LOCUS       NM_198546               2015 bp    mRNA    linear   PRI 02-JUN-2024
DEFINITION  Homo sapiens spermatogenesis associated 21 (SPATA21), transcript
            variant 1, mRNA.
ACCESSION   NM_198546 XM_351235 XM_351236
VERSION     NM_198546.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2015)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY327405.1.
            
            On or before Dec 17, 2003 this sequence version replaced
            XM_351235.1, XM_351236.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY327405.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA1968968,
                                           SAMEA2142680 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000335496.5/ ENSP00000335612.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.13"
     gene            1..2015
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /note="spermatogenesis associated 21"
                     /db_xref="GeneID:374955"
                     /db_xref="HGNC:HGNC:28026"
     exon            1..297
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            298..432
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            433..517
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     CDS             484..1893
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     spermatogenesis-associated protein 21"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 21 isoform 1"
                     /protein_id="NP_940948.1"
                     /db_xref="CCDS:CCDS172.1"
                     /db_xref="GeneID:374955"
                     /db_xref="HGNC:HGNC:28026"
                     /translation="MDNRNTQMYTEEEKTVNPFLPSTPGPKKAKGGGEAVETHPAPGP
                     LPPPEVRDIGERREPDRAQQQPQKPAVAAGTQSLGNFRQGFMKCLLEVEKMEASHRRA
                     SKARSQTAQKSPRTLTPVPTSAPSLPQTPASVPASGPSWARLPAPGPEPAPMGAPVPT
                     SMPCPVLLGPALDLGWRRMELLHQSSERTLSYAKARQEPEEQSLQKLYQNREKSEEQL
                     TLKQEEAFRSYFEIFNGPGEVDAQSLKNILLLMGFSVTLAQVEDALMSADVNGDGRVD
                     FKDFLAVMTDTRRFFCSVEQNALSDMAPHNPHTLLFEILSLLVEMLALPEAVLEEITN
                     YYQKKLKEGTCKAQEMEAAVGRLRLQKLPYNPQQEESSEVPERKVLSILSRLKQQNYA
                     PNLQSPYAQVPCILLCPQLDKKMVRRQPSNHYALDQCTPPGLDPDIRSPFFQSGSQGN
                     REHNSDSRKWLSSVPARTH"
     exon            518..578
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            579..627
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            628..1070
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1156
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1294
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1366
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1484
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1657
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1835
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..2015
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1996..2001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /note="hexamer: AATAAA"
     polyA_site      2015
                     /gene="SPATA21"
                     /gene_synonym="spergen-2; spergen2"
                     /note="major polyA site"
ORIGIN      
        1 actgaaccag tgacaagctg ggggaaatga cactgtccag tagttggagg tcacacagcc
       61 ccttgcctta ttctcaaacc ctaaccacat ggctggatat tcctgaaatg cattcctaaa
      121 cctctgctgc tgagaataat tggacctgcc atctattccc agtttaactg ccctgtatac
      181 caaacaaatc caattcaagc caacaggcaa agtataggct cagacagagc ccatcctatg
      241 tgcaaggcgg tgagcagggg tggaaaatct cactgtgact catccagctg atttctgggc
      301 tgaacccaga cttcacaggg ctgttaggag aatactgttt acaaaggttt ccagcacatg
      361 gaaggttcct ccgtggatgc tggcgggcct gccatgattt aaagtggaag aagcaccatc
      421 aagatcttca aggagcacac taggtgatgc ccctcacttg gcacccgtgt tggcgctggc
      481 atcatggaca atagaaacac ccagatgtac acggaggagg aaaagacagt caaccccttc
      541 ctgccatcca cgcctggacc taaaaaagca aaaggagggg gtgaggctgt ggagacccac
      601 ccagcaccgg ggcctcttcc tccaccagag gtgagggaca ttggagagag gcgggagcca
      661 gaccgtgcgc agcagcagcc tcagaagccc gcggtggctg cagggacaca gagcctcggg
      721 aacttccggc agggcttcat gaagtgcttg ctggaggtgg agaaaatgga ggcctcccat
      781 cggagagcct cgaaggcccg gtcccagaca gcccagaagt cgcccaggac cctgaccccg
      841 gtgcccacct cagctccaag cctgcctcag acccctgcct cggtccctgc cagcggccca
      901 tcgtgggccc ggctgccagc tcctgggcca gaacctgccc ccatgggagc cccggtcccc
      961 acctccatgc cttgccctgt cctgctgggc cctgccctgg acctgggctg gagaaggatg
     1021 gaactcttgc accagagcag cgagagaacc ctgagctacg ccaaggcgcg gcaggagccg
     1081 gaagagcaga gcctccaaaa gctttatcaa aaccgggaga agtccgagga gcaactgacc
     1141 ctgaagcaag aggaagcctt ccgcagctac tttgagatct tcaatggtcc tggtgaggtg
     1201 gatgcacaga gcctgaagaa tatcctgctc ctaatgggct tctctgtgac gctggcccag
     1261 gtggaggacg ccctgatgag tgctgatgtc aatggagatg gtcgtgtgga cttcaaagac
     1321 ttcttggctg tgatgacaga caccaggcgc ttcttctgct ctgtggaaca gaacgccctg
     1381 tcggacatgg ctccccacaa cccccacact ctactctttg agatcctgtc cctgctggta
     1441 gagatgctgg ccttaccaga ggcagtctta gaggaaatca caaactacta ccagaaaaag
     1501 ctgaaggaag gcacctgcaa ggcccaggag atggaagcgg ccgtaggccg gctgcggttg
     1561 cagaagcttc cctacaaccc ccagcaagaa gagagctcag aagttccaga acgaaaggtc
     1621 ctcagtatcc tgagccggct gaagcagcag aactatgctc ccaacctgca gagcccctat
     1681 gcccaggtgc cctgcatcct gctctgccca cagctggaca agaagatggt ccgtaggcag
     1741 ccgagcaacc actatgcact agaccagtgc acaccccctg gcctggatcc tgacatccgc
     1801 agccccttct tccagtcagg atctcaagga aacagggaac acaactctga cagcagaaag
     1861 tggctcagct ctgtgccagc tcgaacccac tgaccctctg gaggcctgac tctaggcagc
     1921 tgctcaaggc ctgtagacag atgggccacc aggcaggagc tgctgctggg atttgctttt
     1981 gtggcctggt gagctaataa acaccaataa cttca
//
