LOCUS       NM_001004351            3185 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens speedy/RINGO cell cycle regulator family member E3
            (SPDYE3), mRNA.
ACCESSION   NM_001004351 XM_496911
VERSION     NM_001004351.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3185)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC056606.1 and BC100972.2.
            
            On Jun 2, 2019 this sequence version replaced NM_001004351.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056606.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000332397.6/ ENSP00000329565.6
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1191              BC056606.1         2-1192
            1192-1425           BC100972.2         117-350
            1426-3185           BC056606.1         1427-3186
FEATURES             Location/Qualifiers
     source          1..3185
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..3185
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /note="speedy/RINGO cell cycle regulator family member E3"
                     /db_xref="GeneID:441272"
                     /db_xref="HGNC:HGNC:35462"
                     /db_xref="MIM:617625"
     exon            1..290
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..1834
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /note="putative Speedy protein E3; Putative WBSCR19-like
                     protein 7; speedy homolog E3"
                     /codon_start=1
                     /product="speedy protein E3"
                     /protein_id="NP_001004351.3"
                     /db_xref="CCDS:CCDS47658.2"
                     /db_xref="GeneID:441272"
                     /db_xref="HGNC:HGNC:35462"
                     /db_xref="MIM:617625"
                     /translation="MTSHQPQPQEEQSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPP
                     RRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYE
                     AFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMK
                     AKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEP
                     EETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECL
                     DESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPS
                     PPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEY
                     YEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALY
                     LANDMEEDDEAPKQKIFYFLYGKTHSHIPLRPKHWFQLCRPMNPRARKNCSQIALFQK
                     RRFQFFCSMRCRAWVSPEELEEIQAYDPEHWVWARDRAHLS"
     exon            291..509
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            510..728
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            729..947
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1166
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1385
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1444
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1530
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1774
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1879
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..3185
                     /gene="SPDYE3"
                     /gene_synonym="SPDYB2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgtcggc gcctggcagt tcaggtgaac aacagtaact tctcagagct gttctccact
       61 cctgacttct cccagcctcg agaattgata acacactctt ctggatccca gcagtgtcca
      121 gaagaagacc aaggacagaa cagagactag cttcggtgag attggacaga ttttgggaaa
      181 gatcatgacg agccatcaac cgcagcccca ggaagagcag agcccccagc ggagcacctc
      241 agggtacccc ctccaggagg tggtggatga tgaagtgtcg ggaccatcag cccctggggt
