LOCUS       NM_080608                742 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens spermatogenesis associated 25 (SPATA25), mRNA.
ACCESSION   NM_080608
VERSION     NM_080608.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 742)
  AUTHORS   Zhou,Y., Qin,D., Tang,A., Zhou,D., Qin,J., Yan,B., Diao,R.,
            Jiang,Z., Cai,Z. and Gui,Y.
  TITLE     Developmental expression pattern of a novel gene, TSG23/Tsg23,
            suggests a role in spermatogenesis
  JOURNAL   Mol Hum Reprod 15 (4), 223-230 (2009)
   PUBMED   19240080
  REMARK    GeneRIF: study identified a novel gene, TSG23/Tsg23, which is
            developmentally & highly expressed in testis; data suggest that
            TSG23/Tsg23 is involved in human and mouse spermatogenesis
REFERENCE   3  (bases 1 to 742)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL008726.3 and BC039607.1.
            
            On Jun 2, 2019 this sequence version replaced NM_080608.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039607.1, BG720358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372519.4/ ENSP00000361597.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AL008726.3         59996-60018         c
            24-742              BC039607.1         1-719
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.12"
     gene            1..742
                     /gene="SPATA25"
                     /gene_synonym="C20orf165; dJ337O18.8; TSG23"
                     /note="spermatogenesis associated 25"
                     /db_xref="GeneID:128497"
                     /db_xref="HGNC:HGNC:16158"
                     /db_xref="MIM:618936"
     exon            1..87
                     /gene="SPATA25"
                     /gene_synonym="C20orf165; dJ337O18.8; TSG23"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..716
                     /gene="SPATA25"
                     /gene_synonym="C20orf165; dJ337O18.8; TSG23"
                     /note="testis-specific gene 23 protein"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 25"
                     /protein_id="NP_542175.1"
                     /db_xref="CCDS:CCDS13383.1"
                     /db_xref="GeneID:128497"
                     /db_xref="HGNC:HGNC:16158"
                     /db_xref="MIM:618936"
                     /translation="MSYFRTPQTHPGPLPSGQGGAASPGLSLGLCSPVEPVVVASGGT
                     GPLSQKAEQVAPAAQAWGPALAMPQARGCPGGTSWETLRKEYSRNCHKFPHVRQLESL
                     GWDNGYSRSRAPDLGGPSRPRPLMLCGLSPRVLPVPSEAVGKEASSQPDICILTLAMM
                     IAGIPTVPVPGVREEDLIWAAQAFMMAHPEPEGAVEGARWEQAHAHTASGKMPLVRSK
                     RGQPPGSCL"
     exon            88..742
                     /gene="SPATA25"
                     /gene_synonym="C20orf165; dJ337O18.8; TSG23"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      742
                     /gene="SPATA25"
                     /gene_synonym="C20orf165; dJ337O18.8; TSG23"
                     /note="major polyA site"
ORIGIN      
        1 attccctcac aaaccggggc tttggggaag ccatgtccta cttcaggact ccacaaactc
       61 atccaggtcc tctgccttcc ggccaaggtg gggctgcttc tccaggcttg tcccttggcc
      121 tctgtagtcc tgtagagcca gtggtggtgg cctctggtgg aacaggccca ctgagccaga
      181 aagctgagca ggtggcacct gctgcccagg cctggggccc agccctggca atgccacaag
      241 ccaggggctg ccctgggggg actagctggg agacactacg gaaggaatac agccgaaact
      301 gccacaaatt cccgcatgtg aggcagctgg agagcttggg ctgggacaat ggctactcca
      361 gaagcagagc ccctgacctg ggtggcccca gcaggcctag gcccctgatg ctgtgtgggc
      421 tgtcaccacg ggttctaccg gtaccctctg aggcagtggg gaaggaggcc agctcccagc
      481 ctgatatctg catcctcacc ctcgccatga tgatcgctgg catccccacc gtgcccgtcc
      541 caggagttcg ggaagaggac ctgatctggg ccgctcaagc tttcatgatg gcccatccgg
      601 agccagaggg tgctgtggag ggggcgcggt gggagcaggc acatgcccac acagcctctg
      661 ggaagatgcc cctagtgaga tctaaaaggg gccagcctcc tggctcctgc ttgtagatgg
      721 atgaaatagc accagatatg ta
//
