LOCUS       NM_001353486            3904 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens spermatogenesis associated 6 like (SPATA6L),
            transcript variant 3, mRNA.
ACCESSION   NM_001353486 XM_006716799
VERSION     NM_001353486.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Wojczynski,M.K., Li,M., Bielak,L.F., Kerr,K.F., Reiner,A.P.,
            Wong,N.D., Yanek,L.R., Qu,L., White,C.C., Lange,L.A.,
            Ferguson,J.F., He,J., Young,T., Mosley,T.H., Smith,J.A., Kral,B.G.,
            Guo,X., Wong,Q., Ganesh,S.K., Heckbert,S.R., Griswold,M.E.,
            O'Leary,D.H., Budoff,M., Carr,J.J., Taylor,H.A. Jr., Bluemke,D.A.,
            Demissie,S., Hwang,S.J., Paltoo,D.N., Polak,J.F., Psaty,B.M.,
            Becker,D.M., Province,M.A., Post,W.S., O'Donnell,C.J., Wilson,J.G.,
            Harris,T.B., Kavousi,M., Cupples,L.A., Rotter,J.I., Fornage,M.,
            Becker,L.C., Peyser,P.A., Borecki,I.B. and Reilly,M.P.
  TITLE     Genetics of coronary artery calcification among African Americans,
            a meta-analysis
  JOURNAL   BMC Med Genet 14, 75 (2013)
   PUBMED   23870195
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3904)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136231.12.
            
            On Jun 2, 2019 this sequence version replaced NM_001353486.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.172412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN04284274 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000682582.1/ ENSP00000506787.1
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-269               AL136231.12        105142-105410       c
            270-407             AL136231.12        100829-100966       c
            408-456             AL136231.12        94971-95019         c
            457-581             AL136231.12        74205-74329         c
            582-659             AL136231.12        68021-68098         c
            660-899             AL136231.12        64257-64496         c
            900-1002            AL136231.12        61338-61440         c
            1003-1037           AL136231.12        57794-57828         c
            1038-1225           AL136231.12        56853-57040         c
            1226-1319           AL136231.12        44277-44370         c
            1320-1410           AL136231.12        43109-43199         c
            1411-3904           AL136231.12        37246-39739         c
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p24.2-p24.1"
     gene            1..3904
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /note="spermatogenesis associated 6 like"
                     /db_xref="GeneID:55064"
                     /db_xref="HGNC:HGNC:25472"
     exon            1..269
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..1409
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /note="isoform b is encoded by transcript variant 3;
                     spermatogenesis associated 6-like protein"
                     /codon_start=1
                     /product="spermatogenesis associated 6-like protein
                     isoform b"
                     /protein_id="NP_001340415.1"
                     /db_xref="CCDS:CCDS6453.1"
                     /db_xref="GeneID:55064"
