LOCUS       NM_001394165            3240 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens small integral membrane protein 35 (SMIM35),
            transcript variant 3, mRNA.
ACCESSION   NM_001394165
VERSION     NM_001394165.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000665.5 and AP002962.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.432331.1,
                                           SRR14038196.227323.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1970526 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000689828.1/ ENSP00000509259.1
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-213               AP000665.5         97396-97608         c
            214-330             AP002962.2         130690-130806       c
            331-364             AP002962.2         129705-129738       c
            365-497             AP002962.2         128745-128877       c
            498-3240            AP002962.2         118631-121373       c
FEATURES             Location/Qualifiers
     source          1..3240
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q23.3"
     gene            1..3240
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /note="small integral membrane protein 35"
                     /db_xref="GeneID:100526771"
                     /db_xref="HGNC:HGNC:44179"
     exon            1..213
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..464
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /note="isoform 3 is encoded by transcript variant 3;
                     TMPRSS4 antisense RNA 1 (non-protein coding)"
                     /codon_start=1
                     /product="small integral membrane protein 35 isoform 3"
                     /protein_id="NP_001381094.1"
                     /db_xref="CCDS:CCDS91602.1"
                     /db_xref="GeneID:100526771"
                     /db_xref="HGNC:HGNC:44179"
                     /translation="MTGEDSISTLGLILGVGLLLLLVSILGYSLAKWYQRGYCWEGPN
                     FVFNLYQIRNLKDLEMGPPFTISGHISSTDGGYMKFSNGLV"
     exon            214..330
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            331..364
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            365..497
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            498..3240
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3221..3226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /note="hexamer: AATAAA"
     polyA_site      3240
                     /gene="SMIM35"
                     /gene_synonym="TMPRSS4-AS1"
                     /note="major polyA site"
ORIGIN      
        1 agaggtgctt gccgtcagct tgcagagtgg ggcccggcca cagtgctcct ctgagggagc
       61 ctcactctgc tctctgaccc cagaacctgc atccctcccc aaaaccaacg gcaagcagct
      121 gtgtcctctc cacttgcagc tggaataggc agtttgatgc ctttgctgcg ctggcaacag
      181 ggctctctct cttggatgtc tcagccatga caggtgagga ctccatcagc accttgggcc
      241 tgatccttgg cgtggggctc ttgctgctgc tcgtgtccat cctcggctac agcctggcca
      301 agtggtacca gcgcgggtac tgctgggagg ggcctaattt tgtcttcaac ttatatcaaa
      361 tccggaacct gaaggatctg gagatgggtc cacccttcac catcagtggt cacatcagca
      421 gcacagatgg tggctacatg aagttctcca acgggctagt ctgatgcaga gacagcaact
      481 tgtgaagccc tggggagatg agaagactga ggcccagaac tgacatgaca gtttcatgtg
      541 gagagaacag aaagtggctg agcattcttt ctactccctg gggctgttgc ctcttcctct
