LOCUS       NM_001162936            1016 bp    mRNA    linear   PRI 13-OCT-2024
DEFINITION  Homo sapiens small integral membrane protein 9 (SMIM9), mRNA.
ACCESSION   NM_001162936
VERSION     NM_001162936.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
REFERENCE   2  (bases 1 to 1016)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109993.4.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 13, 2021 this sequence version replaced NM_001162936.3.
            
            ##Evidence-Data-START##
            CDS exon combination :: BX092805.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA1968968,
                                    SAMEA2142853 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000369529.2/ ENSP00000358542.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC109993.4         148546-148645       c
            101-210             AC109993.4         146557-146666       c
            211-451             AC109993.4         144698-144938       c
            452-581             AC109993.4         143518-143647       c
            582-1016            AC109993.4         137331-137765       c
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq28"
     gene            1..1016
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /note="small integral membrane protein 9"
                     /db_xref="GeneID:100132963"
                     /db_xref="HGNC:HGNC:41915"
     exon            1..100
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /inference="alignment:Splign:2.1.0"
     exon            101..210
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /inference="alignment:Splign:2.1.0"
     exon            211..451
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /inference="alignment:Splign:2.1.0"
     CDS             310..609
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /codon_start=1
                     /product="small integral membrane protein 9 precursor"
                     /protein_id="NP_001156408.1"
                     /db_xref="CCDS:CCDS55546.1"
                     /db_xref="GeneID:100132963"
                     /db_xref="HGNC:HGNC:41915"
                     /translation="MEPQKLLIIGFLLCSLTCLLLETVASSPLPLSALGIQEKTGSKP
                     RSGGNHRSWLNNFRDYLWQLIKSALPPAAIVAFLLTSALMGILCCFTILVVDPVH"
     exon            452..581
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /inference="alignment:Splign:2.1.0"
     exon            582..1016
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /inference="alignment:Splign:2.1.0"
     regulatory      714..719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /note="hexamer: ATTAAA"
     polyA_site      736
                     /gene="SMIM9"
                     /gene_synonym="CXorf68"
                     /note="major polyA site"
ORIGIN      
        1 atcctccagt acagtcaagc tttcagatga ctgcagtccc agcagataca tgactccaat
       61 ctcatcatcc actccaaaac taacctacag aaactataag agacctaagg agaagactga
      121 ccagcttctt ctgaagactt ctgccctcta aagactaagg cctaattcca ctggtttctt
      181 tgaattccgt ggtcctaagt ccattttcag acaaagtttc tgtggaaaga cctacggaca
      241 aagacatctc tccttggcag agtgagctag gattaccagc tcttcagccg cagctgaagg
      301 cgggagtcca tggaacccca gaagctgctg ataattggat ttctgctatg ctctctaact
      361 tgcctcttgt tggagacagt agcttcctct cctttgcctt tgtctgcctt gggaatacaa
      421 gaaaaaacag gatcgaaacc acgctcaggg ggtaatcaca ggtcctggct gaacaacttc
      481 agggattact tatggcaact tatcaagagt gccttacctc cagcagccat tgttgctttt
      541 cttctcacct cagcactaat ggggatcctc tgctgcttca ccattcttgt agttgatcca
      601 gtccactgaa gaactagaag attcaacagg gcaagtgtgg tctctccagt tggactccaa
      661 aagagtgggg catttgctat ctgcttaaaa tgaggaagta tctatcagtt gaaattaaat
      721 cgtcttccaa cttgaatcat cctttgcctt cattttctcc ttcaaaagtt gcaattttaa
      781 aatgtgaata tccttattac tgttttggtt ataatagtaa tacatattta ttgcaaaaaa
      841 aatttgagaa atacagagaa aagagtaagt ttccataatt ctagcaacca gaaataaaca
      901 tcattaacat cttgatgtac ctcccttcaa tttttttcta tatatgtatt acaagttttc
      961 caaagtctgt tctgtgaaac aatagttctg ttttaataaa agtcacaaaa cagtga
//
