LOCUS       XM_005245510            6370 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens sorting nexin 27 (SNX27), transcript
            variant X2, mRNA.
ACCESSION   XM_005245510
VERSION     XM_005245510.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005245510.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6370
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6370
                     /gene="SNX27"
                     /gene_synonym="MRT1; MY014"
                     /note="sorting nexin 27; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 24 ESTs, 3912 long SRA reads, 5 Proteins, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 41 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:81609"
                     /db_xref="HGNC:HGNC:20073"
                     /db_xref="MIM:611541"
     CDS             391..1707
                     /gene="SNX27"
                     /gene_synonym="MRT1; MY014"
                     /codon_start=1
                     /product="sorting nexin-27 isoform X2"
                     /protein_id="XP_005245567.1"
                     /db_xref="GeneID:81609"
                     /db_xref="HGNC:HGNC:20073"
                     /db_xref="MIM:611541"
                     /translation="MNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSD
                     DSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQ
                     NLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLS
                     ESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALF
                     EVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTY
                     FFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSR
                     RKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEK
                     KPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT"
ORIGIN      
        1 accccgcgcc agcagctcgg tggccgagtc ggtcccgcgg ccggcggatc gggcgcgcgc
       61 gtcgggggtc gtccggctgc caggcagggc gagcacgcgc cgggaggcct tggaggcgta
      121 gggggcgggg gtacggctcg cctgctcgca agatggcgga cgaggacggg gaagggattc
      181 atccctcagc ccctcacagg aacggaggtg gcggcggcgg cggggggtct gggctccact
      241 gcgccgggaa cggcggcggg ggaggcggcg gcccgcgggt cgtgcgcatc gtcaagtccg
      301 agtccggcta cggcttcaac gtgcggggcc aagtgagcga gggcgggcaa ctgcggagca
      361 tcaacgggga gctgtacgcg ccgctgcagc atgaaccacg tgaatgttga gggggcgaca
      421 cacaagcagg tggtggacct gattcgagca ggcgagaagg aattgatctt gacagtgtta
      481 tctgtacctc ctcatgaggc agataaccta gatcccagtg acgactcgtt gggacaatca
      541 ttttatgatt acacagaaaa gcaagcagtg cccatatcgg tccccagata caaacatgtg
      601 gagcagaatg gtgagaagtt tgtggtatat aatgtttaca tggcagggag gcagctgtgt
      661 tctaagcggt accgggagtt tgctatccta caccagaacc tgaagagaga gtttgccaac
      721 tttacatttc ctcgactccc agggaagtgg ccattttcat tatcagaaca acaattagat
      781 gcccgacgtc ggggattgga agaatatcta gaaaaagtgt gttcaatacg agtaattggt
      841 gagagtgaca tcatgcagga attcctatca gaatccgatg agaactacaa tggtgtgtcc
      901 gacgtagagc tgagagtagc attaccagat ggaacaacgg ttacagtcag ggttaaaaag
      961 aacagtacta cagaccaagt atatcaggct atcgcagcaa aggttggcat ggacagtacg
     1021 acagtgaatt actttgcctt atttgaagtg atcagtcact cctttgtacg taaattggca
     1081 cctaatgagt ttcctcacaa actctacatt cagaattata catcagctgt gccaggcacc
