LOCUS       NM_001395484             551 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens sperm associated antigen 11A (SPAG11A), transcript
            variant 3, mRNA.
ACCESSION   NM_001395484
VERSION     NM_001395484.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Nusbaum,C., Mikkelsen,T.S., Zody,M.C., Asakawa,S., Taudien,S.,
            Garber,M., Kodira,C.D., Schueler,M.G., Shimizu,A., Whittaker,C.A.,
            Chang,J.L., Cuomo,C.A., Dewar,K., FitzGerald,M.G., Yang,X.,
            Allen,N.R., Anderson,S., Asakawa,T., Blechschmidt,K., Bloom,T.,
            Borowsky,M.L., Butler,J., Cook,A., Corum,B., DeArellano,K.,
            DeCaprio,D., Dooley,K.T., Dorris,L. 3rd, Engels,R., Glockner,G.,
            Hafez,N., Hagopian,D.S., Hall,J.L., Ishikawa,S.K., Jaffe,D.B.,
            Kamat,A., Kudoh,J., Lehmann,R., Lokitsang,T., Macdonald,P.,
            Major,J.E., Matthews,C.D., Mauceli,E., Menzel,U., Mihalev,A.H.,
            Minoshima,S., Murayama,Y., Naylor,J.W., Nicol,R., Nguyen,C.,
            O'Leary,S.B., O'Neill,K., Parker,S.C., Polley,A., Raymond,C.K.,
            Reichwald,K., Rodriguez,J., Sasaki,T., Schilhabel,M., Siddiqui,R.,
            Smith,C.L., Sneddon,T.P., Talamas,J.A., Tenzin,P., Topham,K.,
            Venkataraman,V., Wen,G., Yamazaki,S., Young,S.K., Zeng,Q.,
            Zimmer,A.R., Rosenthal,A., Birren,B.W., Platzer,M., Shimizu,N. and
            Lander,E.S.
  TITLE     DNA sequence and analysis of human chromosome 8
  JOURNAL   Nature 439 (7074), 331-335 (2006)
   PUBMED   16421571
REFERENCE   2  (bases 1 to 551)
  AUTHORS   Frohlich,O., Po,C. and Young,L.G.
  TITLE     Organization of the human gene encoding the epididymis-specific EP2
            protein variants and its relationship to defensin genes
  JOURNAL   Biol Reprod 64 (4), 1072-1079 (2001)
   PUBMED   11259252
REFERENCE   3  (bases 1 to 551)
  AUTHORS   Hamil,K.G., Sivashanmugam,P., Richardson,R.T., Grossman,G.,
            Ruben,S.M., Mohler,J.L., Petrusz,P., O'Rand,M.G., French,F.S. and
            Hall,S.H.
  TITLE     HE2beta and HE2gamma, new members of an epididymis-specific family
            of androgen-regulated proteins in the human
  JOURNAL   Endocrinology 141 (3), 1245-1253 (2000)
   PUBMED   10698202
REFERENCE   4  (bases 1 to 551)
  AUTHORS   Osterhoff,C., Kirchhoff,C., Krull,N. and Ivell,R.
  TITLE     Molecular cloning and characterization of a novel human sperm
            antigen (HE2) specifically expressed in the proximal epididymis
  JOURNAL   Biol Reprod 50 (3), 516-525 (1994)
   PUBMED   8167223
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130365.5.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN03465420
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000642566.2/ ENSP00000496500.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC130365.5         155978-156077       c
            101-253             AC130365.5         155242-155394       c
            254-551             AC130365.5         143142-143439       c
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p23.1"
     gene            1..551
                     /gene="SPAG11A"
                     /gene_synonym="EDDM2A; HE2"
                     /note="sperm associated antigen 11A"
                     /db_xref="GeneID:653423"
                     /db_xref="HGNC:HGNC:33342"
     exon            1..100
                     /gene="SPAG11A"
                     /gene_synonym="EDDM2A; HE2"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..441
                     /gene="SPAG11A"
                     /gene_synonym="EDDM2A; HE2"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 3; epididymal protein 2A; sperm antigen HE2; human
                     epididymis-specific protein 2; antimicrobial-like protein
                     Bin-1b"
                     /codon_start=1
                     /product="sperm-associated antigen 11A isoform 3
                     precursor"
                     /protein_id="NP_001382413.1"
                     /db_xref="CCDS:CCDS94257.1"
                     /db_xref="GeneID:653423"
                     /db_xref="HGNC:HGNC:33342"
                     /translation="MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAP
                     GQGTNGFQLLRHAVKRDLLPPRTPPYQGDVPLGIRNTICRMQQGICRLFFCHSGEKKR
                     DISSDPWNRCCVSNTDEEGKEKPEMDGRSGI"
     exon            101..253
                     /gene="SPAG11A"
                     /gene_synonym="EDDM2A; HE2"
                     /inference="alignment:Splign:2.1.0"
     exon            254..551
                     /gene="SPAG11A"
                     /gene_synonym="EDDM2A; HE2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accctgggtg ctttctggct tgcagtgctc ttggcagaca tgaggcaacg attgctcccg
       61 tccgtcacca gccttctcct tgtggccctg ctgtttccag gatcgtctca agccagacat
      121 gtgaaccact cagccactga ggctctcgga gaactcaggg aaagagcccc tgggcaaggc
      181 acaaacgggt ttcagctgct acgccacgca gtgaaacggg acctcttacc accgcgcacc
      241 ccaccttacc aaggggatgt tccactggga attagaaata ccatctgccg tatgcagcaa
      301 gggatctgca gacttttttt ctgccattct ggtgagaaaa agcgtgacat tagctctgat
      361 ccctggaata ggtgttgcgt atcaaataca gatgaagaag gaaaagagaa accagagatg
      421 gatggcagat ctgggatcta aaatataagc tcccggaagg cagggatgtt gaagtatccc
      481 aagggcttaa aggaatgtgt ggcttatagt aggtgttcaa taaatatttg ttgaatgaat
      541 ttagcaccaa a
//