      601 ttgcctttgg agcatttcca gaccaacaag cttgctgcgg cagtccatcc ggccattcgc
      661 atattatagc ataccatgtg cggggtgtcc ctggagctgt cagtgctgca gaagcagttg
      721 gaagtggagt cagtgagtct ttcaattctt tcaaaaagtt gattgtgaag gatgggagag
      781 aaggtggtgc tggccagtaa gttttcagaa cctttgtctt gtcttcccca aggaggcctc
      841 ccagaaagcg ccagctgggc caaatgcccg ctctccacac gccatcgacc cctgtgcaca
      901 tccccatgac agcccataca gtcggtgcct cccgtcctcc tggcctgaca aagtctcgtc
      961 tgcagtgccc actgcctgcc atctgcttac tgcccagctc ctccagttct gggggagccc
     1021 atgcagctct gtgcactgca tcaggaggac tgcggtatgg agattagact gagggagcag
     1081 gagtggatgc agaggagcag gacagagcct catggtggtc caggggagag gtgaagatga
     1141 atttgaccag atgacagtgg gaggtggtga caagtgattg gattcaccat ctatctggaa
     1201 ggtagagctg ataggactta ctaaggagtt tgatggggca gaaagggctg actcctggat
     1261 ttttggcctg aactagggga aaggtggtgc catttatcag gtggggaaga ctaggggagg
     1321 aaggagtgtc aggggaatca tgagctctgt tgtagacact ataattttga gatgtatgct
     1381 ggacggagct gctgatgagg cagctggata gagttctgga gagaaaccct gtttggacat
     1441 ttggaagcca ccagcatcca gataacactt aaaggtgtgg actgggtgat aacaagtagg
     1501 gggcagtgag gagaaaaagg actgatttta atagaacaag cagcgaatca acaagttgtt
     1561 ccttaaagag gtgactcagt gtgtgctgga atcacctgca atgtggtcgc tataagttgt
     1621 ttccctagca ggtccttggg aaccggtatt cagaaattct gggccttggg gagcagctta
     1681 ggaagacaaa tactcccatg taattctgat agaggcaatc ttctgagaaa ctctgcctta
     1741 ggggacaggt agaggggatg tggggaggtg gagggcaagg gtcacttcca gggctggggt
     1801 gaccagatag taggattctg aagaatgttc ctgttctctc cagggtcact gtgaggtctt
     1861 aatctccacc acgcccttct gccccatgtg ggtagaggta gacaggtgtg gcaccctaca
     1921 cccaggcctt tgcagatcat gtactagtct gtacccctcc ctgagcctct cagctctaca
     1981 gattagacaa cttactaaag ggagccctca gctgcaccct tgatgatggg ctgtgattga
     2041 ccaaggagcc ccagtgaggc tcctggctgg gctctgcaag acagatgcca aacacagccg
     2101 tggctcctgt gactcgatga gttgaaggga tggcagcctg cttttcctca aggcaggaag
     2161 tcatcgcgtg aatattctaa ctgtattggc tgcaggggtt tggggatctt ctccaagccg
     2221 gcgtccttac cttcacacta agggctatga gctcattcac tctcacatgg gaatccctaa
     2281 ccctgagcct cacagatcca ggccagcctt gccaattgct gaaagacctt ttcttggatg
     2341 acttgtcatt attaagccag aactcatcat ctcccctctc cctccacacc tctgtctccc
     2401 ttccatgtcc atatttcgct tttctcatca tcgggttcaa gtgtgactag cacttctgag
     2461 acctccttct ttcactccag cctgttgccc catcttgata atgcttcctt taaaatgtct
     2521 ttgagtctgt ccctttctct ctgttcccac tgcccctgct caatactgtc atttgattag
     2581 actattgtat aagcctctct tatgaactga atatttttgt cttccccaaa ttcatgttga
     2641 agctgtcact cccaatgtga cggtatttgg aggtaaagcc tctgggaggt aattggttta
     2701 gatgaggtca tgaggatggg gcctccatga tgggattagt gcccttgtaa gaaagtggaa
     2761 gagagaccag agttctttat ctccaccgtg taaggccaca gcaagaagga ggccgtctcc
     2821 aagccaggaa gagagccctc ccagggaact cactcagctg gcaccttgat cctgcacttc
     2881 cccacctcca gaactgtgag agataaatgt ctgttgttta agccacccag tccatggtgt
     2941 tttgttatag tagcccagcc taagacagcc tcctaccctg tttctctgcc tcctgcctca
     3001 tccttcatgt ggaatactag tttctttcac atcacttatc actgattgta gtaatacgtt
     3061 tgttgtgttt atttgcttgg tgtttatctt cataaccaga tgacaggctc catgaagcca
     3121 cacttgtttg gttcaccact ctgtacccag ggctgcacac catgtccaac acataacaag
     3181 tgcttcgtaa tgttttttga caaaatgaaa tgctgactac aataaaagtc tccagccagg
//
