     4261 cctgtgcagc tgctggagca cggcccaacc ctggaggagg cccctgccat gctggacaaa
     4321 ccagacatcg tgtatgtggt ggagggacag cctgccagcg tcaccgtcac attcaaccat
     4381 gtggaggccc aggtcgtctg gaggagctgc cgaggggccc tcctagaggc acgggccggt
     4441 gtgtacgagc tgagccagcc agatgatgac cagtactgtc ttcggatctg ccgggtgagc
     4501 cgccgggaca tgggggccct cacctgcacc gcccgaaacc gtcacggcac acagacctgc
     4561 tcggtcacat tggagctggc agaggcccct cggtttgagt ccatcatgga ggacgtggag
     4621 gtgggggctg gggaaactgc tcgctttgcg gtggtggtcg agggaaaacc actgccggac
     4681 atcatgtggt acaaggacga ggtgctgctg accgagagca gccatgtgag cttcgtgtac
     4741 gaggagaatg agtgctccct ggtggtgctc agcacggggg cccaggatgg aggcgtctac
     4801 acctgcaccg cccagaacct ggcgggtgag gtctcctgca aagcagagtt ggctgtgcat
     4861 tcagctcaga cagctatgga ggtcgagggg gtcggggagg atgaggacca tcgaggaagg
     4921 agactcagcg acttttatga catccaccag gagatcggca ggggtgcttt ctcctacttg
     4981 cggcgcatag tggagcgtag ctccggcctg gagtttgcgg ccaagttcat ccccagccag
     5041 gccaagccaa aggcatcagc gcgtcgggag gcccggctgc tggccaggct ccagcacgac
     5101 tgtgtcctct acttccatga ggccttcgag aggcgccggg gactggtcat tgtcaccgag
     5161 ctctgcacag aggagctgct ggagcgaatc gccaggaaac ccaccgtgtg tgagtctgag
     5221 atccgggcct atatgcggca ggtgctagag ggaatacact acctgcacca gagccacgtg
     5281 ctgcacctcg atgtcaagcc tgagaacctg ctggtgtggg atggtgctgc gggcgagcag
     5341 caggtgcgga tctgtgactt tgggaatgcc caggagctga ctccaggaga gccccagtac
     5401 tgccagtatg gcacacctga gtttgtagca cccgagattg tcaatcagag ccccgtgtct
     5461 ggagtcactg acatctggcc tgtgggtgtt gttgccttcc tctgtctgac aggaatctcc
     5521 ccgtttgttg gggaaaatga ccggacaaca ttgatgaaca tccgaaacta caacgtggcc
     5581 ttcgaggaga ccacattcct gagcctgagc agggaggccc ggggcttcct catcaaagtg
     5641 ttggtgcagg accggctgag acctaccgca gaagagaccc tagaacatcc ttggttcaaa
     5701 actcaggcaa agggcgcaga ggtgagcacg gatcacctga agctattcct ctcccggcgg
     5761 aggtggcagc gctcccagat cagctacaaa tgccacctgg tgctgcgccc catccccgag
     5821 ctgctgcggg cccccccaga gcgggtgtgg gtgaccatgc ccagaaggcc accccccagt
     5881 ggggggctct catcctcctc ggattctgaa gaggaagagc tggaagagct gccctcagtg
     5941 ccccgcccac tgcagcccga gttctctggc tcccgggtgt ccctcacaga cattcccact
     6001 gaggatgagg ccctggggac cccagagact ggggctgcca cccccatgga ctggcaggag
     6061 cagggaaggg ctccctctca ggaccaggag gctcccagcc cagaggccct cccctcccca
     6121 ggccaggagc ccgcagctgg ggctagcccc aggcggggag agctccgcag gggcagctcg
     6181 gctgagagcg ccctgccccg ggccgggccg cgggagctgg gccggggcct gcacaaggcg
     6241 gcgtctgtgg agctgccgca gcgccggagc cccagcccgg gagccacccg cctggcccgg
     6301 ggaggcctgg gtgagggcga gtatgcccag aggctgcagg ccctgcgcca gcggctgctg
     6361 cggggaggcc ccgaggatgg caaggtcagc ggcctcaggg gtcccctgct ggagagcctg
