LOCUS       NM_001376702            4149 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens synaptosome associated protein 91 (SNAP91), transcript
            variant 36, mRNA.
ACCESSION   NM_001376702
VERSION     NM_001376702.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4149)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 4149)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 4149)
  AUTHORS   Moshkanbaryans,L., Xue,J., Wark,J.R., Robinson,P.J. and Graham,M.E.
  TITLE     A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin
            Binding and Assembly
  JOURNAL   PLoS One 11 (8), e0162050 (2016)
   PUBMED   27574975
  REMARK    GeneRIF: Study concludes that the novel clathrin interaction sites
            identified here in CALM and AP180 have a major role in how these
            proteins interface with clathrin. This work advances the case that
            AP180 and CALM are required to use a combination of standard
            clathrin N-terminal domain binding motifs and the sequence
            identified here for optimal binding and assembling clathrin.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4149)
  AUTHORS   Koo,S.J., Kochlamazashvili,G., Rost,B., Puchkov,D., Gimber,N.,
            Lehmann,M., Tadeus,G., Schmoranzer,J., Rosenmund,C., Haucke,V. and
            Maritzen,T.
  TITLE     Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control
            Efficient Neurotransmission
  JOURNAL   Neuron 88 (2), 330-344 (2015)
   PUBMED   26412491
  REMARK    GeneRIF: To sustain efficient neurotransmission and synaptic
            vesicle formation, AP180 and VAMP2 are required.
REFERENCE   5  (bases 1 to 4149)
  AUTHORS   Busch,D.J., Houser,J.R., Hayden,C.C., Sherman,M.B., Lafer,E.M. and
            Stachowiak,J.C.
  TITLE     Intrinsically disordered proteins drive membrane curvature
  JOURNAL   Nat Commun 6, 7875 (2015)
   PUBMED   26204806
  REMARK    GeneRIF: intrinsically disordered domains are highly potent drivers
            of membrane curvature
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4149)
  AUTHORS   Slepnev,V.I., Ochoa,G.C., Butler,M.H. and De Camilli,P.
  TITLE     Tandem arrangement of the clathrin and AP-2 binding domains in
            amphiphysin 1 and disruption of clathrin coat function by
            amphiphysin fragments comprising these sites
  JOURNAL   J Biol Chem 275 (23), 17583-17589 (2000)
   PUBMED   10748223
REFERENCE   7  (bases 1 to 4149)
  AUTHORS   Traub,L.M., Downs,M.A., Westrich,J.L. and Fremont,D.H.
  TITLE     Crystal structure of the alpha appendage of AP-2 reveals a
            recruitment platform for clathrin-coat assembly
  JOURNAL   Proc Natl Acad Sci U S A 96 (16), 8907-8912 (1999)
   PUBMED   10430869
REFERENCE   8  (bases 1 to 4149)
  AUTHORS   Tebar,F., Bohlander,S.K. and Sorkin,A.
  TITLE     Clathrin assembly lymphoid myeloid leukemia (CALM) protein:
            localization in endocytic-coated pits, interactions with clathrin,
            and the impact of overexpression on clathrin-mediated traffic
  JOURNAL   Mol Biol Cell 10 (8), 2687-2702 (1999)
   PUBMED   10436022
REFERENCE   9  (bases 1 to 4149)
  AUTHORS   Yao,P.J., Morsch,R., Callahan,L.M. and Coleman,P.D.
  TITLE     Changes in synaptic expression of clathrin assembly protein AP180
            in Alzheimer's disease analysed by immunohistochemistry
  JOURNAL   Neuroscience 94 (2), 389-394 (1999)
   PUBMED   10579202
REFERENCE   10 (bases 1 to 4149)
  AUTHORS   Murphy,J.E., Hanover,J.A., Froehlich,M., DuBois,G. and Keen,J.H.
  TITLE     Clathrin assembly protein AP-3 is phosphorylated and glycosylated
            on the 50-kDa structural domain
  JOURNAL   J Biol Chem 269 (33), 21346-21352 (1994)
   PUBMED   8063760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL109915.10.