                     /db_xref="HGNC:HGNC:25472"
                     /translation="MPLEVVVELQIRAISCPGVFLPGKQDVYLGVYLMNQYLETNSFP
                     SAFPIMIQESMRFEKVFESAVDPGAVVDLLEMWDELAYYEENTRDFLFPEPKLTPSHP
                     RRCREVLMKTALGFPGIAPKIEFSTRTAIRECVFLHRNRFLEERHESRRPLSTSHEPI
                     FPLNTIKMKLKENNLNRLPKGMQARAPSQYSTRHFFQDQPAQLNLGNNFKISGGSKPP
                     FVVRHVDSAKPFGENISEHHLRRSRRKSKFSDFPFPTRRASSLDSLAANVKVIKEPDE
                     RIVLRSDSSSCLDSSQFGKSSSSKQGDADFHGKASFATYQHSTSPGPLDQPLLRERFH
                     PGSQSTWKNIHERVCSLLTSHRAQLHQNKEDSTSEVNYIIERPSYPLKKYSLHEQRYF
                     "
     exon            270..407
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            408..456
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            457..581
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            582..659
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            660..899
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1002
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1037
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1225
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1319
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1410
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..3904
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3885..3890
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /note="hexamer: ATTAAA"
     polyA_site      3904
                     /gene="SPATA6L"
                     /gene_synonym="bA6J24.2; C9orf68"
                     /note="major polyA site"
ORIGIN      
        1 aacgccacgc ttccgccttc tggaagcctg cactccagct tcgagtgtga gagacccgtc
       61 ccggtgggag ggacctgggc tgggggggac ggtaggggaa caagggcgtg ggactgggga
      121 agcttctggg aacatttgct ctaggtattc agctaaacta agaaaaattg gtccaaggct
      181 cggcacaaaa ggatcttctc attccagtcc tttcgcccac gcagggaacg atgcctctgg
      241 aggtggtggt ggagctgcag atccgggcga tttcttgccc aggagtgttc ctgcctggca
      301 aacaagatgt gtacctcggg gtctacctca tgaatcagta cctggagacc aacagctttc
      361 cctctgcgtt ccccattatg attcaggaga gcatgagatt tgaaaaggta tttgaaagtg
      421 cagtagatcc tggagctgta gtagaccttt tggaaatgtg ggatgagttg gcctactacg
      481 aagaaaacac acgagatttt cttttcccag agcccaagct gacaccttcg caccctagga
      541 ggtgtaggga ggtgctcatg aagacggctc tgggttttcc aggcattgct cccaaaatag
      601 agttttctac aaggacagcc atcagagaat gtgtgtttct gcatagaaac agatttcttg
      661 aagaaagaca tgagtcacgg aggcctttat ctacatcaca tgaaccaata tttcccttaa
      721 atactataaa gatgaaacta aaggagaata atctcaacag actgcccaaa ggcatgcaag
      781 cccgggcgcc ctctcaatat tctaccaggc atttcttcca ggaccagcca gctcagttga
      841 accttggaaa taatttcaaa atctctggag gaagcaagcc tccatttgtt gttagacacg
      901 tggacagtgc aaagcccttt ggtgagaata tttcagagca tcatttgagg aggtctagaa
      961 gaaaatctaa gttttcagac tttccgtttc caacgagaag agcttcttct cttgacagcc
     1021 ttgcagctaa cgtaaaggtt atcaaagagc cagatgaacg gattgtttta aggagtgact
     1081 catcatcatg tttagattca agtcagtttg gaaagtcttc atccagtaaa caaggggatg
     1141 ctgatttcca cgggaaagct tcatttgcca cctaccagca ttccacctct cctggcccct
     1201 tggatcagcc ccttctcaga gaaaggttcc atcctggttc tcagtccaca tggaagaata
     1261 tccatgagag ggtatgcagt cttctgacat cccacagagc acagctgcac caaaacaagg
