LOCUS       NM_001382715            3286 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens speedy/RINGO cell cycle regulator family member E21
            (SPDYE21), mRNA.
ACCESSION   NM_001382715
VERSION     NM_001382715.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3286)
  AUTHORS   Hillier,L.W., Fulton,R.S., Fulton,L.A., Graves,T.A., Pepin,K.H.,
            Wagner-McPherson,C., Layman,D., Maas,J., Jaeger,S., Walker,R.,
            Wylie,K., Sekhon,M., Becker,M.C., O'Laughlin,M.D., Schaller,M.E.,
            Fewell,G.A., Delehaunty,K.D., Miner,T.L., Nash,W.E., Cordes,M.,
            Du,H., Sun,H., Edwards,J., Bradshaw-Cordum,H., Ali,J., Andrews,S.,
            Isak,A., Vanbrunt,A., Nguyen,C., Du,F., Lamar,B., Courtney,L.,
            Kalicki,J., Ozersky,P., Bielicki,L., Scott,K., Holmes,A.,
            Harkins,R., Harris,A., Strong,C.M., Hou,S., Tomlinson,C.,
            Dauphin-Kohlberg,S., Kozlowicz-Reilly,A., Leonard,S., Rohlfing,T.,
            Rock,S.M., Tin-Wollam,A.M., Abbott,A., Minx,P., Maupin,R.,
            Strowmatt,C., Latreille,P., Miller,N., Johnson,D., Murray,J.,
            Woessner,J.P., Wendl,M.C., Yang,S.P., Schultz,B.R., Wallis,J.W.,
            Spieth,J., Bieri,T.A., Nelson,J.O., Berkowicz,N., Wohldmann,P.E.,
            Cook,L.L., Hickenbotham,M.T., Eldred,J., Williams,D., Bedell,J.A.,
            Mardis,E.R., Clifton,S.W., Chissoe,S.L., Marra,M.A., Raymond,C.,
            Haugen,E., Gillett,W., Zhou,Y., James,R., Phelps,K., Iadanoto,S.,
            Bubb,K., Simms,E., Levy,R., Clendenning,J., Kaul,R., Kent,W.J.,
            Furey,T.S., Baertsch,R.A., Brent,M.R., Keibler,E., Flicek,P.,
            Bork,P., Suyama,M., Bailey,J.A., Portnoy,M.E., Torrents,D.,
            Chinwalla,A.T., Gish,W.R., Eddy,S.R., McPherson,J.D., Olson,M.V.,
            Eichler,E.E., Green,E.D., Waterston,R.H. and Wilson,R.K.
  TITLE     The DNA sequence of human chromosome 7
  JOURNAL   Nature 424 (6945), 157-164 (2003)
   PUBMED   12853948
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006480.3.
            
            On May 11, 2021 this sequence version replaced NM_001382715.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000424157.4/ ENSP00000498431.1
            RefSeq Select criteria    :: based on manual assertion, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AC006480.3         42427-42548
            123-704             AC006480.3         43778-44359
            705-923             AC006480.3         45304-45522
            924-1154            AC006480.3         46860-47090
            1155-1213           AC006480.3         48121-48179
            1214-1299           AC006480.3         49399-49484
            1300-1693           AC006480.3         51530-51923
            1694-1798           AC006480.3         52046-52150
            1799-3286           AC006480.3         53004-54491
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q11.21"
     gene            1..3286
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /note="speedy/RINGO cell cycle regulator family member
                     E21"
                     /db_xref="GeneID:442572"
                     /db_xref="HGNC:HGNC:51517"
     exon            1..122
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            123..704
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     CDS             545..1753
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /note="Putative WBSCR19-like protein 8; speedy homolog E1
                     pseudogene; speedy/RINGO cell cycle regulator family
                     member E21, pseudogene"
                     /codon_start=1
                     /product="putative speedy protein E21"
                     /protein_id="NP_001369644.1"
                     /db_xref="CCDS:CCDS94109.1"
                     /db_xref="GeneID:442572"
                     /db_xref="HGNC:HGNC:51517"
                     /translation="MDRTETRFRKRGQITGKITTSRQLHPQNEQSPQRSTSGYPLQEV
                     VDDEVLGPSAPGVDPSPPCRSLGWKRKKEWSDESEEEPEKELAPEPEETWVVETLCGL
                     KMKLKQQRVSPILPEHHKDFNSQLAPGVDPSPPHRSFCWKRKREWWDESEESLEEEPR
                     KVLAPEPEEIWVAEMLCGLKMKLKRRRVLLVLPEHHEAFNRLLEDPVIKRFLAWDKDL
                     RVSDKYLLAMVIVYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYGK
                     TRSRIPLLRKRWFQLGRSMNPRARKNRSRIPLLRKRRFQLGRSMNPRARKYRSRIPLV
                     RKRRFQLRRCMNPRARKNRSQIVLFQKLRFQFFCSMSGRAWVSPEELEEIQAYDPEHW
                     VWARDRAHLS"
     exon            705..923
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1154