      301 agatcccagc cccccacgta ggtcccttgg ctgcaaaagg aagagggagt gtttggatga
      361 atctgatgat gagccagaga aggagctcgc ccctgagcct gaggagacct gggtggcgga
      421 gacgctgtgt ggcctcaaga tgaaggcgaa gcgacggcga gtgtcgctcg tgctccctga
      481 gtactacgag gccttcaaca ggctgcttgc ccctggggta gatcccagcc ccccacgtag
      541 gtcccttggc tgcaaaagga agagggagtg tttggatgaa tctgatgatg agccagagaa
      601 ggagctcgcc cctgagcctg aggagacctg ggtggcggag acgctgtgtg gcctcaagat
      661 gaaggcgaag cgacggcgag tgtcgctcgt gctccctgag tactacgagg ccttcaacag
      721 gctgcttgcc cctggggtag atcccagccc cccacgtagg tcccttggct gcaaaaggaa
      781 gagggagtgt ttggatgaat ctgatgatga gccagagaag gagctcgccc ctgagcctga
      841 ggagacctgg gtggcagaga cgctgtgtgg cctcaagatg aaggcgaagc gacggcgagt
      901 gtcgctcgtg ctccctgagt actacgaggc cttcaacagg ctgcttgccc ctggggtaga
      961 tcccagcccc ccacgtaggt cccttggctg caaaaggaag agggagtgtt tggatgaatc
     1021 tgatgatgag ccagagaagg agctcgcccc tgagcctgag gagacctggg tggcggagac
     1081 gctgtgtggc ctcaagatga aggcgaagcg acggcgagtg tcgctcgtgc tccctgagta
     1141 ctacgaggcc ttcaacaggc tgcttgcccc tggggtagat cccagccccc cgcgtaggtc
     1201 ccttggctgc aaaaggaaga gggagtgttt ggatgaatct gatgatgagc cagagaagga
     1261 gctcgcccct gagcctgagg agacctgggt ggcggagacg ctgtgtggcc tcaagatgaa
     1321 ggcgaagcga cggcgagtgt cgctcgtgct ccctgagtac tacgaggcct tcaacaggct
     1381 gcttgaggat cctgtcatta aaagattcct ggcctgggac aaagatctga gggtgtcaga
     1441 caagtatctc ctggctatgg tcatagcgta tttcagccgg gccggcctcc cctcctggca
     1501 ataccaacgc attcatttct tcctggctct ctatctggcc aatgacatgg aggaggacga
     1561 cgaggccccc aaacaaaaga tcttctactt cctgtacggg aagacccact ctcacatacc
     1621 cttgcgccct aagcattggt tccagttatg ccgtcccatg aacccgaggg ccaggaagaa
     1681 ctgctctcag atagccttgt tccagaagcg tcggttccag ttcttctgtt ccatgcgctg
     1741 cagggcttgg gtttccccgg aggagttgga ggagatccag gcttatgacc cagagcactg
     1801 ggtgtgggcg cgagatcgcg cccacctttc ctagagctcc agggaccgtg gaggcctgag
     1861 gtcatcggcc tgagagaaga acaccggacc caggggagat gtggattttc agcaggaact
     1921 ttattccagt gctaatggca gacatcagga aggaggagag gagccatttg tgcagatcat
     1981 ctagaagaac ctggaccatt cttgacagag ctgaatacag tgatcacgtt gtcctccaag
     2041 gagcaggggt ggggtggggt acttctagga gtccttggag aaaagtaaga aaccaggagt
     2101 gtttccagtt ccaccctttc ctgcggcacc acctcccttt ttatattgct gaatgccaac
     2161 ctccctgggg cggaacctgg aggtcctgtt tcttacggac ttggttgcca cagtccagga
     2221 gcatttgaag gcacagtgca ggggctcaga ttggcacaga attctttgtg aaatatgagt
     2281 gccacagact gtaacagata gcttcatgca cactatgcat tttattggtt tgtttggaaa
     2341 atgttggcca ttgaatcatt aataggttta tttcaaatag tttggaaatt gttgtacttt
     2401 tgaaaacatg ctgttcctgt agagtttttt gatgagagtt atagttgtta tatatacata
     2461 aagataattt tcttttcatt tttaagtgag aattcttttt atcctaaatc ttttattatc
     2521 tttaaatttt tctctgtatt attatatgtg ctcctgaagc gagcactctt tttatctatg
     2581 atacttccat aataatctct tctatttata gctattggta gttcccccaa attctggtca
     2641 tagaaatttt tatttgctgt ttaggtttgt gactgaattg tgagaattca gttgtgattt
     2701 ttaacatgtc ttagatatat atactaacat gtctaatata tactatctat tttattgatt
     2761 tatttcgaaa aagatgggca aagaattatt taaatattat tttatttatt taaatattta
     2821 ttaaatatat ttatttattt aaatatttat taaatatatt tatttattta aatgttatta
     2881 ctttaaatat tattttaaat attttggaaa tactggtatt tttgaataga tgctgtttct
     2941 ataaagctgt gtgatgggta ttataactgt tatatacaca taaatataat tttgttttcc
     3001 tttttaagag aggattcttt ttatcctaaa tcttttacct ttcaatcttt gtatctatta
     3061 ctacatatgc tgctgaaggg agcagacttt ttatctatga tacttagtta atgtatatat
     3121 tacatttata gctatgtggt agttccccta aattcttgta aaaataaatt tttatttgat
     3181 attta
//
