LOCUS       NM_001397487            2983 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens spermatogenesis associated 1 (SPATA1), transcript
            variant 1, mRNA.
ACCESSION   NM_001397487
VERSION     NM_001397487.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2983)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL359762.24.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000699524.1/
                                                ENSP00000514414.1
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AL359762.24        16631-16663
            34-206              AL359762.24        26468-26640
            207-313             AL359762.24        30830-30936
            314-431             AL359762.24        32635-32752
            432-485             AL359762.24        35941-35994
            486-714             AL359762.24        36090-36318
            715-829             AL359762.24        43105-43219
            830-887             AL359762.24        43954-44011
            888-990             AL359762.24        54447-54549
            991-1116            AL359762.24        55879-56004
            1117-1295           AL359762.24        59031-59209
            1296-1394           AL359762.24        60677-60775
            1395-1464           AL359762.24        66155-66224
            1465-2983           AL359762.24        76106-77624
FEATURES             Location/Qualifiers
     source          1..2983
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p22.3"
     gene            1..2983
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="spermatogenesis associated 1"
                     /db_xref="GeneID:100505741"
                     /db_xref="HGNC:HGNC:14682"
     exon            1..33
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            34..206
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1493
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sperm-specific protein SP-2; spermatogenesis-associated
                     protein 1"
                     /codon_start=1
                     /product="spermatogenesis-associated protein 1 isoform 1"
                     /protein_id="NP_001384416.1"
                     /db_xref="CCDS:CCDS90993.1"
                     /db_xref="GeneID:100505741"
                     /db_xref="HGNC:HGNC:14682"
                     /translation="MSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVVNKFISA
                     GFLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKLKSFA
                     PPYALQPELYLLPVMDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKEEL
                     GRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTK
                     KSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREK
                     IIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASM
                     EEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQL
                     KRKLDTDKMKLIVEVKLLEVCLARRSTEDFVYDESAKSKGSIGCCNTF"
     exon            207..313
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            314..431
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..485
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            486..714
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            715..829
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..887
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            888..990
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1116
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1295
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1394
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1395..1464
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..2983
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2653..2658
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="hexamer: ATTAAA"
     polyA_site      2677
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
     regulatory      2688..2693
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="hexamer: AATAAA"
     polyA_site      2715