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1213
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1299
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1693
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1798
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..3286
                     /gene="SPDYE21"
                     /gene_synonym="SPDYE21P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacaatggga cttccacagc aatgggatcg gcttcctctt tcagtgtgtg ccttttctat
       61 gagcgagaga ctcctaggaa agcagcagcc cattaggaaa acgtgtggga actcactcgc
      121 agcctggact ctgaaatggg catgtacaga gacgaagaga ccccaacatg cttcaggctt
      181 tgagtggaga ggacacagcc tctgctggga cagggaacag agggatgtgg agtccctgaa
      241 gatgcttttg gacaatggtc tgaggttggg acagtggcag gagataccat tcacccagga
      301 tctccaggac aagagatcag cctggcagtt acatgtgttt ttttttcaaa ctggttgcca
      361 ggttggcatg aacgatgaca tcagagattc cgaccttcct gattggaggg accggactcc
      421 gtggtgcctg gagatcagtt ggacaacagt atcttctcag agctgttctc cactcctgac
      481 ttctcctagg cttgagaatt gataacatac tcttctggat cctagcagtg tccagaagaa
      541 ggccatggac agaacggaga ctaggttccg taagagggga cagattacgg gaaagatcac
      601 gaccagccgt caactgcacc cccagaatga gcagagtccc cagcggagca cctcggggta
      661 ccccctccag gaggtggtgg atgatgaagt gttgggacca tcagcccctg gggtagatcc
      721 cagcccccca tgtaggtccc ttggctggaa aaggaagaag gagtggtcag atgaatctga
      781 ggaggagccg gagaaggagc tcgcccctga gcctgaggag acctgggtag tggagacgct
      841 gtgtgggctt aagatgaagc tgaagcaaca gcgagtgtca cccatcctcc ctgagcacca
      901 caaggacttc aacagtcagc ttgcccctgg ggtagatccc agccccccgc ataggtcctt
      961 ttgctggaaa aggaagaggg agtggtggga cgaatctgag gagtcgttgg aggaggagcc
     1021 acggaaggtg ctcgcccctg agcctgagga gatctgggtg gcggagatgc tgtgtggcct
     1081 caagatgaag ctgaagcgac ggcgagtgtt gctcgtgctc cctgagcacc acgaggcctt
     1141 caacaggctg cttgaggatc ctgtcattaa aagattcctg gcctgggaca aagatctgag
     1201 ggtgtcggac aagtatctcc tggctatggt catagtgtat ttcagccggg ccggcctccc
     1261 ctcctggcaa taccaacgca ttcatttctt cctggctctc tacctggcca atgacatgga
     1321 ggaggacgac gaggactcca aacaaaacat cttccacttc ctgtatggga agacccgctc
     1381 tcgcataccc ttgctccgta agcgttggtt ccagttaggc cgttccatga acccgagggc
     1441 caggaagaac cgctctcgca tacccttgct ccgtaagcgt cggttccagt taggccgttc
     1501 catgaacccg agggccagga agtaccgctc tcgcataccc ttggtccgta agcgtcggtt
     1561 ccagttacgc cgttgcatga acccgagggc caggaagaac cgctctcaga tagtcctgtt
     1621 ccagaaactt cggttccagt tcttctgttc catgagcggc agggcttggg tttccccgga
     1681 ggagttggag gagatccagg cttatgaccc agagcactgg gtgtgggcac gagatcgcgc
     1741 tcacctttcc tagagctcca gggaccgtgg aggcctgagg tcatcggcct gagagaagaa
     1801 caccggaccc aggggagatg tggattttca gcaggaactt tattccaatg ctaatggcag
     1861 acaccaggaa ggagaagagg aaccatttgt gcagatcatc tagaagaacc tggaccattc
     1921 ttgatggagc tgaatacagt gatcacgtgt cctcctggga gcaggggttg ggggaggggg
     1981 gtggggtcct tctaggagtc cttggagaaa agtaagaaac caggagtgtt tccagttcca
     2041 ccctttcctg cggcaccacc acccttttta tattgctgaa ttccaacctc cctggggcgg
     2101 aacctggagg tgctgtttct tacggacttg gttgccacag tccaggagca tttgaaggca
     2161 caatgcaggg gctcagattg gcacagaatt cttttgtgaa atatcagtgc cacagattgt
     2221 aacagatagc ttcatgcaca ctctgcattt tattggtttg tttggaaaat gttggccatt
     2281 gaattattca tagatttatt tcaaatagtt tggaaattgt tgtacttttg aaaacatgct
     2341 gttcctgtag ttttttgatg agagttatag ttgttatata tacataaaga taattttctt
     2401 ttcattttta agagacaatt ctttttatcc taaatatttt attatcttta aatttttttc
     2461 tgtattatta tatgtgctcc tgaagcgagc actcttttta tctatgatac ttccataata
     2521 atctcttcta tttatagcta ttggtagttc cccaccagaa aaaaacataa ttctggtgat
     2581 agaaattttt atttgctgtt taggtttgtg actgaattgt gagaattcag ttgtgatttt
     2641 taacatgtct cagatatata tactaacacg tctaatatat actatctatt ttattggttt
     2701 attttgaaaa acatgggtat agaattattt aaatattatt ttatttattt aaatatttat
     2761 taaatatatt tatttattta aatattatta ttactttaaa tattatttta aatattttgg
     2821 aaatactggt atttttgaat agatgctgtt tctataaagc tgtgtgatgg gtattataac
     2881 tgttatatac acatacatat aattttgttt tcctttttaa gagaggattc ttttcatcct
     2941 aaatctttta cctttcaatc tttgtatcta ttattacacg tgctgctgaa gggagcatgt
     3001 ttttatctat gatacttagt taacatatat attacattta tagctatgta gtagttcccc
     3061 taaattcttg taaaaataaa tttttatttg atatttcata tatatttgaa atgtgagaat
     3121 tcagatgtaa ttttttacct tgttttggca tgtttgtata ttactttaaa gaggatgtgt
     3181 gttctaaagg aggacatgag ctgtgtgttt tcaagagaac aatagagtgc gtctcttggg
     3241 gaaacataat aaaaatgaac ttttctcacc ttcacagcaa ttgtga
//
