LOCUS       NM_152339               2331 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens spermatogenesis associated 2 like (SPATA2L), mRNA.
ACCESSION   NM_152339
VERSION     NM_152339.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2331)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 2331)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 2331)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 2331)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010538.9.
            
            On Nov 23, 2018 this sequence version replaced NM_152339.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039608.1, SRR3476690.864404.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000289805.10/ ENSP00000289805.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AC010538.9         39969-40046
            79-382              AC010538.9         40441-40744
            383-2331            AC010538.9         43369-45317
FEATURES             Location/Qualifiers
     source          1..2331
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q24.3"
     gene            1..2331
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /note="spermatogenesis associated 2 like"
                     /db_xref="GeneID:124044"
                     /db_xref="HGNC:HGNC:28393"
     exon            1..78
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /inference="alignment:Splign:2.1.0"
     exon            79..382
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1354
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /note="SPATA2-like protein"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 2-like
                     protein"
                     /protein_id="NP_689552.2"
                     /db_xref="CCDS:CCDS10985.1"
                     /db_xref="GeneID:124044"
                     /db_xref="HGNC:HGNC:28393"
                     /translation="MGSSSLSEDYRQCLERELRRGRAGVCGDPSLRAVLWQILVEDFD
                     LHGALQDDALALLTDGLWGRADLAPALRGLARAFELLELAAVHLYLLPWRKEFTTIKT
                     FSGGYVHVLKGVLSDDLLLKSFQKMGYVRRDSHRLMVTALPPACQLVQVALGCFALRL
                     ECEILGEVLAQLGTSVLPAEELLQARRASGDVASCVAWLQQRLAQDEEPPPLPPRGSP
                     AAYRAPLDLYRDLQEDEGSEDASLYGEPSPGPDSPPAELAYRPPLWEQSAKLWGTGGR
                     AWEPPAEELPQASSPPYGALEEGLEPEPSAFSFLSLRRELSRPGDLATPESSAAASPR
                     RIRAEGVPASAYRSVSEPPGYQAHSCLSPGALPTLCCDTCRQLHAAHCAALPACRPGH
                     SLRVLLGDAQRRLWLQRAQMDTLLYNSPGARP"
     exon            383..2331
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2312..2317
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /note="hexamer: ATTAAA"
     polyA_site      2331
                     /gene="SPATA2L"
                     /gene_synonym="C16orf76; tamo"
                     /note="major polyA site"
ORIGIN      
        1 gactcccggc ggaagcgcgc ggcgcgcggg gaggcccgaa ctgatccgcg gcggccggag
       61 accgctgggg acagacagga tgggcagcag ctcgctgtcc gaggactacc gccagtgcct
      121 ggagcgcgag ctgcgacggg gccgcgcggg cgtgtgcggg gacccctcgc tgcgcgcggt
      181 gctctggcag atcctggtgg aggacttcga cctgcacggg gcgctgcagg acgacgcgct
      241 ggctctgctc accgacgggc tgtggggccg cgccgacctg gcgcccgcgc tacgcggcct
      301 ggctcgcgcc ttcgagcttc tggagctcgc cgcggtgcac ctgtacctgc tgccctggag
      361 gaaggagttc accaccatca agaccttctc tgggggctac gtgcacgtgc tgaagggtgt
      421 gctctcagac gacctcctcc tgaagagctt ccagaagatg ggctacgtac gcagagacag
      481 ccatcggctc atggtgaccg ccctgccccc cgcctgccag ctggtgcagg tggccctggg
      541 ctgcttcgcc ctccggctgg agtgtgagat cctgggtgag gtgctggccc agctgggcac
      601 cagtgtgctg ccagctgagg agctgctgca ggcacggcgt gccagcgggg acgtggcctc
      661 ctgtgtggcc tggctgcagc agcggctggc ccaggatgag gagccgccac ccctgccccc
      721 ccgaggctcc cctgctgctt acagggcccc actggactta taccgggact tgcaggaaga
      781 cgaggggtcg gaggacgcca gcctgtatgg ggagccgtca ccaggccctg actcgccccc
      841 ggcggagctg gcctacaggc caccactctg ggagcagagt gccaaactgt ggggcactgg
      901 gggccgggcc tgggagcccc cagctgagga gctgccgcag gccagcagcc caccatatgg
      961 ggccttggag gaggggctgg aacctgaacc ttccgccttc tccttcctct ctctgcgccg
     1021 tgagctgagt aggcctgggg acctggccac ccctgaaagc tctgcagcgg ccagcccgag
     1081 gcgtattcgg gcagaggggg taccagcctc agcctatagg tctgtctcgg agcccccagg
     1141 ctaccaggca cacagctgcc tgtcccctgg cgccctgccc accctctgct gcgacacctg
     1201 tcgccagctg catgctgccc actgtgcagc cctgcccgcc tgccgtccag gccactcgct
     1261 gcgtgtgctg cttggcgacg cccagcggcg cttgtggcta cagcgtgcac agatggacac
     1321 tctgctctac aacagccccg gggcccggcc ctaggccagc tgggccccag gtcaagggct
     1381 cttgggagac agctcccgtg gtgcttctct ttgctgggga ggggtctggg cctctggttg
     1441 ccttgtccct gggggagtcc tgggcacagc agggggttgg agagtccagg ccaacccttg
     1501 ctggaggtgg gactctctgt atatggaagg ctccaagggc agcaggccta agccggccag
     1561 caggagcctt tccacatttc cccaccctcg gaacccagac gcatgcccac atgtgctggg
     1621 tagaggggtc cagcctgttc cagccagtgc ctgaacctgt ccctgagaag gaccctgtgc
     1681 cccaaggccc gtggctcctg gcctgctccc tgcagtacgg agtacggggc tcaggacttg
     1741 ggggtcctcc acgtgtccca gggattctcc acacgagtgt cctcaagggc ctgttggtga
     1801 caccgagctc cccccacccc aagctctgct ggagccaatc tgcggggctc tgccgggtgc
     1861 acggctgacc tggcttcggg gacgccggcc ctccccttgg gtgtcacagc agctgggccc
     1921 acagacagga aatgacctga cctcaaacca gatgtggagg tgcacgagag gcgcaggaac
     1981 gggcagtggc tgacagctgg gaaggccctg agcgtcactg ctgctgggcg gaagggcctg
     2041 tggacagccc gcccaggcgg cggggtcttg gtgggtccag tggtaatggt gcccctcccc
     2101 tccattccct gtgggtgcag cccacaggct ggcgaggagg tgcctctgcc ctaccctcgg
     2161 gtctggcgag ggagagggca gggtgcatcc actgtgacag cccctctggg cccacaactc
     2221 cctgaccctg gaagctgagc ctgctttcct gaccctccgc cccaccccct cctccccaga
     2281 acactcagag ggacggtcaa catcagagca cattaaacgc tggtgaaacc a
//
