LOCUS       NM_001309427             967 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens SPATA31 subfamily F member 3 (SPATA31F3), transcript
            variant 2, mRNA.
ACCESSION   NM_001309427
VERSION     NM_001309427.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB042441.1, AL355377.25 and AI125404.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001309427.1.
            
            Transcript Variant: This variant (2) uses two alternate in-frame
            splice sites in the 3' coding region, compared to variant 1,
            resulting in an isoform (b) that is shorter than isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB042441.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340783.11/ ENSP00000489571.1
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               DB042441.1         16-160
            146-164             AL355377.25        20359-20377         c
            165-521             DB042441.1         181-537
            522-967             AI125404.1         1-446               c
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p13.3"
     gene            1..967
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /note="SPATA31 subfamily F member 3"
                     /db_xref="GeneID:100129969"
                     /db_xref="HGNC:HGNC:42673"
     exon            1..186
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..669
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /note="isoform b is encoded by transcript variant 2;
                     transmembrane protein C9orf144B pseudogene; putative
                     family with sequence similarity 205, member C protein;
                     family with sequence similarity 205, member C, pseudogene;
                     protein FAM205CP; FAM205C pseudogene; family with sequence
                     similarity 205 member C; protein SPATA31F3"
                     /codon_start=1
                     /product="protein SPATA31F3 isoform b"
                     /protein_id="NP_001296356.1"
                     /db_xref="CCDS:CCDS83359.1"
                     /db_xref="GeneID:100129969"
                     /db_xref="HGNC:HGNC:42673"
                     /translation="MLSPTFVLWDVGYPLYTYGSICIIALIIWQVKKSCQKLSLVPNR
                     SCCRCHRRVQQKSGDRTSRARRTSQEEAEKLWKLLFLMKSQGWLPQEGSVRRILCADP
                     CCQICNVMALEIKQLLAAPEVGLDNKMKLFLHWINPEMKDRRHEESILLSKAETVTQD
                     RTKNIEKSPTVTKDHVWGATTQKTTEDPEAQPPSTEEEGLIFCDAPSA"
     exon            187..232
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /inference="alignment:Splign:2.1.0"
     exon            233..293
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /inference="alignment:Splign:2.1.0"
     exon            294..400
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /inference="alignment:Splign:2.1.0"
     exon            401..967
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      943..948
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /note="hexamer: AATATA"
     polyA_site      967
                     /gene="SPATA31F3"
                     /gene_synonym="FAM205C; FAM205CP"
                     /note="major polyA site"
ORIGIN      
        1 agtgaaagac tagggagagg gatggctagt gaggtttaga tcatgttgag ccctaccttt
       61 gttttgtggg atgttggata tcccttatac acctatggat ccatctgcat tattgcatta
      121 attatttggc aagtgaaaaa gagctgccaa aaattaagct tggtacctaa caggagctgt
      181 tgccggtgtc accgaagagt ccaacaaaag tctggagata gaacatcaag agctaggaga
      241 acttcacagg aagaagccga gaagttgtgg aagctgctgt ttctcatgaa aagccagggc
      301 tggcttcctc aggaaggaag tgtgcggcga atcctgtgtg cagacccctg ctgccaaatc
      361 tgcaatgtta tggctctgga gattaagcaa ttgctggcag ctccagaagt tggcttggat
      421 aacaagatga agctgtttct gcactggatt aaccctgaaa tgaaagatcg aaggcatgag
      481 gaatccattc tcctttctaa ggctgagaca gtgacccaag acaggacaaa aaacattgag
      541 aagagtccaa ctgtcaccaa agatcatgtg tggggagcta caacacagaa gacaacagag
      601 gaccctgagg ctcagcctcc ttctactgag gaggaaggcc tgatcttctg tgatgccccc
      661 agtgcctaaa taatctgctc tagcaacact cccttcagtc cagccaatcc tgggtcctgt
      721 gccactccta caaatgctcc aaactctgtc ctcaaatgac ttgtgccact caaccaggaa
      781 atctatccca ggtctaactc acctcagcag aaggcactgt tttatgcaag aatacccatc
      841 acaagaaaaa ggagttcata ggttcctgaa cctctgcaat cccctgaaaa aggctttcat
      901 tgccatttcc attaacatgc aggtgaagca gggcattctc caaatatact ttgtaccttt
      961 aagcaaa
//