     1141 tgcttgacca ttcgaaagtg gctttttaca acagaagaag aaattctctt aaatgacaat
     1201 gaccttgctg ttacctactt ctttcatcag gcagtcgatg atgtgaagaa aggttacatc
     1261 aaagcagaag aaaagtccta tcaattacag aagctatacg aacaaagaaa aatggtcatg
     1321 tacctcaaca tgctaaggac ttgtgagggc tacaatgaaa tcatctttcc ccactgtgcc
     1381 tgtgactcca ggaggaaggg gcacgttatc acagccatca gcatcacgca ctttaaactg
     1441 catgcctgca ctgaagaagg acagctggag aaccaggtaa ttgcatttga atgggatgag
     1501 atgcagcgat gggacacaga tgaagaaggg atggccttct gtttcgaata tgcacgagga
     1561 gagaagaagc cccgatgggt taaaatcttc acgccatatt tcaattacat gcatgagtgc
     1621 ttcgagaggg tgttctgcga gctcaagtgg agaaaagaga acattttcca gatggcgagg
     1681 tcacagcaga gagatgtggc cacctagcct ttccttatcc ccttcccttc ccttcacccc
     1741 catcctctta ctcctttcat gtcccatttc agacagagta accattaaca aaaaagaaga
     1801 gaaaaagtta aagtcgttat attcaaaagc cctaaactaa atattattaa taaccccctc
     1861 tgaatttcat gtctctggaa ttgaggtggt agtgaacagc agatcggtca gcaccagaag
     1921 tcaactgagt taaggcagga aaagaaataa gcccaaccaa cttgccaaag gtatctttgt
     1981 cctttcacct gggcctcata ccaacagcct ctccttgtac tatattttta aaactggaac
     2041 tatgaacttc atccatttgc actgttcaga catatatatg tatgtatgta aaaattatat
     2101 atacacaaat tagctgcacg tatatacata tatatatttc tttttaaatt tcatattgat
     2161 ggcagtacct tttttagctt gtgtttttac acacctttca ctagaatcca tgacctccct
     2221 cgtgctctct ttcttttgaa acaaacttta aaaaggaaaa aaaagcattt tacagggaaa
     2281 aatacctctc ctcatgaagg acttgaaaag tttacaacct gcttggattt ttgccccttt
     2341 ttttgtattg agtatagatt ccggctcatg ggttgccata gagtctagga acaaggagta
     2401 tagtttcttt atcttccaag agggtgctgg ggaggagaaa gaggtgtgtt tctcaaggtt
     2461 aacaggctgt agttctgcag ggagagcctg aagtcctggt atgggctctt gattctgtga
     2521 caattttttt gatccatcta tttctctcac tcctggcttt ctagccacat tctgcacctc
     2581 cttcctgctt tcctagagcc tcggtatgct ttccctcaac cgaccctggc tcaggaggtt
     2641 gatgccatgg gaacctgaac ctgaaacact tcatggtagt aatttcctgt tttccttgcc
     2701 tttttttttt tttttttttt ttttttctga gacagggtct tactctgtcg cccagactgg
     2761 aatgtggtgg catgaacata gctcactgtt accttgaatt ctgggctcag gtgatccttc
     2821 cgcctcaccc tcctgagtag ctgggactac aggtgtgcac caccacacct ggctaattct
     2881 tcttaaaatt tttttgtaga gacagggtct cactatgttg cccaggctgg tctcaaactc
     2941 ctggcctcag gtgatcctct tgtctcagcc tcccaaagtg ctgggattac aggcatgagc
     3001 cactgtgtcc ttccctgcct tttttgcagc agggatagta ctcaggacca gagttaagct
     3061 gataccttag gcacacaggt tggacttaca tagaggaaag aaagcaagaa atgccctatg
     3121 tacatgaggt tttacctcct ccattcctga ccaataacca cccataacta cggcattctc
     3181 tgtgacttcc ttaaacagca gtgatgggaa gggatccaat agtatcttca aggccttggg
     3241 gaaacttgca gtgggtcagt ggtctgtgcc aaccaaacga tagccccatc caagccagct
     3301 gagaacctag gaaggagtag taggaatatg gttgattaga ttggatctcc caagttttaa
     3361 ttgaaaggag actgaacgaa aacctttctg ctttctgtcc gttaaagagc tcctcatctg
     3421 atcttgcagc tagacccttt gagacttaag agctgcatcc caggatcaga agccagggct
     3481 aattggggta ggacaatatt cccagcccct aagctctgta gataatgcat aagaagcacc
     3541 aagtcaggct cagatgcaac taaaacacat ctttgagcct tttctttttc ccttctcccc
     3601 tttctaaaca aaaaccttcc taggatggca tcttttgctc taactgggag acagtcataa
     3661 ttggttgtag tcaattctac taagcagtgt tggggtggtt ggaaagtctc ttttttgtaa
     3721 tttgtttttg caaatcattg tgaggccact ttttctttct ttctttcttt ctttctttct
