LOCUS       NM_175873               3485 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens sosondowah ankyrin repeat domain family member A
            (SOWAHA), mRNA.
ACCESSION   NM_175873
VERSION     NM_175873.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3485)
  AUTHORS   Maeso,I., Irimia,M., Tena,J.J., Gonzalez-Perez,E., Tran,D.,
            Ravi,V., Venkatesh,B., Campuzano,S., Gomez-Skarmeta,J.L. and
            Garcia-Fernandez,J.
  TITLE     An ancient genomic regulatory block conserved across bilaterians
            and its dismantling in tetrapods by retrogene replacement
  JOURNAL   Genome Res 22 (4), 642-655 (2012)
   PUBMED   22234889
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004775.1 and KC877113.1.
            
            On May 17, 2019 this sequence version replaced NM_175873.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378693.4/ ENSP00000367965.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1671              AC004775.1         11607-13277         c
            1672-2246           KC877113.1         1-575
            2247-3485           AC004775.1         9793-11031          c
FEATURES             Location/Qualifiers
     source          1..3485
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q31.1"
     gene            1..3485
                     /gene="SOWAHA"
                     /gene_synonym="ANKRD43"
                     /note="sosondowah ankyrin repeat domain family member A"
                     /db_xref="GeneID:134548"
                     /db_xref="HGNC:HGNC:27033"
     exon            1..3485
                     /gene="SOWAHA"
                     /gene_synonym="ANKRD43"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..1970
                     /gene="SOWAHA"
                     /gene_synonym="ANKRD43"
                     /note="ankyrin repeat domain-containing protein 43;
                     protein sosondowah homolog A; ankyrin repeat
                     domain-containing protein SOWAHA"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein SOWAHA
                     precursor"
                     /protein_id="NP_787069.4"
                     /db_xref="CCDS:CCDS43361.1"
                     /db_xref="GeneID:134548"
                     /db_xref="HGNC:HGNC:27033"
                     /translation="MALAAAAAAAAAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLD
                     AGDPRGRAARRDRFKQFVNNVAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQP
                     SKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERS
                     ADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCM
                     LPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSP
                     HLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRD
                     RGLAAKRDFMSGFTALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLA
                     ALHGHEDAAVLLVVRLGAQVHVRDHSGRRAYQYLRPGSSYALRRLLGDPGLRGTTEPD
                     ATGGGSGSLAARRPVQVAATILSSTTSAFLGVLADDLMLQDLARGLKKSSSFSKFLSA
                     SPMAPRKKTKIRGGLPAFSEISRRPTPGPLAGLVPSLPPTT"
     regulatory      3465..3470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SOWAHA"
                     /gene_synonym="ANKRD43"
                     /note="hexamer: AATAAA"
     polyA_site      3485
                     /gene="SOWAHA"
                     /gene_synonym="ANKRD43"
                     /note="major polyA site"
ORIGIN      
        1 acctgtaagg cgagcgcggc gcgggggatg gaagcaggcg cccattggac agaatacaaa
       61 ggcagaaacc taccccgaag gccggggccc ggcggggcgc tgggggtggg cgctccccgc
      121 ggcccccggc gcccttcgcc ccgagacgcc ccggcccagc ggcactggcg cgaccgaggt
      181 ccagcttcgg ggacacgccc ggctggccgc ggggaaggca ccaggtgagc gcggccgcgc
      241 ctcccggaac cccgctcccg cgcgtcccgc ggcgacgcgg cgcccacccg ccccgggagc
      301 caggaaccca gggccccacc atggcgctgg ccgccgccgc cgccgctgcg gctgccgggg