            
            Transcript Variant: This variant (36), as well as variants 37-41,
            encodes isoform o.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                AL109915.10        166716-166783       c
            69-228              AL109915.10        165188-165347       c
            229-371             AL109915.10        122829-122971       c
            372-447             AL109915.10        119737-119812       c
            448-550             AL109915.10        118892-118994       c
            551-644             AL109915.10        116389-116482       c
            645-756             AL109915.10        114144-114255       c
            757-863             AL109915.10        98486-98592         c
            864-905             AL109915.10        80691-80732         c
            906-976             AL109915.10        74359-74429         c
            977-1004            AL109915.10        68040-68067         c
            1005-1114           AL109915.10        65089-65198         c
            1115-1233           AL109915.10        63075-63193         c
            1234-1248           AL109915.10        58975-58989         c
            1249-1416           AL109915.10        58661-58828         c
            1417-1524           AL109915.10        51764-51871         c
            1525-1788           AL109915.10        50868-51131         c
            1789-1860           AL109915.10        50336-50407         c
            1861-1944           AL109915.10        49845-49928         c
            1945-2028           AL109915.10        48601-48684         c
            2029-2163           AL109915.10        39612-39746         c
            2164-2313           AL109915.10        37840-37989         c
            2314-2344           AL109915.10        33413-33443         c
            2345-2456           AL109915.10        32400-32511         c
            2457-2540           AL109915.10        18254-18337         c
            2541-2645           AL109915.10        17494-17598         c
            2646-2748           AL109915.10        13533-13635         c
            2749-4149           AL109915.10        10275-11675         c
FEATURES             Location/Qualifiers
     source          1..4149
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q14.2"
     gene            1..4149
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /note="synaptosome associated protein 91"
                     /db_xref="GeneID:9892"
                     /db_xref="HGNC:HGNC:14986"
                     /db_xref="MIM:607923"
     exon            1..68
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            69..228
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..2738
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /note="isoform o is encoded by transcript variant 36;
                     clathrin coat assembly protein AP180; assembly protein,
                     180kDa; phosphoprotein F1-20; synaptosome associated
                     protein 91kDa; 91 kDa synaptosomal-associated protein;
                     clathrin coat-associated protein AP180;
                     synaptosomal-associated protein, 91kDa homolog"
                     /codon_start=1
                     /product="clathrin coat assembly protein AP180 isoform o"
                     /protein_id="NP_001363631.1"
                     /db_xref="GeneID:9892"
                     /db_xref="HGNC:HGNC:14986"
                     /db_xref="MIM:607923"
                     /translation="MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDY
                     LIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNT
                     LFNLSNFLDKSGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMA
                     PEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINL
                     LEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLME
                     TLEQHLNTLEGKKPGNKSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASA
                     AVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSV
                     PSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFGDAFAASPGEAP
                     AASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTP
                     TASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDAF
                     SSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASE
                     PQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSS
                     SSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNL
                     GISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPP
                     VAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTP
                     ASQSPKKPPAKDPLADLNIKDFL"
     exon            229..371
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            372..447
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            448..550
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            551..644
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            645..756
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            757..863
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            864..905
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            906..976
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1004
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1114
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1233
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1248
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1416
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1524
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1788
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1860
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..1944
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2028
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2163