     6421 gggggccgtg ctcgggaccc ccggatggca cgagctgcct ccagcgaggc agcgccccac
     6481 caccagcccc cactcgagaa ccggggcctg caaaagagca gcagcttctc ccagggtgag
     6541 gcggagcccc ggggccggca ccgccgagcg ggggcgcccc tcgagatccc cgtggccagg
     6601 cttggggccc gtaggctaca ggagtctcct tccctgtctg ccctcagcga ggcccagcca
     6661 tccagccctg cacggcccag cgcccccaaa cccagtaccc ctaagtctgc agaaccttct
     6721 gccaccacac ctagtgatgc tccgcagccc cccgcacccc agcctgccca agacaaggct
     6781 ccagagccca ggccagaacc agtccgagcc tccaagcctg caccaccccc ccaggccctg
     6841 caaaccctag cgctgcccct cacaccctat gctcagatca ttcagtccct ccagctgtca
     6901 ggccacgccc agggcccctc gcagggccct gccgcgccgc cttcagagcc caagccccac
     6961 gctgctgtct ttgccagggt ggcctcccca cctccgggag cccccgagaa gcgcgtgccc
     7021 tcagccgggg gtcccccggt gctagccgag aaagcccgag ttcccacggt gccccccagg
     7081 ccaggcagca gtctcagtag cagcatcgaa aacttggagt cggaggccgt gttcgaggcc
     7141 aagttcaagc gcagccgcga gtcgcccctg tcgctggggc tgcggctgct gagccgttcg
     7201 cgctcggagg agcgcggccc cttccgtggg gccgaggagg aggatggcat ataccggccc
     7261 agcccggcgg ggaccccgct ggagctggtg cgacggcctg agcgctcacg ctcggtgcag
     7321 gacctcaggg ctgtcggaga gcctggcctc gtccgccgcc tctcgctgtc actgtcccag
     7381 cggctgcggc ggacccctcc cgcgcagcgc cacccggcct gggaggcccg cggcggggac
     7441 ggagagagct cggagggcgg gagctcggcg cggggctccc cggtgctggc gatgcgcagg
     7501 cggctgagct tcaccctgga gcggctgtcc agccgattgc agcgcagtgg cagcagcgag
     7561 gactcggggg gcgcgtcggg ccgcagcacg ccgctgttcg gacggcttcg cagggccacg
     7621 tccgagggcg agagtctgcg gcgccttggc cttccgcaca accagttggc cgcccaggcc
     7681 ggcgccacca cgccttccgc cgagtccctg ggctccgagg ccagcgccac gtcgggctcc
     7741 tcagccccag gggaaagccg aagccggctc cgctggggct tctctcggcc gcggaaggac
     7801 aaggggttat cgccaccaaa cctctctgcc agcgtccagg aggagttggg tcaccagtac
     7861 gtgcgcagtg agtcagactt ccccccagtc ttccacatca aactcaagga ccaggtgctg
     7921 ctggaggggg aggcagccac cctgctctgc ctgccagcgg cctgccctgc accgcacatc
     7981 tcctggatga aagacaagaa gtccttgagg tcagagccct cagtgatcat cgtgtcctgc
     8041 aaagatgggc ggcagctgct cagcatcccc cgggcgggca agcggcacgc cggtctctat
     8101 gagtgctcgg ccaccaacgt actgggcagc atcaccagct cctgtaccgt ggctgtggcc
     8161 cgagtcccag gaaagctagc tcctccagag gtaccccaga cctaccagga cacggcgctg
     8221 gtgctgtgga agccgggaga cagccgggca ccttgcacgt atacgctgga gcggcgagtg
     8281 gatggggagt ctgtgtggca ccctgtgagc tcaggcatcc ccgactgtta ctacaacgtg
     8341 acccacctgc cagttggcgt gactgtgagg ttccgtgtgg cctgtgccaa ccgtgctggg
     8401 caggggccct tcagcaactc ttctgagaag gtctttgtca ggggtactca agattcttca
     8461 gctgtgccat ctgctgccca ccaagaggcc cctgtcacct caaggccagc cagggcccgg
     8521 cctcctgact ctcctacctc actggcccca cccctagctc ctgctgcccc cacacccccg
     8581 tcagtcactg tcagcccctc atctcccccc acacctccta gccaggcctt gtcctcgctc
