LOCUS       NM_024058               1215 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens small integral membrane protein 2 (SMIM2), mRNA.
ACCESSION   NM_024058 XR_159007 XR_159230 XR_172002
VERSION     NM_024058.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC000868.1 and AL589745.8.
            
            On May 17, 2019 this sequence version replaced NM_024058.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC000868.1, BE544712.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000400419.2/ ENSP00000383270.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1214              BC000868.1         1-1214
            1215-1215           AL589745.8         52524-52524         c
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.11"
     gene            1..1215
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /note="small integral membrane protein 2"
                     /db_xref="GeneID:79024"
                     /db_xref="HGNC:HGNC:28776"
     exon            1..113
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /inference="alignment:Splign:2.1.0"
     exon            114..442
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..447
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /codon_start=1
                     /product="small integral membrane protein 2"
                     /protein_id="NP_076963.1"
                     /db_xref="CCDS:CCDS61320.1"
                     /db_xref="GeneID:79024"
                     /db_xref="HGNC:HGNC:28776"
                     /translation="MEAGERIDASQLPHRVLETRGHAISILFGFWTSFICDTYIVLAW
                     ISKIKGSPDVSASSDEPYARIQQSRRQCHAEEDQSQVPEAG"
     exon            443..1215
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1190..1195
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /note="hexamer: AATAAA"
     polyA_site      1215
                     /gene="SMIM2"
                     /gene_synonym="C13orf44"
                     /note="major polyA site"
ORIGIN      
        1 gtgttcatgg gcctcattaa gctctgcctt ccttctgctt tttggagcct ggcctttggt
       61 tggccttgaa tgaagagtgg ggccccaaaa gtaccactgt cagcactctc cagcatcatc
      121 tggctgtctg gcaccatcaa agaattgcat ttctgaccca agaagagctt atgggtggat
      181 gggggtggga tggaagctgg ggagaggatt gatgccagcc agctgcctca cagggtgctg
      241 gaaacacgtg gccatgccat tagcatcctg ttcggcttct ggacgagttt catctgtgac
      301 acctacatag tcctcgcttg gatcagcaag ataaaaggca gccctgatgt tagtgcctcc
      361 tctgatgagc catacgccag aatccagcag agcagaaggc aatgccacgc agaagaggac
      421 caaagtcagg tgccagaagc aggctgacct ggaaaggtgg aggaaaagaa ggcagaaggg
      481 agagatgaag cccaagaacc tgagtatttt tctcaggcaa gactcaggac tgctctggac
      541 attcagaagc tgagtgtgca agtgtgctgt gtagttcaag gccaccacca ctgaagaggc
      601 caaggacacc ttagtaggaa ttctaacctg gcttccaggg agaggtgctt ccaaattggc
      661 cctgtaggca aattcacttt tttcaccctc taagcgagta agtgcttgtt cccaatttcc
      721 atggtttagt cttcagtttc agtctttggt ctcctctggt ctatcagctc ccatctctct
      781 cccagtcttt ttctttattc tgtgacacct gttgaatgag gcacataggg tttgtagtca
      841 ctgtagtgtt ccttgtggtt gtgaggtaat aggctaatat tatcactttc tcagaaagtc
      901 ttcaaaatta tcatgaggag gtgatgcatt catctgctgg gaggtgtctg tgtggtcaga
      961 taagatgatg gctacattcc attcctatcc tgtcattcaa tcattcttcc tccagggagc
     1021 cactgaggga cgtgatagtc caaagcactc agctaaaacg gaattgcaaa catggtaccc
     1081 acaactttgg tttcttatca tccatttgta tatctgcatg tagtctgtct ctgatttagg
     1141 gtttaggttc ctctgtattt ttttttcttt tcctgccctt tgagagttta ataaaagcca
     1201 gaagcatctt gtaaa
//