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2313
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2314..2344
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2456
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2457..2540
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2541..2645
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2748
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     exon            2749..4149
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4121..4126
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /note="hexamer: AATAAA"
     polyA_site      4149
                     /gene="SNAP91"
                     /gene_synonym="AP180; CALM"
                     /note="major polyA site"
ORIGIN      
        1 agtgcgtgcc gggtgcggcg ccagcagcgg aggggcggcc cggcgcccag cggagagccg
       61 ctggctggaa gaggaggcgg tagacgcgac cacagaagat gtcgggccaa acgctcacgg
      121 atcggatcgc cgccgctcag tacagcgtta caggctctgc tgtagcaaga gcggtctgca
      181 aagccactac tcatgaagta atgggcccca agaaaaagca cctggactat ttgatccagg
      241 ctaccaacga gaccaatgtt aatattcctc agatggccga cactctcttt gagcgggcaa
      301 caaacagtag ctgggtggtt gtgtttaagg ctttagtgac aacacatcat ctcatggtgc
      361 atggaaatga gagatttatt caatatttgg cttctagaaa tacactattc aatctcagca
      421 attttttgga caaaagtgga tcccatggtt atgatatgtc taccttcata aggcgctata
      481 gtagatattt gaatgaaaag gctttttctt acagacagat ggcctttgat tttgccaggg
      541 tgaagaaagg ggccgatggt gtaatgagga caatggctcc cgaaaagctg ctaaagagta
      601 tgccaatact acagggacaa attgatgcac tgcttgaatt tgatgtgcat ccaaatgaac
      661 taacaaatgg tgtcataaat gcagcattta tgcttctttt caaagatctt atcaaacttt
      721 ttgcttgcta caatgatggt gttattaact tactcgaaaa gttttttgaa atgaagaaag
      781 gacaatgtaa agatgctcta gaaatttaca aacgatttct aactagaatg acacgagtgt
      841 ctgaatttct caaggttgca gagcaagttg gtattgataa aggtgacatt cctgacctca
      901 cacaggctcc cagcagtctt atggagacgc ttgaacagca tctaaataca ttagaaggaa
      961 agaaacctgg aaacaaatct ggtgctccct ctccattaag taagtcttct ccagccacaa
     1021 ctgttacgtc tcctaattct acaccagcta aaactattga cacatcccca ccggttgatt
     1081 tatttgcaac tgcatctgcg gctgtcccag tcagcacttc taaaccatct agtgatctcc
     1141 tggacctcca gccagacttt tcctctggag gggcagcagc agccgcagca ccagcaccac
     1201 caccacctgc tggaggagcc actgcatggg gagacctttt gggagaggat tctttggctg
     1261 cactttcctc tgttccctct gaagcacaga tttcagatcc atttgcacca gaacctaccc
     1321 ctcctactac aactgctgaa attgcaactg cctcagcttc tgcctccact actacaactg
     1381 ttactgctgt cactgctgaa gtggatctct ttggagatgc ctttgcagct tctcctgggg
     1441 aggcccctgc agcatccgaa ggggccgccg caccagctac cccaacccct gtagcagcag
     1501 cacttgatgc atgttcagga aatgacccct ttgccccgtc tgaaggtagt gcagaggctg
     1561 cacctgagct ggacctcttt gcaatgaagc cacctgagac cagtgttcct gtagttaccc
     1621 ctacagctag cacagcccct ccagttcccg caactgctcc ttctcctgct cctgccgttg
     1681 cagctgctgc tgctgccact actgctgcca ccgccgctgc caccaccact accaccacct
     1741 ccgctgccac cgccaccact gctcctcctg ctctagatat ctttggtgat gctttctcct
     1801 ctccaccaca aggggcctct cctgtgcctg agagttctct cactgctgac ctcttatctg
     1861 tggatgcatt tgcagcacca tctcctgcaa ccactgcctc gccagcaaag gtggattctt
     1921 caggtgtcat agaccttttt ggggatgcat ttggaagtag tgcttctgaa ccccaacctg
     1981 catctcaggc tgcttctagt tcatcagcat cggcagacct actagctgga tttgggggtt
     2041 ctttcatggc gccttcccca tctccagtga ctccagctca gaataacctg ctacagccca
     2101 attttgaggc agcttttggg acaacgcctt caacttccag cagcagctcc tttgatccat
     2161 cagtgtttga tggtctaggt gatcttttga tgccaaccat ggcaccagct gggcagcctg
     2221 cacctgtctc aatggtacca cccagtcctg caatggcagc cagcaaagcc cttggaagtg
     2281 atcttgattc atctcttgcc agcttagtag gcaatcttgg aatttctggt accacaacaa
     2341 aaaagggaga tcttcagtgg aatgctggag agaaaaagtt gactggtgga gccaactggc
     2401 agcctaaagt agctccagca acctggtcag caggcgttcc accaagtgca cctttgcaag
     2461 gagctgtacc tccaaccagt tcagttcctc ctgttgccgg ggccccatcg gttggacaac
     2521 ctggagcagg atttggaatg cctcctgctg ggacaggcat gcccatgatg cctcagcagc
     2581 cggtcatgtt tgcacagccc atgatgaggc ccccctttgg agctgccgct gtacctggca
     2641 cgcagctttc tccaagccct acacctgcca gtcagagtcc caagaaacct ccagcaaagg
     2701 acccattagc ggatcttaac atcaaggatt tcttgtaaac aatttaagct gcaatatttg
     2761 tgactgaata ggaaaataaa tgagtttgga gacttcaaat aagattgatg ctgagtttca
     2821 aagggagcca ccagtaccaa acccaatact tactcataac ttctcttcca aaatgtgtaa
     2881 cacagccgtg aaagtgaaca ttaggaatat gtactacctt agctgttatc cctactcttg
     2941 aaattgtagt gtatttggat tatttgtgta ttgtacgatg taaacaatga atggatgtta
     3001 ctgatgccgt tagtgctttt ttggacttca cctgaggaca gatgatgcag ctgttgtgtg
     3061 gcgagctatt tggaaagacg tctgtgtttt tgaaggtttc aatgtacata taacttttga
     3121 acaaacccca aactcttccc ataaattatc ttttcttctg tatctctgtt acaagcgtag
     3181 tgtgataata ccagataata aggaaaacac tcataaatat acaaaacttt ttcagtgtgg
     3241 agtacatttt tccaatcaca ggaacttcaa ctgttgtgag aaatgtttat ttttgtggca
     3301 ctgtatatgt taagaaattt tattttaaaa aatataaagg ttaacgtcca taataaatac
     3361 ttctctttga agctacctta tcaagaacga aaaatcgtat gggaagaatc ccctatttat
     3421 cactgctata ttaaaatata tatattttaa ttatatttga caggttttgc atctaaattg
     3481 acctatttat tcattcttga ttaaatgcac tgaaaagtaa agggtctgtt tgtgtcatgt
     3541 tcatgaaaat gcggttagag aggtgctatt caagtgattc tgaaggcacc ccaaggtata
     3601 tctgtaattt aaagattact gcaaatatct ttactttact gtgggttttt agtacatctg
     3661 ttaatttagt gtttctttgt gtgttttgta gactagtgtt cttccatcct tcaactgagc
     3721 tcaaagtagg ttttgttgta acattgtgat taggatttaa actaattcag agaattgtat
     3781 cttttactgt acatactgta ttctttaagt tttaatttgt tgtcatactg tctgtgctga
     3841 tggcttggct taagattttg atgcataaat gaggtcactg ttgatcagtg ttgctagtag
     3901 cttggcagct cttcataaaa gcatattggg ttggaaaggt gtttgcctat ttttcaaatt
     3961 atttaataga tgtatggtac catttaaaag tggttgtatc tgaatttact gtggggataa
     4021 catacactgt aatggggaaa aattacctaa aaccaatttc aaaatggctt tctttgtatt
     4081 tcagtttaaa aacccagtgc atgtacgccc tctgagatgc aataaacacc ttgaacaaag
     4141 aaatgcaaa
//