     8641 aaggctgtgg gtccaccacc ccaaacccct ccacgaagac acaggggcct gcaggctgcc
     8701 cggccagcgg agcccaccct acccagtacc cacgtcaccc caagtgagcc caagcctttc
     8761 gtccttgaca ctgggacccc gatcccagcc tccactcctc aaggggttaa accagtgtct
     8821 tcctctactc ctgtgtatgt ggtgacttcc tttgtgtctg caccaccagc ccctgagccc
     8881 ccagcccctg agccccctcc tgagcctacc aaggtgactg tgcagagcct cagcccggcc
     8941 aaggaggtgg tcagctcccc tgggagcagt ccccgaagct ctcccaggcc tgagggtacc
     9001 actcttcgac agggtccccc tcagaaaccc tacaccttcc tggaggagaa agccaggggc
     9061 cgctttggtg ttgtgcgagc gtgccgggag aatgccacgg ggcgaacgtt cgtggccaag
     9121 atcgtgccct atgctgccga gggcaagcgg cgggtcctgc aggagtacga ggtgctgcgg
     9181 accctgcacc acgagcggat catgtccctg cacgaggcct acatcacccc tcggtacctc
     9241 gtgctcattg ctgagagctg tggcaaccgg gaactcctct gtgggctcag tgacaggttc
     9301 cggtattctg aggatgacgt ggccacttac atggtgcagc tgctacaagg cctggactac
     9361 ctccacggcc accacgtgct ccacctagac atcaagccag acaacctgct gctggcccct
     9421 gacaatgccc tcaagattgt ggactttggc agtgcccagc cctacaaccc ccaggccctt
     9481 aggccccttg gccaccgcac gggcacgctg gagttcatgg ctccggagat ggtgaaggga
     9541 gaacccatcg gctctgccac ggacatctgg ggagcgggtg tgctcactta cattatgctc
     9601 agtggacgct ccccgttcta tgagccagac ccccaggaaa cggaggctcg gattgtgggg
     9661 ggccgctttg atgccttcca gctgtacccc aatacatccc agagcgccac cctcttcttg
     9721 cgaaaggttc tctctgtaca tccctggagc cggccctccc tgcaggactg cctggcccac
     9781 ccatggttgc aggacgccta cctgatgaag ctgcgccgcc agacgctcac cttcaccacc
     9841 aaccggctca aggagttcct gggcgagcag cggcggcgcc gggctgaggc tgccacccgc
     9901 cacaaggtgc tgctgcgctc ctaccctggc ggcccctaga ggcacggacc acagccaggc
     9961 ctcgggcttc aactggggtt cccaccaatg ccacgggaca ttccagggcc cacgctgagc
    10021 caggcgggcc tggggcttcg gttaccacca gcagcaacat ctggctgggc tcttacctca
    10081 tagaccttca aggacagaga ccccagggcc tggacctgat gccaccccag gccaaagcca
    10141 gagtgggaga cccattggtc aggctcagca gggtgggaac aggcagaggg acaagagggg
    10201 aatggagaag tggagaggaa aaggaatcga gggacaggaa gggggaggct ctaggaaggt
    10261 tctgggttgg gggtcagtgc atctcaggga gaaccaagga aggtgggcat ggctggagag
    10321 gaggaaaagg aaggagcccc aggtgtcagg gcagtaggct gggagtcagt gtggcaaagc
    10381 gggggcagga cacagataca gtggcagggg cccagggctg ggacatgaga gaaggcagcg
    10441 aggcggcaga gggagaagag aggactcagg tggaggtggg gtgggtcagc tgtcagcatc
    10501 cctcagagga gaaatgtgga gagctggagg ccagcagtca ctcacactcg ctctgtcctc
    10561 ctgtccagtg gatacagccc tgggcgctct gctggcccaa ggatgtcccc actgcccctc
    10621 catggcctct ggccttcttc ccattcatat ttatttattt attgactttt atgaagtttc
    10681 cccttccatc cgatccctac tgcccatgtt gtcctgacca tccctcccag ccatccagct
    10741 gtctgtctgt ctgccacaag gaaataaaaa tggcaagcag ca
//