     3781 ttctttcttt ctttcgttct ttcgttcttt cgttctttct ttctttcttt ctttctcttt
     3841 ctttcttttg ctttccttct ttcatctctt ttttgtaatt tgttgttgca aatcattgtg
     3901 aggccacttt tctttcccct tccttccttc ctttttttct gttttttttt tttttttttc
     3961 ccagagtctt gctctgtcgc ccaggttgga gtgcagtggc acgatctcgg ctcactgcac
     4021 cctctgcctc ttgggttcaa gcgattctcc tgcctcagcc tcccaagtag ctgggattac
     4081 aggcatacac caccacgccc cactaatttt ttgtattttt ggtagggcgg ggtttcacca
     4141 tgatggccag gttggttttg aactcctgac ctcaagtaat ctgcccacct cggcctccca
     4201 aagtgctagg attacaggag tgagccactg cgcctggccc acttttcttt ctttccttct
     4261 tattttgtta tgctggcagc catttgcccc tgcatggtat gggatcaaag aggacagcct
     4321 ttcctccctc accttctcca aatctaggtg aaatcacaga gtacaaaacg tgagaatgct
     4381 gaatgtgtaa agttgcagag ggatccctaa tttgaagact ttgacacaga actaacttct
     4441 tttgacttaa atgaatttaa aatgagccaa aggaccctga aaagaagaca tgttgatttc
     4501 ccactcctag atgctaaaga gacttggcac cagctttgtt caaactgtaa aaatagcaat
     4561 ttgcccctac tcgctcagag tgggacagta gtgaacagag ctgggattcc atgcgacagc
     4621 ttgaatgctg accttcagac atgagacata gggatttgga ggccccttag aatgggtaga
     4681 tggtgttatg ttccctttct ggcatagcat tcacttggtg ctttggagat taggtgaggg
     4741 ccctataggt agttggcctg ttggcagaat ttatttagga acagcccttt tgaaagtgtc
     4801 ccagtaacaa cgcacccagc tgcagcaagg aggtggggaa ggagggcacc ccaaaggaca
     4861 gcgccttctt ctcttccacc catgcacggc cttgggtgat ggaggcgggt tccctgtggc
     4921 tgcgtggatc ccataggatc aagcccttct ttgcatgaag cagtgttgtg actcttctct
     4981 ctccccttcc tctgcacttc ctttctgtaa tccctactgt tcttcttagt cccagcttct
     5041 gcccagggag gcttctaccc agacttcttt tgcaatttgt ccctgggaag agggggtctc
     5101 ccagtgcccc cagcttcatc ccagcagaac cagcaggatc ctcctggtct ctcactggcc
     5161 ttcctccaca cttggtttct atcctcaggg gtagaagctc agagcttttt atggcccagg
     5221 agaaaatgta gaccctgaga aacctgtccc tgcagaaagg ttcccttggg ccatgctttg
     5281 ggccctctgc tctttatatg tttattctat tctccatttt tccaccccgt ccttacccta
     5341 ggcctaaaca caggtacaga tatgtgcatg ctcagggcag ctcctaggcc tggactgagc
     5401 tctcaggggg gaattagata aatattccaa catcctcatg cctggcccat ttagtttcat
     5461 cctttagtta cccaggccag tagctttggg ttatcccttc ctgtagctcc aaacccagca
     5521 cttggagcag caaaataggg cactgacagg agatgaaact ctctcctatc tcagaatttg
     5581 ccaacttctg ggctgggctc ctaggaggta gttttcttga aggggactgc atcctagttg
     5641 acctgaattt tccagaccag gagggactgc tgtgctctcc cttctcgcca tcatactgtt
     5701 tggctagatt cattcagcag tagaagctgt ttgatctgtt gaccccagca tactgctgtt
     5761 tcttcaccag cttcattgtg tcacagtagc ttcctttggg aggatgatgt gatagaacac
     5821 tcagagagag ggagggagaa gagagatagt gggtatgctt ctctagctcc ccatcttcca
     5881 ggtccacctc ttgacttcct gttcccctaa acctgagcac atcacgccag gcctctttgc
     5941 tgccaggaca gcatcagctc actcctcagc aataatctag ggtatgtggg aaggtcaggg
     6001 ctgtggtaag gaatagaatc aaagagggga gtgatacggg gtgggggcac ttggccgcct
     6061 gctaaacttg gacattaatt ttatatcatg accccctttt aagccagtga gctgggcttc
     6121 agtttttccc aggccatgca catttaattt atttcagaga aactctaatt gtattttcac
     6181 tgcagtatct tgtatttttt atttgtgatt taagaaatgt gaagagaaaa tacacagaca
     6241 caataatggc taacattgtt tctttcattc cttgttctag agctaaccac tctaaaattg
     6301 tttggtaatg tcacttagtg taattaattg taacatattc ttttaaataa attgatttat
     6361 tgatcaaaca
//
