LOCUS       NM_001162995            1546 bp    mRNA    linear   PRI 11-JUN-2024
DEFINITION  Homo sapiens small integral membrane protein 5 (SMIM5), transcript
            variant 1, mRNA.
ACCESSION   NM_001162995 NR_024379
VERSION     NM_001162995.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1546)
  AUTHORS   Zodro,E., Jaroszewski,M., Ida,A., Wrzesinski,T., Kwias,Z.,
            Bluyssen,H. and Wesoly,J.
  TITLE     FUT11 as a potential biomarker of clear cell renal cell carcinoma
            progression based on meta-analysis of gene expression data
  JOURNAL   Tumour Biol 35 (3), 2607-2617 (2014)
   PUBMED   24318988
REFERENCE   3  (bases 1 to 1546)
  AUTHORS   Wistow,G., Bernstein,S.L., Wyatt,M.K., Fariss,R.N., Behal,A.,
            Touchman,J.W., Bouffard,G., Smith,D. and Peterson,K.
  TITLE     Expressed sequence tag analysis of human RPE/choroid for the
            NEIBank Project: over 6000 non-redundant transcripts, novel genes
            and splice variants
  JOURNAL   Mol Vis 8, 205-220 (2002)
   PUBMED   12107410
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC027861.1, BI712658.1 and CA413024.1.
            
            On Aug 11, 2020 this sequence version replaced NM_001162995.2.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027861.1, SRR3476690.462807.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375215.3/ ENSP00000364363.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-654               BC027861.1         1-654
            655-1265            BI712658.1         18-628
            1266-1546           CA413024.1         21-301              c
FEATURES             Location/Qualifiers
     source          1..1546
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.1"
     gene            1..1546
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /note="small integral membrane protein 5"
                     /db_xref="GeneID:643008"
                     /db_xref="HGNC:HGNC:40030"
     exon            1..769
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /inference="alignment:Splign:2.1.0"
     exon            770..932
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /inference="alignment:Splign:2.1.0"
     CDS             806..1039
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /codon_start=1
                     /product="small integral membrane protein 5"
                     /protein_id="NP_001156467.1"
                     /db_xref="CCDS:CCDS54165.1"
                     /db_xref="GeneID:643008"
                     /db_xref="HGNC:HGNC:40030"
                     /translation="MAATDFVQEMRAVGERLLLKLQRLPQAEPVEIVAFSVIILFTAT
                     VLLLLLIACSCCCTHCCCPERRGRKVQVQPTPP"
     exon            933..1546
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1524..1529
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /note="hexamer: AGTAAA"
     polyA_site      1546
                     /gene="SMIM5"
                     /gene_synonym="C17orf109; PP12104"
                     /note="major polyA site"
ORIGIN      
        1 cacagcccca gcagaaggcc ctcacctcac aaggaacatg aggcgccttg ccgggcgcgc
       61 aggccactcc caggtcactc aggattccaa gttctccccc aagacgcctt cagatgctga
      121 gcggcacaag ggcctcccca gggactggtt gcaaagcctc ctgctcagct tgagagggcc
      181 accagctccc cactgtttac tgttgttcct gagagaggcc agagggaggg accagccagg
      241 gagtggccag agggacagaa ggggtggcct tcctgagggc agggtgggtg ccccagacct
      301 gagagcgctg caggactccc ctccacaggc tcaggtggag cctccccagg gtcctcctgg
      361 ccaggaaggc agagagccga cttctttctt cagctcccaa cccaggccca gcccacggcg
      421 tgggagtcgg ggagagggag aggaggagga aggaggagga gagagggagc ttgtcttgtc
      481 cctgagcagc gctctcaggg cagaggtgag gcaccgggac atgaagttgg aggacaagtt
      541 cccaagcagg gcttcctcgg gctccccctc gcgacggtaa tttgacactt ggatctccag
      601 gacgaccaac aacaaaaaag ccaggcagag acagcagctg gctgtcagca gaggagctgg
      661 gctgaggcgc ccaggggagc agcggcgccc acgaaggaag tacgaggaca gcacgtggag
      721 gctccgcgct ggggcactgc tgctcagccc ccaacacctg agctcccaga gcccggcagg
      781 agccccaaca ggaagccagc gcggcatggc tgccaccgac ttcgtgcagg agatgcgcgc
      841 cgtgggcgag aggctgctgc tcaagctgca gagactgccc caggctgagc ccgtggagat
      901 cgtggccttc tcagtcatca tccttttcac agctactgtt ctgctgttgc tgctgatagc
      961 ctgcagctgc tgctgcactc actgctgctg ccctgagcgg agaggcagga aggtccaggt
     1021 gcagccgaca ccaccatgac ggacgggcga tggctgagga gaagctggag aggagatggc
     1081 caatgccatg acacaggcca tcagcctggc cctgcagccc ttacccctca agaccaggct
     1141 cccctggccc cagctctggc ccagcccagg tacctggaca ctgacaactt gagccctacc
     1201 aaggaaacaa gggctggtat aggtgcaaac ctctcatctg ccagtggaca ctgggtgctg
     1261 gggagtcagc tgtttcaaag actgggtcaa ctgcctgggc ttcttcgcct acctgcactt
     1321 tttaacaaaa caaggaagta ggggtcccca taccttgatg gagaacagtc cccacctgtg
     1381 ggcaattggc ccttggggct ctgctgatac atgccaaaga ggagcaaggc aatcagaggg
     1441 gctttgtgca atagcttctg catccgagct cccgccagag cgtgagcatg tcagtattct
     1501 agtccagtat ttgccagttt ccaagtaaaa gcttttgtgt tacgtg
//
