LOCUS       NM_001009616             642 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens SPANX family member N5 (SPANXN5), mRNA.
ACCESSION   NM_001009616
VERSION     NM_001009616.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Westbrook,V.A., Schoppee,P.D., Vanage,G.R., Klotz,K.L.,
            Diekman,A.B., Flickinger,C.J., Coppola,M.A. and Herr,J.C.
  TITLE     Hominoid-specific SPANXA/D genes demonstrate differential
            expression in individuals and protein localization to a distinct
            nuclear envelope domain during spermatid morphogenesis
  JOURNAL   Mol Hum Reprod 12 (11), 703-716 (2006)
   PUBMED   17012309
REFERENCE   2  (bases 1 to 642)
  AUTHORS   Kouprina,N., Mullokandov,M., Rogozin,I.B., Collins,N.K.,
            Solomon,G., Otstot,J., Risinger,J.I., Koonin,E.V., Barrett,J.C. and
            Larionov,V.
  TITLE     The SPANX gene family of cancer/testis-specific antigens: rapid
            evolution and amplification in African great apes and hominids
  JOURNAL   Proc Natl Acad Sci U S A 101 (9), 3077-3082 (2004)
   PUBMED   14973187
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC244505.1 and AL039107.1.
            
            On May 17, 2019 this sequence version replaced NM_001009616.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2144835 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375511.4/ ENSP00000364661.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               AC244505.1         66966-67119
            155-485             AC244505.1         67762-68092
            486-640             AL039107.1         3-157
            641-642             AC244505.1         68248-68249
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.22"
     gene            1..642
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /note="SPANX family member N5"
                     /db_xref="GeneID:494197"
                     /db_xref="HGNC:HGNC:33178"
                     /db_xref="MIM:300668"
     exon            1..154
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..298
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /note="cancer/testis antigen family 11, member 10;
                     nuclear-associated protein SPAN-Xn5"
                     /codon_start=1
                     /product="sperm protein associated with the nucleus on the
                     X chromosome N5"
                     /protein_id="NP_001009616.1"
                     /db_xref="CCDS:CCDS35295.1"
                     /db_xref="GeneID:494197"
                     /db_xref="HGNC:HGNC:33178"
                     /db_xref="MIM:300668"
                     /translation="MEKPTSSTNGEKRKSPCDSNSKNDEMQETPNRDLVLEPSLKKMK
                     TSEYSTVLVLCYRKTKKIHSNQLENDQS"
     exon            155..642
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      618..623
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /note="hexamer: AATAAA"
     polyA_site      642
                     /gene="SPANXN5"
                     /gene_synonym="CT11.10; SPANX-N5"
                     /note="major polyA site"
ORIGIN      
        1 actgggaagc ttcaatatag ctgtggaagt ctggactcta caagatcctg ctgtagacat
       61 tcaacaacca accagaatca tggaaaagcc cacttcaagc accaatgggg agaagaggaa
      121 gagcccctgt gactccaaca gcaaaaatga tgagatgcag gagacaccaa acagggactt
      181 agtcctcgaa ccgagtttga aaaagatgaa aacatcagaa tattcaacag tattagtgtt
      241 gtgctacagg aagactaaga aaatacattc aaatcaactc gagaatgacc agtcctgaga
      301 gaactccatc aatccagtcc aagaggagga ggacgaagga tcctcacagg aggacgaaga
      361 cctagactca tctgcagaat cttcaaagca ggatgaagac ctacaattac ctgaaggatc
      421 ttcacaggag gatgaagacc tagggttatc tgaaggatct tcacaagagg atgaagacct
      481 agactcatct gaaggatctt tgatggagga agaagaccca gactcatctg aaggatcgtc
      541 agaggagggt gaggaagact aattaaacat ggagaaacca aattggacaa atcctcacca
      601 ccaacggtga tgattacaat aaaatcaagt ttgagaagct ga
//