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="major polyA site"
     regulatory      2949..2954
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
                     /note="hexamer: AATAAA"
     polyA_site      2971
                     /gene="SPATA1"
                     /gene_synonym="SP-2; SPAP1"
ORIGIN      
        1 cttttcctct ccagaggggc cgattaggga gagagaccag aaatgagtgg aatgctatct
       61 taagccaaaa aaaactatta taatttttat ttagtactac ttaaatgaag aaagataaaa
      121 aaagaaacaa aattccaatt gataattatc ccattcagac attagtgaat atgtcactca
      181 atccaagtcg accttcctca tcagagttgg tggaacttca tgttttttat gtccctgaag
      241 gatcatggaa ctataagcta aataccattt caacagaagt tgttaacaaa ttcatttcag
      301 ctggatttct aagagtatct cctcaactta ctttacgagc cctgagggag cgtcttggtg
      361 agttcctggg tgaagatgct attgcagaaa aatttttatt tctgaaatgc attggaaata
      421 atttagctgt ggtgaaggaa aagcaagaat cagaactgaa actcaaatca tttgctcctc
      481 catatgctct tcaaccagaa ttatatttgc ttcctgtaat ggaccattta ggaaatgttt
      541 attcaccatc aacagttatt ttagatgagc ggcagactaa taatggtgtt aatgaggctg
      601 atggaacaat ccacagacca attagtgtaa ctttgttcaa ggaggaactt ggaagagatc
      661 ccagtttgtt agaaaacact ttgaaagagc ttcctaacaa gaatcaggaa gaagctgggg
      721 gaaaagccac tgcagaaaaa agccaaattg caaaaaatca aattggaaat tctgagttgc
      781 caggatcatt ggaagattca aataatgatt gctttggcac taaaaaaagt cagtgtcttt
      841 gggaaaatga agatgataca gctatcagta gaagacagga caatcagaca gctgaaaaag
      901 agtacatcac cctaccagat cacccttcac ttccttgtca acctgttctt tcttcaggaa
      961 taactgatat atctttatta caaactgaaa gagagaagat tatcaaacaa atgaaacaag
     1021 taaaggaaga aagaaggtat ctggaaagaa atagagaaga actagtaaaa acggttgaaa
     1081 agctatttga acaaagcaaa ttaaaacgat atcatgccta caatggttgg aagaaaaaat
     1141 acttggaaac aaagaaagtc acagcatcaa tggaggaggt tttaacaaaa cttcgagaag
     1201 atttggaact ctactataaa aaactgctca tgcaacttga agccagggag atcaagatga
     1261 gaccaaagaa tctggcaaac atcacagact ccaagaatta cctaataatc cagatcactg
     1321 aggtacagca tgcaattgac cagcttaaga gaaaactaga tactgacaaa atgaaactca
     1381 tagtagaagt taagttgcta gaagtgtgcc tggctaggag gtctacagaa gattttgttt
     1441 atgatgaatc agccaagtca aaagggagca ttggctgctg caatacattc tgaccagatc
     1501 tgactttgtt catcataaga catcacaaag aggaagtcac aagcatctgc gattccagta
     1561 taattatagc atcttctgtc tatgttcttt ggagaccaag ctacatcaaa ggttacctgt
     1621 ggaaaaaaat cttactattt tatgtaatat gatcacgtgt gcatattacg tcagattttt
     1681 aaaattatat atatttttta ccttatacta cacaaggaaa aggaactgct tacagtatat
     1741 gaatgtaggg tttgacacac atagaacttg aaccattcta agaaatattt tttgcttaca
     1801 cttgactgag tcagacatat atttggacat acaatgacca ggagcaagac actatataga
     1861 agatggcctt caaactcaaa atgtcttcaa acgctaggct ggtacctcag ctgattaaaa
     1921 gaagcaggta taatgacaac agggtatggt gatgcccctg agcaactaga gagtaaaggc
     1981 acactaaaag aattcaaata caaaagtttt taaaatattg tgcaggttaa atatgtcacc
     2041 tgttggcaca acctgactgg gttgggagtt tcagcctgat tcacaatcac cttatatggt
     2101 agatttggcc caatattaca gttaagacaa tagtggtgtc ttacggccta caggtataga
     2161 ttaatcaagt caaaatgttg aataaatcat ttaaatgatc ttattttacg gaaatattca
     2221 aataaatgtt gagtattatc tttctttttt gggggggatg gagtcttgct ctgtcaccca
     2281 gggtggagtg cagtggcgca atctcagctc actgcaacct ctgcctcctg ggttcaagtg
     2341 attctcctgc ctcagcctcc cacatagctg ggattacagg catgcgccac cacgcccagc
     2401 taattttttt gtatttttag tagagacagg gttttgccat gttgcccagg ctggtctcaa
     2461 actcctgacc tcagctgatc tgccgatctc agcctcccaa agtgcttaca ggcgtgagcc
     2521 accacaccca gccttatctt tcattttgaa tagtgagcca gccttcaaca agaatgtgtc
     2581 tctttatgtt tattgcctta accaaatatt aattagcctt attttataca tgtacaaatg
     2641 ttctaaaact tcattaaagg ttgttttccc cccttaatta ggcactcaat aaacactgat
     2701 tattttaaaa actgagatac tttaggtaac atttttatac tttgaacaat ttattctagc
     2761 aaaactcttt ttaggacttc ttcaaagttc cctttataat tccgtgaata ttagcacttt
     2821 ataattataa gctttgctca gtagttttcc aacaaaataa gttatgaaat aaaattatta
     2881 catatttgtt cctattttat cactgcctct tattacaaaa tgagaggtat attatagtaa
     2941 tagagaaaaa taaatgacta cctctaagca agtaaatttc caa
//