      361 tgagccaggc ggcggtgctg ggcttcctgc aggagcacgg cgggaaggtg cgcaactccg
      421 agctgctgag ccgcttcaag ccgctgctcg atgccggcga cccgcggggc cgcgccgccc
      481 gcagggaccg cttcaagcag ttcgtcaaca acgtggcggt ggtgaaggag ctcgacggcg
      541 tcaagttcgt ggtgctgagg aagaagcccc ggcccccgga gcccgagccc gcacccttcg
      601 gccccccggg ggcagcggcc cagccgtcga aacccacttc gacggtcttg ccgcggagcg
      661 cctctgcccc gggagctccg cccttggtcc gggtgccgcg gccagtggag ccgccagggg
      721 acctgggtct gccaacagag ccacaggaca ccccgggggg gccggcctcc gagcccgctc
      781 agccgcccgg ggagcggtcc gccgacccac cgcttccagc ccttgagcta gcccaggcca
      841 ccgagagacc ctccgcagac gcggccccac cgcctagggc cccttctgag gcggcatcgc
      901 cctgctctga tccgccagac gcggagcccg ggcccggggc agcgaaaggg ccgccgcagc
      961 agaagccctg tatgctgccg gtgcgctgcg tcccggcccc cgccacgctc cgcctccggg
     1021 cggaggagcc cggcctgcgc cggcagctgt cggaggagcc gagcccgcgg agctcccctc
     1081 tgctgctgag gcggctctcg gtggaagagt ccggtctggg cctcggcctg ggcccgggcc
     1141 gctccccgca cctgaggcgc ctgtcgcgcg ccggcccgcg tctgctgagc cctgacgccg
     1201 aggagttgcc cgccgcgccg ccgccgtccg cggtgcccct ggagccgtcc gagcacgagt
     1261 ggctcgtgcg gactgccggg ggccgctgga cccaccagct gcacgggctg ctgctgcgcg
     1321 accgcggctt ggcggccaag cgcgacttca tgtctggctt cacggccctg cattgggccg
     1381 ccaagagcgg cgacggcgag atggcgctgc agctggtgga ggtcgcgcgg cgcagtggcg
     1441 caccagtcga cgtgaacgca cgctcccacg gcggctacac gccgctgcac ctggctgcac
     1501 tgcacggcca cgaggacgct gccgtgctgc tggtggtgcg tctgggtgcc caggtgcacg
     1561 tgcgtgatca cagcgggcgt cgcgcctacc agtacctgcg gcccggctcc tcgtacgcgc
     1621 tgcgccgcct tcttggcgat ccaggcctgc gaggcaccac ggagccagat gcgaccggtg
     1681 gtggaagtgg cagtcttgct gccaggcgcc ccgtacaggt ggccgccacc atcctcagtt
     1741 ccaccaccag tgcatttctg ggcgtcctgg ctgacgacct catgctccag gacctggccc
     1801 gaggcttgaa gaagtcgagc tccttcagca agttcttgag cgcctcgccc atggctccac
     1861 gtaaaaagac aaagatccgc ggtggtctgc cagccttctc agaaatctct cgtcgaccta
     1921 ctccggggcc tttagctggt ctagtgccca gtttgcctcc aacaacctga aggtccctgg
     1981 ggctaccacc tggttgatct atcgtggcct gctcgtcgca gtccaaaccc gcccaagact
     2041 gcagcccaat caacgcctgg agcctcattc tgtttccagc tttgtccagg gcagcctgtt
     2101 ttacccagat gggcctgcac ctccagcttc tttctgaagc atgacccatc tccagagatg
     2161 ggatttgaga aatcagtgag agcttcctat aaagaactcc aggagacagg cctgaactct
     2221 agagggaact tgaaatccag ggtcaaaggt taaggggcag cagctggtct ggcccctgaa
     2281 agccttcacc tgatgcctct gcagctacac aatcccaaga cagagctaga gcaagggtct
     2341 ctttaaatgt tgaaagatgt taggttgtca gctttaagat atgtggtggt tttgtaattt
     2401 gatgctttta ttctgttttt aaattgaaat gaggtaatgc aactttcgta ataacctttt
     2461 ggaattatat ttttccactt ttaggcaaag tgcttagaca ttttcaattt tttttttgct
     2521 aaatactttg gaattctatt taaaaaatag atgatcaaga tctaaaggaa attaatccca
     2581 accaacaaac ttaaaagttt atctacctcg ttttaggcaa tcaagattct ggagagtctt
     2641 gaacacagaa taacgattgt gaccattatg aatgtaacta atttcagttg tactgtgaat
     2701 gctaaatatt tgcaaacaag tacatcttga aagtaaaggt gacttagaga aaagagacat
     2761 tttgacagat acttttaatt tgtggttgtc tccatcatga aatagaaacg tgtttggcac
     2821 ttgtgggtgg ctattttgat ttggcatgac tacttaattt tttaaaaaaa ttgtggtttg
     2881 tgaattgcac ctttgtgcca tgtttctgaa tctggttttc aaatccagtg gagcctttca
     2941 gtgaaatagg tgactattaa aaaagtaata gtattacaga aaaatgagcg attaaatagt
     3001 aatggataca attaaggagc aactatttta tatgactgtt ctgtacaaac aaaaagtatg
     3061 taatacccat tttaaaaaac catttgaaag tagacaactt attccaaaat agcaaatgca
     3121 gaatctctgc tcagtgagct tggatgagtg gcttaacttc tctgggcctt tgttcctatc
     3181 tgtaaatgag aaagtttgta gatattgcca agatttccca ggctcaatac agtgtaatta
     3241 ttttatgttt taaagatatg aaatctgttt actcaaccaa ttttttaaat gtcatattgt
     3301 gataatgctc tgcttttgca aattgtgttt gcatgtcatt agttatatca aatagttttg
     3361 tggcatgggg tagtggagct tccctcccca cccccatatg tatcagtgaa gcctttgaaa
     3421 ttacttaagg cagtctttca tggaatgttt tgattgagca atgaaataaa cagtcctcca
     3481 ttttg
//
