LOCUS       NM_001382525            2900 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens speedy/RINGO cell cycle regulator family member E8
            (SPDYE8), mRNA.
ACCESSION   NM_001382525
VERSION     NM_001382525.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2900)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2900)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   3  (bases 1 to 2900)
  CONSRTM   Sanger Center; Genome Sequencing Center
  TITLE     Toward a complete human genome sequence
  JOURNAL   Genome Res 8 (11), 1097-1108 (1998)
   PUBMED   9847074
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC211476.5.
            
            On May 11, 2021 this sequence version replaced NM_001382525.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000333385.11/ ENSP00000498819.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AC211476.5         75342-75463
            123-705             AC211476.5         76689-77271
            706-924             AC211476.5         78255-78473
            925-983             AC211476.5         79507-79565
            984-1069            AC211476.5         80793-80878
            1070-1313           AC211476.5         82584-82827
            1314-1418           AC211476.5         82950-83054
            1419-2900           AC211476.5         83908-85389
FEATURES             Location/Qualifiers
     source          1..2900
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q11.23"
     gene            1..2900
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /note="speedy/RINGO cell cycle regulator family member E8"
                     /db_xref="GeneID:728524"
                     /db_xref="HGNC:HGNC:33771"
     exon            1..122
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            123..705
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     CDS             576..1373
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /note="Williams Beuren syndrome chromosome region 19
                     pseudogene; speedy homolog E pseudogene; speedy/RINGO cell
                     cycle regulator family member E1 pseudogene; speedy
                     homolog E8, pseudogene; speedy/RINGO cell cycle regulator
                     family member E8, pseudogene"
                     /codon_start=1
                     /product="putative speedy protein E8"
                     /protein_id="NP_001369454.1"
                     /db_xref="CCDS:CCDS94114.1"
                     /db_xref="GeneID:728524"
                     /db_xref="HGNC:HGNC:33771"
                     /translation="MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSA
                     PGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVS
                     LVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIH
                     FFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQ
                     IALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS"
     exon            706..924
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            925..983
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1069
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1313
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1418
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
     exon            1419..2900
                     /gene="SPDYE8"
                     /gene_synonym="SPDYE8P; SPDYE9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacaatggga cttccacagc aatgggattt ccttccgcat tcagtttgtg cctttcccat
       61 gagcgagaga ctcctaggag agccgcagcc cgttaggaag ccatgtggga actcatccac
      121 agactggact ctgaaacggg catgtacaga gaagaggaga ccccaacacg cttcaagctt
      181 tgagtggaga ggacacagcc tctgctggga cagggaacag agggatgcgg agaccctgaa
      241 gatgcttttg gacagtggtc tgaggttggg acagtggcag gagataccat tcacccagga
      301 tctccaggac aagagatcag cctggcagtt acatgtgttt tttttcaaac tggttgccag
      361 gttggcatga gcgatgacat cagagattcc gaccttcctg attggaggga ccggactctg
      421 tcggcacctg ggagttcagt tggacaacag taacttctca gagctgttct ccactcctga
      481 cttctcccag cctcgagaat tgataacaca ctcttctgga tcccagcagt gtccagaaga
      541 agaccaagga cagaacagag actaggtttg gtgagatggg acagattttg ggaaagatca
      601 tgatgagcca tcaaccgcag ccccaggaag agcggagccc ccagcggagc acctcagggt
      661 accccctcca ggaggtggtg gatgatgaag tgtcgggacc atcagcccct ggggtagatc
      721 ccagcccccc acgtaggtcc cttggctgga aaaggaagag ggaatgtttg gatgaatctg
      781 atgatgagcc agagaaggag ctcgcccctg agcctgagga gacctgggtg gcggagacgc
      841 tgtgtggcct caagatgaag gcgaagcgac ggcgagtgtc gctcgtgctc cctgagtact
      901 acgaggcctt caacaggctg cttgaggatc ctgtcattaa aagactcctg gcctgggaca
      961 aagatctgag ggtgtcggac aagtatctcc tggctatggt catagcgtat ttcagccggg
     1021 ccggcctccc ctcctggcaa taccaacgca ttcatttctt cctggctctc tatctggcca
     1081 atgacatgga ggaggacgac gaggccccca aacaaaacat cttctacttc ctgtacgagg
     1141 agacccgctc tcatataccc ttgctcagtg agctttggtt ccagttatgc cgttacatga
     1201 acccgagggc caggaagaac tgctctcaga tagccttgtt ccggaagtat cggttccact
     1261 tcttttgttc catgcgctgc agggcttggg tttccctgga ggagttggaa gagatccagg
     1321 cttatgaccc agagcactgg gtgtgggcgc gagatcgcgc ccacctttcc tagagctcca
     1381 gggaccgtgg aggcctgagg tcatcggcct gagagaagaa caccggaccc aggggagatg
     1441 tggattttca gcaggaactt tattccaatg ctaatggcag acatcaggaa ggaggagagg
     1501 aaccatttgt gcagatcatc tagaagaacc tggaccattc ttgacagagc tgaatacagt
     1561 gatcacgttg tcctccaagg agcaggggtg gggtggggta cttctaggag tccttggaga
     1621 aaagtaagaa accaggagtg tttccagttc caccctttcc tgcggcacca cctccctttt
     1681 tatattgctg aatgccaacc tccctggggc ggaacctgga ggtcctgttt cttatggact
     1741 tggttgtcac agtccaggag catttgaagg cacagtgcag gggctcagat tggcacagaa
     1801 ttctttgtga aatatgagtg ccacagactg taacagatag cttcatgcac actatgcatt
     1861 ttattggttt gtttggaaaa tgttggccat tgaattatta ataggtttat ttcaaatagt
     1921 ttggaaattg ttgtactttt gaaaacatgc tgttcctgta gagttttttg atgagagtta
     1981 tagttgttat atatacctaa agataatttt cttttcattt ttaagtgaga attcttttta
     2041 tcctaaatct tttattatct ttaatttttt ttctgtatta ttatatgtgc tcctgaagcg
     2101 agcactcttt ttatctatga tacttccata ataatctctt ctatttatag ctattggtag
     2161 ttccccacca gaaaaaaaca taattctggt gatagaaatt tttatttgct gtttaggttt
     2221 gtgactgact tgtgagaatt cagttgtgat ttttaacatg tctcagatat atatactaac
     2281 acgtctaata tatactatct attttattgg tttattttga aaaacatggg tatagaatta
     2341 tttaaatatt attttattta ctgaaatatt tattaaatat atttatttat ttaaatatta
     2401 ttattacttt aaatattatt ttaaatattt tggaaatact ggtatttttg aatagatgct
     2461 gtttctataa agctgtgtga tgggtattat aactgttgta tacacataca tataattttg
     2521 ttttcctttt taagagagga ttcttttcat cctaaatctt ttacctttca atctttgtat
     2581 ctattattac acgtgctgct gaagggagca tggtttttat ctatgatact tagttaacat
     2641 atatattaca tttatagcta tgtggtagtt cccctaaatt cttgtaaaaa taaattttta
     2701 tttgatattt agtgtatgtt tgaaatgtga gaattcagat ggaatttttt atcttgtttt
     2761 ggcatgtttg tatgttactt taaagaggat gtgtgttcta aaggaggaca tgagctgtgt
     2821 gttttcaaga gaacagtgca gtgcatctct tggggaaaca taataaagat gaacttttct
     2881 caccttcaca gtgagtgtga
//
