LOCUS       NM_001166339            3214 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens speedy/RINGO cell cycle regulator family member E2B
            (SPDYE2B), mRNA.
ACCESSION   NM_001166339 XM_499356 XM_935540
VERSION     NM_001166339.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3214)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC105052.3.
            
            On May 12, 2021 this sequence version replaced NM_001166339.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: This CCDS representation lacks full-length human
            transcript support. Its exon combination is therefore inferred, but
            it is supported by a full-length orthologous mouse transcript,
            AK302217.1, and partial human transcripts.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000507450.6/ ENSP00000424058.1
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                AC105052.3         64060-64118
            60-640              AC105052.3         65669-66249
            641-859             AC105052.3         67192-67410
            860-1090            AC105052.3         68725-68955
            1091-1149           AC105052.3         69989-70047
            1150-1235           AC105052.3         71292-71377
            1236-1629           AC105052.3         73431-73824
            1630-1734           AC105052.3         73947-74051
            1735-3214           AC105052.3         74887-76366
FEATURES             Location/Qualifiers
     source          1..3214
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..3214
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /note="speedy/RINGO cell cycle regulator family member
                     E2B"
                     /db_xref="GeneID:100310812"
                     /db_xref="HGNC:HGNC:48334"
     exon            1..59
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            60..640
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     CDS             481..1689
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /note="putative speedy protein E2-like protein; putative
                     WBSCR19-like protein 3"
                     /codon_start=1
                     /product="speedy protein E2B"
                     /protein_id="NP_001159811.1"
                     /db_xref="CCDS:CCDS59507.1"
                     /db_xref="GeneID:100310812"
                     /db_xref="HGNC:HGNC:48334"
                     /translation="MDRTETRFRKRGQITGKITTSRQPHPQNEQSPQRSTSGYPLQEV
                     VDDEMLGPSAPGVDPSPPCRSLGWKRKREWSDESEEEPEKELAPEPEETWVVEMLCGL
                     KMKLKQQRVSSILPEHHKDFNSQLAPGVDPSPPHRSFCWKRKMEWWDESEESLEEEPR
                     KVLAPEPEEIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDL
                     RVSDKYLLAMVIAYFSRAGFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYRK
                     NRSRIPLLRKPWFQLGHSMNPRARKNRSRIPLLRKRRFQLYRSTNPRARKNRSRIPLL
                     RKRRFQLYRSMNSRARKNRSQIVLFQKRRFHFFCSMSCRAWVSPEELEEIQAYDPEHW
                     VWARDRAHLS"
     exon            641..859
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1090
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1149
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1235
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1629
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1734
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..3214
                     /gene="SPDYE2B"
                     /gene_synonym="SPDYE2L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accctcagca gagacagacc ccagatctgg gcccaggact ttgtgcaggg aggggaaata
       61 ctggactctg aaatgggcat gtacagagac gaagagaccc caacatgctt caggctttga
      121 gtggagagga cacagcctct gctgggacag ggaatagagg gatgtggagt ccctgaagat
