LOCUS       NM_001009609             590 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens SPANX family member N3 (SPANXN3), mRNA.
ACCESSION   NM_001009609 XM_066457
VERSION     NM_001009609.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 590)
  AUTHORS   Westbrook,V.A., Schoppee,P.D., Vanage,G.R., Klotz,K.L.,
            Diekman,A.B., Flickinger,C.J., Coppola,M.A. and Herr,J.C.
  TITLE     Hominoid-specific SPANXA/D genes demonstrate differential
            expression in individuals and protein localization to a distinct
            nuclear envelope domain during spermatid morphogenesis
  JOURNAL   Mol Hum Reprod 12 (11), 703-716 (2006)
   PUBMED   17012309
REFERENCE   3  (bases 1 to 590)
  AUTHORS   Kouprina,N., Mullokandov,M., Rogozin,I.B., Collins,N.K.,
            Solomon,G., Otstot,J., Risinger,J.I., Koonin,E.V., Barrett,J.C. and
            Larionov,V.
  TITLE     The SPANX gene family of cancer/testis-specific antigens: rapid
            evolution and amplification in African great apes and hominids
  JOURNAL   Proc Natl Acad Sci U S A 101 (9), 3077-3082 (2004)
   PUBMED   14973187
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC062750.1 and DQ336129.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001009609.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062750.1, DQ336128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000370503.2/ ENSP00000359534.2
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                BC062750.1         5-88
            85-510              DQ336129.1         1-426
            511-590             BC062750.1         515-594
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq27.3"
     gene            1..590
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /note="SPANX family member N3"
                     /db_xref="GeneID:139067"
                     /db_xref="HGNC:HGNC:33176"
                     /db_xref="MIM:300666"
     exon            1..162
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..510
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /note="cancer/testis antigen family 11, member 8;
                     nuclear-associated protein SPAN-Xn3"
                     /codon_start=1
                     /product="sperm protein associated with the nucleus on the
                     X chromosome N3"
                     /protein_id="NP_001009609.2"
                     /db_xref="CCDS:CCDS35418.1"
                     /db_xref="GeneID:139067"
                     /db_xref="HGNC:HGNC:33176"
                     /db_xref="MIM:300666"
                     /translation="MEQPTSSTNGEKTKSPCESNNKKNDEMQEVPNRVLAPEQSLKNT
                     KTSEYPIIFVYYLRKGKKINSNQLENEQSQENSINPIQKEEDEGVDLSEGSSNEDEDL
                     GPCEGPSKEDKDLDSSEGSSQEDEDLGLSEGSSQDSGED"
     exon            163..590
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      566..571
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /note="hexamer: AATAAA"
     polyA_site      590
                     /gene="SPANXN3"
                     /gene_synonym="CT11.8; SPANX-N3"
                     /note="major polyA site"
ORIGIN      
        1 atcccactgg gaagcttcaa catagctgtg gaagtctgca gtctacagga gcctactata
       61 gacattctac aaccaaccag aatcatggaa cagccaactt ccagcaccaa tggggagaag
      121 acgaagagcc cctgtgaatc caataacaaa aaaaatgatg agatgcaaga ggtaccaaac
      181 agagtcttag cccccgaaca gagtttgaag aacacaaaaa catcagaata tccaataata
      241 tttgtgtatt acctcaggaa gggtaagaaa ataaattcaa atcaactgga gaatgaacag
      301 tcccaagaga actccatcaa tccaatccaa aaggaggagg acgaaggcgt agacttatct
      361 gaaggatctt caaatgagga tgaagaccta ggcccatgtg aaggaccttc aaaggaggac
      421 aaagatctag actcatctga aggatcctca caggaggatg aagacctagg cttatctgaa
      481 ggatcttcac aggacagtgg ggaggattag tcacacatgg agaaaccaaa ttggacaaat
      541 catcaccact gatggcgatg attacaataa aatcaagttt aaggagctga
//
