LOCUS       NM_152343               1266 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens spermatogenesis associated 32 (SPATA32), mRNA.
ACCESSION   NM_152343
VERSION     NM_152343.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1266)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1266)
  AUTHORS   Casabonne,D., Reina,O., Benavente,Y., Becker,N., Maynadie,M.,
            Foretova,L., Cocco,P., Gonzalez-Neira,A., Nieters,A., Boffetta,P.,
            Middeldorp,J.M. and de Sanjose,S.
  TITLE     Single nucleotide polymorphisms of matrix metalloproteinase 9
            (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus
            in chronic lymphocytic leukemia: results from the European
            case-control study EpiLymph
  JOURNAL   Haematologica 96 (2), 323-327 (2011)
   PUBMED   21048031
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
REFERENCE   3  (bases 1 to 1266)
  AUTHORS   Lee,K.F., Tam,Y.T., Zuo,Y., Cheong,A.W., Pang,R.T., Lee,N.P.,
            Shum,C.K., Tam,P.C., Cheung,A.N., Yang,Z.M., Yeung,W.S. and
            Luk,J.M.
  TITLE     Characterization of an acrosome protein VAD1.2/AEP2 which is
            differentially expressed in spermatogenesis
  JOURNAL   Mol Hum Reprod 14 (8), 465-474 (2008)
   PUBMED   18621766
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP369808.1, BP370574.1 and BC028124.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152343.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC028124.1, AK058143.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2144333 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000331780.5/ ENSP00000331532.4
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 BP369808.1         20-25
            7-27                BP370574.1         4-24
            28-501              BC028124.1         1-474
            502-533             BP369808.1         519-550
            534-1266            BC028124.1         507-1239
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.31"
     gene            1..1266
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /note="spermatogenesis associated 32"
                     /db_xref="GeneID:124783"
                     /db_xref="HGNC:HGNC:26349"
     exon            1..91
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1233
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /note="testis-expressed sequence 34 protein; testis
                     expressed 34; acrosome expressed 2; CTD-2020K17.4;
                     testis-expressed protein 34"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 32"
                     /protein_id="NP_689556.2"
                     /db_xref="CCDS:CCDS32669.1"
                     /db_xref="GeneID:124783"
                     /db_xref="HGNC:HGNC:26349"
                     /translation="MGVTGAHGFPCCGKGSVEVAEMRDDLSQHQIQEEQELEADMLEQ
                     KPQLQVDLDLDPDPDPDPELEIGQVPALLESELYPALKLEAELDTEANSNEESDFEEP
                     MQLVCKIESVHSNMGLPTPQTFRPWSLNSNCRSFTEENHVSACHHSISAQTSKHLFWA
                     NKLIQASEHSLQRAINMQLNNGSAGQPIRSPLREAIPTNALCSEEQLQIPDAHSAPPT
                     TSSQAPSPLLSSDLPPPIDLTELITFASSLAMASSSRMDLPSLEHMMKAPPQEALEPS
                     TEPLLTTVEEREPENHAETLPEKPREARAPLKSWSQEDKNFAQSYFDFSKPGIKRATI
                     KGQIQLLQPPATSPLLQGSKEDSVPPGKEKENPLLVKIHFKLSAPTIPEK"
     exon            92..146
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /inference="alignment:Splign:2.1.0"
     exon            147..186
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /inference="alignment:Splign:2.1.0"
     exon            187..1145
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1266
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1246..1251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /note="hexamer: AATAAA"
     polyA_site      1266
                     /gene="SPATA32"
                     /gene_synonym="AEP2; C17orf46; TEX34; VAD1.2"
                     /note="major polyA site"
ORIGIN      
        1 agccaaagag cacactggag gcggagaggc agcatccacc agcccgctcc ccgcctccag
       61 gacagagcct cggtctgcat gggggtgaca ggtgcccatg gatttccatg ctgcggcaaa
      121 gggtcagtgg aggttgcaga gatgcgagat gacttaagtc aacaccagat acaagaggaa
      181 caggagctgg aggcagacat gctagagcag aagccccaac tccaagtgga cctggacctg
      241 gacccagacc cagacccaga cccagaactg gagatcggac aggtgccggc tttactggag
      301 tcagagctat acccagccct caagcttgaa gctgagctgg acacggaagc caactcgaac
      361 gaggagtctg actttgaaga acccatgcag ctggtatgca agatagagtc cgtccactcc
      421 aacatggggc tgcccacgcc acagaccttc agaccgtgga gtctgaattc aaactgccgg
      481 agtttcacgg aggagaacca cgtgtctgcc tgccatcact ccatcagtgc gcagacctcc
      541 aagcacctct tctgggcaaa caagctcatc caggcctcag agcacagcct gcagcgggcc
      601 atcaacatgc agctcaacaa tggcagcgca ggccagccca tcagatcccc gctccgggag
      661 gccatcccca ccaacgccct gtgctccgag gagcagctcc agatccctga tgcccactca
      721 gctcctccaa ccacaagctc ccaggcacca agccccctcc tgtcctcaga tctcccgcca
      781 cccattgacc tgacagagct aatcaccttt gcatcttccc tggccatggc ctcctccagc
      841 aggatggacc tgcccagttt ggaacacatg atgaaagctc caccccagga ggctctggag
      901 ccttccacag agcccctcct gaccactgtg gaggagcgag agccagaaaa tcacgcagag
      961 accctgccag agaaaccacg cgaagccaga gcaccactga aatcttggag tcaggaagac
     1021 aagaacttcg ctcaatctta ctttgacttc agcaagccgg ggatcaagag ggccaccatc
     1081 aaagggcaaa tccagcttct ccagccacca gccacgtccc ctctgctgca gggaagcaag
     1141 gaagactcag tgccgccagg aaaagagaaa gagaatccat tattggtgaa aatccatttt
     1201 aagctgtcag cccccacaat cccagagaaa tgactagaca gaaccaataa agcctccagt
     1261 gctggc
//