      181 gcttttggac aatggtctga ggttgggaca gtggcaggag ataccattca cccaggatct
      241 ccaggacaag agatcagcct ggcagttaca tgtgtttttt ttcaaactgg ttgccaggtt
      301 ggcatgaacg atgacatcag agattccgac cttcctgatt ggagggaccg gactccgtgg
      361 tgcctggaga tcagttggac aacagtatct tctcagagct gttctctact cctgacttct
      421 cctaggcttg agaattgata acatactctt ctggatccta gaagtgtcca gaagaaggcc
      481 atggacagaa cggagactag gttccgtaag aggggacaga ttacgggaaa gatcacgacc
      541 agccgtcaac cgcaccccca gaatgagcag agtccccagc ggagcacctc ggggtacccc
      601 ctccaggagg tggtggatga tgaaatgttg ggaccatcag cccctggggt agatcccagc
      661 cccccatgta ggtcccttgg ctggaaaagg aagagggagt ggtcagatga atctgaggag
      721 gagccggaga aggagctcgc ccctgagcct gaggagacct gggtagtgga gatgctgtgt
      781 gggctcaaga tgaagctgaa gcaacagcga gtgtcatcca tcctccctga gcaccacaag
      841 gacttcaaca gtcagcttgc ccctggggta gatcccagcc ccccgcatag gtccttttgc
      901 tggaaaagga agatggagtg gtgggacgaa tctgaggagt cgttggagga ggagccacgg
      961 aaggtgctcg cccctgagcc tgaggagatc tgggtggcgg agatgctgtg tggcctcaag
     1021 atgaagctga agcgacggcg agtgtcgctc gtgctccctg agcaccacga ggccttcaac
     1081 aggctgcttg aggatcctgt cattaaaaga ttcttggcct gggacaaaga tctgagggtg
     1141 tcggacaagt atctcctggc tatggtcata gcgtatttca gccgggccgg cttcccctcc
     1201 tggcaatacc aacgcattca tttcttcctg gctctctacc tggccaatga catggaggag
     1261 gacgacgagg actccaaaca aaacatcttc cacttcctgt ataggaagaa ccgctctcgc
     1321 atacccttgc tccgtaagcc ttggttccag ttaggccatt ccatgaaccc gagggccagg
     1381 aagaaccgct ctcgcatacc cttgctccgt aagcgtcggt tccagttata ccgttccacg
     1441 aacccgaggg ccaggaagaa ccgctctcgc atacccttgc tccgtaagcg tcggttccag
     1501 ttataccgtt ccatgaactc gagggccagg aagaaccgct ctcagatagt cctgttccag
     1561 aaacgacggt tccacttctt ctgttccatg agctgcaggg cttgggtttc cccagaggag
     1621 ttggaggaga tccaggctta tgacccagag cactgggtgt gggcgcgaga tcgcgctcac
     1681 ctttcctaga gctccaggga ccggggaggc ctgaggtcat cggcctgaga gaagaacacc
     1741 ggacccaggg gagatgtgga ttttcagcgg gaactttatt ccaatgctaa tggcagacac
     1801 caggcaggag gagaggaacc atttgtgcag atcatctaga agaacctgga ccattcttga
     1861 tggagctgaa tacagtgatc acgttgtcct cctaggagca ggggtggggg gaggggggtg
     1921 gggtccttct aggagtcctt ggagaaaagt aagaaaccag gagcgtttcc agttccaccc
     1981 tttcctgcgg caccaccacc ctttttatat tgctgaattc caacctccct ggggcggaac
     2041 ctggaggtcc tgtttcttac ggacttgcag tccaggagga tttgaaggca caatgcaggg
     2101 gctcagattg ggacagaatt cttttgtgaa atatcagtgc cacagattgt aacagatagc
     2161 ttcatgcaca ctctgcattt tattggtttg tatggaaaat gtcggccatt gaattattca
     2221 tagatttatt tcaaatagtt tggaaattgt tgtacttttg aaaacatgct gttcctgtag
     2281 ttttttgatg agagttatag ttgttatata tacataaagc taattttctt ttcattttta
     2341 agagacaatt ctttttatcc taaatatttt attatcttta aatttgtttc tgtattatta
     2401 catgtgctcc tgaagcgagc actcttttta tctatgatac ttccataata atctcttcta
     2461 tttatagcta ttggtagttc cccaccagaa aaaaacataa ttctggtgat agaaattttt
     2521 atttgctgtt taggtttgtg actgaattgt gagaattcag ttgtgatttt taacatgcct
     2581 cagatatata tactaacacg tctaatatat actatctatt ttattggttt attttgaaaa
     2641 acatgggtat agaattattt aaatattatt ttatttattt aaatatttat taaatatatt
     2701 tatttattta aatattatta ctttaaatat tattttaaat attttggaaa tactggtatt
     2761 tttgaataga tgctgtttct ataaagctgt gtgatggata ttataactgt tatatacaca
     2821 tacatataat tttgttttcc tttttaagag aggattcttt tcatcctaaa tcttttacct
     2881 ttcaatcttt gtatctatta ttacacgtgc tgctgaaggg agcatggttt ttatctatga
     2941 tacttagtta acatatatat tacatttata gctatgtagt agttccccta aattcttgta
     3001 aaaataaatt tttatttgat atttcatata tatttgaaat gtgagaattc agatgtaatt
     3061 ttttaccttg ttttggcatg tttgtatgtt actttaaaga ggatgtgtgt tctaaaggag
     3121 gacatgagct gtgtgttttc aagagaacaa tagagtgcgt ctcttgggga aacataataa
     3181 aaatgaactt ttctcacctt cacagcaatt gtga
//