     1321 aagattctac ctctgaagta aattatatca ttgaaagacc aagctaccct ctgaagaaat
     1381 actcactgca tgaacagaga tatttttaag gggaaattaa tgaaagctta aggagaatca
     1441 tgaagagctc actcactgag acaattgaag catccttaaa gaaatgaaca ctttttgttg
     1501 tctgtgttga gtcactgatg tctaatcccc tttaaaccaa accctgtact cagtcttttg
     1561 tgcccaggta agagttgttg attaaagtgt ttgctgtttg ggggctaaca ttttcttgtc
     1621 aagctggaaa atttgtgttt ttgcatgttt gttttgaaca tgaaagagaa agcgctgtag
     1681 ttgggtggca ggtgcttatc tgaacacttc ccctctctct ctctctggct ctctctggct
     1741 ctctctgtct ctctctctca aattaattat atatgagcta gaggaagttg ctattcacag
     1801 gaataacctg ataaatcctc caggaaagac tatcaacctg actttctctt ttcggtagat
     1861 ccgtttttgt tgttgtttgt ttatttctta gtgttaggct tgatttacgt gaagtccact
     1921 aaaaaccttg gaaaagagag cattacgtct gggtagttca gatcttgttt tagatgttga
     1981 atgtctgtga taaatttgta agaggaggct ggctcctctg gagcgtagtt taaactgctc
     2041 cttctgtttc ctactccttc gttccagcaa ttctttgtaa atttagatga ggaacaaaac
     2101 cttcctcaaa tatttctcca aaagaactac acattaagta aataggttct acagatagga
     2161 ctgccaatgc caggttttaa agttagttag gaaggtgcat ctatgaaatg cttacacagt
     2221 gtgagggagc aggaatagga aggggctggg ataaagggag actagaggca catttgtctt
     2281 cattgataca gacccagaga agaggggcct gaaaatggaa acttatttcc ctccttcata
     2341 gtgtaagcat agcattttcc tctaccagcc ctactatagt gtgaatgttt gtgtcccctc
     2401 aacatttgta tgttgaaatc ctaacctcta aggaaatggg gccttttggg aggtgatgag
     2461 gttgtgaggg tggacccctc ataaatgaga ttagtgccct ataaataggc tcaagggagc
     2521 tcgtttgccc cttccactgg cgaggagaca gcgagaaggc gccatctctg acccaggaag
     2581 agggccctca ccagattctg catctgccaa cattctgatc ttggacttcc cagcttccag
     2641 aactgtgaga aatgaattcc tgtagtttgt aagctaccca gtttatgaca ttttgttata
     2701 gcagcctgaa tagagtaaga cactacccta aaacttgttc agtttttaga agattcagtg
     2761 agagccaagt tttcttttct cactgtaatc atagggattg gttcattagg taaattaaga
     2821 aaatgaaatt aaaaattaaa acagaaaagg aactccaaaa acaaaaacaa caaaacaaaa
     2881 ttcatttatc ctcttcttag aatttcagcc aaataaaggt atatccaagt tgaacctccc
     2941 aatctaaaaa tctgaaatct gaaatgctcc aaaatccaaa actttttgag caccaatata
     3001 acaccataag tgaaaaattc cacatctgac tgcatgtggc agggtgcagt caaatgcatt
     3061 cgaaactttg tttcatgctc caaattattt aaaatcatgt ataaaattac cttcaggcta
     3121 cctgtataaa gtgtatataa aacgtaaatg aatttcgtgt ttagacttgg gtcctatccc
     3181 ctatcctgaa gatacttcat tgtgtttatg taaatattcc aaaatacaaa aacaaaaacc
     3241 aaaacccaag tttaaaatac ttctggtcag tcccaagcac tgaagataag ggagactcaa
     3301 cctgtatcac aaccagcatt ccaccttggc aaggccaaca gcaagcttaa attacatatg
     3361 ctaatatgtt ctcagtctct ctgaaactat ggttgtcaat ttgttgtttt gatgttacct
     3421 ctaagtagtc atcaaaagta agaaaatatt gtgttacatt aaggttacgc tataagtctc
     3481 aggagagggc tgcttacgta agcagctaaa ggaaagcagc actaatgaat tggtatccca
     3541 tttcagttat tgttaaaata tacaccatga cattcaatat tcagtgtttt ttgaaatggt
     3601 ttaagcataa ctctttaata agatcttaaa tgcccattct tatttaaagt catttttggt
     3661 tttcacacta aattacgctt tttttccctt tacttttgca tctattaact ctattcctta
     3721 aattattatt atttttactt ttgtttctca aggagttatc tcaattttga ggaatcatgc
     3781 tggggcaagg attgcagttg aagtattttg cttttggagt gtataatagt atgaataatt
     3841 ttgtgatgtt ttggggtttg gattactttg ggaagatctg tgtcattaaa catcataaaa
     3901 agaa
//
