LOCUS       NM_001206847             925 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens small integral membrane protein 18 (SMIM18), mRNA.
ACCESSION   NM_001206847 XR_110874 XR_113126 XR_114163
VERSION     NM_001206847.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Cirulli,E.T., Kasperaviciute,D., Attix,D.K., Need,A.C., Ge,D.,
            Gibson,G. and Goldstein,D.B.
  TITLE     Common genetic variation and performance on standardized cognitive
            tests
  JOURNAL   Eur J Hum Genet 18 (7), 815-820 (2010)
   PUBMED   20125193
  REMARK    Erratum:[Eur J Hum Genet. 2010 Jul;18(7):820]
REFERENCE   2  (bases 1 to 925)
  AUTHORS   Dalla,E., Mignone,F., Verardo,R., Marchionni,L., Marzinotto,S.,
            Lazarevic,D., Reid,J.F., Marzio,R., Klaric,E., Licastro,D.,
            Marcuzzi,G., Gambetta,R., Pierotti,M.A., Pesole,G. and Schneider,C.
  TITLE     Discovery of 342 putative new genes from the analysis of
            5'-end-sequenced full-length-enriched cDNA human transcripts
  JOURNAL   Genomics 85 (6), 739-751 (2005)
   PUBMED   15885500
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102945.2, DR033682.1, BM710955.1 and AC103959.18.
            
            On May 17, 2019 this sequence version replaced NM_001206847.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.97632.1,
                                           SRR1660807.18194.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145544
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000517349.2/ ENSP00000428858.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AC102945.2         121650-121669
            21-22               DR033682.1         12-13
            23-486              BM710955.1         1-464
            487-925             AC103959.18        62195-62633
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p12"
     gene            1..925
                     /gene="SMIM18"
                     /note="small integral membrane protein 18"
                     /db_xref="GeneID:100507341"
                     /db_xref="HGNC:HGNC:42973"
     exon            1..60
                     /gene="SMIM18"
                     /inference="alignment:Splign:2.1.0"
     exon            61..141
                     /gene="SMIM18"
                     /inference="alignment:Splign:2.1.0"
     exon            142..925
                     /gene="SMIM18"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..458
                     /gene="SMIM18"
                     /codon_start=1
                     /product="small integral membrane protein 18"
                     /protein_id="NP_001193776.1"
                     /db_xref="CCDS:CCDS56529.1"
                     /db_xref="GeneID:100507341"
                     /db_xref="HGNC:HGNC:42973"
                     /translation="MASSHWNETTTSVYQYLGFQVQKIYPFHDNWNTACFVILLLFIF
                     TVVSLVVLAFLYEVLDCCCCVKNKTVKDLKSEPNPLRSMMDNIRKRETEVV"
     regulatory      638..643
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM18"
                     /note="hexamer: AATATA"
     regulatory      645..650
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM18"
                     /note="hexamer: AGTAAA"
     polyA_site      656
                     /gene="SMIM18"
                     /note="major polyA site"
     polyA_site      666
                     /gene="SMIM18"
ORIGIN      
        1 actagactgc attacaaaca gacgatacca tcgcttcagc agcatcctct cagacaagag
       61 ccactatttc tgattcagat cacctgtcat cgaagtttaa agaaggggaa acaggagaca
      121 gaaatacact gaaccaaaaa gattcaaaag agcaagtgga atctctaaga atggcttcca
      181 gccactggaa tgaaaccact acctctgttt atcagtacct tggttttcaa gttcaaaaaa
      241 tttacccttt ccatgacaac tggaacactg cctgctttgt catcctgctt ttatttatat
      301 ttacagtggt atctttagtg gtgctggctt tcctttatga agtgcttgac tgctgctgct
      361 gtgtaaaaaa caaaaccgtg aaagacttga aaagtgaacc caaccctctt agaagtatga
      421 tggacaacat cagaaaacgt gaaactgaag tggtctaaca ctctatagaa gatgaacaaa
      481 atctctgaaa gcagctcaac ctcttctgag aaaaaaaata tattctgagg ccaactgttg
      541 ctacaaaaca aattctgact gaatggttaa aacatttcta gtagaagggg aaaaaaaagt
      601 taaacatgca ctgtttgtgt gtatagccat ttcattaaat atacagtaaa acttcatgaa
      661 tgtgaattta ctaatctgtt taatactgac acttcaaaaa ctggataaaa gattcctaga
      721 gttcaatatt aagcagcaaa agataagctg gaaaagacaa gcaaggctaa tgatgctaaa
      781 atgattttat aactaaccaa ttcatgtaga caaaaaatag tgtgttggta acaaaaaggc
      841 tatttaaaac atgtttctaa gtctgaagta aaatacttcc acttatatat ataaagttcc
      901 tatttattaa aaagtagtat tttct
//
